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The Rising Threat of Antibiotic Resistance 不断上升的抗生素耐药性威胁
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-11-20 DOI: 10.1109/mpuls.2023.3324236
Leslie Mertz
{"title":"The Rising Threat of Antibiotic Resistance","authors":"Leslie Mertz","doi":"10.1109/mpuls.2023.3324236","DOIUrl":"https://doi.org/10.1109/mpuls.2023.3324236","url":null,"abstract":"We are Out of time. New, effective antibiotics are required to face the real and growing global threat from resistant and too often deadly bacterial infections. According to the World Health Organization, “Antibiotic resistance is rising to dangerously high levels in all parts of the world. New resistance mechanisms are emerging and spreading globally, threatening our ability to treat common infectious diseases.” The organization adds, “A growing list of infections, such as pneumonia, tuberculosis, blood poisoning, gonorrhea, and foodborne diseases, are becoming harder, and sometimes impossible, to treat as antibiotics become less effective” <xref ref-type=\"bibr\" r xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">[1]</xref>\u0000.","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138509185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To Sleep, Perchance to Dream. 沉睡，偶然入梦
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-11-01 DOI: 10.1109/MPULS.2024.3354568
Jim Banks
{"title":"To Sleep, Perchance to Dream.","authors":"Jim Banks","doi":"10.1109/MPULS.2024.3354568","DOIUrl":"10.1109/MPULS.2024.3354568","url":null,"abstract":"<p><p>Most of us know the restorative value of an early night, so on some level we instinctively understand that sleep is good for both the body and the mind. Now, a growing body of research is starting to show just how vital sleep is to our overall health and longevity. Some believe that laughter is no longer the best medicine-sleep is.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breakthroughs in Brain Implants. 大脑植入技术的突破。
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-11-01 DOI: 10.1109/MPULS.2024.3353668
Zara Abrams
{"title":"Breakthroughs in Brain Implants.","authors":"Zara Abrams","doi":"10.1109/MPULS.2024.3353668","DOIUrl":"10.1109/MPULS.2024.3353668","url":null,"abstract":"<p><p>In 2023, Brain implants got a big boost. Neuralink, Elon Musk's startup, began recruiting for its first clinical trial for paralysis patients; Precision Neuroscience received breakthrough designation from the Food and Drug Administration (FDA), allowing it to fast-track its own trials. Meanwhile, scientific advances are revealing promising new applications for such devices, including more comprehensive restoration of speech, sight, hearing, and movement to people who have lost those abilities, as well as help for psychiatric conditions, such as eating disorders and depression.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Monitoring and Treatment Technologies for the Heart. 新型心脏监测和治疗技术。
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-11-01 DOI: 10.1109/MPULS.2024.3354148
Leslie Mertz
{"title":"Novel Monitoring and Treatment Technologies for the Heart.","authors":"Leslie Mertz","doi":"10.1109/MPULS.2024.3354148","DOIUrl":"10.1109/MPULS.2024.3354148","url":null,"abstract":"<p><p>Cardiovascular disease may be the world's leading killer of men and women, but new technologies are in development that could help lessen its impact. Among them are a variety of innovative external and internal patches that employ flexible and stretchable materials, machine learning, and other tactics to monitor heart activity and function, and in some cases to provide on-the-spot treatment.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Gene Editing Juggernaut is Picking Up Speed. 基因编辑巨轮正在加速前进。
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-09-01 DOI: 10.1109/MPULS.2023.3344054
Jim Banks
{"title":"The Gene Editing Juggernaut is Picking Up Speed.","authors":"Jim Banks","doi":"10.1109/MPULS.2023.3344054","DOIUrl":"10.1109/MPULS.2023.3344054","url":null,"abstract":"<p><p>CRISPR-Cas9, the tool for editing genes by precisely cutting DNA and letting the body's natural DNA repair processes take over, deservedly led to Nobel prizes in 2020 for its pioneers, Emmanuelle Charpentier and Jennifer Doudna. Since their breakthroughs in 2012, the technology has moved forward in leaps and bounds, and techniques to manipulate genes that were once the realm of science fiction are becoming very much science \"fact.\"</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139486607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NASA Takes on Climate Change: Focusing Tech From Space to Earth. 美国国家航空航天局应对气候变化：将技术从太空聚焦到地球。
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-09-01 DOI: 10.1109/MPULS.2023.3344080
Leslie Mertz
