Amelia Pasqual Marques, Adriana de Sousa do Espírito Santo, Ana Assumpção Berssaneti, Luciana Akemi Matsutani, Susan Lee King Yuan
{"title":"A prevalência de fibromialgia: atualização da revisão de literatura","authors":"Amelia Pasqual Marques, Adriana de Sousa do Espírito Santo, Ana Assumpção Berssaneti, Luciana Akemi Matsutani, Susan Lee King Yuan","doi":"10.1016/j.rbr.2016.10.004","DOIUrl":"https://doi.org/10.1016/j.rbr.2016.10.004","url":null,"abstract":"<div><p>The present study aimed to update the literature review on the prevalence of fibromyalgia (FM) published in 2006. A bibliographical survey was carried out from 2005 to 2014 in the MEDLINE, Web of Science, Embase, LILACS and SciELO databases and 3274 records were identified. Five researchers selected the studies, following the inclusion criteria: studies that obtained the prevalence of FM. FM studies in associated diseases were excluded. When screening by title and abstract, 2073 irrelevant articles were excluded. The full texts of 210 articles were evaluated for eligibility and this review included 39 studies, described in 41 articles. The selected studies were grouped into four categories: a) prevalence of FM in the general population; B) prevalence of FM in women; <span>C</span>) prevalence of FM in rural and urban areas; D) prevalence of FM in special populations. The literature shows values of FM prevalence in the general population between 0.2 and 6.6%, in women between 2.4 and 6.8%, in urban areas between 0.7 and 11.4%, in rural areas between 0.1 and 5.2%, and in special populations values between 0.6 and 15%. This literature review update shows a significant increase in FM prevalence studies in the world. The new 2010 American College of Rheumatology criteria have not been widely used yet and the COPCORD (Community‐oriented program for control of Rheumatic Diseases) methodology has increased the quality of studies on the prevalence of rheumatic diseases in general.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.10.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72245029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Bertoldi Fonseca, Francisco Edvan Rodrigues Gomes, E. T. Valera, G. Pileggi, Paula Braga Gonfiantini, Marcela Braga Gonfiantini, V. Ferriani, L. M. Carvalho
{"title":"Signs and symptoms of rheumatic diseases as first manifestation of pediatric cancer: diagnosis and prognosis implications.","authors":"Mariana Bertoldi Fonseca, Francisco Edvan Rodrigues Gomes, E. T. Valera, G. Pileggi, Paula Braga Gonfiantini, Marcela Braga Gonfiantini, V. Ferriani, L. M. Carvalho","doi":"10.1016/j.rbr.2016.11.001","DOIUrl":"https://doi.org/10.1016/j.rbr.2016.11.001","url":null,"abstract":"","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.11.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48894088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Fernanda B. Resende Guimarães , Maria Raquel da Costa Pinto , Renata G. Santos Couto Raid , Marcus Vinícius Melo de Andrade , Adriana Maria Kakehasi
{"title":"Qual o melhor ponto de corte de índice de massa corporal para diagnosticar a obesidade em mulheres com artrite reumatoide? Um estudo que usa a composição corporal pela absorciometria com raios X de dupla energia","authors":"Maria Fernanda B. Resende Guimarães , Maria Raquel da Costa Pinto , Renata G. Santos Couto Raid , Marcus Vinícius Melo de Andrade , Adriana Maria Kakehasi","doi":"10.1016/j.rbr.2015.09.008","DOIUrl":"10.1016/j.rbr.2015.09.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Standard anthropometric measures used to diagnose obesity in the general population may not have the same performance in patients with rheumatoid arthritis.</p></div><div><h3>Objective</h3><p>To determine cutoff points for body mass index (BMI) and waist circumference (WC) for detecting obesity in women with rheumatoid arthritis (RA) by comparing these standard anthropometric measures to a dual‐energy x‐ray absorptiometry (DXA)‐based obesity criterion.</p></div><div><h3>Patients and method</h3><p>Adult female patients with more than six months of diagnosis of RA underwent clinical evaluation, with anthropometric measures and body composition with DXA.</p></div><div><h3>Results</h3><p>Eighty two patients were included, mean age 55<!--> <!-->±<!--> <!-->10.7 years. The diagnosis of obesity in the sample was about 31.7% by BMI, 86.6% by WC and 59.8% by DXA. Considering DXA as golden standard, Cutoff points were identified for anthropometric measures to better approximate DXA estimates of percent body fat: for BMI value ≥ 25<!--> <!-->kg/m<sup>2</sup> was the best for definition of obesity in female patients with RA, with sensitivity of 80% and specificity of 60%. For WC, with 80% of sensitivity and 35% of specificity, the best value to detect obesity was 86<!--> <!-->cm.</p></div><div><h3>Conclusion</h3><p>A large percentage of patients were obese. The traditional cutoff points used for obesity were not suitable for our sample. For this female population with established RA, BMI cutoff point of 25<!--> <!-->kg/m<sup>2</sup> and WC cutoff point of 86<!--> <!-->cm were the most appropriate to detect obesity.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2015.09.