Journal of Cardiovascular Computed Tomography最新文献

{"title":"Computed tomography coronary angiography assessment of left main coronary artery stenosis severity","authors":"Udit Thakur ,&nbsp;Jason Nogic ,&nbsp;Andrea Comella ,&nbsp;Nitesh Nerlekar ,&nbsp;Jasmine Chan ,&nbsp;Timothy Abrahams ,&nbsp;Michael Michail ,&nbsp;Adam Nelson ,&nbsp;Damini Dey ,&nbsp;Brian Ko ,&nbsp;Sujith Seneviratne ,&nbsp;Adam J. Brown","doi":"10.1016/j.jcct.2024.07.005","DOIUrl":"10.1016/j.jcct.2024.07.005","url":null,"abstract":"<div><h3>Background</h3><div>Angiographic assessment of left main coronary artery (LMCA) stenosis severity can be unreliable. In cases of ambiguity, intravascular ultrasound (IVUS) can be utilised with a minimal lumen area (MLA) of ≥6 ​mm² an accepted threshold for safe deferral of revascularization. We sought to assess whether quantitative computer tomography coronary angiography (CTCA) measures could assist clinicians making LMCA revascularization decisions when compared with IVUS as gold standard.</div></div><div><h3>Methods</h3><div>Consecutive patients undergoing IVUS assessment of angiographically intermediate LMCA stenosis were included. All patients had undergone 320-slice CTCA &lt;90 days prior to IVUS imaging. Offline quantitative assessment of IVUS- and CT-derived measures were undertaken with the cohort divided into those with significant (s-LMCA) versus non-significant (ns-LMCA) disease using the accepted IVUS threshold.</div></div><div><h3>Results</h3><div>Fifty-eight patients were included, with no difference in mean age (61.5 ​± ​12.2 vs. 59.7 ​± ​11.9 years, <em>p</em> ​= ​0.57), diabetic status (24.2% vs 16.0%, <em>p</em> ​= ​0.44) or other baseline demographics between groups. Patients with ns-LMCA had larger CT luminal area (8.64 ​± ​3.91 vs. 5.41 ​± ​1.54 ​mm², <em>p</em> ​&lt; ​0.001), larger minimal lumen diameter (MLD) (3.25 ​± ​0.74 vs. 2.56 ​± ​0.38 ​mm, <em>p</em> ​&lt; ​0.001) and lower area stenosis (45.74 ​± ​18.10 vs. 60.93 ​± ​14.68%, <em>p</em> ​= ​0.001). There was a significant positive correlation between CTCA and IVUS MLA (r ​= ​0.68, p ​&lt; ​0.001) and MLD (r ​= ​0.67, <em>p</em> ​&lt; ​0.001). ROC analysis demonstrated CTCA MLA cut-off &lt;8.29 ​mm² provides the greatest negative predictive value and sensitivity in predicting the presence of significant LMCA disease.</div></div><div><h3>Conclusion</h3><div>CTCA derived MLA and MLD have a strong correlation with IVUS. A CTCA derived MLA cut-off &lt;8.29 ​mm² showed greatest clinical utility for predicting the need for further assessment, based on IVUS gold standard.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 543-550"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141725414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in total plaque burden between plaque rupture and plaque erosion: A combined computed tomography angiography and optical coherence tomography study","authors":"Takayuki Niida ,&nbsp;Eisuke Usui ,&nbsp;Keishi Suzuki ,&nbsp;Daisuke Kinoshita ,&nbsp;Haruhito Yuki ,&nbsp;Daichi Fujimoto ,&nbsp;Marco Covani ,&nbsp;Damini Dey ,&nbsp;Hang Lee ,&nbsp;Iris McNulty ,&nbsp;Maros Ferencik ,&nbsp;Taishi Yonetsu ,&nbsp;Tsunekazu Kakuta ,&nbsp;Ik-Kyung Jang","doi":"10.1016/j.jcct.2024.09.007","DOIUrl":"10.1016/j.jcct.2024.09.007","url":null,"abstract":"<div><h3>Backgrounds</h3><div>Coronary computed tomography angiography (CTA) allows for the assessment of atherosclerotic plaque burden across the entire coronary vasculature. No studies have examined the relationship between the underlying pathology of the culprit lesion and total plaque burden in patients with acute coronary syndromes. The aim of this study was to compare the total plaque burden between patients with plaque rupture versus plaque erosion.</div></div><div><h3>Methods</h3><div>A total of 232 patients who presented with their first non-ST-segment elevation acute coronary syndrome and underwent both CTA and optical coherence tomography imaging before intervention were selected. Quantitative analysis was performed using semi-automated software (Autoplaque version 3.0, Cedars-Sinai Medical Center). An attenuation of &lt;30 Hounsfield units defined low-density non-calcified plaque (LDNCP). All 3 vessels were assessed using the modified 17-segment American Heart Association model for coronary segment classification.