Alicja Dudek, Barbara Zapała, Ilona Kawa, Karol Ciszek, Piotr Tylec, Katarzyna Cyranka, Michał Wysocki, Piotr Major
{"title":"Metabolic and bariatric surgery reduces aging biomarkers in patients with obesity, independently of achieving optimal total weight loss.","authors":"Alicja Dudek, Barbara Zapała, Ilona Kawa, Karol Ciszek, Piotr Tylec, Katarzyna Cyranka, Michał Wysocki, Piotr Major","doi":"10.20452/wiitm.2025.17946","DOIUrl":"10.20452/wiitm.2025.17946","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity, a chronic disease linked to premature aging, is increasingly managed through metabolic and bariatric surgery (MBS).</p><p><strong>Aim: </strong>This study aimed to evaluate whether changes in biological age markers depended on the optimal weight loss rates resulting from MBS.</p><p><strong>Materials and methods: </strong>In this prospective, observational study, 100 patients with obesity scheduled for MBS from July 2020 to May 2021 underwent a 24-month postoperative follow-up. The telomere length (TL) was assessed using quantitative polymerase chain reaction. We also evaluated DNA damage, C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor α (TNF-α) levels, total oxidant status (TOS), and the metabolic age. We checked whether the percentage of total body weight loss (%TWL) and the percentage excess weight loss (%EWL) correlated with the changes in aging markers postsurgery.</p><p><strong>Results: </strong>Forty patients completed follow-up, with 22 achieving optimal (%TWL ≥20%; %EWL ≥50%) and 18 suboptimal (%TWL <20%; %EWL <50%) surgical outcomes. Both groups showed a significant TL increase and a reduction of DNA damage, CRP, IL-6, and TNF-α levels, TOS, and the metabolic age. A greater change, however, was only observed for the metabolic age in the optimal outcome group. The Δ of change in the other aging markers did not differ between the groups.</p><p><strong>Conclusions: </strong>Improvements in aging markers, such as TL, DNA damage, inflammatory parameters, and TOS occur independently of weight loss rates after MBS, suggesting that weight loss indices alone do not fully capture the therapeutic success of the procedure.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 2","pages":"196-203"},"PeriodicalIF":1.9,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacek Szeliga, Mateusz Jagielski, Jacek Sobocki, Michał Borys, Mirosław Czuczwar, Adam Durczyński, Tomasz Gach, Piotr Hogendorf, Andrzej Kawiński, Katarzyna Kuśnierz, Piotr Major, Michał Mik, Michał Pędziwiatr, Paweł Piwowarczyk, Marek Sierżęga, Michał Spychalski, Wojciech Szczeklik, Mirosław Szura, Mateusz Wierdak, Witold Zgodziński, Andrzej Budzyński, Stanisław Hać, Marek Jackowski, Wojciech Kielan, Michał Kukla, Sławomir Mrowiec, Piotr Myśliwiec, Jerzy Sieńko, Maciej Słodkowski, Wiesław Tarnowski, Grzegorz Wallner, Marek Zawadzki, Krzysztof Zieniewicz
{"title":"Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.","authors":"Jacek Szeliga, Mateusz Jagielski, Jacek Sobocki, Michał Borys, Mirosław Czuczwar, Adam Durczyński, Tomasz Gach, Piotr Hogendorf, Andrzej Kawiński, Katarzyna Kuśnierz, Piotr Major, Michał Mik, Michał Pędziwiatr, Paweł Piwowarczyk, Marek Sierżęga, Michał Spychalski, Wojciech Szczeklik, Mirosław Szura, Mateusz Wierdak, Witold Zgodziński, Andrzej Budzyński, Stanisław Hać, Marek Jackowski, Wojciech Kielan, Michał Kukla, Sławomir Mrowiec, Piotr Myśliwiec, Jerzy Sieńko, Maciej Słodkowski, Wiesław Tarnowski, Grzegorz Wallner, Marek Zawadzki, Krzysztof Zieniewicz","doi":"10.20452/wiitm.2025.17941","DOIUrl":"10.20452/wiitm.2025.17941","url":null,"abstract":"","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"1-29"},"PeriodicalIF":1.7,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous endoscopic lumbar partial laminectomy assisted by a new miniature parallel surgical robot system: a trial on a cadaveric specimen.","authors":"Nan Su, Jiashen Shao, Gang Zhu, Yu Wang","doi":"10.20452/wiitm.2025.17935","DOIUrl":"10.20452/wiitm.2025.17935","url":null,"abstract":"<p><strong>Introduction: </strong>Robot‑assisted surgery is becoming increasingly popular and its application is expanding to various spinal surgical procedures, including endoscopic spinal surgery.