Experimental and Applied Biomedical Research (EABR)最新文献

Antioxidative Activity of Some S-Alkyl Derivatives of Thiosalicylic Acid. In Vivo and In Silico Approach 硫代水杨酸某些 S-烷基衍生物的抗氧化活性。体内和硅学方法

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-07-26 DOI: 10.2478/sjecr-2024-0008

Marina Nikolic, Marina Ž. Vesović, M. Andjic, Jovana V Bradic, Aleksandar Kocovic, Nikola Nedeljković, Ana S. Živanović, Andriana M Bukonjić, D. Tomović, Gordana P Radić, Zoran Ratković, Miloš Nikolić

{"title":"Antioxidative Activity of Some S-Alkyl Derivatives of Thiosalicylic Acid. In Vivo and In Silico Approach","authors":"Marina Nikolic, Marina Ž. Vesović, M. Andjic, Jovana V Bradic, Aleksandar Kocovic, Nikola Nedeljković, Ana S. Živanović, Andriana M Bukonjić, D. Tomović, Gordana P Radić, Zoran Ratković, Miloš Nikolić","doi":"10.2478/sjecr-2024-0008","DOIUrl":"https://doi.org/10.2478/sjecr-2024-0008","url":null,"abstract":"\u0000 This study examined the effects of S-alkyl derivatives acute administration on local redox status and interaction between tested compounds and antioxidant enzymes via molecular docking studies. This study included 88 male Wistar albino rats divided into three experimental groups, receiving different S-alkyl derivatives per os in three different doses (10 mg/kg, 15 mg/kg, and 20 mg/kg) and two control groups, CMC - rats treated with 1% carboxymethyl cellulose and indomethacin group (IND) – rats treated with indomethacin (10 mg/kg). Carrageenan-induced paw edema model was used for evaluation of local antioxidant potential of the investigated S-alkyl derivatives. After finishing the experimental protocol, carrageenan-induced edema feet of each animal were collected and homogenized. From isolated supernatant pro-oxidative parameters (O2\u0000 −., NO2\u0000 −, and TBARS) and antioxidant enzymes activity (SOD, CAT, and GSH) were spectrophotometrically measured. Molecular docking studies were performed in AutoDock Vina software. The levels of pro-oxidative parameters were significantly decreased in tissue of rats treated with S-alkyl derivatives, while dose dependent manner in TBARS reduction was observed in L3 groups (p<0.05). Moreover, tested compounds exposed antioxidant activity due to enhanced CAT activity compared to untreated rats while the most prominent changes in GSH activity was observed after acute administration of L3 in the highest dose (p<0.05). According to molecular docking parameters, derivative L3 exhibited the highest binding affinity towards antioxidant enzymes. Obtained in vivo and in silico results suggest the high antioxidative potential of L3 and its beneficial effect on redox balance recovery in state of increased inflammation.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":"48 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141798722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental Animal Models of Periodontal Diseases 牙周病实验动物模型

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-05-01 DOI: 10.2478/sjecr-2021-0019

Milica Velickovic, Aleksandar Acović, A. Arsenijevic, Jelena Milovanović, Mia Rakic, Marija Milovanović, T. Kanjevac, Dragana Arsenijević

引用次数: 0

The Association of Anxiety and Depression with the Quality of Life of People with Multiple Sclerosis 焦虑和抑郁与多发性硬化症患者生活质量的关系

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-04-19 DOI: 10.2478/sjecr-2021-0076