{"title":"NASA Takes on Climate Change: Focusing Tech From Space to Earth.","authors":"Leslie Mertz","doi":"10.1109/MPULS.2023.3344080","DOIUrl":"10.1109/MPULS.2023.3344080","url":null,"abstract":"<p><p>When the Voyager 1 spacecraft was hurtling past Neptune to points beyond, its camera swung back to snap an image of Earth, a tiny spot of light in the vast, dark expanse. That 1990 image offered a stark reminder of just how vulnerable our planet is. The U.S. National Aeronautics and Space Administration (NASA) remains focused on space exploration today, but is also providing an Earth-side role, notably in understanding climate change and how it affects human health, and in inspiring new research and products to help people cope with varying weather patterns and the threats they bring.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139486602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Brain Cells That Make Us Uniquely Human. 让我们成为独特人类的脑细胞
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-09-01 DOI: 10.1109/MPULS.2023.3344068
Zara Abrams
{"title":"The Brain Cells That Make Us Uniquely Human.","authors":"Zara Abrams","doi":"10.1109/MPULS.2023.3344068","DOIUrl":"10.1109/MPULS.2023.3344068","url":null,"abstract":"<p><p>For over a century, scientists have known that the brain contains multiple cell types, dating back to Santiago Ramón y Cajal's earliest observations of brain tissue under a microscope. But until recently, we lacked the tools to study those cells with enough resolution to truly understand their roles.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139486605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treating the Brain With Focused Ultrasound. 用聚焦超声波治疗大脑
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-09-01 DOI: 10.1109/MPULS.2023.3344082
Mary Bates
{"title":"Treating the Brain With Focused Ultrasound.","authors":"Mary Bates","doi":"10.1109/MPULS.2023.3344082","DOIUrl":"10.1109/MPULS.2023.3344082","url":null,"abstract":"<p><p>Focused ultrasound is an early stage, noninvasive therapy with the potential to treat a range of medical conditions. Like diagnostic ultrasound, it uses sound waves above the range of human hearing. But its purpose is to interact with tissues in the body, rather than just produce images of them. In focused ultrasound, multiple, intersecting beams of high frequency sound are aimed to converge on specific targets deep within the body. There, the ultrasound energy can act in multiple ways to either modify or destroy tissue.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139486610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DNA Testing for Preventative Health: Do Outcomes Justify Continued Investment? DNA检测用于预防健康:结果证明继续投资是合理的吗?
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-07-01 DOI: 10.1109/MPULS.2023.3324240
Jim Banks
{"title":"DNA Testing for Preventative Health: Do Outcomes Justify Continued Investment?","authors":"Jim Banks","doi":"10.1109/MPULS.2023.3324240","DOIUrl":"10.1109/MPULS.2023.3324240","url":null,"abstract":"<p><p>In The U.K., a heated debate is raging in the genetics community about a not-so-new technology and its role in public health. Cheap genetic tests to discover our ancestry have become familiar consumer products, and our genes can tell us a lot about our ancestry, so it is an appealing idea that they can tell us about our susceptibility to serious diseases. Polygenic risk scores (PRS)-generated by sequencing multiple parts of a person's DNA-are said by some to hold the key to helping people avoid everything from type 1 diabetes to cardiovascular disease and cancer. This could herald a new era of preventive medicine, and the U.K. is investing heavily, but ultimately, whether or not this a good investment is still being determined.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138177601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Considering Sex in Biomedical Research. 在生物医学研究中考虑性别。
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2023-07-01 DOI: 10.1109/MPULS.2023.3324238
Mary Bates
{"title":"Considering Sex in Biomedical Research.","authors":"Mary Bates","doi":"10.1109/MPULS.2023.3324238","DOIUrl":"10.1109/MPULS.2023.3324238","url":null,"abstract":"<p><p>Until relatively recently, basic biomedical research was almost exclusively conducted with male human, animal, and cell models. It was widely assumed that the research findings and medical treatments developed from these studies could be generalized to the whole population. However, there are sex differences in key biological pathways and processes that can influence a person's disease risk, experience of symptoms, and response to treatment. The lack of female representation in preclinical biomedical research has resulted in gaps in our medical knowledge, with important consequences for women's health. In the past decade, efforts to remedy this historic exclusion have increased, but opportunities remain to make basic biomedical research more equitable, reproducible, and applicable to all people.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138177600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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