Revista Portuguesa De Cardiologia最新文献

{"title":"Cryoablation for perinodal supraventricular tachycardia: Safety first in a high-risk neighborhood","authors":"Ana Margarida Lebreiro","doi":"10.1016/j.repc.2026.05.002","DOIUrl":"10.1016/j.repc.2026.05.002","url":null,"abstract":"","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 279-280"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147943418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When the valve bites back: Circumflex occlusion after mitral valve surgery","authors":"Inês Ferreira Neves, Pedro Garcia Brás, Tiago Pereira da Silva","doi":"10.1016/j.repc.2026.02.005","DOIUrl":"10.1016/j.repc.2026.02.005","url":null,"abstract":"","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 319-321"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocarditis in athletes: Challenges for return to play","authors":"Hélder Dores ,&nbsp;Paulo Dinis ,&nbsp;Luís Puga ,&nbsp;António Freitas ,&nbsp;Nuno Cardim","doi":"10.1016/j.repc.2026.02.006","DOIUrl":"10.1016/j.repc.2026.02.006","url":null,"abstract":"<div><div>Myocarditis is a condition characterized by heterogeneous etiologies, clinical manifestations, and natural history. Its diagnosis remains challenging and requires a multidisciplinary approach that integrates clinical evaluation, biomarkers, electrocardiography, echocardiography, and advanced imaging modalities. Cardiac magnetic resonance has emerged as the non-invasive gold-standard test that together with endomyocardial biopsy, constitutes the foundation of the current diagnostic classification. Myocarditis is also a frequent acquired cause of sudden cardiac death in young individuals, including athletes. In this setting, the evaluation of return-to-play eligibility in athletes after acute myocarditis is complex and often limited by scarce evidence-based data. Accurate risk stratification, guided by a comprehensive multiparametric evaluation and a shared decision-making process that considers the potential risks of resuming competitive sport, is fundamental to ensuring athlete safety. This review aims to discuss the management of athletes with myocarditis and to address the challenges associated with return-to-play decisions.</div></div>","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 307-317"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive pulmonary embolism: Multimodal diagnostic approach and percutaneous mechanical thrombectomy","authors":"Raymundo Ocaranza-Sanchez ,&nbsp;Aldo Gabriel Negrette-Merino ,&nbsp;Blanca Estela Fernández-Candelario ,&nbsp;Juan Carlos Betancourt-Villarruel ,&nbsp;Jesus Rodrigo Canto-García ,&nbsp;Juan Carlos Pérez-Alva","doi":"10.1016/j.repc.2026.01.009","DOIUrl":"10.1016/j.repc.2026.01.009","url":null,"abstract":"","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 327-328"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic role of lactoferrin against doxorubicin-induced cardiotoxicity in Wistar rats","authors":"Vinay Kumar ,&nbsp;Virendra Pratap Singh Rathor ,&nbsp;Paritosh Kunwar Singh ,&nbsp;Mohamad Taleuzzaman","doi":"10.1016/j.repc.2025.11.013","DOIUrl":"10.1016/j.repc.2025.11.013","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Doxorubicin-associated cardiotoxicity is an alarming concern as it limits the use of anticancer drugs in a clinical setting. The objective of this study was to test the therapeutic role of lactoferrin in preventing doxorubicin-induced cardiotoxicity and thus address this severe side effect of chemotherapy.</div></div><div><h3>Methods</h3><div>Wistar rats received vehicle or DOX (2.5 mg/kg, i.p.) three times a week for two weeks and lactoferrin (50 mg/kg, i.p.) for 15 days (i.e., from day 1 to day 15 along with DOX). Changes in body weight, heart weight, and cardiotoxicity markers (blood pressure, LDH, CK-MB, and cardiac troponin I) were evaluated. Furthermore, all the animals were evaluated for the modulation of inflammatory markers (BNP, IL-6, CRP, and TNF-α), histopathological changes in heart tissue, and oxidant and antioxidant status.</div></div><div><h3>Results</h3><div>Doxorubicin significantly (p&lt;0.01) reduced body weight and increased the levels of cardiotoxic biomarkers (blood pressure, LDH, CK-MB, BNP, cardiac troponin I, IL-6, CRP, and TNF-α), whereas these effects were reversed in lactoferrin-treated animals. Histopathologically, heart tissue in the doxorubicin-treated group was found to contain muddled myocardial fibers, dilated blood capillaries, and necrosis in muscle fibers; however, these abnormalities were restored to normal levels in the lactoferrin therapy group. Finally, lactoferrin significantly (p&lt;0.05) increased the levels of antioxidative enzymes (glutathione and SOD) and decreased the levels of oxidants (NO) compared with those in the untreated cardiotoxicity group.