{"title":"Anaphylactic shock induced by HEC® ointment: A CARE case report.","authors":"L de Villars, M Douet, C Aussedat","doi":"10.1016/j.anorl.2025.07.003","DOIUrl":"https://doi.org/10.1016/j.anorl.2025.07.003","url":null,"abstract":"<p><strong>Introduction: </strong>HEC® phenazone-tannin-witch hazel ointment is widely used in the treatment of epistaxis, with few adverse effects. Anaphylactic shock after packing with HEC® ointment has, to the authors' knowledge, never previously been reported.</p><p><strong>Case report: </strong>A 53 year-old male presented with massive epistaxis requiring packing after cauterization. After packing with HEC® ointment, the patient experienced grade 5 anaphylactic shock, requiring admission to intensive care. The outcome was ultimately favorable.</p><p><strong>Conclusion: </strong>Potential allergy to the ingredients of HEC® ointment should be ascertained before application, to avoid serious reactions.</p>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Rodríguez Lorenzana, Á Iglesias Castro, F Vázquez de la Iglesia, A Fernández Tenreiro
{"title":"Iatrogenic tracheal injury following laser cordotomy via tracheostomy.","authors":"P Rodríguez Lorenzana, Á Iglesias Castro, F Vázquez de la Iglesia, A Fernández Tenreiro","doi":"10.1016/j.anorl.2025.07.001","DOIUrl":"https://doi.org/10.1016/j.anorl.2025.07.001","url":null,"abstract":"","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter on the article “Deciding whether to do elective neck dissection in patients with salivary gland tumors with no evidence of neck lymph node metastasis” by Sanabria A, et al. Eur Ann Otorhinolaryngol Head Neck Dis 2025;142:135–42","authors":"E. Chabrillac , S. Vergez , B. Baujat , N. Fakhry","doi":"10.1016/j.anorl.2025.06.005","DOIUrl":"10.1016/j.anorl.2025.06.005","url":null,"abstract":"","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 221-222"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Boghossian, M.M. Cervinia, D.H. Nguyen, D. Garcia, H. Mirghani, O. Laccourreye
{"title":"A comparative STROBE analysis of 10-year oncologic results of SCPL-CHEP and endoscopic CO2 laser cordectomy for cT2N0M0 glottic squamous cell carcinoma","authors":"A. Boghossian, M.M. Cervinia, D.H. Nguyen, D. Garcia, H. Mirghani, O. Laccourreye","doi":"10.1016/j.anorl.2025.04.006","DOIUrl":"10.1016/j.anorl.2025.04.006","url":null,"abstract":"<div><h3>Objective</h3><div>To compare 10-year oncologic results of supracricoid partial laryngectomy and cricohyoidoepiglottopexy (SCPL-CHEP) versus CO<sub>2</sub> laser cordectomy (LC) for cT2N0M0 glottic squamous cell carcinoma (SCC).</div></div><div><h3>Material and method</h3><div>Retrospective observational analysis of an inception cohort of 57 patients with isolated cT2N0M0 glottic SCC consecutively managed at a French university teaching otorhinolaryngology department during the years 1993–2013: 33 with SCPL-CHEP and 24 with LC. In all, 93% and 81% of patients were followed for respectively at least 5 years, or 10 years or until death. The main endpoint was 10-year actuarial overall and disease-free survival. Secondary endpoints comprised cause of death, 10-year actuarial local control, and 10-year laryngeal preservation estimates.</div></div><div><h3>Results</h3><div>Ten-year survival was 58% whichever the surgical technique. Ten-year disease-free survival was 87% after SCPL-CHEP and 71% after LC (<em>P</em> <!-->=<!--> <!-->0.15). Death related to SCC occurred in 3 patients after LC but was not encountered after SCPL-CHEP. Ten-year local control differed: 100% after SCPL-CHEP versus 65% after LC, with 96% overall local control after salvage treatment. Ten-year laryngeal preservation differed: 97% after SCPL-CHEP versus 74% after LC (<em>P</em> <!-->=<!--> <!-->0.03).</div></div><div><h3>Conclusions</h3><div>In patients with cT2N0M0 glottic SCC considered amenable to partial laryngeal surgery, the present long-term data should lead head and neck surgeons to discuss the benefits and pitfalls of both LC and SCPL-CHEP.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 185-190"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Asbestos and head-and-neck cancer: An important association for patient monitoring and compensation","authors":"C.-A. Righini , T. Doutrebente , C. Fabre","doi":"10.1016/j.anorl.2025.06.006","DOIUrl":"10.1016/j.anorl.2025.06.006","url":null,"abstract":"","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 169-170"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Piccin , F. Contedini , V. Sciarretta , V. Pinto