Goran Nedovic, Ivana Sretenović, Milosav Adamović, Milica Lero, Vladimir Simic

{"title":"The Association of Anxiety and Depression with the Quality of Life of People with Multiple Sclerosis","authors":"Goran Nedovic, Ivana Sretenović, Milosav Adamović, Milica Lero, Vladimir Simic","doi":"10.2478/sjecr-2021-0076","DOIUrl":"https://doi.org/10.2478/sjecr-2021-0076","url":null,"abstract":"\u0000 The quality of life of people with multiple sclerosis is not only influenced by factors that lead to neurological disability or factors from the spectrum of a person’s demographic characteristics, but also by various mental and psychological factors that lead to altered states of these people. The aim of the research was to determine the correlation of anxiety and depression with the quality of life of people with multiple sclerosis. The sample consisted of 100 participants with multiple sclerosis (40% male, average age 47.8). The instruments used in the research included: The Beck Depression Inventory, The State-Trait Anxiety Inventory and Multiple Sclerosis Quality of Life Instrument. 75% of our participants showed significant symptoms of state anxiety, and 71% of them showed significant symptoms of trait anxiety. At the same time 59% had minimal depression and 7% had severe depression. A negative correlation was found between state anxiety and physical health (r = -0.609, p < 0.01), trait anxiety and physical health (r = -0.757, p < 0.01), state anxiety and the mental health (r = - 0.639; p < 0.01), trait anxiety and mental health (r = -0.819, p < 0.01), as well as depression and physical health (r = - 0.670, p <0.01) and depression and mental health (r = - 0.750, p <0.01). Depression and anxiety correlate negatively with quality of life and require psychosocial and social support planning programs in rehabilitation of people with multiple sclerosis.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140684613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developement and Stability Evaluation of Natural Topical Formulations Containing Pinus sibirica Essential Oil 含西伯利亚红松精油的天然外用制剂的开发和稳定性评估

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-04-06 DOI: 10.2478/eabr-2024-0003

B. Petrović, Jovana V Bradic, A. Petrović, Dragana Ivanović, Marija Tabakovic, Svetlana Saric, V. Jakovljević

{"title":"Developement and Stability Evaluation of Natural Topical Formulations Containing Pinus sibirica Essential Oil","authors":"B. Petrović, Jovana V Bradic, A. Petrović, Dragana Ivanović, Marija Tabakovic, Svetlana Saric, V. Jakovljević","doi":"10.2478/eabr-2024-0003","DOIUrl":"https://doi.org/10.2478/eabr-2024-0003","url":null,"abstract":"\u0000 Pinus sibirica (P. sibirica) is used in folk medicine for centuries in treatment of various diseases due to its anti-inflammatory, antioxidant, and antimicrobial activity. The present study was focused on formulating semi-solid topical cream and gel preparations with P. sibirica essential oil (EOPS) and on evaluation of their stability during three months of storage. After preparation of semi-solid formulations (cream and gel), we followed parameters such as organoleptic characteristics, pH values, electrical conductivity, phase separation, washability, swelling index and microbiological contamination. Tests for physical and microbiological stability were performed considering different storage conditions at temperature (4±2° C, 25±2°C and 40±2°C) for 12 weeks. All test were performed at sampling time points of 7th, 30th, 60th, 90th day after storage. Cream with EOPS was white colour, it is homogenous with pleasant odor characteristic to used EOPS while gel with EOPS was transparent, it is homogenous with specific odor. After application to skin, EOPS cream was leaving non-greasy film while gel with EOPS was leaving sticky film and cooling effect. In all tested samples, we observed no phase separation and pH values were optimal for skin application. During three months of storage at different conditions, all tested formulations were stable and addition of EOPS did not cause any changes in followed parameters. Both cream and gel formulation remained stable since we did not notice any significant changes in all followed parameters during storage at different temperatures. Addition of 0.5% of EOPS did not change visual, sensory and microbial properties of formulations.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":"35 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140735201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Implications of Actovegin® in Sport: A Brief Review Actovegin® 在体育运动中的意义：简要回顾

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-03-23 DOI: 10.2478/eabr-2023-0014

