Revista Portuguesa De Cardiologia最新文献

Variability of the antithrombotic effect of acetylsalicylic acid with the administration of different dosages: reality or myth? 不同剂量乙酰水杨酸抗血栓作用的变异性：现实还是神话？

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-27 DOI: 10.1016/j.repc.2025.01.005

Joana Lima Lopes, Mariana Dias Passos, Carolina Pereira Mateus, Inês Sofia Fialho, Vanessa de Oliveira, Diana Sousa Mendes, João Bicho Augusto, David Cabrita Roque

{"title":"Variability of the antithrombotic effect of acetylsalicylic acid with the administration of different dosages: reality or myth?","authors":"Joana Lima Lopes, Mariana Dias Passos, Carolina Pereira Mateus, Inês Sofia Fialho, Vanessa de Oliveira, Diana Sousa Mendes, João Bicho Augusto, David Cabrita Roque","doi":"10.1016/j.repc.2025.01.005","DOIUrl":"https://doi.org/10.1016/j.repc.2025.01.005","url":null,"abstract":"Introduction and objectives: Acetylsalicylic acid (ASA) has both antithrombotic and anti-inflammatory effects, the latter being achieved when administered at higher doses (500 mg, 1000 mg per os). However, it is not known whether the anti-inflammatory effect decreases the antithrombotic potency of ASA. This experimental study intends to assess whether ASA maintains its antithrombotic effect when administered in an anti-inflammatory dose.Methods: Twenty healthy volunteers were recruited and randomized into four groups. Each group ingested ASA 100 mg, 300 mg, 500 mg, and 1000 mg respectively. Their basal platelet function was measured using PFA-200 technology and reassessed one hour after ASA ingestion.Results: The volunteers were all antiaggregated after ingestion of ASA, regardless of the dose taken. No statistical significance was found regarding age or gender. A subanalysis was performed, comparing the two groups that ingested lower dosages (100 mg and 300 mg) against the group that ingested higher dosages (500 mg and 1000 mg). The results were statistically significant, suggesting higher dosages may correspond to a higher antithrombotic effect.Conclusions: Acetylsalicylic acid maintains its antithrombotic effect when administered in an anti-inflammatory dose. There is no clear association between the potency of antithrombotic effect and the ASA dose administered; however, our subanalysis suggests that higher dosages may correspond to a higher potency of antiaggregation.","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-year recurrence rate of new-onset atrial fibrillation after acute myocardial infarction. 急性心肌梗死后新发房颤的1年复发率。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-19 DOI: 10.1016/j.repc.2024.12.008

Alicia Prieto-Lobato, Víctor Hidalgo Olivares, Manuel Gerónimo Pardo, Marta Cubells Pastor, Francisco Manuel Salmerón Martínez, Miguel José Corbí-Pascual

{"title":"One-year recurrence rate of new-onset atrial fibrillation after acute myocardial infarction.","authors":"Alicia Prieto-Lobato, Víctor Hidalgo Olivares, Manuel Gerónimo Pardo, Marta Cubells Pastor, Francisco Manuel Salmerón Martínez, Miguel José Corbí-Pascual","doi":"10.1016/j.repc.2024.12.008","DOIUrl":"https://doi.org/10.1016/j.repc.2024.12.008","url":null,"abstract":"Introduction and objectives: Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with a prevalence of up to 21% in the early phase of acute myocardial infarction (AMI). Data on new-onset AF in this context are limited, and long-term prognosis remains unclear.Methods: We conducted a retrospective observational cohort study from December 2011 to May 2021, including patients who experienced a first episode of paroxysmal AF during hospitalization for AMI. The primary outcome was the recurrence of AF within the first-year post discharge. Secondary outcomes included all-cause mortality, cardiovascular mortality, and a composite of major adverse cardiovascular events.Results: A total of 209 patients were included. There was AF recurrence in 19 patients, 9.1% (95% CI 5.2-13.0%) with a median time to recurrence of 84 days [interquartile range 27.5-157.5]. While mortality in the AF recurrence group was numerically higher than in the non-AF recurrence group, this difference did not achieve statistical significance (15.8% vs. 7.4%, p=0.19). Patients with AF recurrence had significantly worse prognosis (47.4% vs. 23.7%, p=0.04), primarily due to increased heart failure (HF) hospitalizations.Conclusions: In patients with a first episode of paroxysmal AF during AMI, one-year recurrence is relatively low (9.1%); however; AF recurrence is associated with significantly worse prognosis, driven largely by HF hospitalizations.","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First experience implanting a second leadless pacemaker. 第一次植入第二个无铅起搏器。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-13 DOI: 10.1016/j.repc.2024.11.019