{"title":"Laryngotracheal and esophageal functional reconstruction using a single anterolateral thigh flap","authors":"O. Piccin , F. Contedini , V. Sciarretta , V. Pinto","doi":"10.1016/j.anorl.2024.07.011","DOIUrl":"10.1016/j.anorl.2024.07.011","url":null,"abstract":"<div><div>The main goal for treatment of locally advanced thyroid carcinoma invading the laryngotracheal and esophageal complex, is radical surgical excision and reconstruction of a functional aerodigestive tract. We describe a challenging surgical technique in which a wide laryngotracheal and esophageal defect was functionally reconstructed using a single anterolateral thigh flap. This can represent a good option for a tailored functional reconstruction of extended defects of the aerodigestive tract.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 205-212"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Caillaud , L. Pellé-Boudeau , M. Férrandière , D. Bakhos , E. Lescanne , F. Micaletti
{"title":"Awake stapedectomy under hypnoanalgesia: Efficacy and safety in the treatment of otosclerosis","authors":"E. Caillaud , L. Pellé-Boudeau , M. Férrandière , D. Bakhos , E. Lescanne , F. Micaletti","doi":"10.1016/j.anorl.2025.04.001","DOIUrl":"10.1016/j.anorl.2025.04.001","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the efficacy and safety of awake stapedectomy under hypnoanalgesia (HA) compared to general anesthesia (GA) and local anesthesia (LA) in patients with otosclerosis.</div></div><div><h3>Methods</h3><div>A single-center retrospective study included 131 adult patients (mean age: 49 years; 78% female) who underwent laser stapedectomy between 2020 and 2022: 58 GA, 23 LA, 50 HA. Primary outcome measures comprised operative room occupancy time, anesthetic consumption, and postoperative audiometric results.</div></div><div><h3>Results</h3><div>HA significantly reduced operative room occupancy time (73.5<!--> <!-->±<!--> <!-->18.6<!--> <!-->min vs 103.7<!--> <!-->±<!--> <!-->24.6<!--> <!-->min in GA, <em>P</em> <!--><<!--> <!-->0.001; vs 81.8<!--> <!-->±<!--> <!-->20.5<!--> <!-->min in LA, <em>P</em> <!-->=<!--> <!-->0.092), stapedectomy duration (39.9<!--> <!-->±<!--> <!-->12.4<!--> <!-->min vs 48.9<!--> <!-->±<!--> <!-->21.5<!--> <!-->min in GA, <em>P</em> <!-->=<!--> <!-->0.0252; vs 38.9<!--> <!-->±<!--> <!-->13.2<!--> <!-->min in LA, <em>P</em> <!-->=<!--> <!-->0.4601), preoperative time (30.2<!--> <!-->±<!--> <!-->9.5<!--> <!-->min vs 45.7<!--> <!-->±<!--> <!-->9.5<!--> <!-->min in GA, <em>P</em> <!--><<!--> <!-->0.001; vs 38.6<!--> <!-->±<!--> <!-->12.2<!--> <!-->min in LA, <em>P</em> <!-->=<!--> <!-->0.0022), and recovery room time (26<!--> <!-->±<!--> <!-->15.1<!--> <!-->min vs 67.5<!--> <!-->±<!--> <!-->20.7<!--> <!-->min in GA, <em>P</em> <!--><<!--> <!-->0.001; vs 47.4<!--> <!-->±<!--> <!-->20.7<!--> <!-->min in LA, <em>P</em> <!--><<!--> <!-->0.001). HA also significantly reduced remifentanil consumption (169.8<!--> <!-->±<!--> <!-->101.6<!--> <!-->μg vs 848.6<!--> <!-->±<!--> <!-->308.8<!--> <!-->μg in GA, <em>P</em> <!--><<!--> <!-->0.001; vs 323.9<!--> <!-->±<!--> <!-->94.4<!--> <!-->μg in LA, <em>P</em> <!--><<!--> <!-->0.001). Postoperative audiometric outcomes showed no significant differences between groups.</div></div><div><h3>Conclusion</h3><div>Hypnoanalgesia for awake stapedectomy provided significantly greater efficacy compared to general anesthesia, reducing operative time and anesthetic consumption, with comparable audiometric outcomes.