</p><p><strong>Aim: </strong>The aim of this study was to describe a novel small parallel orthopedic surgical robot and evaluate its feasibility in assisting surgeons during percutaneous lumbar laminectomy on cadaveric specimens.</p><p><strong>Materials and methods: </strong>The authors of the study developed a new orthopedic surgical navigation system (R‑Pharos, Rossum Robot Co., Ltd, Beijing, China), consisting of a navigation cart and a hybrid serial‑parallel bedside robotic arm. The system is equipped with interactive software for selecting and planning the percutaneous lumbar laminectomy target and path. A cadaveric specimen was selected for a right‑side partial laminectomy at L4. During the procedure, the surgeon used the robotic arm to guide the saw to the target lamina and perform the percutaneous resection. Postoperative cone beam computed tomography (CBCT) and endoscopic assessments were used to confirm the resection outcome.</p><p><strong>Results: </strong>After optimizing the precision of the small parallel orthopedic surgical robot to 1 mm, it was shown to meet the navigational requirements for percutaneous lumbar laminectomy. The surgeon utilized the interactive software to design the resection range and path for the right L4 lamina which was successfully resected, as confirmed by endoscopic observation. A postoperative CBCT scan revealed that the resection area precisely matched the preoperative design.</p><p><strong>Conclusions: </strong>This study demonstrated that the small parallel orthopedic surgical robot was capable of preoperatively planning the lamina resection area and could assist the surgeon in performing percutaneous lumbar laminectomy with high navigational precision.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"99-105"},"PeriodicalIF":1.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rui Zhu, Kui Mao, Xin-Zhi Lu, You-Qing Wang, Qian-Qian Li, Zi Ye
{"title":"Transarterial chemoembolization with 125 I seed insertion for unresectable hepatocellular carcinoma: a meta‑analysis.","authors":"Rui Zhu, Kui Mao, Xin-Zhi Lu, You-Qing Wang, Qian-Qian Li, Zi Ye","doi":"10.20452/wiitm.2025.17931","DOIUrl":"10.20452/wiitm.2025.17931","url":null,"abstract":"<p><strong>Introduction: </strong>Transarterial chemoembolization (TACE) is frequently used to treat patients with hepa‑ tocellular cancer (HCC) who are not eligible for surgery. The efficacy of TACE treatment can be improved by percutaneous insertion of 125I seeds after the procedure.</p><p><strong>Aim: </strong>This meta‑analysis aimed to assess the relative safety and efficacy of TACE with 125I seed insertion (TACE‑I) as compared with TACE alone for the management of inoperable HCC.</p><p><strong>Materials and methods: </strong>The PubMed, Cochrane Library, and Wanfang databases were searched for relevant studies published since the database inception through October 2024. The primary study outcome was objective response rate (ORR), while secondary outcomes comprised disease control rate (DCR), progression‑free survival (PFS), overall survival (OS), and adverse event incidence.</p><p><strong>Results: </strong>This meta‑analysis ultimately included 5 articles, all of which were published in China. In all these studies, TACE‑I outperformed TACE alone with respect to patient ORR (P <0.001), PFS (P <0.001), and OS (P <0.001). DCR values were similar in both groups (P = 0.77), as were the rates of adverse events, including fever (P = 0.75), vomiting (P = 0.83), and myelosuppression (P = 0.23). The only outcome exhibiting significant heterogeneity was OS (I2 = 73%). Based on the Egger test, the end points affected by publication bias were ORR, DCR, and OS (P = 0.01, P = 0.03, and P = 0.04, respectively).</p><p><strong>Conclusions: </strong>In patients with inoperable HCC, TACE‑I is associated with significantly better efficacy and longer survival than TACE alone, and has a good safety profile.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"30-35"},"PeriodicalIF":1.