Wspolczesna Onkologia-Contemporary Oncology最新文献_第10页

M-TOR inhibitors in the treatment of advanced renal cell carcinoma M-TOR抑制剂治疗晚期肾细胞癌

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26432

R. Stec, M. Mączewski, M. Smoter, L. Bodnar, C. Szczylik

引用次数: 0

What is the alternative to persistent therapy? The English proposal for standardized procedures applied in the last hours of the oncological patient’s life 持续治疗的替代方案是什么?在肿瘤病人生命的最后几个小时应用标准化程序的英文建议

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26435

Justyna Bochenek, Mirosława Püsküllüoğlu, A. Stochel-Gaudyn

引用次数: 1

Extragonadal form of germ cell pineal tumour: a case report 性腺外型生殖细胞松果体肿瘤1例

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26443

M. Chilimoniuk, E. Olszewska, A. Kiluk

{"title":"Extragonadal form of germ cell pineal tumour: a case report","authors":"M. Chilimoniuk, E. Olszewska, A. Kiluk","doi":"10.5114/WO.2011.26443","DOIUrl":"https://doi.org/10.5114/WO.2011.26443","url":null,"abstract":"The pineal region is the most common area for germ cell tumours. They are mostly observed in children. In adults they are more common in men in the second or third decade of life. Pineal tu mours have a diverse histopathology. Their growth is slow and the symptoms result from the compression of adjacent cerebral structures. One of the histopathological forms is germinal tumours, including mild or malignant teratoma. They have the ability to release neoplastic markers, e.g. AFP, β-HCG, which are used to evaluate the effectiveness of surgical and oncological treatment. The paper presents a case of a 24-year-old man di agnosed as teratocarcinoma. The treat ment protocol consisted of both surgery and conventional fractionation radio therapy (Df = 1.8 Gy, 5 ◊ weekly) to the total dose of 50.4 Gy. After a few months, there was a recurrence of the cancer process. The patient received 2 courses of chemotherapy, which did not yield the expected therapeutic effect. The patient’s prognosis is unfavourable due to rapid local relapse and failure after treatment. The case is presented due to the rarity of pineal teratocarcinoma tu mours and the age of the patient.","PeriodicalId":49354,"journal":{"name":"Wspolczesna Onkologia-Contemporary Oncology","volume":"47 1","pages":"399-403"},"PeriodicalIF":1.8,"publicationDate":"2011-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74096190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of patient referrals to the outpatient haematology clinic in Elbląg Elbląg血液科门诊病人转诊分析

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26442

J. Zaucha, K. Adamowicz, M. Zalewska, A. Zabłocka, Joanna Adamowicz, A. Mital

{"title":"Analysis of patient referrals to the outpatient haematology clinic in Elbląg","authors":"J. Zaucha, K. Adamowicz, M. Zalewska, A. Zabłocka, Joanna Adamowicz, A. Mital","doi":"10.5114/WO.2011.26442","DOIUrl":"https://doi.org/10.5114/WO.2011.26442","url":null,"abstract":"sultation in Poland ranges from a couple to several dozen weeks. This is due to the shortage of haematology specialists, their uneven distribution and lack of clear rules regarding patient referrals to outpatient haematology clinics (OHCs). Complete blood count (CBC) is a cheap and widely performed laboratory test. However, in view of problems frequently encountered by primary care physicians with proper interpretation of CBC results, particularly with the differential diagnosis of malignant blood diseases from benign or reactive abnormalities, we hypothesized that the main reason for referring patients to OHCs might be any CBC deviation. To test this hypothesis, we analysed the structure of patient referrals to the OHC in Elbląg. Additionally, we sought to establish guidelines for primary care physicians to follow while referring patients identified with CBC abnormalities for haematology assessment. The study analyses the reasons for 986 patient referrals to the OHC in Elblag (in 2005-2009). Referrals due to CBC abnormalities were also evaluated to determine their severity. Most of the patients (690) referred to the OHC were female (70%). The most common reason for OHC referral, identified in 33% of patients with CBC abnormalities, was anaemia, followed by thrombocytopenia (25%) and leucopenia (16%). The severity of CBC abnormalities was mild in the majority of patients. At the time of their first OHC visit, only 60% of anaemia and thrombocytopenia cases in fact met the criteria for the respective diagnosis, which indicates that the abnormalities resolved spontaneously and could have been monitored by the primary care physician. Based on the above results and own experience, the authors have proposed practical guidelines on referral indications in the case of CBC abnormalities. The guidelines, coupled with the expansion of knowledge of haematological diseases among primary care physicians, might contribute to reducing the number of patients referred for haematology assessment.","PeriodicalId":49354,"journal":{"name":"Wspolczesna Onkologia-Contemporary Oncology","volume":"48 1","pages":"391-398"},"PeriodicalIF":1.8,"publicationDate":"2011-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82368034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Assessment of intraoperative and postoperative complications during implementation of laparoscopic radical prostatectomy in patients with locally advanced prostate cancer 局部晚期前列腺癌腹腔镜根治性前列腺切除术术中及术后并发症的评价

