Acta Clinica Belgica最新文献_第9页

Bluish vomiting: a rare clinical presentation of poisoning. 蓝色呕吐:中毒的罕见临床表现。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-05-20 DOI: 10.1179/2295333714Y.0000000033

J Higny, D Vanpee, C Boulouffe

引用次数: 8

Laboratory diagnosis of schistosomiasis and Katayama syndrome in returning travellers. 返国旅行者血吸虫病和片山综合征的实验室诊断。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-06-10 DOI: 10.1179/2295333714Y.0000000039

B Van Meensel, E Van Wijngaerden, J Verhaegen, W E Peetermans, M L Lontie, C Ripert

{"title":"Laboratory diagnosis of schistosomiasis and Katayama syndrome in returning travellers.","authors":"B Van Meensel, E Van Wijngaerden, J Verhaegen, W E Peetermans, M L Lontie, C Ripert","doi":"10.1179/2295333714Y.0000000039","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000039","url":null,"abstract":"The gold standard for laboratory diagnosis of schistosomiasis is the presence of typical eggs in stool or urine. The laboratory diagnosis of schistosomiasis and Katayama syndrome in returning travellers is difficult because the number of excreted eggs is often very limited. In early infections and in patients with only a few contacts with contaminated water, the total number of parasites, migrating larvae or schistosomulae, and adult worms, is very low. Eggs can only be found in faeces or urine when there is at least one pair of adult worms at the final location. The number of parasites increases as a function of the number of contacts with infected water. The exact latency between contamination and egg production is unknown. It is estimated that excretion of eggs starts after 40-50 days. The specific diagnosis of early schistosomiasis and Katayama fever relies essentially on serologic tests or preferably on PCR (if available). These assays are much more sensitive (up to four times) in the early phase of schistosomiasis than microscopic examination for typical eggs. Eosinophilia (sometimes exceeding 50%) is often present in patients with acute schistosomiasis (Katayama fever), but may be limited or absent in late fibrotic manifestations of the disease. ","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32411839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Muscle metastasis from non-small cell lung cancer: two cases and literature review. 非小细胞肺癌肌肉转移2例并文献复习。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-05-29 DOI: 10.1179/2295333714Y.0000000035

Y Tezcan, M Koc

引用次数: 8

Thoracopulmonary actinomycosis, a case report of a 42-year-old man with coughing and a bump in his right axilla. 胸肺放线菌病，报告一例42岁男性咳嗽及右腋窝肿块。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-06-10 DOI: 10.1179/2295333714Y.0000000014

C B Seghers, I Stappaerts

引用次数: 0

Postprandial reactive hypoglycaemia in a very old patient. 高龄患者餐后反应性低血糖1例。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 Epub Date: 2014-06-10 DOI: 10.1179/2295333714Y.0000000026

C Deliens, Cl Losseau, B Vandeleene, B Boland

{"title":"Postprandial reactive hypoglycaemia in a very old patient.","authors":"C Deliens, Cl Losseau, B Vandeleene, B Boland","doi":"10.1179/2295333714Y.0000000026","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000026","url":null,"abstract":"Objective and importance: Postprandial reactive hypoglycaemia (PRH) is a clinical syndrome characterized by the recurrence of symptomatic hypoglycaemia during postprandial periods. PRH remains a diagnostic challenge for clinicians, because of its atypical manifestations and low prevalence, especially in older persons.Clinical presentation: We report the diagnostic work-up of severe hypoglycaemic episodes in a very old patient in whom the diagnosis of PRH was made.Intervention: We prescribed acarbose, an alpha-glucosidase inhibitor, to this patient to prevent the recurrence of hypoglycaemic episodes. Four years later, acarbose was always used and no further episode of hypoglycaemia had occurred. Based on the literature, we discuss the limited value of endocrine tests as well as the efficacy of the therapeutic approaches.Conclusion: Prescription of acarbose is useful in addition to nutritional education, the corner stone of the treatment, to avoid the recurrence of severe hypoglycaemic events due to PRH.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32411837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Serum angiostatin levels in patients with Behçet's disease: does angiogenesis play a role in the pathogenesis of Behçet's disease? behet病患者血清血管抑制素水平:血管生成在behet病的发病机制中起作用吗?

