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Industry Live Q&A With Cala Health's Alex Kent, Senior Director of Research. 与Cala Health的高级研究总监Alex Kent进行行业现场问答。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-03-01 DOI: 10.1109/MPULS.2025.3554966
Chad Andresen, Alex Kent
{"title":"Industry Live Q&A With Cala Health's Alex Kent, Senior Director of Research.","authors":"Chad Andresen, Alex Kent","doi":"10.1109/MPULS.2025.3554966","DOIUrl":"https://doi.org/10.1109/MPULS.2025.3554966","url":null,"abstract":"<p><p>In this exclusive IEEE Pulse interview, Editor in Chief Chad Andresen engages in an in-depth conversation with Alex Kent, Senior Director of Research at Cala Health, to explore the pioneering work that has positioned the company at the forefront of bioelectronic medicine. Cala Health is known for its transformative approach to treating essential tremor through noninvasive, wrist-worn neuromodulation a therapy that merges rigorous neuroscience with intuitive wearable technology. Kent sheds light on the years of intense, multidisciplinary research that underpins Cala's innovation, including the complex challenges of translating neurophysiological insights into practical, patient-ready therapies. From foundational science to FDA clearance, the journey has been one of perseverance, collaboration, and bold thinking. Listeners will gain rare insight into the scientific backbone of Cala Health's success, the commitment to evidence-based development, and the vision for how individualized bioelectronic medicine can reshape the treatment of chronic neurological conditions. This conversation is a tribute to the relentless pursuit of meaningful, scalable impact and to the researchers who make it possible.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 2","pages":"29-34"},"PeriodicalIF":0.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Noninvasive Medical Devices in Low-Income and Complex Settings: Promise, Challenge, and the Path Ahead. 低收入和复杂环境中的非侵入性医疗设备:承诺、挑战和前进的道路。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-03-01 DOI: 10.1109/MPULS.2025.3554974
Muhammad Hamid Zaman
{"title":"Noninvasive Medical Devices in Low-Income and Complex Settings: Promise, Challenge, and the Path Ahead.","authors":"Muhammad Hamid Zaman","doi":"10.1109/MPULS.2025.3554974","DOIUrl":"10.1109/MPULS.2025.3554974","url":null,"abstract":"<p><p>While noninvasive medical devices for disease diagnosis and management are used routinely in high-income settings, their penetration in low-income countries, and in complex emergency and humanitarian settings remain limited. This article discusses issues of trust, privacy, context, and financial sustainability that need to be addressed for noninvasive devices to live up to their potential and promise in low-income and humanitarian settings.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 2","pages":"26-28"},"PeriodicalIF":0.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Waves of Hope: The Heartbreaking Journey Behind Noninvasive Tumor Treating Fields. 希望之波:非侵入性肿瘤治疗领域背后令人心碎的旅程。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-03-01 DOI: 10.1109/MPULS.2025.3554958
Janet Rae-Dupree
{"title":"Waves of Hope: The Heartbreaking Journey Behind Noninvasive Tumor Treating Fields.","authors":"Janet Rae-Dupree","doi":"10.1109/MPULS.2025.3554958","DOIUrl":"10.1109/MPULS.2025.3554958","url":null,"abstract":"<p><p>Tumor treating fields (TTFields) use alternating waves in roughly the AM radio range to disrupt malignant cell division, shrinking tumors and helping to keep metastases in check. Devices to deliver the therapy currently are available from a single company-Novocure-but a number of clinical trials are underway globally with an eye toward expanding their use. When TTFields were discovered in 2000, researchers suspected that their primary mechanism of action involved physically interfering with mitosis as a cancer cell begins to divide. Healthy cells are not affected by the fields because they have different division rates than malignant cells and different physical and electrical properties. Research has revealed that the fields not only disrupt cancer cell division, but also interfere with DNA damage repair and a malignant cell's ability to move around the body, or metastasize. Studies show that TTFields can trigger cellular stress and chromosomal abnormalities that make it easier for the body's immune system to kill malignant cells.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 2","pages":"16-21"},"PeriodicalIF":0.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TMS: Unlocking the Brain's Power to Transform Surgery-Free Mental Health. 颅磁刺激:释放大脑的力量,改变无需手术的心理健康。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-03-01 DOI: 10.1109/MPULS.2025.3554929