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 179-184"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trigeminal cervical complex: A neural network affecting the head and neck","authors":"F. Bou Malhab , J. Hosri , G. Zaytoun , U. Hadi","doi":"10.1016/j.anorl.2024.09.008","DOIUrl":"10.1016/j.anorl.2024.09.008","url":null,"abstract":"<div><h3>Objectives</h3><div>To introduce the trigeminal cervical complex (TCC) as a comprehensive framework for understanding the anatomical and functional scope of the afferences and efferences of the trigeminal nerve and explaining common otolaryngologic symptoms, including head and neck myofascial pain syndrome. Additionally, it explores how the bidirectional transmission of neurotransmitters contributes to the sensitization of the TCC and motor nuclei.</div></div><div><h3>Methods</h3><div>The study was conducted as a narrative review. The authors performed a comprehensive search of multiple databases, including Medline/OVID, Embase, Scopus, and PubMed, covering publications from inception until August 2023. Both keywords and medical subject headings related to the TCC were utilized in the search. Information from 66 studies was extracted based on predetermined inclusion and exclusion criteria.</div></div><div><h3>Results</h3><div>This review discusses the multiple afferent connections from cranial nerves, specifically VII, IX, X, and XI, to the TCC, and their respective efferent pathways. These connections may explain various clinical manifestations in the head and neck that cannot be attributed to other medical conditions. Additionally, the review highlights the dual sensory and motor nature of cranial nerves, emphasizing the bidirectional transmission of neurotransmitters in head and neck areas, which leads to the sensitization of both the TCC and motor nuclei innervating the cervicofacial muscles.</div></div><div><h3>Conclusion</h3><div>The authors hypothesize that the central and peripheral sensitization and the intricate connections of the TCC can elucidate the pathophysiology of conditions such as otalgia, tinnitus, hearing loss, vertigo, headache, cervicogenic dizziness, bruxism, and other symptoms affecting the head and neck.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 191-200"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing the diagnostic capacity of artificial intelligence chatbots for dysphonia types: Model development and validation","authors":"S. Saeedi , M. Aghajanzadeh","doi":"10.1016/j.anorl.2025.01.001","DOIUrl":"10.1016/j.anorl.2025.01.001","url":null,"abstract":"<div><h3>Purpose</h3><div>User-friendly artificial intelligence (AI) chatbots are increasingly being explored to assist healthcare teams in their decision-making processes. As accurate diagnosis in all medical fields is vital in treatment planning, this research seeks to explore the function of two specific AI chatbots, ChatGPT and Perplexity AI, in distinguishing the various types of dysphonia (organic, functional, and neurological).</div></div><div><h3>Material and methods</h3><div>In experiment 1, a script combining voice self-assessments plus the acoustic analysis, and in experiment 2, only the acoustic analysis of 37 dysphonic patients was fed into the ChatGPT and Perplexity AI chatbots specifying the type and asked to develop a complex AI-based model to determine dysphonia type. Then, the same process was redone with data from a sample of 27 other patients as a test.</div></div><div><h3>Results</h3><div>Although ChatGPT could not analyze the data and only provided guidance, the Cohen's Kappa agreement between experts’ diagnoses and Perplexity AI diagnoses in experiment 1 (<em>P</em> <!-->=<!--> <!-->0.773) and experiment 2 (<em>P</em> <!-->=<!--> <!-->0.067) lacked statistically significance.</div></div><div><h3>Conclusion</h3><div>Regarding the preliminary poor performance of AI chatbots in differential diagnosis of dysphonia type, it is not currently recommended to use them in clinical settings. However, modifications in AI chatbots in the future might provide more promising results in determining the dysphonia type. Further research is needed to shed light on AI chatbots ability in voice clinics.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 171-178"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scientific and skeptical medical writing","authors":"F. Simon","doi":"10.1016/j.anorl.2024.11.002","DOIUrl":"10.1016/j.anorl.2024.11.002","url":null,"abstract":"","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 4","pages":"Pages 167-168"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}