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A retrospective cohort study comparing different fixation methods for the MiniMizer Extra adjustable gastric band.","authors":"Žygimantas Juodeikis, Gintautas Brimas","doi":"10.20452/wiitm.2025.17937","DOIUrl":"10.20452/wiitm.2025.17937","url":null,"abstract":"<p><strong>Introduction: </strong>Two decades ago, laparoscopic adjustable gastric banding was a leading bariatric sur‑ gery. However, its popularity has declined, with sleeve gastrectomy becoming the predominant choice. The MiniMizer Extra band used in our clinic from 2008 to 2020 was associated with band erosion primarily at its lower edge. In 2014, we started using a modified band fixation technique by placing sutures only on the upper part of the band.</p><p><strong>Aim: </strong>The aim of this study was to compare 2 different fixation techniques for the MiniMizer Extra adjustable gastric band to identify any potential differences in outcomes.</p><p><strong>Materials and methods: </strong>In this study, we compared 54 patients who underwent adjustable gastric banding with the MiniMizer Extra band between January 1, 2009, and January 31, 2010, with a group of 54 patients who were subjected to the procedure between January 1, 2014, and January 31, 2019, using a different band fixation method.</p><p><strong>Results: </strong>Weight loss results significantly favored the modified fixation group, with an average total weight loss of 24.2%. The overall complication rate was 12% and was significantly higher in the original fixation group. Complications included 6 cases of band erosion, 4 port‑related issues, 1 case of band slippage, and 2 cases of band intolerance.</p><p><strong>Conclusions: </strong>The modified fixation group demonstrated improved weight loss results with fewer com‑ plications, suggesting a potential advantage in safety and efficacy of the modified technique.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"51-54"},"PeriodicalIF":1.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michal Balík, Pavel Navráti, Lucie Šmejkalová, Miloš Broďák
{"title":"Robot‑assisted resection of a rare bladder tumor facilitated by perioperative bladder wall tattooing.","authors":"Michal Balík, Pavel Navráti, Lucie Šmejkalová, Miloš Broďák","doi":"10.20452/wiitm.2025.17932","DOIUrl":"10.20452/wiitm.2025.17932","url":null,"abstract":"<p><p>Inflammatory myofibroblastic tumors (IMTs) of the bladder are rare, with a limited number of cases reported in the literature. Complete resection with negative margins is essential to reduce the risk of recurrence, while bladder function preservation is also crucial for the patient. This study describes a 56‑year‑old patient with a bladder dome IMT managed using robot‑assisted partial cystectomy facili‑ tated by perioperative cystoscopic tattooing to precisely demarcate the tumor margins. The procedure began with cystoscopic tattooing of the lesion using Black Eye dye, followed by robotic resection with the da Vinci Xi system. Complete transmural resection and a 2‑layer bladder closure were performed, with preservation of the bladder capacity. The patient experienced minimal blood loss, no intraopera‑ tive complications, and was discharged 2 days after the procedure. Follow‑up examinations, including cystoscopy and computed tomography, confirmed no recurrence 12 months after surgery. Cystoscopic tattooing facilitated clear intraoperative tumor localization, enabling precise resection and minimal bladder wall loss. This approach addressed a key challenge of robotic bladder surgery-lack of tactile feedback-while maintaining functional outcomes. Robot‑assisted partial cystectomy with cystoscopic tattooing represents a promising alternative to maximal transurethral resection, especially in the context of bladder‑sparing trimodal therapy, for patients who are not eligible for or unwilling to undergo radical cystectomy. This technique is particularly relevant given the increasing focus on minimally invasive procedures and advancements in systemic therapy. In the future, this method could be adapted for ureteral robotic surgeries to enhance lesion localization.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"114-117"},"PeriodicalIF":1.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafał B Drobot, Marcin Lipa, Jędrzej J Skorupka, Artur A Antoniewicz