</div></div><div><h3>Results</h3><div>Among 232 patients, 125 (53.9%) had plaque rupture and 107 (46.1%) had plaque erosion. Total plaque burden (48.2 [39.8–54.9] % vs. 44.1 [38.6–50.0] %, P ​= ​0.006), total non-calcified plaque (NCP) burden (46.6 [39.1–53.3] % vs. 43.0 [37.6–49.2] %, P ​= ​0.013), total LDNCP burden (2.3 [1.4–3.0] % vs. 1.7 [1.2–2.6] %, P ​= ​0.016), and total calcified plaque (CP) burden (0.8 [0.1–1.6] % vs. 0.4 [0.0–1.4] %, P ​= ​0.047) were significantly greater in patients with culprit plaque rupture than in those with culprit plaque erosion.</div></div><div><h3>Conclusion</h3><div>Patients with plaque rupture, compared with those with plaque erosion, had a greater total plaque burden, NCP burden, LDNCP burden, and CP burden.</div></div><div><h3>Clinical trial registration</h3><div>URL: <span><span>https://www.clinicaltrials.gov</span><svg><path></path></svg></span>; Unique identifier: NCT04523194.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 568-574"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interscan reproducibility of computed tomography derived coronary plaque volume measurements","authors":"Nadia Iraqi ,&nbsp;Martin Bødtker Mortensen ,&nbsp;Niels Peter Rønnow Sand ,&nbsp;Martin Busk ,&nbsp;Erik Lerkevang Grove ,&nbsp;Damini Dey ,&nbsp;Kamilla Bech Pedersen ,&nbsp;Helle Kanstrup ,&nbsp;Alexandra Uglebjerg Pedersen ,&nbsp;Kristian Tækker Madsen MD ,&nbsp;Erik Parner ,&nbsp;Jesper Møller Jensen ,&nbsp;Bjarne Linde Nørgaard","doi":"10.1016/j.jcct.2024.09.009","DOIUrl":"10.1016/j.jcct.2024.09.009","url":null,"abstract":"<div><h3>Background</h3><div>Coronary computed tomography angiography (CCTA) enables detailed quantification and characterization of coronary atherosclerotic plaques, offering diagnostic and prognostic value. Interscan reproducibility studies on plaque volume measurements are limited. This study aims to assess the interscan reproducibility of coronary plaque quantification and the implications of clinical and technical characteristics on interscan reproducibility.</div></div><div><h3>Methods</h3><div>CCTA was performed twice in 101 patients with known coronary artery disease at a 1-h interval. The scans were conducted using identical CCTA acquisition protocols. Coronary plaque volumes were quantified using a semi-automated software and performed on a per-lesion, per-vessel, and per-patient level.</div></div><div><h3>Results</h3><div>Median plaque volumes were comparable between the first and second CCTA scan. Interscan correlation was high for total plaque (TP), non-calcified plaque (NCP), and calcified plaque (CP) across all analyses (Pearson's coefficient 0.93–0.99), but lower for low-density non-calcified plaque (LD-NCP) volume measurements (Pearson's coefficient 0.74–0.77). Bland-Altman analyses demonstrated higher interscan agreement on a per-patient level compared to on per-vessel and per-lesion level. Interscan reproducibility on CP volumes was affected by CT image quality with narrower LoA in scans with the highest image quality score (p ​= ​0.003), or lowest image reconstructive iteration level (p ​&lt; ​0.001). Limits of agreement were significantly narrower for TP, NCP, and CP volumes in LAD-lesions and vessels compared to non-LAD lesions and vessels (p ​≤ ​0.001).</div></div><div><h3>Conclusion</h3><div>Overall reproducibility of repeated CCTA derived plaque measurements by a semi-automated software was modest, and was influenced by image quality, image reconstruction settings, and lesion location.