Dragana Milovanovic, Emilija Stojanovic

{"title":"The Implications of Actovegin® in Sport: A Brief Review","authors":"Dragana Milovanovic, Emilija Stojanovic","doi":"10.2478/eabr-2023-0014","DOIUrl":"https://doi.org/10.2478/eabr-2023-0014","url":null,"abstract":"\u0000 Actovegin® (or Solcoseryl) is a deproteinized hemoderivative of calf’s blood, which contains more than 200 bioactive constituents. Screening and identification of biologically active molecule(s) is challenging due to the complexity of many constituents that may influence various cellular biochemical pathways and are found naturally in the body. Actovegin® comes in different forms including cream, gel, ointment, tablets, and injectable solution. Currently, according to section M2, Chemical and Physical Manipulation of the World Anti-Doping Code, intravenous injections of Actovegin® exceeding 100 ml is prohibited and further serial injections must be at least 12 hours apart. Although the performance-enhancing effects of Actovegin® are still anecdotal, the use of this drug has undoubtedly been widespread in sports for more than two decades. Existing findings provide promising results regarding the effect of Actovegin® in treating muscle injuries at the injected site. Further research exploring other forms of Actovegin ® (tablets, gel, cream) is encouraged to better understand the potential benefits of Actovegin® in applied sports settings.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":" 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140211182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxidative Stress and Thrombophilia: Focus on Pregnancy-Related Pathophysiological Mechanisms 氧化应激与血栓性疾病：关注与妊娠有关的病理生理机制

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-03-01 DOI: 10.2478/eabr-2023-0010

A. Dimitrijevic, V. Jakovljevic, N. Jovic, J. Djuric, K. Andric, J. J. Jovic

{"title":"Oxidative Stress and Thrombophilia: Focus on Pregnancy-Related Pathophysiological Mechanisms","authors":"A. Dimitrijevic, V. Jakovljevic, N. Jovic, J. Djuric, K. Andric, J. J. Jovic","doi":"10.2478/eabr-2023-0010","DOIUrl":"https://doi.org/10.2478/eabr-2023-0010","url":null,"abstract":"\u0000 Thrombophilia, characterized by an increased tendency to form blood clots, presents a substantial risk during pregnancy, potentially impacting maternal and fetal outcomes. This review explores the intricate relationship between thrombophilia and oxidative stress, shedding light on their combined influence on blood clot formation. Specifically, endothelial dysfunction, driven by oxidative stress, emerges as a pivotal factor in thrombophilia, setting the stage for increased platelet activation and altered coagulation factors. Factors like Factor V Leiden mutation, Prothrombin G20210A mutation, and deficiencies in antithrombin, protein C, and protein S contribute to the pro-thrombotic state observed in thrombophilia. Furthermore, inflammation, closely intertwined with oxidative stress, exacerbates the risk of blood clot formation. Inflammatory responses lead to endothelial activation, altered endothelial function, and increased adhesion molecules expression, disrupting the delicate balance between pro- and anti-coagulant factors. Chronic inflammatory conditions, such as autoimmune disorders, potentiate a persistent state of heightened clotting risk. Additionally, impaired antioxidant defenses compound the prothrombotic state by allowing the accumulation of reactive oxygen species, thereby contributing to oxidative stress-induced endothelial dysfunction. Understanding the interplay between these factors is crucial for tailored thrombophilia management, particularly in pregnancy. Treatment strategies encompass a multifaceted approach, including anticoagulant medications, lifestyle modifications, and targeted interventions to improve endothelial health. The complex nature of thrombophilia underscores the need for a collaborative healthcare approach, involving hematologists and high-risk pregnancy specialists. Early detection, vigilant monitoring, and timely intervention are paramount in mitigating risks for both mother and baby.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140271207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Perceived Assessment of Covid-19 Impact on Mental Functioning and Suicidality in Adult Population of Serbia 塞尔维亚成年人对 Covid-19 对心理功能和自杀倾向影响的认知评估

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-03-01 DOI: 10.2478/eabr-2024-0001