{"title":"Robot‑assisted surgical management of mid‑urethral sling erosion into the bladder using transperitoneal robotic extensive approach for total mesh excision.","authors":"Rafał B Drobot, Marcin Lipa, Jędrzej J Skorupka, Artur A Antoniewicz","doi":"10.20452/wiitm.2024.17939","DOIUrl":"10.20452/wiitm.2024.17939","url":null,"abstract":"<p><p>Robot‑assisted surgical management of mid‑urethral sling (MUS) erosion into the bladder represents a novel approach in urological surgery. This study reports the first 2 cases in Poland treated using the transperitoneal robotic extensive approach for total mesh excision (TREATME). Both procedures were performed successfully, with complete mesh removal. No intra‑ or postoperative complications occurred, and conversion to open surgery was not required. These initial findings suggest that TREATME may be a feasible and safe option for managing complex MUS complications, necessitating further evaluation in larger studies.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"118-123"},"PeriodicalIF":1.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jakub Erdmann, Maria Zabrzyńska, Przemysław Pękala, Szymon Nowak, Filip Gołębiewski, Gazi Huri, Jan Zabrzyński
{"title":"Functional outcomes of simultaneous anterior cruciate ligament reconstruction and lateral extra-articular tenodesis using an all-suture anchor: a modified mini-open technique.","authors":"Jakub Erdmann, Maria Zabrzyńska, Przemysław Pękala, Szymon Nowak, Filip Gołębiewski, Gazi Huri, Jan Zabrzyński","doi":"10.20452/wiitm.2025.17938","DOIUrl":"10.20452/wiitm.2025.17938","url":null,"abstract":"<p><strong>Introduction: </strong>The anterior cruciate ligament (ACL) rupture frequently leads to instability of the knee joint, which subsequently damages other intra‑articular structures. The combination of ACL reconstruction (ACLR) with concurrent lateral extra‑articular tenodesis (LET) improves rotational stability and reduces the risk of subsequent ACL rupture. However, there is not much research that specifically outlines LET hardware and surgical methods.</p><p><strong>Aim: </strong>This study aimed to describe and evaluate clinical outcomes of a mini‑open modified Lemaire technique using a self‑punching all‑suture anchor.</p><p><strong>Materials and methods: </strong>In this study, 32 patients underwent primary or revision ACLR combined with LET via the mini‑open modified Lemaire technique using a self‑punching all‑suture anchor. All individuals completed the following pre‑ and postoperative questionnaires to evaluate their functional performance: the Knee Injury and Osteoarthritis Outcome Score, assessing several domains, the International Knee Documentation Committee subjective knee evaluation form, the Lysholm knee scoring scale, and the Western Ontario and McMaster Universities Arthritis Index. Complication rates were also assessed.</p><p><strong>Results: </strong>Each patient's functional score values increased, as compared with preoperative measure‑ ments. There were no early post‑ or intraoperative complications associated with the technique described.</p><p><strong>Conclusions: </strong>This is the first study that evaluated clinical outcomes, intraoperative, and early post‑ operative complications of the mini‑open modified Lemaire technique using a self‑punching all‑suture anchor. Our study indicates that this procedure is effective, safe, and associated with better cosmesis than classic LET techniques.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"76-83"},"PeriodicalIF":1.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Barnaś, Tomasz Milecki, Agnieszka Ida, Michał Kasperczak, Adam Lipski, Andrzej Antczak, Wojciech A Cieślikowski
{"title":"Learning curve for laparoscopic radical prostatectomy.","authors":"Anna Barnaś, Tomasz Milecki, Agnieszka Ida, Michał Kasperczak, Adam Lipski, Andrzej Antczak, Wojciech A Cieślikowski","doi":"10.20452/wiitm.2025.17933","DOIUrl":"10.20452/wiitm.2025.17933","url":null,"abstract":"<p><strong>Introduction: </strong>While robotic prostatectomies are gaining popularity, laparoscopic and open surgeries remain prevalent in Central and Eastern Europe due to their cost‑effectiveness. In Poland, many urology residents report insufficient laparoscopic training. This study retrospectively evaluated the learning curve for laparoscopic radical prostatectomy (LRP).