West Indian Medical Journal最新文献_第2页

Paraquat-induced Thrombotic Microangiopathy: The Pathophysiology in Hyperacute Paraquat Poisoning Deaths 百草枯致血栓性微血管病：百草枯超急性中毒死亡的病理生理学

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-12-27 DOI: 10.7727/WIMJ.2018.141

H. Daisley, A. Rampersad, O. Acco, D. Meyers

引用次数: 0

Stemming the Brain Drain from the Caribbean Postgraduate Medical Education at The University of the West Indies Reform and Expansion of the Faculty of Medicine 阻止西印度群岛大学加勒比研究生医学教育的人才流失改革和扩大医学院

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-11-19 DOI: 10.7727/wimj.2018.127

M. Ragbeer

引用次数: 0

Chikungunya Virus Infection-associated Arthralgia in Adult Jamaicans Post-outbreak 暴发后牙买加成年人基孔肯雅病毒感染相关的关节痛

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-10-18 DOI: 10.7727/wimj.2018.090

O. O’Sullivan, T. Campbell, A. Darby, N. Mourillon, J. Campbell, T. Melbourne, V. Green, Jackson

{"title":"Chikungunya Virus Infection-associated Arthralgia in Adult Jamaicans Post-outbreak","authors":"O. O’Sullivan, T. Campbell, A. Darby, N. Mourillon, J. Campbell, T. Melbourne, V. Green, Jackson","doi":"10.7727/wimj.2018.090","DOIUrl":"https://doi.org/10.7727/wimj.2018.090","url":null,"abstract":"Objective: To report demographic and self-reported clinical characteristics associated with persistent and severe arthralgia 8–12 months post-chikungunya virus (CHIKV) infection. Methods: A cross-sectional study of 306 adults who self-reported CHIKV infection was conducted. Subjects were consecutively enrolled at public primary healthcare centres in urban and rural areas in Jamaica. Adults with arthralgic conditions were compared with those who reported no arthralgia. Binary logistic regression models were used to determine demographic and self-reported clinical factors associated with severe arthralgia and persistent arthralgia. Results: Most subjects (70.3%) reported arthralgia after CHIKV outbreak (age: 47.6 ± 18.5 years). Medical consultation (36.2%) and laboratory confirmation (1.4%) were low. The prevalence of persistent and severe arthralgia in the previous month was 30.3% and 27.5%, respectively. Severe arthralgia was associated with the female gender (odds ratio (OR): 2.44; 95% confidence level (CI): 1.08, 5.52) and pre-existing arthritis (OR: 3.78; 95% CI: 1.23, 11.62). Females showed a greater likelihood of persistent arthralgia (OR: 2.18; 95% CI: 1.09, 4.39). Conclusion: Self-perceived arthralgia was an important feature 8–12 months post-CHIKV infection and has implications for the recognition and management of arthritis/rheumatic conditions.","PeriodicalId":49366,"journal":{"name":"West Indian Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2018-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41601515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Prevalence of Methicillin-resistant Staphylococcus aureus in the Surgical Wards ofthe Port-of-Spain General Hospital, Trinidad and Tobago 特立尼达和多巴哥西班牙港总医院外科病房耐甲氧西林金黄色葡萄球菌的患病率

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-04-22 DOI: 10.7727/wimj.2016.311

Mj Ramdass, S. Balliram, A. Cadan, N. Bhaggan, B. Mohammed, R. Singh, J. Maharaj, A. Boodram

引用次数: 2

Evaluation of hβD-1 and hβD-2 levels in saliva of patients with oral mucosal diseases 口腔黏膜疾病患者唾液中hβD-1和hβD-2水平的评价

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-03-21 DOI: 10.7727/WIMJ.2012.315

Hasan Küçükkolbaşı, S. Kucukkolbasi, H. Ayyildiz, R. Dursun, H. Kara

{"title":"Evaluation of hβD-1 and hβD-2 levels in saliva of patients with oral mucosal diseases","authors":"Hasan Küçükkolbaşı, S. Kucukkolbasi, H. Ayyildiz, R. Dursun, H. Kara","doi":"10.7727/WIMJ.2012.315","DOIUrl":"https://doi.org/10.7727/WIMJ.2012.315","url":null,"abstract":"OBJECTIVE This study aimed to determine a possible correlation between oral mucosal disease and salivary concentrations of the antimicrobial peptides human beta-defensin-1 (hbetaD-1) and human beta-defensin-2 (hbetaD-2). METHOD The present work focussed on the establishment of a reversed phase-high performance liquid chromatography (RP-HPLC) procedure to quantify human beta-defensins (hbetaD-1 and hbetaD-2) in saliva samples of patients with oral diseases such as lichen planus (n = 10), Behcet (n = 10) and recurrent apthous stomatitis (n = 10). RESULTS Linear calibration range for hbetaD-1 and hbetaD-2 defensins was 1.67-200 microg mL-1 and 3.13 -100 PG mL-1 with R2 values of 0.9998 and 0.996, correspondingly. The concentration of beta-defensins in saliva was determined by comparing the peak areas of eluted hbetaD-1 and hbetaD-2 with that of their standards. The variation of the amount of beta-defensins was evaluated by comparisons of the results obtained from the patients with oral mucosal diseases before and after treatments and the control subjects. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 1.62 microg mL-Sand 5.39 microg mL-1 for hbetaD-1 and 0.94 mig mL-1 and 3.13 microg mL-1 for hbetalD-2, respectively. CONCLUSION The salivary beta-defensin concentration was significantly higher in patients with oral mucosal diseases than in healthy volunteers; furthermore, in patients with oral mucosal diseases, the concentration was significantly higher before treatment than after treatment.","PeriodicalId":49366,"journal":{"name":"West Indian Medical Journal","volume":"62 1","pages":"230-238"},"PeriodicalIF":0.1,"publicationDate":"2018-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44816283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Herbs that Ensure Good Health and Longevity. 确保健康和长寿的草药。