Mladenović Milena, Deniz Ceylan, Marković Dušan, Olivera Radmanović

{"title":"The Perceived Assessment of Covid-19 Impact on Mental Functioning and Suicidality in Adult Population of Serbia","authors":"Mladenović Milena, Deniz Ceylan, Marković Dušan, Olivera Radmanović","doi":"10.2478/eabr-2024-0001","DOIUrl":"https://doi.org/10.2478/eabr-2024-0001","url":null,"abstract":"\u0000 The aim of the study was to determine the extent to which people in Serbia in the post-pandemic period assess the impact of coronavirus pandemic on their mental/professional functioning, and whether this assessment is correlated with the occurrence of suicidal ideation and behaviours. The retrospective-prospective study was conducted online via Google Forms during January 2023. The sample included 341 respondents from the general population, 250 women (73.3%) and 91 men (26.7%), aged from 19 to 72 (M=36.41, SD=14.72). Sociodemographic questionnaire, a questionnaire on the pandemic effects, and the Risk Assessment Suicidality Scale were used to obtain data. The respondents assessed the pandemic not to have exerted a significant effect on their mental life (M=1.19±0.84) and professional functioning (M=1.55±1.02). The women, university students, pensioners and single respondents reported a greater impact of the pandemic on mental functioning, while university students and single respondents reported a greater impact on professional functioning. The respondents who were assessed to be at suicide risk (15.8%) reported a higher effect of the pandemic on mental (U=5385, p<0.001) and professional functioning (U=5799, p<0.01). Multivariant binary logistic regression showed that having a family history of mental disorders (odds ratio 2.73), younger age (OR, 1.1) and not being in a relationship (OR, 0.49) increased suicide risk in this sample. Results are in line with previous findings indicating that women, university students and pensioners reported a higher effect of the pandemic on the level of stress, depression and anxiety symptoms. The study also speaks in favour of a specific vulnerability of people suffering from mental difficulties after the pandemic.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":"34 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140082690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations Between Metabolic Syndrome, Ulcerative Colitis, and Fecal sST2 and CXCL8 Levels: Unveiling New Inflammatory Pathways 代谢综合征、溃疡性结肠炎与粪便 sST2 和 CXCL8 水平之间的关系：揭示新的炎症途径

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-01-24 DOI: 10.2478/sjecr-2023-0013

Samir Vucelj, Irfan Corovic, Marina Z Jovanovic, Andjela Petrović, Isidora Stanisavljević, Bojan Stojanović, Kemal Corovic, Ivana Andrejevic, N. Zdravković, Milica Dimitrijevic Stojanovic, Goran Balovic, Bojan Stojanović

{"title":"Associations Between Metabolic Syndrome, Ulcerative Colitis, and Fecal sST2 and CXCL8 Levels: Unveiling New Inflammatory Pathways","authors":"Samir Vucelj, Irfan Corovic, Marina Z Jovanovic, Andjela Petrović, Isidora Stanisavljević, Bojan Stojanović, Kemal Corovic, Ivana Andrejevic, N. Zdravković, Milica Dimitrijevic Stojanovic, Goran Balovic, Bojan Stojanović","doi":"10.2478/sjecr-2023-0013","DOIUrl":"https://doi.org/10.2478/sjecr-2023-0013","url":null,"abstract":"\u0000 Ulcerative Colitis (UC), a chronic inflammatory bowel disease, exhibits complex interactions with metabolic disorders such as Metabolic Syndrome (MetS), which can significantly impact disease progression and patient outcomes. Among the multitude of players in this intricate network, soluble ST2 (sST2) and Chemokine (C-X-C motif) ligand 8 (CXCL8) have emerged as critical mediators of immune responses, potentially modulating the disease course in UC patients with co-existing MetS. This study aimed to investigate the association between Metabolic Syndrome (MetS) and immune response modulation in patients with Ulcerative Colitis (UC). UC patients, stratified by the presence of MetS, underwent clinical, endoscopic, and histological evaluation, along with blood and fecal biochemical analyses. Serum and fecal concentrations of sST2 and CXCL8 were measured and compared between groups. UC patients with MetS exhibited lower white blood cell (WBC) count, higher levels of metabolic markers, and milder disease severity on clinical, endoscopic, and histological scales. Serum concentrations of sST2 and CXCL8 were similar between UC patients with and without MetS. However, fecal levels of these cytokines were significantly elevated in UC patients with MetS, suggesting a localized intensified immune response. Our findings indicate a potential dichotomy in the immune response of UC patients with MetS, characterized by a dampened systemic inflammation and heightened local immune response. The elevated fecal levels of sST2 and CXCL8 underscore a potentially unique immune modulation within the gut in the presence of MetS. These findings shed new light on the pathophysiological interplay between MetS and UC and may provide new avenues for targeted therapeutic strategies.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139599053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic Value of Prostata Specific Antigen and Digital Rectal Examination at Prostate Biopsy 前列腺活检时前列腺特异抗原和数字直肠指检的预后价值

