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[18F]FDG PET/CT imaging of giant cell arteritis: contemporary practical guide to image acquisition and interpretation. [18F]巨细胞动脉炎的FDG PET/CT成像：当代图像采集和解释的实用指南。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 DOI: 10.23736/S1824-4785.25.03611-8
Phillip Yin, Gad Abikhzer, Jean-Louis Alberini, Riemer H Slart
{"title":"[18F]FDG PET/CT imaging of giant cell arteritis: contemporary practical guide to image acquisition and interpretation.","authors":"Phillip Yin, Gad Abikhzer, Jean-Louis Alberini, Riemer H Slart","doi":"10.23736/S1824-4785.25.03611-8","DOIUrl":"10.23736/S1824-4785.25.03611-8","url":null,"abstract":"<p><p>Giant cell arteritis (GCA) is the most common of the large vessel vasculitides, with [<sup>18</sup>F] fluorodeoxyglucose (FDG) PET/CT indicated for evaluation of suspected large vessel involvement. Advances in PET/CT technology, particularly with digital PET, have significantly improved the assessment of cranial artery involvement in GCA. Recent guidelines have been updated to incorporate [<sup>18</sup>F]FDG PET/CT imaging in the diagnosis of GCA. This review article provides a practical guide to the most recent recommendations regarding PET/CT study indications, image acquisition and interpretation criteria for GCA, while discussing potential pitfalls and future research directions in the field.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"69 1","pages":"69-81"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spondylodiscitis. Spondylodiscitis。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 DOI: 10.23736/S1824-4785.25.03619-2
Edel Noriega-Álvarez, Ringo Manta, Andor W Glaudemans, Olivier Gheysens, Virginia Peiró
{"title":"Spondylodiscitis.","authors":"Edel Noriega-Álvarez, Ringo Manta, Andor W Glaudemans, Olivier Gheysens, Virginia Peiró","doi":"10.23736/S1824-4785.25.03619-2","DOIUrl":"10.23736/S1824-4785.25.03619-2","url":null,"abstract":"<p><p>Diagnosis of spondylodiscitis remains a challenge for clinicians. It results from various causative agents and conditions that can be challenging to identify. Prompt and appropriate treatment are necessary to prevent long-term irreversible complications and sequelae. The diagnosis of spondylodiscitis often constitutes a major challenge for the clinicians, and relies on the combination of clinical, laboratory and imaging findings. Various imaging techniques can be used for the workup of spondylodiscitis, with magnetic resonance imaging and 18-fluoro-deoxy-glucose positron emission tomography, combined with a CT being the most commonly used in daily practice. The aim of this review is to provide general information about indications and protocols for [<sup>18</sup>F]FDG PET/CT imaging in spinal infections, focusing on spondylodiscitis, in adults.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"69 1","pages":"17-29"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDG PET/CT for imaging of infection and inflammation: a practical approach. FDG PET/CT用于感染和炎症的成像：一种实用的方法。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 DOI: 10.23736/S1824-4785.25.03624-6
Gad Abikhzer, Ora Israel
{"title":"FDG PET/CT for imaging of infection and inflammation: a practical approach.","authors":"Gad Abikhzer, Ora Israel","doi":"10.23736/S1824-4785.25.03624-6","DOIUrl":"https://doi.org/10.23736/S1824-4785.25.03624-6","url":null,"abstract":"","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"69 1","pages":"1-3"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of FDG PET/CT in bacteremia and fever of unknown origin: a pictorial overview of finding the culprit. FDG PET/CT在菌血症和不明原因发热中的作用：寻找罪魁祸首的图像概述。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 DOI: 10.23736/S1824-4785.25.03618-0
Ayah A Nawwar, Soren Hess, Lucia Leccisotti, Francois Jamar, Edel Noriega-Alvarez, Domenico Albano, Olivier Gheysens
