the Quarterly Journal of Nuclear Medicine and Molecular Imaging最新文献

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Nuclear medicine and pediatric nephro-urology: a long-lasting successful partnership. 核医学与小儿肾脏-泌尿学:长期的成功合作。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2024-03-01 Epub Date: 2024-03-06 DOI: 10.23736/S1824-4785.24.03557-X
Ana I Santos, Rita T Ferreira
{"title":"Nuclear medicine and pediatric nephro-urology: a long-lasting successful partnership.","authors":"Ana I Santos, Rita T Ferreira","doi":"10.23736/S1824-4785.24.03557-X","DOIUrl":"10.23736/S1824-4785.24.03557-X","url":null,"abstract":"<p><p>Congenital anomalies of the kidney and urinary tract, as well as urinary infections, are very frequent in children. After the clinical and laboratory evaluation, the first imaging procedure to be done is a renal and bladder ultrasound, but afterwards, a main contribution comes from nuclear medicine. Through minimally invasive and sedation-free procedures, nuclear medicine allows the evaluation of the functional anatomy of the urinary tract, and the quantification of renal function and drainage. If pediatric dosage cards provided by scientific societies are used, radiation exposure can also be low. In the pediatric conditions previously mentioned, nuclear medicine is used both for initial diagnosis and follow-up, mostly in cases of suspicion of ureteropelvic or ureterovesical junction syndromes, as well as vesicoureteral reflux or renal scars of febrile infectious episodes. Pediatric nephro-urology constitutes a significant workload of pediatric nuclear medicine departments. The following paragraphs are a revision of the renal radiopharmaceuticals, as well as the nuclear nephro-urology procedures - dynamic and static renal scintigraphy, and direct and indirect radionuclide cystography. A summary of the techniques, main indications, interpretation criteria and pitfalls will be provided. Some future directions for the field are also pointed out, among which the most relevant is the need for nuclear medicine professionals to use standardized protocols and integrate multidisciplinary teams with other pediatric and adult health professionals that manage these life-long pediatric pathologies, which are recognized as an important cause of adult chronic kidney disease.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140040664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovations in imaging modalities: a comparative review of MRI, long-axial field-of-view PET, and full-ring CZT-SPECT in detecting bone metastases. 成像方式的创新:MRI、长轴视野PET和全环CZT-SPECT在检测骨转移中的比较综述。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2023-12-01 Epub Date: 2023-10-23 DOI: 10.23736/S1824-4785.23.03537-9
Roberto Moretti, Guenda Meffe, Salvatore Annunziata, Amedeo Capotosti
{"title":"Innovations in imaging modalities: a comparative review of MRI, long-axial field-of-view PET, and full-ring CZT-SPECT in detecting bone metastases.","authors":"Roberto Moretti, Guenda Meffe, Salvatore Annunziata, Amedeo Capotosti","doi":"10.23736/S1824-4785.23.03537-9","DOIUrl":"10.23736/S1824-4785.23.03537-9","url":null,"abstract":"<p><p>The accurate diagnosis of bone metastasis, a condition in which cancer cells have spread to the bone, is essential for optimal patient care and outcome. This review provides a detailed overview of the current medical imaging techniques used to detect and diagnose this critical condition focusing on three cardinal imaging modalities: positron emission tomography (PET), single photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI). Each of these techniques has unique advantages: PET/CT combines functional imaging with anatomical imaging, allowing precise localization of metabolic abnormalities; the SPECT/CT offers a wider range of radiopharmaceuticals for visualizing specific receptors and metabolic pathways; MRI stands out for its unparalleled ability to produce high-resolution images of bone marrow structures. However, as this paper shows, each modality has its own limitations. The comprehensive analysis does not stop at the technical aspects, but ventures into the wider implications of these techniques in a clinical setting. By understanding the synergies and shortcomings of these modalities, healthcare professionals can make diagnostic and therapeutic decisions. Furthermore, at a time when medical technology is evolving at a breakneck pace, this review casts a speculative eye towards future advances in the field of bone metastasis imaging, bridging the current state with future possibilities. Such insights are essential for both clinicians and researchers navigating the complex landscape of bone metastasis diagnosis.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current update and future applications of bone metastasis imaging: what's next? 骨转移成像的最新进展和未来应用:下一步是什么?