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46653539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Independência de isoformas de transferrina deficiente em carboidrato e peptídeos citrulinados cíclicos na artrite reumatoide","authors":"Monika Gudowska , Ewa Gindzienska‐Sieskiewicz , Ewa Gruszewska , Bogdan Cylwik , Stanislaw Sierakowski , Maciej Szmitkowski , Lech Chrostek","doi":"10.1016/j.rbr.2016.01.001","DOIUrl":"10.1016/j.rbr.2016.01.001","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this study was to assess the relationship between the two types of posttranslational modifications of proteins in RA: glycosylation on the example of carbohydrate‐deficient transferrin (CDT) and citrullination by means of autoantibodies to cyclic citrullinated peptides (anti‐CCP).</p></div><div><h3>Methods</h3><p>The study was carried out in 50 RA patients. CDT was measured using N Latex CDT immunonephelometric test, the results were presented in absolute and relative units. Anti‐CCP were measured using the chemiluminescent method and rheumatoid factor (RF) by immunoturbidimetric method.</p></div><div><h3>Results</h3><p>80% of RA patients were positive for anti‐CCP, 70% for RF and 62% for both, anti‐CCP and RF. The level of %CDT was significantly elevated, but absolute CDT level was not changed. The mean absolute CDT concentration was higher in anti‐CCP positive patients than that in anti‐CCP negative. CDT (absolute and relative concentration) did not correlate with anti‐CCP and RF. However, serum RF significantly correlated with anti‐CCP. %CDT did not correlate with anti‐CCP, but absolute level correlated with anti‐CCP only in anti‐CCP negative and RF negative patients. CDT did not correlate with RF, but solely with anti‐CCP in anti‐CCP negative patients. Anti‐CCP correlated with DAS 28 only in anti‐CCP negative RA, but CDT (absolute and relative units) correlated with DAS 28 in all patients and in anti‐CCP positive RA.</p></div><div><h3>Conclusions</h3><p>These results suggest that the changes in CDT and anti‐CCP concentrations are not associated with oneself and indicate on the independence of these posttranslational modifications in rheumatoid arthritis. Only the alterations in transferrin glycosylation reflected the activity of RA.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55035280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rafael Kmiliauskis Santos Gomes , Fabio Antero Pires , Moacyr Roberto Cuce Nobre , Mauricio Felippi de Sá Marchi , Jennifer Cristina Kozechen Rickli
{"title":"Impacto da artrite reumatoide no sistema público de saúde em Santa Catarina, Brasil: análise descritiva e de tendência temporal de 1996 a 2009","authors":"Rafael Kmiliauskis Santos Gomes , Fabio Antero Pires , Moacyr Roberto Cuce Nobre , Mauricio Felippi de Sá Marchi , Jennifer Cristina Kozechen Rickli","doi":"10.1016/j.rbr.2016.05.003","DOIUrl":"10.1016/j.rbr.2016.05.003","url":null,"abstract":"<div><h3>Introduction</h3><p>There are few studies that carried out a descriptive and trend analysis based on available data from the Unified Health System (SUS) between pre‐ and post‐free dispensing of pharmacological treatment of rheumatoid arthritis (RA) from the perspective of the public health system, in terms of the direct cost of the disease among adults and elderly residents of the state of Santa Catarina, Brazil. This study aims to characterize the direct cost of medical and surgical procedures before and after the dispensing of drugs in this state.</p></div><div><h3>Methods</h3><p>This is a time series‐type study with a cross‐sectional survey of data from the Hospital (SIH) and Outpatient (SIA) Information System of SUS during the period from 1996 to 2009.</p></div><div><h3>Results</h3><p>Between 1996 and 2009, the total expenditure for hospital‐ and outpatient pharmacological treatment of rheumatoid arthritis was R$ 26,659,127.20. After the dispensing of drug treatment by SUS a decrease of 36% in the number of hospital admissions was observed; however, an increase of 19% in clinical procedures was noted.</p></div><div><h3>Conclusion</h3><p>During the observed period, a reduction in the number of hospital admissions for both clinical and orthopedic surgical procedures related to this disease was observed. Nevertheless, there was an increase in the cost of medical admissions.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.05.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45917429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
João Paulo M. Santos , Rubens A. da Silva , Marcos Tadeu P. Fernandes , Regina Célia Poli‐Frederico , Denis C. Santos , Rodrigo A.C. Andraus , Thais Maria F. Fernandes , Karen B.P. Fernandes
{"title":"Uso do questionário Lower Extremity Functional Scale (LEFS‐Brasil) em comparação com o Índice Algofuncional de Lequesne para definição de gravidade na osteoartrite de joelho e quadril","authors":"João Paulo M. Santos , Rubens A. da Silva , Marcos Tadeu P. Fernandes , Regina Célia Poli‐Frederico , Denis C. Santos , Rodrigo A.C. Andraus , Thais Maria F. Fernandes , Karen B.P. Fernandes","doi":"10.1016/j.rbr.2016.04.005","DOIUrl":"10.1016/j.rbr.2016.04.005","url":null,"abstract":"","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.04.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42143966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana de Almeida Lourenço , Izabela Roma , Marcos Renato de Assis