{"title":"Role of FDG PET/CT in bacteremia and fever of unknown origin: a pictorial overview of finding the culprit.","authors":"Ayah A Nawwar, Soren Hess, Lucia Leccisotti, Francois Jamar, Edel Noriega-Alvarez, Domenico Albano, Olivier Gheysens","doi":"10.23736/S1824-4785.25.03618-0","DOIUrl":"10.23736/S1824-4785.25.03618-0","url":null,"abstract":"<p><p><sup>18</sup>F fluorodeoxyglucose ([<sup>18</sup>F]FDG) positron emission tomography/computed tomography (PET/CT) has established itself as a critical diagnostic tool in the evaluation of patients with bacteremia and fever of unknown origin (FUO), particularly following futile conventional investigations. These conditions are often challenging due to diverse underlying etiologies, including infections, inflammatory conditions and malignancies. PET/CT has the advantage of being a whole-body imaging technique with high sensitivity for detecting areas of increased metabolism often associated with infection or inflammation. In bacteremia, [<sup>18</sup>F]FDG PET/CT can help identify metastatic infections, endocarditis, or abscesses which may be clinically silent and missed on conventional imaging. In FUO, it helps to identify underlying etiologies, directing treatment and management strategies. This review aims to describe the role of PET/CT imaging in these diverse clinical scenarios. Perspectives in the field, including novel equipment and tracers, will be briefly discussed.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"69 1","pages":"4-16"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FDG PET/CT in vascular graft infection: a pictorial review. FDG PET/CT在血管移植感染中的应用综述。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 DOI: 10.23736/S1824-4785.25.03612-X
Manar Badarna, Zohar Keidar, Elite Arnon-Sheleg
{"title":"FDG PET/CT in vascular graft infection: a pictorial review.","authors":"Manar Badarna, Zohar Keidar, Elite Arnon-Sheleg","doi":"10.23736/S1824-4785.25.03612-X","DOIUrl":"10.23736/S1824-4785.25.03612-X","url":null,"abstract":"<p><p>Vascular graft infections (VGI) are rare but severe complications following vascular surgery, with significant morbidity and mortality. Diagnosing VGI requires a multidisciplinary approach combining clinical, laboratory, and imaging findings. While CTA remains the first-line imaging modality, its limitations in detecting chronic or low-grade infections highlight the value of advanced nuclear medicine techniques, particularly [<sup>18</sup>F]FDG PET/CT. In this review, we discuss the role of [<sup>18</sup>F]FDG PET/CT in diagnosing VGI, emphasizing its high sensitivity and negative predictive value, which are critical for ruling out infection. Nevertheless, there are currently no universally accepted criteria for analyzing PET/CT findings in VGI, which poses challenges for consistent interpretation and clinical decision-making. This review aims to provide a comprehensive understanding of FDG PET/CT imaging in the context of VGI by exploring visual grading scales, uptake patterns, and semi-quantitative parameters while highlighting potential pitfalls such as post-surgical inflammation and false-positive results due to graft materials or surgical adhesives. Through a series of illustrative cases, we outline characteristic imaging patterns of infected and non-infected grafts, offering practical guidance for accurate interpretation. Additionally, we discuss the evolving role of FDG PET/CT in assessing treatment response and guiding follow-up in VGI management. This pictorial review seeks to enhance diagnostic accuracy and bridge the gap in standardized PET/CT interpretation criteria, ultimately contributing to improved patient care.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"69 1","pages":"61-68"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteomyelitis in complicated bones: the role of FDG PET/CT. 复杂骨的骨髓炎：FDG PET/CT的作用。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 DOI: 10.23736/S1824-4785.25.03623-4
Alfred Ankrah, Honest Ndlovu, Kgomotso Mokoala, Mike Sathekge
