Thomas Sartoretti, Lukas J. Moser, Stéphane Rusek, Filippo Civaia, Philippe Rossi, Alessandro Candreva, Robert Manka, Matthias Eberhard, Hatem Alkadhi, Victor Mergen
{"title":"Photon-counting detector coronary CT angiography: Defining the optimal monoenergetic level for grading of calcified coronary stenosis","authors":"Thomas Sartoretti, Lukas J. Moser, Stéphane Rusek, Filippo Civaia, Philippe Rossi, Alessandro Candreva, Robert Manka, Matthias Eberhard, Hatem Alkadhi, Victor Mergen","doi":"10.1016/j.jcct.2024.06.007","DOIUrl":"10.1016/j.jcct.2024.06.007","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 616-617"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141322200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Getting older by a decade after preeclampsia","authors":"Amelie Paquin, Thais Coutinho","doi":"10.1016/j.jcct.2024.08.007","DOIUrl":"10.1016/j.jcct.2024.08.007","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 541-542"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Verhemel , Rutger-Jan Nuis , Mark van den Dorpel , Rik Adrichem , Mauricio Felippi de Sá Marchi , Alexander Hirsch , Joost Daemen , Ricardo P.J. Budde , Nicolas M. Van Mieghem
{"title":"Computed tomography to predict pacemaker need after transcatheter aortic valve replacement","authors":"Sarah Verhemel , Rutger-Jan Nuis , Mark van den Dorpel , Rik Adrichem , Mauricio Felippi de Sá Marchi , Alexander Hirsch , Joost Daemen , Ricardo P.J. Budde , Nicolas M. Van Mieghem","doi":"10.1016/j.jcct.2024.08.009","DOIUrl":"10.1016/j.jcct.2024.08.009","url":null,"abstract":"<div><div>Transcatheter aortic valve replacement (TAVR) is preferred therapy for elderly patients with severe aortic stenosis (AS) and increasingly used in younger patient populations with good safety and efficacy outcomes. However, cardiac conduction abnormalities remain a frequent complication after TAVR ranging from relative benign interventriculair conduction delays to prognostically relevant left bundle branch block and complete atrio-ventricular (AV) block requiring permanent pacemaker implantation (PPI). Although clinical, procedural and electrocardiographic factors have been identified as predictors of this complication, there is a need for advanced strategies to control the burden of conduction defects particularly as TAVR shifts towards younger populations. This state of the art review highlights the value of ECG-synchronized computed tomographic angiography (CTA) evaluation of the aortic root to better understand and manage conduction problems post-TAVR. An update on CTA derived anatomic features related to conduction issues is provided and complemented with computational framework modelling. This CTA-derived 3-dimensional anatomical reconstruction tool generates patient-specific TAVR simulations enabling operators to adapt procedural strategy and implantation technique to mitigate conduction abnormality risks.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 597-608"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coronary computed tomography angiography for the diagnosis of significant left main coronary artery disease","authors":"Carlos M. Campos, Hector M. Garcia-Garcia","doi":"10.1016/j.jcct.2024.10.012","DOIUrl":"10.1016/j.jcct.2024.10.012","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 551-552"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miho Fukui, Paul Sorajja, David WM. Muller, Evan Walser-Kuntz, Larissa I. Stanberry, Vasilis C. Babaliaros, Vinod H. Thourani, Nicolas Dumonteil, Darren Walters, Gry Dahle, Paul A. Grayburn, Marvin H. Eng, Michael L. Chuang, Benjamin Sun, Philipp Blanke, Alison Duncan, João L. Cavalcante
