Journal of Cardiovascular Computed Tomography最新文献

{"title":"Initial Insights Into CT Myocardial Perfusion Imaging Using Photon-counting Detector Technology","authors":"F. Pontana, C. Gkizas, A. Rodriguez Musso, B. Longere","doi":"10.1016/j.jcct.2024.12.067","DOIUrl":"10.1016/j.jcct.2024.12.067","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Pages S25-S26"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AUtomated Classification of Coronary LEsions FROm Coronary Computed TOmography Angiography Scans With an Updated Deep Learning Model: Alert Study","authors":"V. Verpalen, C. Coerkamp","doi":"10.1016/j.jcct.2024.12.014","DOIUrl":"10.1016/j.jcct.2024.12.014","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Page S5"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved diagnostic accuracy of vessel-specific myocardial ischemia by coronary computed tomography angiography (CCTA)","authors":"Marta Belmonte ,&nbsp;Pasquale Paolisso ,&nbsp;Emanuele Gallinoro ,&nbsp;Dario Tino Bertolone ,&nbsp;Attilio Leone ,&nbsp;Giuseppe Esposito ,&nbsp;Serena Caglioni ,&nbsp;Michele Mattia Viscusi ,&nbsp;Konstantinos Bermpeis ,&nbsp;Tatyana Storozhenko ,&nbsp;Eric Wyffels ,&nbsp;Joseph Bartunek ,&nbsp;Jeroen Sonck ,&nbsp;Carlos Collet ,&nbsp;Daniele Andreini ,&nbsp;Marc Vanderheyden ,&nbsp;Martin Penicka ,&nbsp;Emanuele Barbato","doi":"10.1016/j.jcct.2024.09.015","DOIUrl":"10.1016/j.jcct.2024.09.015","url":null,"abstract":"<div><h3>Background</h3><div>Discrepancies between stenosis severity assessed at coronary computed tomography angiography (CCTA) and ischemia might depend on vessel type. Coronary plaque features are associated with ischemia. Thus, we evaluated the vessel-specific correlation of CCTA-derived diameter stenosis (DS) and invasive fractional flow reserve (FFR) and explored whether integrating morphological plaque features stratified by vessel might increase the predictive yield in identifying vessel-specific ischemia.</div></div><div><h3>Methods</h3><div>Observational cohort study including patients undergoing CCTA for suspected coronary artery disease, with at least one vessel with DS ​≥ ​50 ​% at CCTA, undergoing invasive coronary angiography and FFR. Plaque analysis was performed using validated semi-automated software. Coronary vessels were stratified in left anterior descending (LAD), left circumflex (LCX), and right coronary artery (RCA). Per vessel independent predictors of ischemia among CCTA-derived anatomical and morphologic plaque features were tested at univariable and multivariable logistic regression analysis. The best cut-off to predict ischemia was determined by Youden's index. Ischemia was defined by FFR≤0.80.</div></div><div><h3>Results</h3><div>The study population consisted of 192 patients, of whom 224 vessels (61 ​% LAD, 19 ​% LCX, 20 ​% RCA) had lesions with DS ​≥ ​50 ​% interrogated by FFR. Despite similar DS, the rate of FFR≤0.80 was higher in the LAD compared to LCX and RCA (67.2 ​% vs 43.2 ​% and 44.2 ​%, respectively, p ​= ​0.018). A significant correlation between DS and FFR was observed only in LAD (p ​= ​0.003). At multivariable analysis stratified by vessel, the vessel-specific independent predictors of positive FFR were percent atheroma volume (threshold&gt;17 ​%) for LAD, non-calcified plaque volume (threshold &gt;130 ​mm³) for LCX, and lumen volume (threshold &lt;844 ​mm³) for RCA. Integrating DS and vessel-specific morphological plaque features significantly increased the predictive yield for ischemia compared to DS alone (AUC ranging from 0.51 to 0.63 to 0.76–0.80).</div></div><div><h3>Conclusions</h3><div>Integrating DS and vessel-specific morphological plaque features significantly increased the predictive yield for vessel-specific ischemia compared to DS alone, potentially improving patients’ referral to the catheterization laboratory.