{"title":"Osteomyelitis in complicated bones: the role of FDG PET/CT.","authors":"Alfred Ankrah, Honest Ndlovu, Kgomotso Mokoala, Mike Sathekge","doi":"10.23736/S1824-4785.25.03623-4","DOIUrl":"10.23736/S1824-4785.25.03623-4","url":null,"abstract":"<p><p>Osteomyelitis in infections encompasses heterogeneous group of condition that frequently have high morbidity and comes at a huge cost to healthcare system. Accurate and early diagnosis is important for the proper management of the condition. FDG PET/CT has been found useful in the osteomyelitis of complicated bones, including prosthetic joint infections, fracture related infections and sternal wound infections. The altered anatomy and the replacement of marrow in some cases of metallic implant makes the use of anatomic-based methods less optimal. FDG PET/CT has been found to be useful under these circumstances, however, it also has its own limitation of lack of specificity especially due to inflammation. Recent meta-analysis of the role of FDG PET/CT in complicated osteomyelitis have result in the validation defined the indications for its use. This has led to the publication of best use criteria and recommendations of by joint committees of major nuclear medicine societies.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"69 1","pages":"30-38"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[18F]FDG PET/CT in cardiovascular infections: a practical approach. [18]FDG PET/CT在心血管感染诊断中的应用。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 DOI: 10.23736/S1824-4785.25.03616-7
Hanan Zahed, Matthieu Pelletier-Galarneau, Gad Abikhzer
{"title":"[18F]FDG PET/CT in cardiovascular infections: a practical approach.","authors":"Hanan Zahed, Matthieu Pelletier-Galarneau, Gad Abikhzer","doi":"10.23736/S1824-4785.25.03616-7","DOIUrl":"10.23736/S1824-4785.25.03616-7","url":null,"abstract":"<p><p>Cardiovascular infections have a high mortality rate requiring prompt diagnosis and timely management. [<sup>18</sup>F]fluorodeoxyglucose ([<sup>18</sup>F]FDG) positron emission tomography/computed tomography (PET/CT) has emerged as a valuable diagnostic imaging modality for various cardiovascular infections, including infective endocarditis (IE) and cardiac implantable electronic device (CIED) infections, particularly when the diagnosis remains challenging. In this article, we provide an overview of the epidemiology and clinical presentation of IE and CIED-related infections, the indications for <sup>18</sup>F-FDG-PET/CT and its incremental role in establishing diagnosis as well as illustrate a variety of clinical cases and discuss interpretation criteria.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"69 1","pages":"48-60"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[18F]FDG PET/CT for the diagnosis of diabetic foot osteomyelitis. [18]FDG PET/CT对糖尿病足骨髓炎的诊断价值。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2025-03-01 Epub Date: 2025-02-10 DOI: 10.23736/S1824-4785.25.03614-3
Aubert Roy, Huy LE, Gad Abikhzer
{"title":"[18F]FDG PET/CT for the diagnosis of diabetic foot osteomyelitis.","authors":"Aubert Roy, Huy LE, Gad Abikhzer","doi":"10.23736/S1824-4785.25.03614-3","DOIUrl":"10.23736/S1824-4785.25.03614-3","url":null,"abstract":"<p><p>Infected foot ulcers are common complications in diabetic patients and frequently progress to osteomyelitis. [<sup>18</sup>F]fluorodeoxyglucose ([<sup>18</sup>F]FDG) positron emission tomography/computed tomography (PET/CT) has emerged as a practical and accurate imaging modality to differentiate between soft tissue infection and diabetic foot osteomyelitis (DFO). This study describes [<sup>18</sup>F]FDG PET/CT indications, diagnostic accuracy, imaging protocols, interpretation criteria and pitfalls for the work-up of DFO.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":" ","pages":"39-47"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of F-18 fluorodeoxyglucose PET/CT in the evaluation and treatment of hepatobiliary tumors. F-18氟脱氧葡萄糖PET/CT在肝胆肿瘤评价与治疗中的研究进展
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2024-12-01 DOI: 10.23736/S1824-4785.24.03574-X
Bradley J Girod, Asha Kandathil