Jim Banks
{"title":"TMS: Unlocking the Brain's Power to Transform Surgery-Free Mental Health.","authors":"Jim Banks","doi":"10.1109/MPULS.2025.3554929","DOIUrl":"10.1109/MPULS.2025.3554929","url":null,"abstract":"<p><p>Transcranial magnetic stimulation (TMS)-is already an established therapy for neurological conditions, including depression and obsessive-compulsive disorder (OCD), as well as being FDA-approved for smoking cessation. Its success in helping patients with treatment-resistant depression through the modulation of activity in specific areas of the brain has established TMS as a safe and effective therapy that could be used to target other areas of the brain and, therefore, treat a vast array of conditions with a neurological component. Trials are under way to assess its use in the treatment of chronic neurological pain, biploar disorder, epilepsy, cognitive decline and so much more. Jim Banks talks to leading researchers in the field to discuss the success of TMS so far, the challenges in designing clinical trials, and the huge scope for potential applications in the years ahead.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 2","pages":"4-8"},"PeriodicalIF":0.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zap the Pain, Skip the Pills With Hypersound: Noninvasive Chronic Pain Treatment With a New Spin on Radio Frequency Microwaves. 用超音波消除疼痛,不用吃药:射频微波的非侵入性慢性疼痛治疗新方法。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-03-01 DOI: 10.1109/MPULS.2025.3554963
Tejas Padliya
{"title":"Zap the Pain, Skip the Pills With Hypersound: Noninvasive Chronic Pain Treatment With a New Spin on Radio Frequency Microwaves.","authors":"Tejas Padliya","doi":"10.1109/MPULS.2025.3554963","DOIUrl":"https://doi.org/10.1109/MPULS.2025.3554963","url":null,"abstract":"<p><p>This article introduces Hypersound Medical's innovative, noninvasive neuromodulation therapy leveraging advanced radio frequency (RF) microwave technology to manage chronic pain without surgical intervention or pharmaceuticals. Traditional pain management methods, including opioids, carry risks such as addiction and significant side effects, highlighting the urgent need for safer alternatives. Hypersound Medical addresses this by utilizing interferential RF microwaves, termed \"hypersound,\" which stimulate neural activity through nonthermal mechanisms involving electrostriction and piezo-sensitive ion channel activation. This targeted stimulation induces natural analgesic responses within the body, providing effective and precise pain relief. The article explores the technology's scientific principles, discusses its clinical and economic benefits, and positions it within the broader context of noninvasive pain management. Hypersound Medical's solution promises enhanced patient outcomes, reduced healthcare costs, and improved accessibility, significantly impacting global health by offering a nonaddictive, accessible pathway to chronic pain relief.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 2","pages":"22-25"},"PeriodicalIF":0.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Revolutionizing an Imaging Technology for Groundbreaking Treatment. 突破性治疗的革命性成像技术。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-03-01 DOI: 10.1109/MPULS.2025.3554977
Leslie Mertz
{"title":"Revolutionizing an Imaging Technology for Groundbreaking Treatment.","authors":"Leslie Mertz","doi":"10.1109/MPULS.2025.3554977","DOIUrl":"https://doi.org/10.1109/MPULS.2025.3554977","url":null,"abstract":"<p><p>Noninvasive ultrasound devices are in development to treat dementia, arthritis, chronic pain and other health conditions.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 2","pages":"9-15"},"PeriodicalIF":0.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-Pulse Transcranial Magnetic Stimulation (sTMS) Technology: eNeura's SAVI Dual Device and Its Role in the Migraine Market. 单脉冲经颅磁刺激(sTMS)技术:eNeura的SAVI双装置及其在偏头痛市场中的作用。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-03-01 DOI: 10.1109/MPULS.2025.3554830
Eric Bohlen