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-03-21 DOI: 10.7727/WIMJ.2013.153

J. Jainarinesingh

引用次数: 3

Urinary Advanced Oxidation Protein Product: A Potential Oxidative Damage Marker for Cancer 尿晚期氧化蛋白产物：癌症潜在的氧化损伤标志物

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-03-21 DOI: 10.7727/WIMJ.2012.324

S. Chandramathi, K. Suresh, Z. B. Anita, U. Kuppusamy

{"title":"Urinary Advanced Oxidation Protein Product: A Potential Oxidative Damage Marker for Cancer","authors":"S. Chandramathi, K. Suresh, Z. B. Anita, U. Kuppusamy","doi":"10.7727/WIMJ.2012.324","DOIUrl":"https://doi.org/10.7727/WIMJ.2012.324","url":null,"abstract":"Objective: Oxidative stress has been implicated in the pathophysiology of various life threatening diseases namely cancer, cardiovascular disease and diabetes. This study aims to compare the severity of oxidative damage in cancer and some factors that may influence the levels of urinary oxidative biomarkers. The factors were sample collection period, cancer stages and lifestyle disease conditions (which are known to be associated with oxidative stress) such as diabetes with and without hypertension. Methods: The effects of the above mentioned factors on the levels of urinary advanced oxidation protein product (AOPP) and other oxidative indices such as hydrogen peroxide (H2O2), malondialdehyde (MDA) and ferric-reducing antioxidant power (FRAP) were evaluated according to well-established methods. Results: The period of sample collection did not show any significant difference in the parameters tested. The levels of oxidative stress in breast and colorectal cancer patients that generally increased with the cancer stages showed that cancer progression correlates with high oxidative damage. Comparison between diabetes with and without hypertension did not give any significant difference in the parameters tested. Among all the four oxidative indices, the level of AOPP in breast, colorectal and other types of cancers were significantly higher compared to diabetes with or without hypertension. Conclusions: The oxidative damage to protein is significantly higher in cancer and may potentially serve as a non-invasive oxidative biomarker for this disease.","PeriodicalId":49366,"journal":{"name":"West Indian Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2018-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46959683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Agreement, Time and Cost Comparison for the Identification of Gram Negative Bacteria Isolates Using VITEK® 2 Compact, VITEK® 60, VITEK® Mass Spectrometry and API® 20E/NE 使用VITEK®2 Compact、VITEK™60、VITEK®质谱法和API®20E/NE鉴定革兰氏阴性菌分离物的协议、时间和成本比较

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-01-26 DOI: 10.7727/WIMJ.2017.139

R. Nagassar, N. Christian, R. Gorton, B. Willey, T. Mazzulli

引用次数: 0

The Case of Squamous Cell Carcinoma Accompanied Leukemoid Reaction. 鳞状细胞癌伴白血病反应1例。

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-01-26 DOI: 10.7727/wimj.2015.137

Z. Urakçı, M. Kaplan, M. Kuçukoner, A. Dogan, Z. Oruç, Zincircioğlu Sb, E. Bodakçı, N. Akdeniz, A. Işıkdoğan

{"title":"The Case of Squamous Cell Carcinoma Accompanied Leukemoid Reaction.","authors":"Z. Urakçı, M. Kaplan, M. Kuçukoner, A. Dogan, Z. Oruç, Zincircioğlu Sb, E. Bodakçı, N. Akdeniz, A. Işıkdoğan","doi":"10.7727/wimj.2015.137","DOIUrl":"https://doi.org/10.7727/wimj.2015.137","url":null,"abstract":"Leukemoid reaction is characterized by an elevation in neutrophil levels in peripheral blood and is defined as a total leukocyte number exceeding 50,000/mm 3 . An increase in mature neutrophils occurs in peripheral blood in Leukemoid reaction. A 70-year-old man was referred to us due to development of leukocytosis. His history revealed that the mass had begun beneath the armpit 2 months previously and had spread rapidly. At physical examination his general condition was poor, and he was conscious, oriented and cooperative. Yellow-colored, painful, ulcerated and necrotized masses with discharge, attached to the skin and approximately 16x13 cm in size were determined in the left axilla. A painful, ulcerated, hemorrhagic mass with discharge attached to the skin and appearing to begin beneath the ear lobe, 10x9 cm in size, was determined below the ear. White cell count was 100,000 mm 3 . Ninety percent segmented neutrophils, 6% non-segmented neutrophils, 1.1% lymphocytes, 2.3% monocytes, 0.2% basophils and 0.3% eosinophils were determined at peripheral smear. Leukocyte alkaline phosphatase score was high. Squamous cell carcinoma with paraneoplastic Leukemoid reaction is an exceedingly rare combination. This case report was intended to remind physicians of the condition.","PeriodicalId":49366,"journal":{"name":"West Indian Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2018-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48622556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hearing Evaluation in Children with Type 1 Diabetes Mellitus 1型糖尿病儿童的听力评价

IF 0.1 4区医学

West Indian Medical Journal Pub Date : 2018-01-26 DOI: 10.7727/WIMJ.2017.150

Sakat, K. Kılıç, A. Çayır

引用次数: 0