Acta Clinica Belgica最新文献_第9页

A case of transient lymphangiectasis of the penis. 阴茎暂时性淋巴管扩张1例。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-05-20 DOI: 10.1179/2295333714Y.0000000028

A Misson, A C Deswysen, D Tennstedt, X Muschart

引用次数: 1

An unexpected complication of bacillus Calmette-Guérin therapy. 卡介苗-谷氨酰胺治疗的意外并发症。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-05-20 DOI: 10.1179/2295333714Y.0000000032

H Yildiz, G Colin, M Lambert

{"title":"An unexpected complication of bacillus Calmette-Guérin therapy.","authors":"H Yildiz, G Colin, M Lambert","doi":"10.1179/2295333714Y.0000000032","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000032","url":null,"abstract":"A 78-year-old man presented with a history of fever and night sweats of 1-month duration. His relevant medical history was a transitional-cell bladder cancer treated with intravesical instillation of bacillus Calmette–Guérin (BCG) 5 months previously. Abdominal palpation revealed a pulsatile mass in the left lower quadrant. Laboratory tests only showed an elevated C-reactive protein at 5.7 mg/dl. Contrast-enhanced CT scan of the abdomen demonstrated a saccular aneurysm of the infra-renal aorta (Fig. 1) suggestive of mycotic aneurysm. An aneurysmal resection was then performed. Aerobic and anaerobic culture of the aortic tissue remained negative but a Ziehl–Nielsen stain was positive consistent with a mycobacterial infection. Acid-fast culture and PCR were positive for Mycobacterium bovis. The diagnosis of mycotic aneurysma following intravesical BCG therapy was then retained. Vascular complications after intravesical instillation of BCG, a live attenuated strain of Mycobacterium bovis, are extremely rare. Haematogenous or lymphatic spread is the most common hypothesis proposed to explain an arterial infection by M. bovis. Both medical and surgical approach are requested in the management of BCGinduced mycotic aneurysm. A combination with at least three antituberculous agents for 9–12 months is recommended. Pyrazinamide should not be used due to widespread resistance of M. bovis.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"69 4","pages":"312"},"PeriodicalIF":1.6,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32355113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Bluish vomiting: a rare clinical presentation of poisoning. 蓝色呕吐:中毒的罕见临床表现。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-05-20 DOI: 10.1179/2295333714Y.0000000033

J Higny, D Vanpee, C Boulouffe

引用次数: 8

Laboratory diagnosis of schistosomiasis and Katayama syndrome in returning travellers. 返国旅行者血吸虫病和片山综合征的实验室诊断。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-06-10 DOI: 10.1179/2295333714Y.0000000039

B Van Meensel, E Van Wijngaerden, J Verhaegen, W E Peetermans, M L Lontie, C Ripert

{"title":"Laboratory diagnosis of schistosomiasis and Katayama syndrome in returning travellers.","authors":"B Van Meensel, E Van Wijngaerden, J Verhaegen, W E Peetermans, M L Lontie, C Ripert","doi":"10.1179/2295333714Y.0000000039","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000039","url":null,"abstract":"The gold standard for laboratory diagnosis of schistosomiasis is the presence of typical eggs in stool or urine. The laboratory diagnosis of schistosomiasis and Katayama syndrome in returning travellers is difficult because the number of excreted eggs is often very limited. In early infections and in patients with only a few contacts with contaminated water, the total number of parasites, migrating larvae or schistosomulae, and adult worms, is very low. Eggs can only be found in faeces or urine when there is at least one pair of adult worms at the final location. The number of parasites increases as a function of the number of contacts with infected water. The exact latency between contamination and egg production is unknown. It is estimated that excretion of eggs starts after 40-50 days. The specific diagnosis of early schistosomiasis and Katayama fever relies essentially on serologic tests or preferably on PCR (if available). These assays are much more sensitive (up to four times) in the early phase of schistosomiasis than microscopic examination for typical eggs. Eosinophilia (sometimes exceeding 50%) is often present in patients with acute schistosomiasis (Katayama fever), but may be limited or absent in late fibrotic manifestations of the disease. ","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"69 4","pages":"267-72"},"PeriodicalIF":1.6,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32411839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Thoracopulmonary actinomycosis, a case report of a 42-year-old man with coughing and a bump in his right axilla. 胸肺放线菌病，报告一例42岁男性咳嗽及右腋窝肿块。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-06-10 DOI: 10.1179/2295333714Y.0000000014