{"title":"Single-Pulse Transcranial Magnetic Stimulation (sTMS) Technology: eNeura's SAVI Dual Device and Its Role in the Migraine Market.","authors":"Eric Bohlen","doi":"10.1109/MPULS.2025.3554830","DOIUrl":"https://doi.org/10.1109/MPULS.2025.3554830","url":null,"abstract":"<p><p>Migraine, a debilitating neurological disorder affecting over 1 billion people worldwide, has long challenged medical science due to its complex pathophysiology and variable treatment responses. Single-pulse transcranial magnetic stimulation (sTMS), a noninvasive central neuromodulation technique, has emerged as a promising therapeutic option. Developed by eNeura Inc., the SAVI Dual device leverages sTMS to provide both acute and preventive migraine relief by targeting hyperactive neural networks in the brain. This article explores the technical underpinnings of SAVI Dual, traces the history of clinical studies that shaped sTMS for neuromodulation, and evaluates its position within the evolving migraine market.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 2","pages":"35-37"},"PeriodicalIF":0.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feel the Precision: Next-Gen Robotic Surgery With Haptic Feedback. 感受精准:新一代机器人手术与触觉反馈。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-01-01 DOI: 10.1109/MPULS.2025.3526484
Janet Rae-Dupree
{"title":"Feel the Precision: Next-Gen Robotic Surgery With Haptic Feedback.","authors":"Janet Rae-Dupree","doi":"10.1109/MPULS.2025.3526484","DOIUrl":"10.1109/MPULS.2025.3526484","url":null,"abstract":"<p><p>While robotic-assisted surgery has opened new frontiers for medical interventions, benefits haven't come without a cost. Surgeons have had to adapt to operating deep within a patient's body without a sense of touch. The technology to restore that sensation-haptic feedback-has been a research goal since robots were first introduced into the operating room. Intuitive Surgical in March 2024 announced that its new da Vinci 5 robotics platform would include integrated force feedback haptic technology-the first FDA-approved system to do so. Using it, surgeons can sense push and pull forces, feel tissue tension, and detect pressure from common tasks such as dissection, retraction, and suturing. But force feedback is only one part of haptics. Finer tactile sensations could open up new possibilities for robotic surgery. Researchers around the globe are developing promising approaches to provide tactile experiences, including at the University of California San Diego, where a team has developed a stretchable, conductive polymer that delivers low-current electrical signals to fingertips.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 1","pages":"12-15"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Swallowable, Remote- Controlled Robot Tours the Stomach, Transmits Live Video. 可吞咽的遥控机器人在胃里漫游,传送实时视频。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-01-01 DOI: 10.1109/MPULS.2025.3526481
Leslie Mertz
{"title":"Swallowable, Remote- Controlled Robot Tours the Stomach, Transmits Live Video.","authors":"Leslie Mertz","doi":"10.1109/MPULS.2025.3526481","DOIUrl":"10.1109/MPULS.2025.3526481","url":null,"abstract":"<p><p>A pill-sized remote-operated vehicle that takes and transmits live video of the inside of a person's stomach could be on the market as early as 2026.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 1","pages":"3-7"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Industry Perspective: The Future of Surgical Robotics-Augmenting a Surgeon's Hands, Eyes, and Brain. 行业展望:外科机器人的未来——增强外科医生的手、眼和脑。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2025-01-01 DOI: 10.1109/MPULS.2025.3526482
Bill Peine, Dan Stoyanov
{"title":"Industry Perspective: The Future of Surgical Robotics-Augmenting a Surgeon's Hands, Eyes, and Brain.","authors":"Bill Peine, Dan Stoyanov","doi":"10.1109/MPULS.2025.3526482","DOIUrl":"10.1109/MPULS.2025.3526482","url":null,"abstract":"<p><p>The future of health care is poised for a transformative shift. Driven by the evolution of surgical robotics, artificial intelligence (AI), and an interconnected ecosystem, health practitioners will be empowered to make procedures more precise, predictable, and personalized. This article explores emerging technologies in surgery that augment a surgeon's hands (robotics), eyes (medical imaging), and brain (AI-driven ecosystems). In robotics, endoluminal approaches and telesurgery are revolutionizing minimally invasive techniques and expanding access to care globally. Advanced visualization using patient specific models and new imaging modalities are enhancing surgical navigation and giving practitioners the ability to see the unseen. AI and data-driven platforms are increasing precision, optimizing clinical workflows, and reducing complications. As we continue to push the boundaries of MedTech innovation, the growing synergy between these technologies will make procedures more safe, more efficient, and more accessible-ultimately redefining surgical standards.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 1","pages":"8-11"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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