VirologiePub Date : 2025-04-02DOI: 10.1684/vir.2025.1080
Pierre Lebon, Paul Mandon, Henri Agut
{"title":"[Attachment to red blood cells, a very useful property of certain viruses].","authors":"Pierre Lebon, Paul Mandon, Henri Agut","doi":"10.1684/vir.2025.1080","DOIUrl":"https://doi.org/10.1684/vir.2025.1080","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 3","pages":"0"},"PeriodicalIF":0.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-01DOI: 10.1684/vir.2025.1078
Hélène Dutartre, Francesca Fiorini, Denis Gerlier, Henri Gruffat, Patrick Lomonte, Pierre-Yves Lozach, Mathieu Mateo
{"title":"[Lyon, at the center of the global virology research challenge].","authors":"Hélène Dutartre, Francesca Fiorini, Denis Gerlier, Henri Gruffat, Patrick Lomonte, Pierre-Yves Lozach, Mathieu Mateo","doi":"10.1684/vir.2025.1078","DOIUrl":"https://doi.org/10.1684/vir.2025.1078","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 2","pages":"59-63"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-01DOI: 10.1684/vir.2025.1081
{"title":"Programme des XXVIIes Journées francophones de virology 23, 24 & 25 avril 2025.","authors":"","doi":"10.1684/vir.2025.1081","DOIUrl":"10.1684/vir.2025.1081","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 2","pages":"68-69"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-04-01DOI: 10.1684/vir.2025.1083
{"title":"Index par auteur et par numéro de résumé.","authors":"","doi":"10.1684/vir.2025.1083","DOIUrl":"https://doi.org/10.1684/vir.2025.1083","url":null,"abstract":"","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 2","pages":"170-175"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-02-01DOI: 10.1684/vir.2025.1073
Mariangela Cavarelli
{"title":"[Ghosts of the virus : unmasking the persistent threat of SARS-CoV-2 in Long COVID].","authors":"Mariangela Cavarelli","doi":"10.1684/vir.2025.1073","DOIUrl":"10.1684/vir.2025.1073","url":null,"abstract":"<p><p>Long COVID has emerged as a debilitating condition, severely impacting the daily functioning and quality of life of affected individuals. The pathogenesis of Long COVID is complex and multifactorial, involving immune dysregulation, persistent inflammation, and potential reactivation of other pathogens. A key driver of Long COVID is the potential persistence of SARS-CoV-2 in various tissues beyond the respiratory tract, leading to the formation of viral reservoirs that contribute to ongoing symptoms, several months after initial infection. These reservoirs have been suggested in the gastrointestinal tract, central nervous system, cardiovascular system, and other tissues, often persisting months after the initial infection. Additionally, viral RNA and proteins in these tissues are associated with chronic inflammation and immune system disruptions, which are primary contributors to Long COVID symptoms. This article explores the mechanisms and consequences of SARS-CoV-2 persistence in respiratory and non-respiratory tissues, highlighting its impact on the immune system and underscoring critical areas for future research to improve outcomes for individuals suffering from Long COVID.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 1","pages":"41-53"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VirologiePub Date : 2025-02-01DOI: 10.1684/vir.2025.1074
Mariangela Cavarelli
{"title":"Ghosts of the virus : unmasking the persistent threat of SARS-CoV-2 in Long COVID.","authors":"Mariangela Cavarelli","doi":"10.1684/vir.2025.1074","DOIUrl":"10.1684/vir.2025.1074","url":null,"abstract":"<p><p>Long COVID has emerged as a debilitating condition, severely impacting the daily functioning and quality of life of affected individuals. The pathogenesis of Long COVID is complex and multifactorial, involving immune dysregulation, persistent inflammation, and potential reactivation of other pathogens. A key driver of Long COVID is the potential persistence of SARS-CoV-2 in various tissues beyond the respiratory tract, leading to the formation of viral reservoirs that contribute to ongoing symptoms, several months after initial infection. These reservoirs have been suggested in the gastrointestinal tract, central nervous system, cardiovascular system, and other tissues, often persisting months after the initial infection. Additionally, viral RNA and proteins in these tissues are associated with chronic inflammation and immune system disruptions, which are primary contributors to Long COVID symptoms. This article explores the mechanisms and consequences of SARS-CoV-2 persistence in respiratory and non-respiratory tissues, highlighting its impact on the immune system and underscoring critical areas for future research to improve outcomes for individuals suffering from Long COVID.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 1","pages":"57-68"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Deciphering the links between hepatic viruses and interferons: molecular interactions and therapeutic implications].","authors":"Cassandre Authier, Claudie Eber, Roxanne Fouillé, Julie Lucifora, Eloi R Verrier","doi":"10.1684/vir.2025.1076","DOIUrl":"10.1684/vir.2025.1076","url":null,"abstract":"<p><p>Interferons (IFNs) are cytokines that play a key role in the innate immune response, possessing antiviral, antiproliferative, and immunomodulatory properties. Currently, IFNs are used clinically as treatments for lymphomas, multiple sclerosis, and chronic viral infections such as hepatitis B, C, D, and E virus infections. HEV infection can lead to fulminant hepatitis, while chronic infections with HBV, HCV, and HDV are the leading global causes of hepatocellular carcinoma. Despite their limited efficacy and numerous side effects, IFNs remain essential in the treatment of these infections. In this review, we summarize the current knowledge on the interactions between hepatic viruses and the IFN pathway to understand the virus-dependent molecular mechanisms involved in IFN induction and its antiviral effects.</p>","PeriodicalId":49377,"journal":{"name":"Virologie","volume":"29 1","pages":"19-39"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}