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2023-12-01 Epub Date: 2023-11-06 DOI: 10.23736/S1824-4785.23.03539-2
Emmanouil Panagiotidis, Jules Zhang-Yin
{"title":"Current update and future applications of bone metastasis imaging: what's next?","authors":"Emmanouil Panagiotidis, Jules Zhang-Yin","doi":"10.23736/S1824-4785.23.03539-2","DOIUrl":"10.23736/S1824-4785.23.03539-2","url":null,"abstract":"","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of MRI for the imaging of metastatic bone lesions. 使用核磁共振成像对转移性骨病变进行成像。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2023-12-01 DOI: 10.23736/S1824-4785.23.03538-0
Daniel Poon, Christopher Tang, Sanjay Vijayanathan, Davina Mak
{"title":"The use of MRI for the imaging of metastatic bone lesions.","authors":"Daniel Poon, Christopher Tang, Sanjay Vijayanathan, Davina Mak","doi":"10.23736/S1824-4785.23.03538-0","DOIUrl":"10.23736/S1824-4785.23.03538-0","url":null,"abstract":"<p><p>Skeletal metastatic disease accounts for significant overall morbidity in cancer patients. Accurate and accessible imaging forms an integral part of the investigation for patients with suspected or known skeletal metastatic disease; it is considered indispensable in making appropriate oncological treatment decisions. Magnetic resonance imaging (MRI) is a contemporary imaging modality that provides excellent spatial and contrast resolution for bone and soft tissues. Therefore, it is particularly useful for imaging patients suffering from metastatic skeletal disease. This review provides a fundamental overview of the physics and image generation of MRI. The most commonly used MRI sequences in the investigation of metastatic skeletal disease are also discussed. Additionally, a review of the pathophysiological basis of metastatic bone disease is presented, along with an introduction to the interpretation of MRI sequences obtained for metastatic bone disease. Finally, the strengths and drawbacks of MRI are considered in comparison to alternative imaging modalities for the investigation of this common and important oncological complication.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138488855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of 18F-NaF PET/CT in bone metastases. 18F-NaF-PET/CT在骨转移瘤中的作用。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2023-12-01 Epub Date: 2023-09-26 DOI: 10.23736/S1824-4785.23.03534-3
Jules Zhang-Yin, Emmanouil Panagiotidis
{"title":"Role of 18F-NaF PET/CT in bone metastases.","authors":"Jules Zhang-Yin, Emmanouil Panagiotidis","doi":"10.23736/S1824-4785.23.03534-3","DOIUrl":"10.23736/S1824-4785.23.03534-3","url":null,"abstract":"<p><p>The use of <sup>18</sup>F sodium fluoride (<sup>18</sup>F-NaF) in positron emission tomography (PET/CT) is increasing. This resurgence of an old tracer has been driven by several factors, including its superior diagnostic performance over standard 99mTc-based bone scintigraphy (BS), availability of PET/CT imaging systems, a shortened examination time and an increase in the number of regional commercial PET radiotracer distribution. In this special article, we aimed to highlight the current place of the <sup>18</sup>F-NaF PET/CT in the imaging of bone metastases (BM) in a variety of malignancies. A special focus is given to the following ones: breast cancer (BC), prostate cancer (PCa). Also, other malignancies such as bladder cancer, lung cancer, thyroid cancer, multiple myeloma, head and neck cancer, hepatocellular carcinoma have been addressed. At last, we summarize the advantages and limits of the <sup>18</sup>F-NaF PET/CT compared to other imaging modalities in these settings.</p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41148765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphology supporting function: attenuation correction for SPECT/CT, PET/CT, and PET/MR imaging. 形态学支持功能:衰减校正SPECT/CT, PET/CT, PET/MR成像。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2016-03-01 Epub Date: 2015-11-17
Tzu C Lee, Adam M Alessio, Robert M Miyaoka, Paul E Kinahan
{"title":"Morphology supporting function: attenuation correction for SPECT/CT, PET/CT, and PET/MR imaging.","authors":"Tzu C Lee, Adam M Alessio, Robert M Miyaoka, Paul E Kinahan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Both SPECT, and in particular PET, are unique in medical imaging for their high sensitivity and direct link to a physical quantity, i.e. radiotracer concentration. This gives PET and SPECT imaging unique capabilities for accurately monitoring disease activity for the purposes of clinical management or therapy development. However, to achieve a direct quantitative connection between the underlying radiotracer concentration and the reconstructed image values several confounding physical effects have to be estimated, notably photon attenuation and scatter. With the advent of dual-modality SPECT/CT, PET/CT, and PET/MR scanners, the complementary CT or MR image data can enable these corrections, although there are unique challenges for each combination. This review covers the basic physics underlying photon attenuation and scatter and summarizes technical considerations for multimodal imaging with regard to PET and SPECT quantification and methods to address the challenges for each multimodal combination. </p>","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deafness in myxoedema. 粘液水肿性耳聋。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 1979-04-01 DOI: 10.1093/OXFORDJOURNALS.QJMED.A067580
W. van't Hoff, D. W. Stuart