</p><p><strong>Aim: </strong>This paper aimed to assess the learning curve of a single resident performing extraperitoneal LRP.</p><p><strong>Materials and methods: </strong>We analyzed 72 patients who underwent LRP between 2016 and 2020 at a single center, divided into 5 groups (G1-G5) according to chronological order. The procedures were per‑ formed by a single urologist without on‑site supervision. Outcomes included operative duration, length of hospital stay, complications, transfusion rates, histopathology findings, biochemical recurrence, and urinary incontinence.</p><p><strong>Results: </strong>Patient characteristics were similar across all groups. The median (interquartile range [IQR]) age ranged from 61 (54-66) to 68 (66-70) years, and the median (IQR) prostate‑specific antigen con‑ centration, from 6.7 (5.4-8.5) to 15 (6.3-19.3) ng/ml. Higher Gleason scores were more common in the G3 and G4 groups (P = 0.05) than in the other groups. Surgery time decreased from 183 minutes in the G1 group to 130 minutes in the G5 group (P <0.001). The rates of positive surgical margins were the highest in the G3 and G4 groups (53.3% and 46.7%, respectively; P = 0.02). The rate of urinary continence improved from 66.7% in the G1 group to 86.7% in the G4 group (P = 0.36); however, without any significant difference among all groups. Biochemical recurrence rates tended to be lower in the G4 and G5 groups (6.7% and 8.3%, respectively), but the difference across all groups was nonsignificant. Grade III-V complications occurred only in the G1 group.</p><p><strong>Conclusions: </strong>Surgical outcomes improved after 15 procedures, and the oncological outcomes, after 45, with functional improvement observed later. Performing hundreds of surgeries may be required to achieve high proficiency in performing LRP.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"69-75"},"PeriodicalIF":1.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of sex on the outcomes of uniportal video‑assisted thoracoscopic sympathicotomy for primary palmar hyperhidrosis.","authors":"Turkan Dubus, Gokce Cangel, Fatih Kesmezacar","doi":"10.20452/wiitm.2025.17934","DOIUrl":"10.20452/wiitm.2025.17934","url":null,"abstract":"<p><strong>Introduction: </strong>Primary palmar hyperhidrosis (PPH) impairs the quality of life. Video‑assisted thoracoscopic sympathicotomy is an effective treatment method; however, the impact of sex on surgical outcomes accord‑ ing to the denervation level (T3 vs T3-T4 sympathicotomy) remains unclear.AIM This study investigated the efficacy, complications, and symptom relief rates of isolated T3 vs combined T3-T4 sympathicotomy for PPH, focusing on sex differences.</p><p><strong>Materials and methods: </strong>A retrospective analysis of 327 patients undergoing bilateral uniportal video‑assisted thoracoscopic sympathicotomy for PPH between 2012 and 2022 was performed. The patients were divided into 2 groups depending on the procedure type (isolated T3 sympathicotomy [n = 167] vs T3-T4 combined sympathicotomy [n = 160]). Demographic data, procedure outcomes, and complications were compared.</p><p><strong>Results: </strong>Success rates were 95.8% in the T3 sympathicotomy group and 93.8% in the T3-T4 sympathicotomy group, with no significant difference. The most common complication was dryness of the hands. The overall complication rate was lower in the T3 than in the T3-T4 sympathicotomy group (9.6% vs 14.4%; P = 0.04). Compensatory sweating occurred in 2.4% and 3.1% of the participants in the T3 and T3-T4 sympathicotomy groups, respectively (P = 0.52). The frequency of compensatory sweating, chest pain, and dryness of the hands was significantly higher in men. Age, sex, and duration of surgery had no independent influence on the occurrence of complications.</p><p><strong>Conclusions: </strong>Isolated T3 sympathicotomy is an effective and safe option for the treatment of PPH, and is associated with fewer complications than combined T3-T4 sympathicotomy. Higher complication rates in men emphasize the need for sex‑specific surgical planning and patient counseling.</p>","PeriodicalId":49361,"journal":{"name":"Videosurgery and Other Miniinvasive Techniques","volume":"20 1","pages":"55-60"},"PeriodicalIF":1.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}