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Pages 17-25"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of coronary inflammation with plaque vulnerability and fractional flow reserve in coronary artery disease","authors":"You-Jung Choi ,&nbsp;Seokhun Yang ,&nbsp;Henry West ,&nbsp;Pete Tomlins ,&nbsp;Masahiro Hoshino ,&nbsp;Tadashi Murai ,&nbsp;Doyeon Hwang ,&nbsp;Eun-Seok Shin ,&nbsp;Joon-Hyung Doh ,&nbsp;Chang-Wook Nam ,&nbsp;Jianan Wang ,&nbsp;Hitoshi Matsuo ,&nbsp;Tsunekazu Kakuta ,&nbsp;Charalambos Antoniades ,&nbsp;Bon-Kwon Koo","doi":"10.1016/j.jcct.2024.10.013","DOIUrl":"10.1016/j.jcct.2024.10.013","url":null,"abstract":"<div><h3>Background</h3><div>The fat attenuation index (FAI) measured using coronary computed tomography angiography (CCTA) enables the direct evaluation of pericoronary adipose tissue composition and vascular inflammation. We aimed to investigate the association of fractional flow reserve (FFR) and plaque vulnerability with coronary inflammation.</div></div><div><h3>Methods</h3><div>Patients with suspected coronary artery disease (CAD) who underwent CCTA and invasive FFR measurements within 90-day were included. A cloud-based medical device, CaRi-Heart, serves as a surrogate tool for evaluating coronary inflammation based on FAI by analyzing CCTA images. The correlations between CCTA-defined plaque characteristics, invasive coronary angiographic and physiologic assessments, and CaRi-Heart risk were analyzed. The primary endpoint was the patient-oriented composite outcome (POCO) consisting of all-cause death, any myocardial infarction, and any revascularization.</div></div><div><h3>Results</h3><div>A total of 564 patients (median age 67.0 years; 75.4 ​% men) were included. There were no significant differences in quantitative and qualitative plaque characteristics or FFR between the high- and low-CaRi-Heart risk groups (i.e., ≥5 ​% and &lt;5 ​%). During the median follow-up of 3.2 years [1.13–4.73 years], CaRi-Heart risk ≥5 ​% was associated with a significantly higher rate of POCO compared to CaRi-Heart risk &lt;5 ​% (0.9 ​% vs. 10.1 ​%, <em>P</em> ​= ​0.037). The CaRi-Heart risk was an independent predictor of POCO as a continuous (adjusted HR 1.016, 95 ​% CI 1.005–0.027, <em>P</em> ​= ​0.004) and categorical variable (CaRi-Heart risk ≥5 ​%, adjusted HR 2.949, 95 ​% CI 1.182–7.360, <em>P</em> ​= ​0.021), regardless of high-risk plaque characteristics and FFR.</div></div><div><h3>Conclusion</h3><div>Coronary inflammation risk assessed using CaRi-Heart risk provides independent prognostic information regardless of plaque vulnerability and physiologic stenosis in patients with CAD.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Pages 32-39"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness of ultrahigh-resolution photon-counting detector coronary CT angiography for the evaluation of stable chest pain","authors":"Milán Vecsey-Nagy ,&nbsp;Tilman Emrich ,&nbsp;Giuseppe Tremamunno ,&nbsp;Dmitrij Kravchenko ,&nbsp;Muhammad Taha Hagar ,&nbsp;Gerald S. Laux ,&nbsp;U. Joseph Schoepf ,&nbsp;Jim O'Doherty ,&nbsp;Melinda Boussoussou ,&nbsp;Bálint Szilveszter ,&nbsp;Pál Maurovich-Horvat ,&nbsp;Thomas Kroencke ,&nbsp;Ismail Mikdat Kabakus ,&nbsp;Pal Spruill Suranyi ,&nbsp;Akos Varga-Szemes ,&nbsp;Josua A. Decker","doi":"10.1016/j.jcct.2024.10.011","DOIUrl":"10.1016/j.jcct.2024.10.011","url":null,"abstract":"<div><h3>Background</h3><div>The increased specificity of ultrahigh-resolution (UHR) photon-counting detector (PCD)-CT over energy-integrating detector (EID)-CT for coronary CT angiography (CCTA) could defer unwarranted downstream tests. The objective of the study was to simulate the cost-effectiveness of UHR CCTA in stable chest pain patients with coronary calcifications.