{"title":"Biventricular reverse-remodeling after transcatheter mitral valve replacement with the Tendyne™ system","authors":"Miho Fukui, Paul Sorajja, David WM. Muller, Evan Walser-Kuntz, Larissa I. Stanberry, Vasilis C. Babaliaros, Vinod H. Thourani, Nicolas Dumonteil, Darren Walters, Gry Dahle, Paul A. Grayburn, Marvin H. Eng, Michael L. Chuang, Benjamin Sun, Philipp Blanke, Alison Duncan, João L. Cavalcante","doi":"10.1016/j.jcct.2024.06.003","DOIUrl":"10.1016/j.jcct.2024.06.003","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 613-615"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141422209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexa E. Golbus , John L. Schuzer , Shirley F. Rollison , Kathie C. Bronson , Scott P. Baute , Marcus Y. Chen
{"title":"3D Landmark scout imaging accurately assesses presence and extent of coronary calcification with lower radiation exposure","authors":"Alexa E. Golbus , John L. Schuzer , Shirley F. Rollison , Kathie C. Bronson , Scott P. Baute , Marcus Y. Chen","doi":"10.1016/j.jcct.2024.07.012","DOIUrl":"10.1016/j.jcct.2024.07.012","url":null,"abstract":"<div><h3>Background</h3><div>Cardiac CT for coronary artery calcium (CAC) scoring exposes patients to 1 mSv of radiation. A new CT scout method utilizing ultra-low dose CT (3D Landmark) offers tomographic cross-sectional imaging, which provides axial images from which CAC can be estimated. The purpose of our study is to analyze the association between estimated CAC burden on 3D Landmark scout imaging vs dedicated ECG-gated CACS.</div></div><div><h3>Methods</h3><div>Consecutive patients over a 9-month period undergoing non-contrast ECG-gated CACS planned with 3D Landmark scout imaging were included. Extent of CAC on 3D Landmark scout imaging was scored from 0 to 3 (none, mild, moderate, severe). Agatston CACS was converted to an ordinal score from 0 to 3, corresponding to absent (0), mild (1–99), moderate (100–400), or severe (>400). Fischer's exact test, weighted kappa coefficient, and paired t-tests were used for analysis.</div></div><div><h3>Results</h3><div>Of 150 patients, 51.3% were female with mean age 49.0 ± 16.8 and BMI 28.6 ± 12.3. Sensitivity of 3D Landmark in identifying calcium was 96.2%, with specificity of 100%. There was strong interrater agreement between 3D Landmark calcium scoring and CACS, with weighted kappa coefficient 0.97 ± 0.01(CI 0.95–0.99).</div><div>Radiation dose-length-product was significantly lower for 3D Landmark imaging vs. dedicated ECG-gated CACS (9.7 ± 3.6 vs 43.8 ± 26.4 mGy cm, p < 0.001) despite longer scan length (465.0 ± 160.8 vs 123.0 ± 12.7 mm, respectively).</div></div><div><h3>Conclusion</h3><div>Estimated coronary artery calcium on 3D Landmark scout images correlates strongly with Agatston CACS, demonstrating utility in assessing cardiovascular risk without introducing additional radiation or costs.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 593-596"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Baggiano , Francesca Baessato , Saima Mushtaq , Andrea Daniele Annoni , Francesco Cannata , Maria Ludovica Carerj , Alberico Del Torto , Fabio Fazzari , Alberto Formenti , Antonio Frappampina , Laura Fusini , Daniele Junod , Maria Elisabetta Mancini , Valentina Mantegazza , Riccardo Maragna , Francesca Marchetti , Francesco Paolo Sbordone , Luigi Tassetti , Alessandra Volpe , Marco Guglielmo , Gianluca Pontone
{"title":"STress computed tomogRaphy perfusion and stress cArdiac magnetic resonance for ThE manaGement of suspected or known coronarY artery disease: resources and outcomes impact","authors":"Andrea Baggiano , Francesca Baessato , Saima Mushtaq , Andrea Daniele Annoni , Francesco Cannata , Maria Ludovica Carerj , Alberico Del Torto , Fabio Fazzari , Alberto Formenti , Antonio Frappampina , Laura Fusini , Daniele Junod , Maria Elisabetta Mancini , Valentina Mantegazza , Riccardo Maragna , Francesca Marchetti , Francesco Paolo Sbordone , Luigi Tassetti , Alessandra Volpe , Marco Guglielmo , Gianluca Pontone","doi":"10.1016/j.jcct.2024.08.001","DOIUrl":"10.1016/j.jcct.2024.08.001","url":null,"abstract":"<div><h3>Background</h3><div>The aim of this study is to describe resources and outcomes of coronary computed tomography angiography plus Stress CT perfusion (CCTA + Stress-CTP) and stress cardiovascular magnetic resonance (Stress-CMR) in symptomatic patients with suspected or known CAD.