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PDCs: A Vital Drop in the Ocean of Funding for Pediatric Devices. PDCs：儿科设备资金汪洋中的重要一滴。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2024-09-01 DOI: 10.1109/MPULS.2024.3443548
Jim Banks
{"title":"PDCs: A Vital Drop in the Ocean of Funding for Pediatric Devices.","authors":"Jim Banks","doi":"10.1109/MPULS.2024.3443548","DOIUrl":"https://doi.org/10.1109/MPULS.2024.3443548","url":null,"abstract":"<p><p>This article is an in-depth examination of the role of pediatric device consortia (PDC) in the development of innovative devices. Looking at the funding model, and at how the challenges that arise in the development of medical devices differ from the development of drug therapies, the article looks at how PDCs can help OEMs with not only funding, but also expertise, regulatory guidance, and more. There is also an examination of some successful devices that have been backed by PDCs, and a comparison with how pediatric devices are funded in Europe to who how the true value of the FDA's PDC grant program.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"15 3","pages":"20-24"},"PeriodicalIF":0.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using AI and ML to Predict Autism Spectrum Disorder. 利用人工智能和 ML 预测自闭症谱系障碍。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2024-09-01 DOI: 10.1109/MPULS.2024.3443489
Leslie Mertz
{"title":"Using AI and ML to Predict Autism Spectrum Disorder.","authors":"Leslie Mertz","doi":"10.1109/MPULS.2024.3443489","DOIUrl":"https://doi.org/10.1109/MPULS.2024.3443489","url":null,"abstract":"<p><p>Autism spectrum disorder is a condition that showcases the potential usefulness of artificial intelligence (AI) and machine learning (ML). This is an area of great need, according to Dennis Wall, Ph.D., professor of pediatrics and biomedical data science at Stanford University in California. \"ASD diagnostics is crying out for a solution that's faster, more equitable, and more quantitative. This is where biomedical data science can really help,\"he said.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"15 3","pages":"11-15"},"PeriodicalIF":0.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design Issues With Pediatric Mechanical Circulatory Support Systems. 儿科机械循环支持系统的设计问题。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2024-09-01 DOI: 10.1109/MPULS.2024.3443492
Jeffrey LaRose
{"title":"Design Issues With Pediatric Mechanical Circulatory Support Systems.","authors":"Jeffrey LaRose","doi":"10.1109/MPULS.2024.3443492","DOIUrl":"https://doi.org/10.1109/MPULS.2024.3443492","url":null,"abstract":"<p><p>Designing a pediatric circulatory support system has several unique challenges related to the small and growing body size. In addition, there is an extra burden on caregivers as these patients can be very active though not yet capable of managing the life sustaining system. This article describes some of the design challenges and offers hope from existing commercial systems being applied to larger pediatric patients.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"15 3","pages":"16-19"},"PeriodicalIF":0.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Designing a Closed-Loop Automated Insulin Delivery System: Simplifying Life for People, Including Children, Living With Type 1 Diabetes. 设计闭环自动胰岛素输送系统：简化 1 型糖尿病患者（包括儿童）的生活。
IF 0.3 4区 医学
IEEE Pulse Pub Date : 2024-09-01 DOI: 10.1109/MPULS.2024.3443488
Eric Benjamin
{"title":"Designing a Closed-Loop Automated Insulin Delivery System: Simplifying Life for People, Including Children, Living With Type 1 Diabetes.","authors":"Eric Benjamin","doi":"10.1109/MPULS.2024.3443488","DOIUrl":"https://doi.org/10.1109/MPULS.2024.3443488","url":null,"abstract":"<p><p>Living with type 1 diabetes is challenging, especially for children and their caregivers. This article describes how Insulet, the global leader in tubeless insulin technology, has continuously innovated Omnipod, a discreet, wearable, waterproof insulin delivery system that simplifies life for people with diabetes.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"15 3","pages":"5-10"},"PeriodicalIF":0.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges and Opportunities for Physiologically Controlled Therapy in Neural Systems 神经系统生理控制疗法的挑战与机遇
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405745
Victoria S. Marks, Rory J. Piper, Joram J. Van Rheede, Moaad Benjaber, Alexander L. Green, Martin T. Tisdall, Timothy J. Denison
{"title":"Challenges and Opportunities for Physiologically Controlled Therapy in Neural Systems","authors":"Victoria S. Marks, Rory J. Piper, Joram J. Van Rheede, Moaad Benjaber, Alexander L. Green, Martin T. Tisdall, Timothy J. Denison","doi":"10.1109/mpuls.2024.3405745","DOIUrl":"https://doi.org/10.1109/mpuls.2024.3405745","url":null,"abstract":"Brain Stimulation Technology for the treatment of neurological disorders is rapidly evolving. With the advent of “bidirectional” systems, such as the Medtronic Percept, which are able to sense from and stimulate the brain simultaneously, there is opportunity to modify stimulation based on changes in brain activity. The utility of such a bidirectional application is exemplified by the success of the NeuroPace responsive neuro stimulation (RNS) device in the reduction of seizures <xref ref-type=\"bibr\" r xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">[1]</xref> and pivotal trials of spinal cord stimulation for chronic leg pain using evoked compound action potentials to facilitate a homeostatic feedback system <xref ref-type=\"bibr\" r xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">[2]</xref>\u0000.","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"16 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141739931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Career Spotlight 早期职业聚焦