{"title":"A review of F-18 fluorodeoxyglucose PET/CT in the evaluation and treatment of hepatobiliary tumors.","authors":"Bradley J Girod, Asha Kandathil","doi":"10.23736/S1824-4785.24.03574-X","DOIUrl":"10.23736/S1824-4785.24.03574-X","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) and biliary tract cancers (BTC) pose significant diagnostic and therapeutic challenges. Magnetic resonance imaging (MRI) and multiphase computed tomography (CT) have been the preferred imaging modalities for diagnosis, staging, and surveillance of patients with these malignancies. The best clinical outcomes depend on the appropriate selection of treatment options from the tools available in neo-adjuvant therapy, surgical resection, locoregional therapy, liver transplantation, and adjuvant therapy. While not a part of the routine diagnostic work-up or follow-up, F-18 fluorodeoxyglucose positron emission tomography (FDG PET/CT) can inform therapeutic decision making and help avoid futile surgeries by detecting unsuspected distant metastases. Additionally, metabolic information obtained with FDG PET/CT has prognostic value, predicting treatment response and survival. In patients with HCC metabolic parameters obtained by FDG PET/CT have been shown to correlate with microvascular invasion and predict recurrence in orthotopic transplant recipients. This article will highlight studies that have evaluated the role of FDG PET/CT in diagnosis, staging and therapeutic response assessment in patients with hepatobiliary cancers.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"68 4","pages":"245-258"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radioembolization of HCC and secondary hepatic tumors: a comprehensive review. 肝癌和继发性肝肿瘤的放射栓塞治疗：全面回顾。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2024-12-01 Epub Date: 2024-08-01 DOI: 10.23736/S1824-4785.24.03572-6
Ahmad Arar, Alex Heglin, Shriya Veluri, Mhd Wisam Alnablsi, Jamaal L Benjamin, Moaz Choudhary, Anil Pillai
{"title":"Radioembolization of HCC and secondary hepatic tumors: a comprehensive review.","authors":"Ahmad Arar, Alex Heglin, Shriya Veluri, Mhd Wisam Alnablsi, Jamaal L Benjamin, Moaz Choudhary, Anil Pillai","doi":"10.23736/S1824-4785.24.03572-6","DOIUrl":"10.23736/S1824-4785.24.03572-6","url":null,"abstract":"<p><p>Transarterial radioembolization (TARE), also called Selective Internal Radiation Therapy (SIRT), has emerged as an effective locoregional therapy for primary and secondary hepatic tumors, utilizing yttrium-90 (Y90) microspheres and other agents such as holmium-166 and rhenium-188. TARE has various applications in the management of HCC across different BCLC stages. Radiation segmentectomy, which involves administering high doses of Y90 (>190 Gy), can be both curative and ablative, achieving complete necrosis of the tumor. In contrast, radiation lobectomy involves administering a lower dose of Y90 (80-120 Gy) as a neoadjuvant treatment modality to improve local control and induce future liver remnant (FLR) hypertrophy in patients who are planned to undergo surgery but have insufficient FLR. Modified radiation lobectomy combines both techniques and offers several advantages over portal vein embolization (PVE). Y90 is also used in downstaging HCC patients outside liver transplantation criteria, as well as bridging those awaiting liver transplantation (LT). Multiple studies and combined analyses were described to highlight the outcomes of TARE and compare it with other treatment modalities, including TACE and sorafenib. Additionally, the review delves into the efficacy and safety of radioembolization in managing metastatic colorectal cancer and other metastatic tumors to the liver. Recent studies have emphasized the role of personalized dosimetry for improved outcomes, and thus we described the different methods used for this purpose. Pretherapy imaging, estimating lung shunt, selection of therapeutic radionuclides, adverse effects, and cost-effectiveness were all discussed as well.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":" ","pages":"270-287"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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