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26439

P. Cieśliński, Małgorzata Hojan-Osicka, A. Antczak, Z. Kwias

{"title":"Assessment of intraoperative and postoperative complications during implementation of laparoscopic radical prostatectomy in patients with locally advanced prostate cancer","authors":"P. Cieśliński, Małgorzata Hojan-Osicka, A. Antczak, Z. Kwias","doi":"10.5114/WO.2011.26439","DOIUrl":"https://doi.org/10.5114/WO.2011.26439","url":null,"abstract":"personal experience in performing laparoscopic radical prostatectomy (LRP) at our institution. Material and methods: Within less than two years, i.e. from November 2008 to August 2010, 30 laparoscopic radical prostatectomies were performed at the Department of Urology and Uro-Oncology in Poznań. The operations were performed with the retroperitoneal approach. Lymphadenectomy was performed only in the patients with a preoperative prostate specific antigen (PSA) level greater than 10 ng/ml and/or Gleason score 7 or greater. Results: The operating time ranged from 150 to 360 minutes (mean operating time was 234 minutes). Two cases required conversion to open surgery because of highly increased prostate volume (100 ml) and due to difficult operating conditions. During one of the very first procedures rectal injury occurred and the patient developed a rectourethral fistula two weeks after surgery. Six patients had a prolonged drain leakage (> 7 days) caused by dehiscence of the vesicourethral anastomosis. One patient developed a large abdominal wall haematoma in the right and left lumbar region which was successfully treated with conservative management. One patient presented haematuria which stopped spontaneously on the 10th postoperative day. On the first post-operative days 5 patients developed a fever which lasted a few days. Conclusions: An increasing number of urology clinics and hospitals perform laparoscopic radical prostatectomy. This ablative and reconstructive surgery is a technically challenging procedure and can be successfully performed by a urological team experienced in laparoscopy and radical prostatectomy. The procedure requires consistent improvement of the operative technique in order to provide patients with the most satisfactory oncological and functional results. The complication rate for all 30 patients undergoing the operation was low and complications were more frequent in initial cases.","PeriodicalId":49354,"journal":{"name":"Wspolczesna Onkologia-Contemporary Oncology","volume":"43 1","pages":"378-381"},"PeriodicalIF":1.8,"publicationDate":"2011-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88043504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Prevention of lymphoedema 预防淋巴水肿

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26434

Katarzyna Ochalek

引用次数: 6

Langerhans cell histiocytosis – the role of radiation therapy 朗格汉斯细胞组织细胞增多症-放射治疗的作用

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26433

E. Ziółkowska, Tomasz Wiśniewski, Katarzyna Indrak-Rawicka, W. Windorbska

引用次数: 0

Lanreotide therapy in a case of thymic neuroendocrine carcinoma associated with syndrome of inappropriate antidiuretic hormone secretion Lanreotide治疗胸腺神经内分泌癌伴抗利尿激素分泌不当综合征1例

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-12-28 DOI: 10.5114/WO.2011.26447