</div></div><div><h3>Methods</h3><div>Six hundred and twenty-four consecutive symptomatic patients with intermediate to high-risk pretest likelihood for CAD or previous history of revascularization referred to our hospital for clinically indicated CCTA + Stress-CTP or Stress-CMR were enrolled. Stress-CTP scans were performed in 223 patients while 401 patients performed Stress-CMR. Patient follow-up was performed at 1 year after index test performance. Endpoints were all cardiac events, as a combined endpoint of revascularization, non-fatal MI and death, and hard cardiac events, as combined endpoint of non-fatal MI and death.</div></div><div><h3>Results</h3><div>Twenty-nine percent of patients who underwent CCTA + Stress-CTP received revascularization, 7% of subjects assessed with Stress-CMR were treated invasively, and a low number of non-fatal MI and death was observed with both strategies (hard events in 0.4% of patients that had CCTA + Stress-CTP as index test, and in 3% of patients evaluated with Stress-CMR). According to the predefined endpoints, CCTA + Stress-CTP group showed high rate of all cardiac events and low rate of hard cardiac events, respectively. The cumulative costs were 1970 ± 2506 Euro and 733 ± 1418 Euro for the CCTA + Stress-CTP group and Stress-CMR group, respectively.</div></div><div><h3>Conclusions</h3><div>The use of CCTA + Stress-CTP strategy was associated with high referral to revascularization but with a favourable trend in terms of hard cardiac events and diagnostic yield in identifying individuals at lower risk of adverse events despite the presence of CAD.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 553-558"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma L.R. Møller , Maria G. Hauge , Michael H.C. Pham , Peter Damm , Klaus F. Kofoed , Andreas Fuchs , Jørgen T. Kühl , Per E. Sigvardsen , Anne S. Ersbøll , Marianne Johansen , Børge G. Nordestgaard , Lars V. Køber , Finn Gustafsson , Jesper J. Linde
{"title":"Aortic dimensions in women with previous pre-eclampsia","authors":"Emma L.R. Møller , Maria G. Hauge , Michael H.C. Pham , Peter Damm , Klaus F. Kofoed , Andreas Fuchs , Jørgen T. Kühl , Per E. Sigvardsen , Anne S. Ersbøll , Marianne Johansen , Børge G. Nordestgaard , Lars V. Køber , Finn Gustafsson , Jesper J. Linde","doi":"10.1016/j.jcct.2024.06.001","DOIUrl":"10.1016/j.jcct.2024.06.001","url":null,"abstract":"<div><h3>Background</h3><div>Pre-eclampsia is a pregnancy related disorder associated with hypertension and vascular inflammation, factors that are also involved in the pathological pathway of aortic dilatation and aneurysm development. It is, however, unknown if younger women with previous pre-eclampsia have increased aortic dimensions. We tested the hypothesis that previous pre-eclampsia is associated with increased aortic dimensions in younger women.</div></div><div><h3>Methods</h3><div>The study was a cross-sectional cohort study of women with previous pre-eclampsia, aged 40–55, from the PRECIOUS population matched by age and parity with women from the general population. Using contrast-enhanced CT, aortic diameters were measured in the aortic root, ascending aorta, descending aorta, at the level of the diaphragm, suprarenal aorta, and infrarenal aorta.</div></div><div><h3>Results</h3><div>1355 women (684 with previous pre-eclampsia and 671 from the general population), with a mean (standard deviation) age of 46.9 (4.4) were included. The pre-eclampsia group had larger mean (standard deviation) aortic diameters (mm) in all measured segments from the ascending to the infrarenal aorta (ascending: 33.4 (4.0) vs. 31.4 (3.7), descending: 23.9 (2.1) vs. 23.3 (2.0), diaphragm: 20.8 (1.8) vs. 20.4 (1.8), suprarenal: 22.9 (1.9) vs. 22.0 (2.0), infrarenal: 19.3 (1.6) vs. 18.6 (1.7), p < 0.001 for all, also after adjustment for age, height, parity, menopause, dyslipidemia, smoking and chronic hypertension. Guideline-defined ascending aortic aneurysms were found in 8 vs 2 women (p = 0.12).