{"title":"Evaluating the CT-STEMI study: The controversy over CCT and CMR for post-STEMI prognosis","authors":"Weikai Dong","doi":"10.1016/j.jcct.2025.08.007","DOIUrl":"10.1016/j.jcct.2025.08.007","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"20 2","pages":"Pages 196-197"},"PeriodicalIF":5.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susann Skoog , Christos Pagonis , Mårten Sandstedt , Lilian Henriksson , Håkan Gustafsson , Anders Persson , Erik Tesselaar
{"title":"Diagnostic accuracy of energy-integrating and standard-resolution photon counting detector CT for coronary artery stenosis grading in CCTA: A comparative study","authors":"Susann Skoog , Christos Pagonis , Mårten Sandstedt , Lilian Henriksson , Håkan Gustafsson , Anders Persson , Erik Tesselaar","doi":"10.1016/j.jcct.2026.01.003","DOIUrl":"10.1016/j.jcct.2026.01.003","url":null,"abstract":"<div><h3>Background</h3><div>Coronary CT angiography (CCTA) is a key non-invasive tool for evaluating coronary artery disease (CAD). While energy-integrating detector CT (EID-CT) offers high negative predictive value (NPV), its positive predictive value (PPV) is limited in heavily calcified vessels. Photon-counting detector CT (PCD-CT), with higher spatial resolution and reduced blooming, may enhance diagnostic performance. Current PCD-CT systems provide both standard-resolution (SR) and ultra-high-resolution (UHR) modes, but the clinical impact of these modes remains under investigation.</div></div><div><h3>Objectives</h3><div>To compare the diagnostic accuracy and image quality of SR-PCD-CT versus EID-CT in quantifying coronary stenosis, using quantitative coronary angiography (QCA) as reference.</div></div><div><h3>Materials and methods</h3><div>In this prospective, single-centre study, 21 patients (5 women, mean age 71.5 years) with suspected CAD underwent CCTA with both EID-CT and SR-PCD-CT prior to QCA. A total of 301 coronary segments were assessed for stenosis severity, with ≥50 % stenosis deemed significant. Image quality was graded using a 5-point scale.</div></div><div><h3>Results</h3><div>No significant differences in percentage diameter stenosis (%DS) were found between imaging techniques (p = 0.20). Both EID-CT and SR-PCD-CT showed good agreement with QCA (AUC: PCD-CT 0.89, EID-CT 0.86). Specificity and NPV were high for both; sensitivity and PPV were moderate. SR-PCD-CT yielded higher image quality compared to EID-CT (<em>p</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>In standard resolution mode, PCD-CT offers excellent image quality for quantifying coronary stenosis at comparable diagnostic accuracy compared to EID-CT.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"20 2","pages":"Pages 157-163"},"PeriodicalIF":5.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Table of contents-4C","authors":"","doi":"10.1016/S1934-5925(26)00067-5","DOIUrl":"10.1016/S1934-5925(26)00067-5","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"20 2","pages":"Pages A3-A7"},"PeriodicalIF":5.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147707069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Images to Insight: The Evolving Role of the Cardiovascular Imager","authors":"Kavitha Chinnaiyan (MD, MSCCT)","doi":"10.1016/j.jcct.2026.03.005","DOIUrl":"10.1016/j.jcct.2026.03.005","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"20 2","pages":"Pages 111-112"},"PeriodicalIF":5.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147706192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyung An Kim , Hae-Ok Jung , Mi-Jeong Kim , So-Young Lee , Dong-Hyeon Lee , Donghee Han , Hyuk-Jae Chang , Su-Yeon Choi , Jidong Sung , Eun Ju Chun
{"title":"The role of serum phosphate and calcium levels in coronary artery calcification progression: A multicenter, longitudinal cohort study","authors":"Kyung An Kim , Hae-Ok Jung , Mi-Jeong Kim , So-Young Lee , Dong-Hyeon Lee , Donghee Han , Hyuk-Jae Chang , Su-Yeon Choi , Jidong Sung , Eun Ju Chun","doi":"10.1016/j.jcct.2025.10.012","DOIUrl":"10.1016/j.jcct.2025.10.012","url":null,"abstract":"<div><h3>Background</h3><div>Higher serum phosphate levels are associated with cardiovascular diseases, including coronary artery calcification (CAC). However, there exists limited evidence supporting a causal relationship between phosphate levels and CAC progression.</div></div><div><h3>Methods</h3><div>Using the KOrea Initiatives on Coronary Artery Calcification (KOICA) registry, we assessed CAC using the CAC score assessed by cardiac computed tomography (CT) in participants with normal serum phosphate (2.5–4.5 mg/dL) and calcium levels and without renal dysfunction (estimated glomerular filtration rate ≥60 mL/min/1.73 m<sup>2</sup>). The effect of serum phosphate and calcium levels on the prevalence and severity of CAC at baseline and the longitudinal progression of CAC were analyzed using multivariable regression models.</div></div><div><h3>Results</h3><div>A total of 12,251 individuals and 31,251 CT scans were selected for analysis, with a median follow-up duration of 3.5 (interquartile range 2.1–5.1) years. In the baseline cross-sectional analysis, serum phosphate levels were associated with higher CAC prevalence (OR per 1 mg/dL increase, 1.09, 95 % CI 1.06–1.11, <em>p</em> < 0.001) and CAC severity (β-coefficient per 1 mg/dL increase, 0.35, 95 % CI 0.25, 0.45, <em>p</em> < 0.001). In longitudinal analysis, serum phosphate levels also showed a significant association with higher probability of CAC progression (HR per 1 mg/dL increase, 1.19, 95 % CI, 1.06, 1.32; <em>p</em> < 0.001) and faster CAC score progression (β coefficient per 1 mg/dL, 2.54 × 10<sup>−2</sup>; 95 % CI, 1.43 × 10<sup>−2</sup>–3.67 × 10<sup>−2</sup>; <em>p</em> < 0.001).</div></div><div><h3>Conclusion</h3><div>Higher serum phosphate levels, even within the normal range, are associated with faster CAC progression. Further studies are needed to demonstrate the possibility of slowing CAC development through the regulation of calcium-phosphate metabolism.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"20 2","pages":"Pages 113-120"},"PeriodicalIF":5.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145369241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}