</div></div><div><h3>Conclusion</h3><div>The present study revealed the immunomodulatory, antioxidative potential of lactoferrin in restoring normal heart tissue, thereby mitigating the effects of doxorubicin-induced cardiotoxicity.</div></div>","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 295-303"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to build the best bridge(s) to heart transplantation: Deciphering the interplay between patient and devices","authors":"António Tralhão","doi":"10.1016/j.repc.2026.05.001","DOIUrl":"10.1016/j.repc.2026.05.001","url":null,"abstract":"","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 291-293"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147943359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the Letter to the Editor “Sex imbalance in a large Fontan cohort: Biological reality or marker of inequitable care?”","authors":"Tianyu Chen,&nbsp;Jian Zhuang","doi":"10.1016/j.repc.2026.02.002","DOIUrl":"10.1016/j.repc.2026.02.002","url":null,"abstract":"","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 333-334"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147328140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First phase implementation of the REACT program in Portugal: Resuscitation and emergencies in the interventional cardiology unit","authors":"João Mirinha Luz ,&nbsp;Ana Rita Pereira ,&nbsp;Nuno Baltazar ,&nbsp;Nuno Oliveira ,&nbsp;Hélder Pereira","doi":"10.1016/j.repc.2026.02.004","DOIUrl":"10.1016/j.repc.2026.02.004","url":null,"abstract":"","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 323-325"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive factors of mortality with short-term ventricular assist devices for heart transplantation","authors":"Carlos Domínguez-Massa ,&nbsp;Eduardo Tébar-Botí ,&nbsp;Manuel Pérez-Guillén ,&nbsp;Iratxe Zarragoikoetxea-Jauregui ,&nbsp;María José Dalmau-Sorlí ,&nbsp;Salvador Torregrosa-Puerta ,&nbsp;Francisco José Valera-Martínez ,&nbsp;Iván Martín-González ,&nbsp;Ana María Bel-Mínguez ,&nbsp;Raquel López-Vilella ,&nbsp;Ricardo Gimeno-Costa ,&nbsp;Juan Bautista Martínez-León","doi":"10.1016/j.repc.2025.12.013","DOIUrl":"10.1016/j.repc.2025.12.013","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The shortage of donor hearts has led to an increased use of temporary mechanical circulatory support as a bridge to urgent heart transplantation (HT). This study aimed to identify predictors of in-hospital mortality in patients supported with short-term ventricular assist devices (VADs), specifically CentriMag and Impella, as a bridge to HT, used either as direct implantation or following prior extracorporeal membrane oxygenation support (ECMO).</div></div><div><h3>Methods</h3><div>Retrospective, single-center, observational study conducted at a tertiary care center, including all patients receiving short-term VADs, specifically CentriMag and Impella, as a bridge to HT between 2016 and 2024.</div></div><div><h3>Results</h3><div>A total of 73 patients were included: 22 received VAD following prior ECMO support (27.3% underwent transplantation; 50% in-hospital mortality post-transplant), and 51 underwent direct VAD implantation (80.4% underwent transplantation; 9.8% in-hospital mortality post-transplant). Independent predictors of in-hospital mortality included: use of CentriMag as left-sided VAD, acute coronary syndrome (ACS), VAD implantation following prior ECMO support, infection, and female sex. After adjustment for confounding variables, prior ECMO support before VAD implantation remained significantly associated with increased in-hospital mortality.</div></div><div><h3>Conclusions</h3><div>The complex nature of patients requiring short-term VADs and the physiological impact of different devices must be addressed early and individually, based on the etiology of the shock and urgency status. In-hospital mortality was significantly higher among patients previously supported with ECMO, which highlights the importance of timely and optimized management to mitigate complications and enhance outcomes.</div></div>","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 6","pages":"Pages 281-289"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver embolization of a pacemaker lead fragment: A rare extraction complication","authors":"Inês Ferreira Neves,&nbsp;Bruno Valente,&nbsp;Hélder Santos,&nbsp;Mário Martins Oliveira","doi":"10.1016/j.repc.2026.02.003","DOIUrl":"10.1016/j.repc.2026.02.003","url":null,"abstract":"","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":"45 5","pages":"Pages 259-260"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}