</div></div><div><h3>Conclusions</h3><div>Women with previous pre-eclampsia have larger aortic dimensions compared with women from the general population. Pre-eclampsia was found to be an independent risk factor associated with a larger aortic diameter.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 533-540"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelle C. Williams , Jonathan R. Weir-McCall , Lauren A. Baldassarre , Carlo N. De Cecco , Andrew D. Choi , Damini Dey , Marc R. Dweck , Ivana Isgum , Márton Kolossvary , Jonathon Leipsic , Andrew Lin , Michael T. Lu , Manish Motwani , Koen Nieman , Leslee Shaw , Marly van Assen , Edward Nicol
{"title":"Artificial Intelligence and Machine Learning for Cardiovascular Computed Tomography (CCT): A White Paper of the Society of Cardiovascular Computed Tomography (SCCT)","authors":"Michelle C. Williams , Jonathan R. Weir-McCall , Lauren A. Baldassarre , Carlo N. De Cecco , Andrew D. Choi , Damini Dey , Marc R. Dweck , Ivana Isgum , Márton Kolossvary , Jonathon Leipsic , Andrew Lin , Michael T. Lu , Manish Motwani , Koen Nieman , Leslee Shaw , Marly van Assen , Edward Nicol","doi":"10.1016/j.jcct.2024.08.003","DOIUrl":"10.1016/j.jcct.2024.08.003","url":null,"abstract":"","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 519-532"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daisuke Kinoshita , Keishi Suzuki , Daichi Fujimoto , Takayuki Niida , Eisuke Usui , Yoshiyasu Minami , Damini Dey , Hang Lee , Iris McNulty , Junya Ako , Maros Ferencik , Tsunekazu Kakuta , Ik-Kyung Jang
{"title":"Relationship between plaque burden and plaque vulnerability: Acute coronary syndromes versus chronic coronary syndrome","authors":"Daisuke Kinoshita , Keishi Suzuki , Daichi Fujimoto , Takayuki Niida , Eisuke Usui , Yoshiyasu Minami , Damini Dey , Hang Lee , Iris McNulty , Junya Ako , Maros Ferencik , Tsunekazu Kakuta , Ik-Kyung Jang","doi":"10.1016/j.jcct.2024.09.002","DOIUrl":"10.1016/j.jcct.2024.09.002","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between plaque burden and microscopic characterization of plaque features as it pertains to clinical presentation has not been fully investigated. The aim of this study was to compare the relationship between plaque burden and plaque vulnerability in patients with acute coronary syndromes (ACS) versus chronic coronary syndrome (CCS).</div></div><div><h3>Methods</h3><div>Patients who underwent both coronary computed tomography angiography (CTA) and optical coherence tomography (OCT) before coronary intervention were enrolled. All plaques were detected in culprit vessels using CTA, and total plaque volume (TPV) and OCT features were assessed at the corresponding sites. All plaques were divided into three groups according to the tertile levels of TPV (low TPV: <96.5 mm<sup>3</sup>, moderate TPV: 96.5–164.7 mm<sup>3</sup>, high TPV: ≥164.8 mm<sup>3</sup>).</div></div><div><h3>Results</h3><div>A total of 990 plaques were imaged by OCT in 419 patients: 445 plaques in 190 (45.3%) patients with ACS and 545 in 229 (54.7%) with CCS. Macrophage was more prevalent in plaques with greater TPV in patients who presented with ACS but not in those who presented with CCS (low vs. moderate vs. high TPV group: macrophage 57.4% vs. 71.8% vs. 82.4% in ACS; 63.4% vs. 67.8% vs. 66.7% in CCS; interaction <em>P</em> = 0.004). Lipid arc increased as TPV increased, especially in patients who presented with ACS. Conversely, the layer index increased as TPV increased in patients with CCS.</div></div><div><h3>Conclusion</h3><div>Greater plaque burden was closely related to higher levels of plaque vulnerability in ACS and greater volume of layered plaque in CCS.</div></div><div><h3>Trial registration</h3><div><span><span>clinicaltrials.gov</span><svg><path></path></svg></span> Identifier: NCT04523194.</div></div>","PeriodicalId":49039,"journal":{"name":"Journal of Cardiovascular Computed Tomography","volume":"18 6","pages":"Pages 559-566"},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142304925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}