{"title":"Deafness in myxoedema.","authors":"W. van't Hoff, D. W. Stuart","doi":"10.1093/OXFORDJOURNALS.QJMED.A067580","DOIUrl":"https://doi.org/10.1093/OXFORDJOURNALS.QJMED.A067580","url":null,"abstract":"Deafness has been demonstrated in 41 (85 per cent) of a consecutive series of 48 patients with myxoedema. There was no difference between the incidence of high and low frequency hearing loss. Severe myxoedema was associated with a higher incidence of deafness than mild myxoedema. Hearing was retested when patients were euthyroid following treatment with thyroxine. Improvement in hearing was found in 55 out of 75 deaf ears (73 per cent) and return to normal hearing occurred in 17 (23 per cent) of the 75 deaf ears.","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"1979-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81483543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
Angio-immunoblastic lymphadenopathy: report of ten cases and review of the literature. 血管免疫母细胞性淋巴结病:附十例报告并文献复习。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 1979-01-01 DOI: 10.1093/OXFORDJOURNALS.QJMED.A067563
M. Cullen, A. Stansfeld, R. Oliver, T. Lister, J. Malpas
{"title":"Angio-immunoblastic lymphadenopathy: report of ten cases and review of the literature.","authors":"M. Cullen, A. Stansfeld, R. Oliver, T. Lister, J. Malpas","doi":"10.1093/OXFORDJOURNALS.QJMED.A067563","DOIUrl":"https://doi.org/10.1093/OXFORDJOURNALS.QJMED.A067563","url":null,"abstract":"Angio-immunoblastic lymphadenopathy (AIL) is a disease of unknown aetiology and pathogenesis. It has features of hyperimmunity, immune deficiency and can behave like a malignant lymphoma. An underlying abnormality of T-cell regulatory function has been proposed. We report ten patients with AIL followed prospectively and review 200 cases from the literature. As well as showing the typical features described in previous retrospective series namely: constitutional symptoms, generalized lymphadenopathy, hepatosplenomegaly, skin eruptions, hypergammaglobulinaemia and characteristic lymph node histology; four patients had oedema with ascites or pleural effusions associated with hyponatraemia and hypoalbuminaemia. We have also observed low free thyroxine indices in three patients with elevated TSH levels in two, but without clinical features of hypothyroidism. Seven of the patients in this study were treated with prednisone and cyclophosphamide. Three achieved complete remission but only one patient has survived longer than two years. Failure to achieve complete remission has been associated with a 90 per cent mortality within one year of the onset of disease in the reports reviewed. Corticosteroids alone have produced only a 40 per cent rate of remission. The management of poor responders, non-responders and many relapse cases in unsatisfactory. More instensive chemotherapy is very hazardous, increasing the already high risk of severe infections, and is often unsuccessful. Histological features recently reported to represent co-existent immunoblastic lymphoma at diagnosis were recognized in three of our patients, two of which went on to develop definite lymphoma.","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76716924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 70
Dissecting aortic aneurysms: a clinicopathological study. I. Clinical and gross pathological findings. 夹层主动脉瘤:临床病理研究。1 .临床及大体病理表现。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 1979-01-01 DOI: 10.1093/OXFORDJOURNALS.QJMED.A067566
J. C. Leonard, P. Hasleton
{"title":"Dissecting aortic aneurysms: a clinicopathological study. I. Clinical and gross pathological findings.","authors":"J. C. Leonard, P. Hasleton","doi":"10.1093/OXFORDJOURNALS.QJMED.A067566","DOIUrl":"https://doi.org/10.1093/OXFORDJOURNALS.QJMED.A067566","url":null,"abstract":"One hundred and seventy-one patients with dissecting aneurysm seen between 1951 and 1976 at three hospitals in Manchester were studied. There were 60 proximal dissections, 80 distal dissections, 10 abdominal dissections and in 21 the site of origin was uncertain. Pain was the major symptom in 88 per cent of patients; radiation of pain to the interscapular region was much more common in distal dissections. Systemic hypertension was present in 77 per cent, being commoner in distal dissections (83 per cent) than in proximal dissections (70 per cent). Aortic incompetence, hemiplegia and shock were all more common in proximal dissections. Post-mortem examination was performed in 125 patients. Eighty-four per cent of proximal dissections had ruptured, 74 per cent into the pericardium and five per cent into the left pleural cavity. Seventy per cent of distal dissections had ruptured, 11 per cent into the pericardium and 41 per cent into the left pleural cavity. The extent of the dissection was analysed, and it was shown that 25 per cent of distal dissections had extended proximally into the ascending aorta and arch. This implies that diagnosis of the site of origin of dissection from clinical signs and the plain chest-radiograph is inaccurate. Aortography is required for precise assessment. Since treatment often varies with the site of dissection, aortography should be performed in most patients surviving the first few hours. Attention is drawn to the frequency (10.4 per cent) of multiple aortic lesions, and to the occasional aetiological significance of giant-cell arteritis, and, possibly, hypothyroidism.","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74267518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 79
Neurological complications of carbon monoxide poisoning. 一氧化碳中毒的神经系统并发症。
IF 1.5 4区 医学
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 1967-10-01 DOI: 10.1093/OXFORDJOURNALS.QJMED.A067122
H. Garland, J. Pearce
{"title":"Neurological complications of carbon monoxide poisoning.","authors":"H. Garland, J. Pearce","doi":"10.1093/OXFORDJOURNALS.QJMED.A067122","DOIUrl":"https://doi.org/10.1093/OXFORDJOURNALS.QJMED.A067122","url":null,"abstract":"","PeriodicalId":49135,"journal":{"name":"the Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"1967-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73917060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 163
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