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3409110
Nancey Trevanian Tsai
{"title":"Early Career Spotlight","authors":"Nancey Trevanian Tsai","doi":"10.1109/mpuls.2024.3409110","DOIUrl":"https://doi.org/10.1109/mpuls.2024.3409110","url":null,"abstract":"For this issue, we feature Josh Niesen. He is 31/2 years into his position with Medtronic, after spending two summers as an intern during college. Josh earned the B.S. degree in biomedical engineering (BME) from the University of Wisconsin-Madison.","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"95 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141746092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From the Editor 编辑的话
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405688
Mike Hess
{"title":"From the Editor","authors":"Mike Hess","doi":"10.1109/mpuls.2024.3405688","DOIUrl":"https://doi.org/10.1109/mpuls.2024.3405688","url":null,"abstract":"Fifty years ago, one of the most popular American television shows debuted this famous phrase: “We can rebuild him. We have the technology. We can make him better than he was. Better, stronger, faster.” Children and adults alike tuned in to see the latest adventures of Steve Austin, the Six Million Dollar Man, crime-fighting astronaut turned international spy who featured advanced implants that seamlessly blended cyberonic technology through neural interfaces to give him super speed, super strength, super vision, and more.","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"10 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141739929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroengineering—Engineering the Nervous System 神经工程学--神经系统工程学
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405744
Bin He
{"title":"Neuroengineering—Engineering the Nervous System","authors":"Bin He","doi":"10.1109/mpuls.2024.3405744","DOIUrl":"https://doi.org/10.1109/mpuls.2024.3405744","url":null,"abstract":"Neuroengineering, also known as neural engineering, is a rapidly expanding interdisciplinary field that bridges neuroscience and engineering. It encompasses research at the cellular, tissue, and systems levels, and has become a core discipline within biomedical engineering and beyond. By applying engineering principles and methods, neuroengineering studies the nervous system and develops techniques for diagnosing, treating, and rehabilitating neurological disorders. This field includes neural sensing, signal processing, interfacing, modulation, computation, imaging, and device development, among others. Over the past decade, significant progress has been made in neuroengineering, or neurotechnology, which focuses more on neural devices or tools. This progress is partly attributable to initiatives such as the Brain Research through Advancing Innovative Neurotechnologies\u0000<xref ref-type=\"fn\" r xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">1</xref> (BRAIN) Initiative in the U.S. and similar efforts worldwide.","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"43 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141746036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping the Impossible: Europe’s Human Brain Project Comes of Age 绘制不可能的地图：欧洲的人脑项目进入成熟期
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405749
Jim Banks
{"title":"Mapping the Impossible: Europe’s Human Brain Project Comes of Age","authors":"Jim Banks","doi":"10.1109/mpuls.2024.3405749","DOIUrl":"https://doi.org/10.1109/mpuls.2024.3405749","url":null,"abstract":"Back in 2021, a paper recently published in The Lancet <xref ref-type=\"bibr\" r xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" xmlns:xlink=\"http://www.w3.org/1999/xlink\">[1]</xref> defined the impact on human life of disorders affecting the nervous system. Neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment, were among 37 conditions reviewed. The results were chilling.","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"44 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141739930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dismantling Descartes 拆解笛卡尔
IF 0.6 4区 医学
IEEE Pulse Pub Date : 2024-07-18 DOI: 10.1109/mpuls.2024.3405748
Nancey Trevanian Tsai
{"title":"Dismantling Descartes","authors":"Nancey Trevanian Tsai","doi":"10.1109/mpuls.2024.3405748","DOIUrl":"https://doi.org/10.1109/mpuls.2024.3405748","url":null,"abstract":"In the 1999 movie The Matrix, Neo emerges from a vat of jelly shortly after taking the Red Pill. It suggested that there is a separation between the mind and the body and that the brain as the master driver of experiences could be hijacked to keep the body subjugated until its useful life—under the control of an outside force—had terminated. Likewise, students taking philosophy are often introduced to Rene Descartes’ “Cogito ergo sum,” which translates as, “I think, therefore I am.” The central idea of the discourse is that the mind is proof of existence, even if the body cannot be verified. Indeed, many of us seem to live one life inside our heads while our body moves through a different, physical world. By way of introducing the mind-body dichotomy, it also suggested an unintended hierarchy. Do any of us really believe we are mere “brain in a vat”?","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":"19 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141739932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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