Genome Biology最新文献_第6页

seqQscorer: automated quality control of next-generation sequencing data using machine learning. seqQscorer:使用机器学习的下一代测序数据的自动质量控制。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-03-05 DOI: 10.1186/s13059-021-02294-2

Steffen Albrecht, Maximilian Sprang, Miguel A Andrade-Navarro, Jean-Fred Fontaine

引用次数: 8

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells. 单细胞eQTL分析确定了成纤维细胞和重编程诱导多能干细胞中基因表达的细胞类型特异性遗传控制。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-03-05 DOI: 10.1186/s13059-021-02293-3

Drew Neavin, Quan Nguyen, Maciej S Daniszewski, Helena H Liang, Han Sheng Chiu, Yong Kiat Wee, Anne Senabouth, Samuel W Lukowski, Duncan E Crombie, Grace E Lidgerwood, Damián Hernández, James C Vickers, Anthony L Cook, Nathan J Palpant, Alice Pébay, Alex W Hewitt, Joseph E Powell

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引用次数: 48

simATAC: a single-cell ATAC-seq simulation framework. simATAC:单细胞ATAC-seq仿真框架。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-03-04 DOI: 10.1186/s13059-021-02270-w

Zeinab Navidi, Lin Zhang, Bo Wang

引用次数: 8

2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing. 2passstools:使用机器学习过滤剪接连接的两遍比对提高了长读RNA测序中内含子检测的准确性。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-03-01 DOI: 10.1186/s13059-021-02296-0

Matthew T Parker, Katarzyna Knop, Geoffrey J Barton, Gordon G Simpson

引用次数: 13

Re-evaluating experimental validation in the Big Data Era: a conceptual argument. 重新评估大数据时代的实验验证:一个概念上的争论。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-02-24 DOI: 10.1186/s13059-021-02292-4

Mohieddin Jafari, Yuanfang Guan, David C Wedge, Naser Ansari-Pour

引用次数: 8

MEDALT: single-cell copy number lineage tracing enabling gene discovery. MEDALT：通过单细胞拷贝数系谱追踪发现基因。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-02-23 DOI: 10.1186/s13059-021-02291-5

Fang Wang, Qihan Wang, Vakul Mohanty, Shaoheng Liang, Jinzhuang Dou, Jincheng Han, Darlan Conterno Minussi, Ruli Gao, Li Ding, Nicholas Navin, Ken Chen

引用次数: 0

Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase. 使用纳米孔长读数和NanoMethPhase的百万级甲基化分相。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-02-22 DOI: 10.1186/s13059-021-02283-5

Vahid Akbari, Jean-Michel Garant, Kieran O'Neill, Pawan Pandoh, Richard Moore, Marco A Marra, Martin Hirst, Steven J M Jones

引用次数: 25

scSorter: assigning cells to known cell types according to marker genes. scSorter：根据标记基因将细胞归入已知的细胞类型。

IF 12.3 1区生物学

Genome Biology Pub Date : 2021-02-22 DOI: 10.1186/s13059-021-02281-7

Hongyu Guo, Jun Li

引用次数: 0

FlsnRNA-seq: protoplasting-free full-length single-nucleus RNA profiling in plants. FlsnRNA-seq:植物原生质体无全长单核RNA分析。