</div></div><div><h3>Methods</h3><div>A decision and simulation model was developed using Monte Carlo simulations with 1000 bootstrap resamples to estimate the costs associated with PCD-CT in lieu of EID-CT for CCTA and the referral for subsequent testing. The model was constructed using the diagnostic accuracy metrics of 55 coronary lesions in patients who underwent CCTA on both CT systems and subsequent invasive coronary angiography (ICA). Sensitivity and specificity were defined for each Coronary Artery Disease Reporting and Data System category. The aggregate healthcare expenditures were derived from the hospital billing system.</div></div><div><h3>Results</h3><div>Assuming a projected cohort of 15,000 patients over the lifetime of the PCD-CT, its implementation resulted in a 18.9 ​% reduction in the number of functional follow-up tests (6330.3 ​± ​59.5 vs. 5135.7 ​± ​60.6, p ​&lt; ​0.001), a 6.0 ​% reduction in performed ICAs (1447.7 ​± ​36.2 vs. 1360.2 ​± ​34.7, p ​&lt; ​0.001), and a 9.4 ​% decrease in major procedure-related complications. Over a 10-year expected life expectancy, PCD-CT led to an average cost saving of $794.50 ​± ​18.50 per patient and an overall cost difference of $11,917,500 ​± ​4,350,169.</div></div><div><h3>Conclusions</h3><div>PCD-CT has the potential to reduce the financial burden on healthcare systems and procedure-related complications for stable chest pain patients with coronary calcification when compared to EID-CT.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Pages 106-112"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Special Focus Issue on Business Aspects of Cardiac CT","authors":"Ahmad Slim Guest Editor","doi":"10.1016/j.jcct.2024.12.087","DOIUrl":"10.1016/j.jcct.2024.12.087","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Page 88"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modern CT detector technology and innovations in image reconstruction enhance cardiovascular CT","authors":"Juan Gaztanaga,&nbsp;Juan Lopez-Mattei","doi":"10.1016/j.jcct.2024.12.090","DOIUrl":"10.1016/j.jcct.2024.12.090","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Pages 72-73"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The RUCkus around plaque","authors":"Tyler Coombes,&nbsp;Shone Almeida,&nbsp;Mathew Budoff,&nbsp;Kashif Shaikh","doi":"10.1016/j.jcct.2024.12.002","DOIUrl":"10.1016/j.jcct.2024.12.002","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Pages 159-161"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast Cardiac Chest Computed Tomography Utility to Differentiate Left Atrium Artifact Seeing During a Routine Evaluation of Post Implanatation of a Left Atrium Appendage Occluder Via Transesopahageal Echocardiography: A Complex Clinical Dilema","authors":"J. Mendiolaza","doi":"10.1016/j.jcct.2024.12.065","DOIUrl":"10.1016/j.jcct.2024.12.065","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Pages S24-S25"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Coronary Ct Angiography: Motion Compensated Reconstruction Improves Image Quality and Diagnostic Interpretability","authors":"P. Tetteroo ,&nbsp;N. van der Werf ,&nbsp;I. Bax ,&nbsp;M. Vembar ,&nbsp;T. Leiner ,&nbsp;P. de Jong ,&nbsp;B. Velthuis ,&nbsp;D. Suchá","doi":"10.1016/j.jcct.2024.12.054","DOIUrl":"10.1016/j.jcct.2024.12.054","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"19 1","pages":"Page S20"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143428820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}