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-08-01 DOI: 10.1179/2295333714Y.0000000030

D Keskin, G Keskin, A Inal, L Ozışık

{"title":"Serum angiostatin levels in patients with Behçet's disease: does angiogenesis play a role in the pathogenesis of Behçet's disease?","authors":"D Keskin, G Keskin, A Inal, L Ozışık","doi":"10.1179/2295333714Y.0000000030","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000030","url":null,"abstract":"Angiogenesis plays an important role in the pathogenesis of inflammatory diseases, but the possible role of angiogenesis in Behçet's disease (BD) has not yet been studied. The aim of this study was to determine angiostatin levels in patients with BD and the role of angiogenesis in the pathogenesis of the disease. Thirty-seven patients with BD (mean age: 28·6±5·4 years, mean disease duration: 9·3±3·7 years) and 18 healthy controls were enrolled to the study. Twenty-four patients were in active and 13 patients were in inactive stage of the disease. The mean serum angiostatin level of patients with BD was 113·9±53·2 and 60·7±20·1 ng/ml in healthy controls. The mean serum angiostatin level was 142·7±43·1 ng/ml in active and 86·9±15·5 ng/ml in inactive patients with BD. Serum angiostatin levels were significantly high in patients with BD compared with healthy controls (P<0·001) and it was significantly high in active patients compared with inactive patients with BD (P<0·001). In inactive patients with BD, serum angiostatin concentrations were found to be higher compared with healthy controls (P<0·01). In active BD patients, the mean serum angiostatin level was correlated with the deep vein thrombosis (r = 0·482, P = 0·05), uveitis (r = 0·582, P = 0·01), and arthritis (r = 0·492, P = 0·05). According to these results; elevated serum angiostatin levels in patients with BD suggest the possible role of angiogenesis in the pathogenesis of the disease and its high levels in inactive Behçet's patients is related with the continuous activation of the disease even in the subclinical period. ","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32496095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

HIV disclosure in the workplace. 在工作场所披露艾滋病毒。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-06-01 Epub Date: 2014-03-13 DOI: 10.1179/2295333714Y.0000000013

S Degroote, D Vogelaers, R Koeck, R Borms, L De Meulemeester, D Vandijck

{"title":"HIV disclosure in the workplace.","authors":"S Degroote, D Vogelaers, R Koeck, R Borms, L De Meulemeester, D Vandijck","doi":"10.1179/2295333714Y.0000000013","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000013","url":null,"abstract":"Objectives: As HIV is currently a chronic and manageable disease, an increasing amount of people living with HIV (PLHIV) are (again) active on the labour market. Since research on this topic is scarce, this study aimed to explore experiences of PLHIV in the workplace, especially concerning disclosure and adherence to antiretroviral therapy.Methods: A questionnaire was developed and validated in collaboration with Sensoa (Flemish expertise centre for sexual health) and participants were recruited using flyers and announcements on websites.Results: A total of 54 PLHIV completed the questionnaire, among whom 50 (92·6%) males. Half of the participants did not disclose their HIV status in the workplace, mostly due to being afraid of social or professional consequences. Those who disclosed, reported no changes in the workplace or even reported receiving more empathy. A minority of participants have to take antiretroviral medication at work and they reported no particular problems related to medication intake.Conclusion: Despite improved solidarity and information campaigns, many PLHIV still do not disclose their HIV status in the workplace, most frequently due to fear for discrimination. More actions are warranted, as well as addressing possible self-stigma. Adherence to antiretroviral therapy in the workplace posed little or no problems.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32335161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Survival of patients with metastatic breast cancer: a single-centre experience. 转移性乳腺癌患者的生存:单中心经验。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-06-01 Epub Date: 2014-03-18 DOI: 10.1179/2295333714Y.0000000016

R D'hondt, I Spoormans, N Neyens, N Mortier, F Van Aelst

{"title":"Survival of patients with metastatic breast cancer: a single-centre experience.","authors":"R D'hondt, I Spoormans, N Neyens, N Mortier, F Van Aelst","doi":"10.1179/2295333714Y.0000000016","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000016","url":null,"abstract":"Metastatic breast cancer (MBC) remains an incurable disease, despite major advances in the treatment in the past 10-12 years. Data on real life overall survival in a non-selected group containing all metastatic breast cancer patients are hard to find in the literature, as is the correlation of their survival with prognostic factors and treatment. This article provides overall survival data for all patients treated for MBC in a single-centre non-academic hospital. Survival data have been correlated with frequently used prognostic factors (subtype, age at diagnosis, M-status at diagnosis, metastases-free interval, and grade). It also gives an insight in the treatments given to and response rates in this population of MBC patients without selection bias representing the real life situation. A total of 169 patients were analysed. Mean survival from metastases is 31·8 months. Overall survival is better for the luminal subtypes, for younger age, for patients with a longer metastases-free interval, and for a lower grade. A small difference in survival has been seen in favour of the patients who represent immediately with metastases. With a larger sample size, we expect these factors to be prognostic significant. The luminal subtypes have a clear predisposition to metastasize in the bone, whereas visceral metastases occur more frequently and earlier in the hormone receptor-negative tumours. Brain metastases do occur in about half of the triple negative tumours and Her2/neu-positive tumours. Overall response rate to first-line chemotherapy was 56% in consecutive lines of treatment, a continuous clinical benefit exceeding 50% when selecting fit patients. This article represents a unique and valuable description of medical oncologists' real-life daily practice in MBC patients, with a clinical outcome that certainly compares to the sparse data provided in the literature. ","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32184734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Prolonged ileus with pneumatosis cystoides intestinalis. 长时间肠梗阻伴肠囊性肺肿。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-06-01 Epub Date: 2014-04-02 DOI: 10.1179/2295333714Y.0000000021