{"title":"Ocorrência de quedas e sua associação com testes físicos, capacidade funcional e aspectos clínicos e demográficos em pacientes com artrite reumatoide","authors":"Mariana de Almeida Lourenço , Izabela Roma , Marcos Renato de Assis","doi":"10.1016/j.rbr.2016.08.003","DOIUrl":"10.1016/j.rbr.2016.08.003","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the occurrence of falls reported by rheumatoid arthritis patients and its relation to disease activity, functional capacity and physical fitness.</p></div><div><h3>Material and methods</h3><p>A cross-sectional study constituted by a sample of 97 rheumatoid arthritis patients from the city of Marília (SP) from 2012 to 2013, were assessed for disease activity. Instruments validated for Brazilian population in order to evaluate physical and functional capacity were used. Data analysis was carried out with descriptive statistics, Spearman correlation and Chi-squared test, considering <em>p</em> <!--><<!--> <!-->0.05.</p></div><div><h3>Results</h3><p>88.7% were female subjects with a mean age of 56 (±11.7) years. The median duration of rheumatoid arthritis was 10 years (P25<!--> <!-->=<!--> <!-->6 and P75<!--> <!-->=<!--> <!-->17) and the mean of disease activity was 3.6 (±1.3), what was considered a moderate activity. In the last 12 months 37.1% of patients experienced at least one fall, with a total of 52 episodes, and fear of falling was reported by 74.2% of them, but this was not associated to the occurrence of a fall (<em>χ</em><sup>2</sup> <!-->=<!--> <!-->1.19, <em>p</em> <!-->=<!--> <!-->0.27). Gender, number of medications, age, disease activity, duration of rheumatoid arthritis, functional capacity, and physical tests showed no associations with history of falls in the past year.</p></div><div><h3>Conclusion</h3><p>It was observed that the occurrence of falls and the fear of falling are quite common in this population. The occurrence of falls in this sample of rheumatoid arthritis patients bears no relation to disease activity, functional capacity, or physical fitness tests.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.08.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41929180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammet Cinar , Sedat Yilmaz , Sinan Akay , Ugur Bozlar , Ayhan Dinc
{"title":"Evolução clínica da doença de Behçet em paciente com atraso do diagnóstico e seguimento radiológico dos trombos com angiotomografia computadorizada: seguimento por 5 anos durante tratamento imunossupressor","authors":"Muhammet Cinar , Sedat Yilmaz , Sinan Akay , Ugur Bozlar , Ayhan Dinc","doi":"10.1016/j.rbr.2013.08.004","DOIUrl":"10.1016/j.rbr.2013.08.004","url":null,"abstract":"","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2013.08.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42727171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro A. Laires , Jorge Laíns , Luís C. Miranda , Rui Cernadas , Srini Rajagopalan , Stephanie D. Taylor , José C. Silva
{"title":"Alívio inadequado da dor em pacientes com osteoartrite de joelho primária","authors":"Pedro A. Laires , Jorge Laíns , Luís C. Miranda , Rui Cernadas , Srini Rajagopalan , Stephanie D. Taylor , José C. Silva","doi":"10.1016/j.rbr.2016.09.003","DOIUrl":"10.1016/j.rbr.2016.09.003","url":null,"abstract":"<div><h3>Background</h3><p>Despite the widespread treatments for osteoarthritis (OA), data on treatment patterns, adequacy of pain relief, and quality of life are limited. The prospective multinational Survey of Osteoarthritis Real World Therapies (SORT) was designed to investigate these aspects.</p></div><div><h3>Objectives</h3><p>To analyze the characteristics and the patient reported outcomes of the Portuguese dataset of SORT at the start of observation.</p></div><div><h3>Methods</h3><p>Patients ≥50 years with primary knee OA who were receiving oral or topical analgesics were eligible. Patients were enrolled from seven healthcare centers in Portugal between January and December 2011. Pain and function were evaluated using the Brief Pain Inventory (BPI) and WOMAC. Quality of life was assessed using the 12-Item Short Form Health Survey (SF-12). Inadequate pain relief (IPR) was defined as a score >4/10 on item 5 of the BPI.</p></div><div><h3>Results</h3><p>Overall, 197 patients were analyzed. The median age was 67.0 years and 78.2% were female. Mean duration of knee OA was 6.2 years. IPR was reported by 51.3% of patients. Female gender (adjusted odds ratio – OR 2.15 [95%CI 1.1, 4.5]), diabetes (OR 3.1 [95%CI 1.3, 7.7]) and depression (OR 2.24 [95%CI 1.2, 4.3]) were associated with higher risk of IPR. Patients with IPR reported worst outcomes in all dimensions of WOMAC (<em>p</em> <!--><<!--> <!-->0.001) and in all eight domains and summary components of SF-12 (<em>p</em> <!--><<!--> <!-->0.001).</p></div><div><h3>Conclusions</h3><p>Our findings indicate that improvements are needed in the management of pain in knee OA in order to achieve better outcomes in terms of pain relief, function and quality of life.</p></div>","PeriodicalId":48991,"journal":{"name":"Revista Brasileira De Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rbr.2016.09.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42552557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}