Ana Rita Bello, Joana Certo Pereira, Pedro Galvão Santos, Diogo Cavaco, Pedro Adragão

引用次数: 0

Electronic health records-based research in Cardiology: The time has come for pragmatic trials. 心脏病学中基于电子健康记录的研究：进行实用试验的时候到了。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-07 DOI: 10.1016/j.repc.2024.12.007

Daniel Seabra, Afonso Oliveira, Cristina Gavina

引用次数: 0

Exercise prescription in cardiac rehabilitation for heart failure patients: Why threshold-based training matters. 心力衰竭患者心脏康复的运动处方：为什么阈值训练很重要。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-06 DOI: 10.1016/j.repc.2025.05.002

Anaí Durazzo

引用次数: 0

Recurrent dissection of left coronary artery with extension to the left main and cardiogenic shock. 复发性左冠状动脉解剖延伸至共干及致心性休克。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-06 DOI: 10.1016/j.repc.2025.02.006

Michele Galasso, Isidoro Pera, Martina Milani, Andrea Farina, Gianluca Tiberti, Silvia Massaro, Giuseppe Uccello

引用次数: 0

Establishing a left bundle branch area pacing program: Results from a high-volume pacing center. 建立左束分支区域起搏程序：高容量起搏中心的结果。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-06 DOI: 10.1016/j.repc.2024.12.006

João Ferreira, Diogo Fernandes, Patrícia Marques-Alves, Carolina Saleiro, Luís Elvas, Lino Gonçalves

{"title":"Establishing a left bundle branch area pacing program: Results from a high-volume pacing center.","authors":"João Ferreira, Diogo Fernandes, Patrícia Marques-Alves, Carolina Saleiro, Luís Elvas, Lino Gonçalves","doi":"10.1016/j.repc.2024.12.006","DOIUrl":"10.1016/j.repc.2024.12.006","url":null,"abstract":"Introduction and objectives: Left bundle branch area pacing (LBBAP) is a technique suitable for treating both symptomatic bradycardia and cardiac resynchronization therapy (CRT). Our study aims to describe the first experience of LBBAP in a high-volume cardiac implantable electronic device (CIED) center.Methods: This prospective single-center observational registry included consecutive patients who underwent pacemaker implantation with LBBAP technique for sinus node disease, bradycardia and CRT indications between January 2023 and January 2024. Procedural data, outcomes, and lead parameters were recorded at hospital discharge, at one and six months of follow-up.Results: A total of 164 consecutive patients undergoing LBBAP implantation were included, of whom 142 had a stylet-driven lead. LLBAP was achieved in 94.5% patients. Average QRS duration was 139.8±33.4 ms. Complete atrioventricular block was the most common indication (42.7%). CRT was performed in 24 (14.5%) patients. Mean procedural duration was 82.7±24.4 min and mean fluoroscopy time was 13.7±7.1 min. Average LVAT was 78.8±8.7 ms and paced QRS width 114.8±14.4 ms. Median acute R-wave amplitude was 14.0 mV, pacing threshold was 0.5 V and impedance 526 Ω. No relevant per-operative complications occurred. After one month of follow-up, median pacing threshold had significantly increased to 0.75 V (p<0.001) while R-wave amplitude and impedance remained unchanged (p=0.242 and p=0.101 respectively). During follow-up, no changes occurred in the evaluated parameters. Loss of left bundle branch capture occurred in five patients and macro-dislodgement in 2.Conclusion: LBBAP is a feasible pacing technique which reduces QRS duration and improves LV synchrony and can be adopted at most centers, with favorable success rates and safety profile.","PeriodicalId":48985,"journal":{"name":"Revista Portuguesa De Cardiologia","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multimorbidity approach in elderly patients with atrial fibrillation. The upcoming EHRA-PATHS project. 老年房颤多病治疗。即将到来的EHRA-PATHS项目。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-05-02 DOI: 10.1016/j.repc.2025.05.001

Mário Oliveira, Michiel Rienstra, Hein Heidbuchel, Isabelle Van Gelder

引用次数: 0

Expanding left bundle branch area pacing - A new step in daily practice. 扩大左束支区起搏——日常练习的新步骤。

IF 1.6 4区医学

Revista Portuguesa De Cardiologia Pub Date : 2025-04-30 DOI: 10.1016/j.repc.2025.04.004

Mário Oliveira

引用次数: 0

A large-scale biobank and more genome-wide association studies of cardiovascular disease are needed in Portugal. 葡萄牙需要大规模的生物库和更多的心血管疾病全基因组关联研究。