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 583-592"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First reported Intra-cavitary right-to-left coronary artery collateral in the context of D-TGA","authors":"Claire F. Woodworth ,&nbsp;Ryan C. Yee ,&nbsp;Tim Leiner","doi":"10.1016/j.jcct.2024.09.005","DOIUrl":"10.1016/j.jcct.2024.09.005","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages e18-e20"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac symptomatology and coronary artery disease. A clinical conundrum","authors":"Ruurt A. Jukema,&nbsp;Yvemarie BO. Somsen,&nbsp;Roel Hoek,&nbsp;Nick S. Nurmohamed,&nbsp;Roel S. Driessen,&nbsp;Pieter G. Raijmakers,&nbsp;Pim van der Harst,&nbsp;Maarten J. Cramer,&nbsp;Paul Knaapen,&nbsp;Ibrahim Danad","doi":"10.1016/j.jcct.2024.09.004","DOIUrl":"10.1016/j.jcct.2024.09.004","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 618-619"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy-integrating detector based ultra-high-resolution CT with deep learning reconstruction for the assessment of calcified lesions in coronary artery disease","authors":"Misato Sone ,&nbsp;Makoto Orii ,&nbsp;Yoshitaka Ota ,&nbsp;Takuya Chiba ,&nbsp;Joanne D. Schuijf ,&nbsp;Naruomi Akino ,&nbsp;Kunihiro Yoshioka","doi":"10.1016/j.jcct.2024.09.014","DOIUrl":"10.1016/j.jcct.2024.09.014","url":null,"abstract":"<div><h3>Background</h3><div>The aim of this study to compare of the image quality of calcified lesions in coronary artery disease between deep learning reconstruction (DLR) and model-based iterative reconstruction (MBIR) on energy-integrating detector (EID) based ultra-high-resolution CT (UHRCT).</div></div><div><h3>Methods</h3><div>We performed a phantom study on EID-based UHRCT using a dedicated insert for calcifications and obtained the derivative values for DLR and MBIR. In the clinical study, the derivative values were compared between DLR and MBIR across 73 calcified lesions in 62 patients. Edge sharpness of calcifications and contrast resolution at the coronary lumen side were quantified by the maximum and minimum derivative values. Two radiologists independently analyzed image quality of the calcified lesions using a 5-point Likert scale.</div></div><div><h3>Results</h3><div>In the phantom study, the edge sharpness of the 3-mm calcifications on DLR (median, 924 HU/mm; IQR, 580–1741 HU/mm) was significantly higher than on MBIR (median, 835 HU/mm; IQR, 484–1552; p ​&lt; ​0.001). In the clinical study, the image quality of the calcified lesions was significantly better on DLR with significantly reduced reconstruction time (p ​&lt; ​0.001). The contrast resolution at the coronary lumen side on DLR (median, −99.1 HU/mm; IQR, −209 to −34.3 HU/mm) was significantly higher than on MBIR (median, −41.8 HU/mm; IQR, −121 to 22.3 HU/mm, p ​&lt; ​0.001) although the edge sharpness of calcifications was similar between DLR and MBIR (p ​= ​0.794) in the clinical setting.</div></div><div><h3>Conclusion</h3><div>EID-based UHRCT reconstructed using DLR represents better image quality of calcified lesions in coronary artery disease compared with MBIR, with significantly reduced reconstruction time.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 575-582"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Truncus arteriosus with double aortic arch: A rare case in an unrepaired pregnant patient","authors":"Liya Dai ,&nbsp;Chenhui Zhou ,&nbsp;Yanhua Huang ,&nbsp;Fanghong Chen ,&nbsp;Chenying Lu","doi":"10.1016/j.jcct.2024.07.011","DOIUrl":"10.1016/j.jcct.2024.07.011","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages e15-e17"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to ‘Computed tomography-derived normative values and z-scores of the pulmonary valve annulus and sino-tubular junction in the pediatric population’ [J Cardiovasc Comput Tomogr 18 (2024) 489–493]","authors":"Natalie Soszyn,&nbsp;Michael Shorofsky,&nbsp;Salvador Rodriguez Franco,&nbsp;Jenny E. Zablah,&nbsp;Gareth J. Morgan","doi":"10.1016/j.jcct.2024.10.005","DOIUrl":"10.1016/j.jcct.2024.10.005","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Page 620"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building the bridges – Collaborative spirit of our society","authors":"Maros Ferencik","doi":"10.1016/j.jcct.2024.10.007","DOIUrl":"10.1016/j.jcct.2024.10.007","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 517-518"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Table of contents-4C","authors":"","doi":"10.1016/S1934-5925(24)00468-4","DOIUrl":"10.1016/S1934-5925(24)00468-4","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages A3-A7"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}