C B Seghers, I Stappaerts

引用次数: 0

Postprandial reactive hypoglycaemia in a very old patient. 高龄患者餐后反应性低血糖1例。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-06-10 DOI: 10.1179/2295333714Y.0000000026

C Deliens, Cl Losseau, B Vandeleene, B Boland

{"title":"Postprandial reactive hypoglycaemia in a very old patient.","authors":"C Deliens, Cl Losseau, B Vandeleene, B Boland","doi":"10.1179/2295333714Y.0000000026","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000026","url":null,"abstract":"Objective and importance: Postprandial reactive hypoglycaemia (PRH) is a clinical syndrome characterized by the recurrence of symptomatic hypoglycaemia during postprandial periods. PRH remains a diagnostic challenge for clinicians, because of its atypical manifestations and low prevalence, especially in older persons.Clinical presentation: We report the diagnostic work-up of severe hypoglycaemic episodes in a very old patient in whom the diagnosis of PRH was made.Intervention: We prescribed acarbose, an alpha-glucosidase inhibitor, to this patient to prevent the recurrence of hypoglycaemic episodes. Four years later, acarbose was always used and no further episode of hypoglycaemia had occurred. Based on the literature, we discuss the limited value of endocrine tests as well as the efficacy of the therapeutic approaches.Conclusion: Prescription of acarbose is useful in addition to nutritional education, the corner stone of the treatment, to avoid the recurrence of severe hypoglycaemic events due to PRH.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"69 4","pages":"290-3"},"PeriodicalIF":1.6,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32411837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Muscle metastasis from non-small cell lung cancer: two cases and literature review. 非小细胞肺癌肌肉转移2例并文献复习。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-05-29 DOI: 10.1179/2295333714Y.0000000035

Y Tezcan, M Koc

引用次数: 8

Serum angiostatin levels in patients with Behçet's disease: does angiogenesis play a role in the pathogenesis of Behçet's disease? behet病患者血清血管抑制素水平:血管生成在behet病的发病机制中起作用吗?

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 DOI: 10.1179/2295333714Y.0000000030

D Keskin, G Keskin, A Inal, L Ozışık

{"title":"Serum angiostatin levels in patients with Behçet's disease: does angiogenesis play a role in the pathogenesis of Behçet's disease?","authors":"D Keskin, G Keskin, A Inal, L Ozışık","doi":"10.1179/2295333714Y.0000000030","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000030","url":null,"abstract":"Angiogenesis plays an important role in the pathogenesis of inflammatory diseases, but the possible role of angiogenesis in Behçet's disease (BD) has not yet been studied. The aim of this study was to determine angiostatin levels in patients with BD and the role of angiogenesis in the pathogenesis of the disease. Thirty-seven patients with BD (mean age: 28·6±5·4 years, mean disease duration: 9·3±3·7 years) and 18 healthy controls were enrolled to the study. Twenty-four patients were in active and 13 patients were in inactive stage of the disease. The mean serum angiostatin level of patients with BD was 113·9±53·2 and 60·7±20·1 ng/ml in healthy controls. The mean serum angiostatin level was 142·7±43·1 ng/ml in active and 86·9±15·5 ng/ml in inactive patients with BD. Serum angiostatin levels were significantly high in patients with BD compared with healthy controls (P<0·001) and it was significantly high in active patients compared with inactive patients with BD (P<0·001). In inactive patients with BD, serum angiostatin concentrations were found to be higher compared with healthy controls (P<0·01). In active BD patients, the mean serum angiostatin level was correlated with the deep vein thrombosis (r = 0·482, P = 0·05), uveitis (r = 0·582, P = 0·01), and arthritis (r = 0·492, P = 0·05). According to these results; elevated serum angiostatin levels in patients with BD suggest the possible role of angiogenesis in the pathogenesis of the disease and its high levels in inactive Behçet's patients is related with the continuous activation of the disease even in the subclinical period. ","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"69 4","pages":"246-50"},"PeriodicalIF":1.6,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32496095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