P. Gut, Jakub Fischbach, D. Baszko-Błaszyk, M. Fichna, M. Gryczyńska, M. Ruchała

{"title":"Lanreotide therapy in a case of thymic neuroendocrine carcinoma associated with syndrome of inappropriate antidiuretic hormone secretion","authors":"P. Gut, Jakub Fischbach, D. Baszko-Błaszyk, M. Fichna, M. Gryczyńska, M. Ruchała","doi":"10.5114/WO.2011.26447","DOIUrl":"https://doi.org/10.5114/WO.2011.26447","url":null,"abstract":"Neuroendocrine tumours of the thy mus are rare neoplasms, which account for 2-4% of all anterior mediastinal tu mours. Several endocrinopathies were found to be associated with these tu mours, with ectopic ACTH secretion re ported most frequently. Here we provide a description of the syndrome of inap propriate antidiuretic hormone secretion (SIADH) accompanying neuroendocrine thymic carcinoma. A mediastinal tumour was incidentally found on routine chest X-ray examina tion in a 55-year-old man. After detailed imaging studies, tumour excision was performed. The mediastinal tumour (11 ◊ 8 ◊ 4 cm) presented features of in vasion to the left lung and pericardium. Histopathological examination con firmed the diagnosis of thymic neu roendocrine carcinoma. The patient was treated with chemotherapy because of the recurrence. Symptoms of carcinoid syndrome and positive result of the so matostatin receptor scintigraphy justi fied subsequent introduction of so matostatin analogue therapy. At this point low serum sodium levels accom panied by decreased serum osmolarity and inadequate urine concentration were found. Having excluded other typ ical causes, SIADH syndrome due to ec topic vasopressin synthesis was as sumed. This finding adds to differential diagnosis of hyponatraemia, indicating that SIADH may also accompany thymic neuroendocrine tumours.","PeriodicalId":49354,"journal":{"name":"Wspolczesna Onkologia-Contemporary Oncology","volume":"140 1","pages":"407-410"},"PeriodicalIF":1.8,"publicationDate":"2011-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85373327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological and clinical significance of BRCA2 BRCA2的生物学和临床意义

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-11-22 DOI: 10.5114/WO.2011.25660

Małgorzata J Michalak, A. Filip, B. Karczmarek-Borowska, J. Wojcierowski, S. Zmorzyński

引用次数: 5

Clinical study on magnesium, copper and chrome levels in patients with oesophageal squamous cell carcinoma 食管鳞状细胞癌患者镁、铜、铬水平的临床研究

IF 1.8

Wspolczesna Onkologia-Contemporary Oncology Pub Date : 2011-11-22 DOI: 10.5114/WO.2011.25652

Zhi-Gang Sun, G. Song, Min Zhang, Zhou Wang, Z. Ni

{"title":"Clinical study on magnesium, copper and chrome levels in patients with oesophageal squamous cell carcinoma","authors":"Zhi-Gang Sun, G. Song, Min Zhang, Zhou Wang, Z. Ni","doi":"10.5114/WO.2011.25652","DOIUrl":"https://doi.org/10.5114/WO.2011.25652","url":null,"abstract":"Background: Oesophageal squamous cell carcinoma is one of the most common malignancies in China. The association of trace elements and high cancer risk has been found in many studies. The present study was performed to investigate the relationship between the concentration of magnesium, copper and chrome and the incidence and prognosis of oesophageal squamous cell carcinoma. Material and methods: The study was conducted on 36 patients with oesophageal squamous cell carcinoma and all patients underwent oesophagectomy. The cancerous tissue samples and the normal tissue samples came from the patients. The concentration of magnesium, copper and chrome was measured by flame atomic absorption spectroscopy and comparison was made using Student’s t-test. Results: The content of magnesium in cancerous tissues was significantly lower than that in the normal tissues. In contrast, copper level in cancerous tissues was significantly higher than that in the normal tissues. Copper level in patients with lymph node metastasis was significantly higher than in patients without lymph node metastasis. There was a significant increase in mean copper in cancerous tissues with a worse histological grade. Our study showed that a lower magnesium level and a higher copper level may play an important role in oesophageal squamous cell carcinoma induction. And the chrome level may not be associated with the induction of oesophageal squamous cell carcinoma.","PeriodicalId":49354,"journal":{"name":"Wspolczesna Onkologia-Contemporary Oncology","volume":"56 219 1","pages":"257-260"},"PeriodicalIF":1.8,"publicationDate":"2011-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83291063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3