Experimental and Applied Biomedical Research (EABR) Pub Date : 2024-01-24 DOI: 10.2478/sjecr-2023-0011

Filip Milutinović, Djordje Djordjevic, Djordje Todorovic, Dusan Zaric, Filip Mihajlovic

{"title":"Prognostic Value of Prostata Specific Antigen and Digital Rectal Examination at Prostate Biopsy","authors":"Filip Milutinović, Djordje Djordjevic, Djordje Todorovic, Dusan Zaric, Filip Mihajlovic","doi":"10.2478/sjecr-2023-0011","DOIUrl":"https://doi.org/10.2478/sjecr-2023-0011","url":null,"abstract":"\u0000 Prostate cancer is a worldwide health concern with an increasing global incidence. In the Republic of Serbia, it is the third most commonly diagnosed cancer in men. The research aims to determine the influence of PSA value and digital rectal examination on the pathohistological findings of prostate biopsy in men in Central Serbia. The study was designed as a retrospective, cross-sectional analytical study conducted in the period from December 2021 to December 2022 after receiving the confirmation of the Ethics Committee of the University of Applied Sciences Kragujevac. Among 151 respondents aged 49 to 88 who underwent consecutive biopsies during the study period, prostate cancer was detected in 65 (42%). Out of 65 positive biopsies, 33 subjects had a Gleason score of up to 7, while 32 subjects had a Gleason score over 7. Prostate biopsies significantly correlated with PSA levels (p=0.02), while DRE and prostate volume did not show statistical significance on the prostate biopsy result. PSA level testing leads to early detection of prostate disease in the elderly. PSA value was the only clinical variable associated with an increased rate of prostate cancer in men ≥ 70 and older (p=0.02). DRE, PSA, and prostate volume are important parameters associated with an increase in prostate cancer detection rate in men over 70 years of age.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":"56 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139601456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the Stress of Health Workers of Psychiatry Clinic and Dermatovenerology Clinic 精神科和皮肤性病科门诊医务人员压力分析

Experimental and Applied Biomedical Research (EABR) Pub Date : 2023-10-31 DOI: 10.2478/sjecr-2021-0086

Kristina Mladenovic, Natasa Radojicic, Rasa Mladenovic, Mirjana Jovanovic

{"title":"Analysis of the Stress of Health Workers of Psychiatry Clinic and Dermatovenerology Clinic","authors":"Kristina Mladenovic, Natasa Radojicic, Rasa Mladenovic, Mirjana Jovanovic","doi":"10.2478/sjecr-2021-0086","DOIUrl":"https://doi.org/10.2478/sjecr-2021-0086","url":null,"abstract":"Abstract Stress at a workplace represents stress caused by the job of a person, which occurs when the demands of the workplace are not in accordance with the needs of health workers. Two basic types of pathological stress at workplace are: burnout syndrome at work and technostress. The set goals were to assess the level of stress among health workers employed by the Psychiatric Clinic and the Dermatovenerology Clinic, and compare the results obtained, and identify a group of health workers exposed to the highest level of stress within the studied healthcare institutions. A total of 93 respondents were included in the study, of which 43 were from the Dermatovenerology Clinic and 50 from the Psychiatric Clinic. In the process of collecting data from respondents, the questionnaire used is modified version of “The Workplace Stress Scale”. The most important is to note that there is no correlation between night-shift work and stress level, as well as gender, or level of education, even though many studies in the world indicate a connection between these factors - which is marked as an increased risk of stress. Starting from the goals of the work, it is concluded that employees at the Dermatovenerology Clinic are more exposed to stress than employees in the Psychiatric Clinic. The level of education, gender, age, shift work does not affect the level of stress. The factor that most affects the level of stress is personal income and a short deadline for executing the given actions.","PeriodicalId":491601,"journal":{"name":"Experimental and Applied Biomedical Research (EABR)","volume":"76 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0