C-T Chao

{"title":"Prolonged ileus with pneumatosis cystoides intestinalis.","authors":"C-T Chao","doi":"10.1179/2295333714Y.0000000021","DOIUrl":"https://doi.org/10.1179/2295333714Y.0000000021","url":null,"abstract":"A 40-year-old woman with rectal cancer visited our emergency department for abdominal pain and vomiting. She had received operation and chemoradiotherapy 6 months ago with subsequent lymph node recurrence and obstructive uropathy. Ureteral stenting and pecutaneous nephrostomy were performed for relief then. Her abdominal symptoms were attributed to ileus, and consulting surgeon recommended against re-operation owing to poor performance status. Her ileus fluctuated in severity, with recurrent bacteremia. An abdominal film 3 weeks later revealed radiolucent areas surrounding the entire bowel contour (Fig. 1). Abdominal computed tomography demonstrated prominent pneumatosis cystoides intestinalis involving colon and small bowel (Fig. 1). Hypotension and profound metabolic acidosis ensued with consciousness loss, and a family decision was made not to resuscitate her. She passed away 1 day later. Pneumatosis cystoides intestinalis presents as air collection in bowel wall layers, and can be innocent as in idiopathic or post-endoscopic cases. Other causes could be life-threatening. The main aetiologies include mesenteric vascular diseases with bowel ischaemia, followed by inflammatory bowel diseases and intestinal obstruction/infection. Small intestine and right side colon are the most common sites involved. Our patient presumably suffered from Correspondence to: C.-T. Chao, Department of Internal Medicine, National Taiwan University Hospital Jin-Shan Branch, No. 51, Nan-Shih, Jin-Shan District, New Taipei City, Taiwan. Email: b88401084@gmail.com Figure 1 (Left) Abominal plain film disclosed clear contour of the, while colonic segments from right (curved arrow), transverse to left colon (straight arrow) as contrasted from radiolucent bowel wall gas. Small bowel wall pneumatosis was also identified. (Right) Computed tomography demonstrated the extensive bowel gas over small bowel and colon.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/2295333714Y.0000000021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32228671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology of infective endocarditis in a large Belgian non-referral hospital. 比利时一家大型非转诊医院感染性心内膜炎的流行病学研究。

IF 1.6 4区医学

Acta Clinica Belgica Pub Date : 2014-06-01 Epub Date: 2014-04-25 DOI: 10.1179/0001551214Z.00000000046

K Poesen, H Pottel, J Colaert, C De Niel

{"title":"Epidemiology of infective endocarditis in a large Belgian non-referral hospital.","authors":"K Poesen, H Pottel, J Colaert, C De Niel","doi":"10.1179/0001551214Z.00000000046","DOIUrl":"https://doi.org/10.1179/0001551214Z.00000000046","url":null,"abstract":"Objectives: Guidelines for diagnosis of infective endocarditis are largely based upon epidemiological studies in referral hospitals. Referral bias, however, might impair the validity of guidelines in non-referral hospitals. Recent studies in non-referral care centres on infective endocarditis are sparse. We conducted a retrospective epidemiological study on infective endocarditis in a large non-referral hospital in a Belgian city (Kortrijk).Methods: The medical record system was searched for all cases tagged with a putative diagnosis of infective endocarditis in the period 2003-2010. The cases that fulfilled the modified Duke criteria for probable or definite infective endocarditis were included.Results: Compared to referral centres, an older population with infective endocarditis, and fewer predisposing cardiac factors and catheter-related infective endocarditis is seen in our population. Our patients have fewer prosthetic valve endocarditis as well as fewer staphylococcal endocarditis. Our patients undergo less surgery, although mortality rate seems to be highly comparable with referral centres, with nosocomial infective endocarditis as an independent predictor of mortality.Conclusion: The present study suggests that characteristics of infective endocarditis as well as associative factors might differ among non-referral hospitals and referral hospitals.","PeriodicalId":48865,"journal":{"name":"Acta Clinica Belgica","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/0001551214Z.00000000046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32288433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12