HIV disclosure in the workplace. 在工作场所披露艾滋病毒。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-06-01 Epub Date: 2014-03-13 DOI: 10.1179/2295333714Y.0000000013

S Degroote, D Vogelaers, R Koeck, R Borms, L De Meulemeester, D Vandijck

{"title":"HIV disclosure in the workplace.","authors":"S Degroote, D Vogelaers, R Koeck, R Borms, L De Meulemeester, D Vandijck","doi":"10.1179/2295333714Y.0000000013","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000013","url":null,"abstract":"Objectives: As HIV is currently a chronic and manageable disease, an increasing amount of people living with HIV (PLHIV) are (again) active on the labour market. Since research on this topic is scarce, this study aimed to explore experiences of PLHIV in the workplace, especially concerning disclosure and adherence to antiretroviral therapy.Methods: A questionnaire was developed and validated in collaboration with Sensoa (Flemish expertise centre for sexual health) and participants were recruited using flyers and announcements on websites.Results: A total of 54 PLHIV completed the questionnaire, among whom 50 (92·6%) males. Half of the participants did not disclose their HIV status in the workplace, mostly due to being afraid of social or professional consequences. Those who disclosed, reported no changes in the workplace or even reported receiving more empathy. A minority of participants have to take antiretroviral medication at work and they reported no particular problems related to medication intake.Conclusion: Despite improved solidarity and information campaigns, many PLHIV still do not disclose their HIV status in the workplace, most frequently due to fear for discrimination. More actions are warranted, as well as addressing possible self-stigma. Adherence to antiretroviral therapy in the workplace posed little or no problems.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"69 3","pages":"191-3"},"PeriodicalIF":1.6,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32335161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Survival of patients with metastatic breast cancer: a single-centre experience. 转移性乳腺癌患者的生存:单中心经验。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-06-01 Epub Date: 2014-03-18 DOI: 10.1179/2295333714Y.0000000016

R D'hondt, I Spoormans, N Neyens, N Mortier, F Van Aelst

{"title":"Survival of patients with metastatic breast cancer: a single-centre experience.","authors":"R D'hondt, I Spoormans, N Neyens, N Mortier, F Van Aelst","doi":"10.1179/2295333714Y.0000000016","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000016","url":null,"abstract":"Metastatic breast cancer (MBC) remains an incurable disease, despite major advances in the treatment in the past 10-12 years. Data on real life overall survival in a non-selected group containing all metastatic breast cancer patients are hard to find in the literature, as is the correlation of their survival with prognostic factors and treatment. This article provides overall survival data for all patients treated for MBC in a single-centre non-academic hospital. Survival data have been correlated with frequently used prognostic factors (subtype, age at diagnosis, M-status at diagnosis, metastases-free interval, and grade). It also gives an insight in the treatments given to and response rates in this population of MBC patients without selection bias representing the real life situation. A total of 169 patients were analysed. Mean survival from metastases is 31·8 months. Overall survival is better for the luminal subtypes, for younger age, for patients with a longer metastases-free interval, and for a lower grade. A small difference in survival has been seen in favour of the patients who represent immediately with metastases. With a larger sample size, we expect these factors to be prognostic significant. The luminal subtypes have a clear predisposition to metastasize in the bone, whereas visceral metastases occur more frequently and earlier in the hormone receptor-negative tumours. Brain metastases do occur in about half of the triple negative tumours and Her2/neu-positive tumours. Overall response rate to first-line chemotherapy was 56% in consecutive lines of treatment, a continuous clinical benefit exceeding 50% when selecting fit patients. This article represents a unique and valuable description of medical oncologists' real-life daily practice in MBC patients, with a clinical outcome that certainly compares to the sparse data provided in the literature. ","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":"69 3","pages":"194-9"},"PeriodicalIF":1.6,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32184734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3