European Annals of Otorhinolaryngology-Head and Neck Diseases最新文献

Acute intestinal obstruction due to duodenal metastasis of laryngeal squamous cell carcinoma: A CARE case report.

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-13 DOI: 10.1016/j.anorl.2025.02.004

Y Lelonge, A Havasi, N Williet, B Le Roy

{"title":"Acute intestinal obstruction due to duodenal metastasis of laryngeal squamous cell carcinoma: A CARE case report.","authors":"Y Lelonge, A Havasi, N Williet, B Le Roy","doi":"10.1016/j.anorl.2025.02.004","DOIUrl":"https://doi.org/10.1016/j.anorl.2025.02.004","url":null,"abstract":"<p><strong>Objective: </strong>To report a case of duodenal metastasis of laryngeal squamous cell carcinoma revealed by acute intestinal obstruction.</p><p><strong>Case report: </strong>A 55-year-old male was initially treated for cT4N1M0 laryngeal squamous cell carcinoma, with total laryngectomy, bilateral neck dissection, total thyroidectomy and pectoralis major flap. Subsequently, he received radiotherapy and chemotherapy. Then, he was periodically monitored, with clinical examination and cervicothoracic CT, according to guidelines. Three years later, he presented acute intestinal obstruction. Abdominal CT revealed a 35mm obstructive duodenal tumor involving the head of the pancreas. Gastroscopy enabled biopsies, which confirmed metastasis of the laryngeal carcinoma. After gastro-entero-anastomosis, a first line treatment with cisplatin, 5-fluorouracile and pembrozilumab was started. It was complicated by abdominal bleeding, which required inferior duodenopancreatic artery embolization and colic perforation requiring colectomy. Due to deterioration in general health, 2 injections of pembrozilumab alone were made. Then, because of progression, the patient received 1 second-line injection of docetaxel. He finally died of acute pancreatitis, 7 months after diagnosis.</p><p><strong>Conclusion: </strong>Duodenal metastasis of squamous cell carcinoma of the larynx is rare but possible. This case report highlights the importance of clinical and radiological monitoring, particularly in locally advanced tumor.</p>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Audiometry results in adult cochlear implant patients according to the electrode array.

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-07 DOI: 10.1016/j.anorl.2025.02.005

F Micaletti, M Marx, L Pelle-Bouleau, N Alfaqan, J J Galvin, D Bakhos

{"title":"Audiometry results in adult cochlear implant patients according to the electrode array.","authors":"F Micaletti, M Marx, L Pelle-Bouleau, N Alfaqan, J J Galvin, D Bakhos","doi":"10.1016/j.anorl.2025.02.005","DOIUrl":"https://doi.org/10.1016/j.anorl.2025.02.005","url":null,"abstract":"<p><strong>Objective: </strong>To assess audiological outcome in adult (>18years) cochlear implant (CI) users with a straight (SA) or perimodiolar electrode array (PMA).</p><p><strong>Material and methods: </strong>Between 2017 and 2021, medical records of patients in 2 French centers who received a Cochlear™ SA (CI522/CI622) or PMA (CI532/CI632) CI were retrospectively analyzed according to the STROBE guidelines. Air-conduction pure-tone audiometry and disyllabic speech audiometry were recorded over a minimum 3-year follow-up. Only patients with thresholds above 90dB at low frequencies (500Hz) before surgery were considered to have residual hearing (RH). Surgery-related complications (e.g., vertigo, peripheral facial palsy, meningitis) were assessed. The significance threshold was set at P<0.005.</p><p><strong>Results: </strong>We included 185 adult patients: 94 SA and 91 PMA. Median age at CI was 64.5±11.5years for SA and 60.9±12.2years for PMA. Preoperative unaided pure-tone averages (PTA) were comparable between SA and PMA (100 and 102dB, respectively; P=0.32), as were postoperative aided free-field air-conduction PTAs at 3months (30.9±6.0 and 31.3±8.8dB, respectively; P=0.68). Percentage correct dissyllabic word responses at 60dB HL did not significantly differ between SA and PMA before CI (P=0.483), or 1year (P=0.775), 2years (P=0.441) or 3years (P=0.785) post-CI, although there was a significant difference at 3months post-CI (P=0.001) in favor of PMA. Fifty-one patients (21 SA, 30 PMA) had RH prior to surgery; after 12months' CI experience, 14.2% of these had RH in the SA group and 13.3% in the PMA group. One peripheral facial palsy occurred in the SA group but resolved completely (P>0.99). Twenty patients experienced transient postoperative vertigo (10 SA [10.6%], 10 PMA [10.9%]; P=0.93). No meningitis was noted.</p><p><strong>Conclusion: </strong>CI with straight or perimodiolar electrodes provided similar improvement in audiological performance.</p>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of epistaxis in Osler-Weber-Rendu disease by bevacizumab nasal spray. The EROSB study: Determining the effective dose 贝伐珠单抗鼻喷雾剂治疗奥斯勒-韦伯-伦杜病鼻衄。EROSB研究：确定有效剂量。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.10.006

L. Vincent , L. Robard , C. Creveuil , E. Babin , M. Perreard , M. Humbert

{"title":"Treatment of epistaxis in Osler-Weber-Rendu disease by bevacizumab nasal spray. The EROSB study: Determining the effective dose","authors":"L. Vincent , L. Robard , C. Creveuil , E. Babin , M. Perreard , M. Humbert","doi":"10.1016/j.anorl.2024.10.006","DOIUrl":"10.1016/j.anorl.2024.10.006","url":null,"abstract":"<div><div>Treatment of nosebleeds in Osler-Weber-Rendu disease (OWRD) is a therapeutic challenge. Intranasal anti-angiogenic sprays are a promising solution, requiring scientific validation, leading us to conduct the present study.</div></div><div><h3>Objective</h3><div>The main objective was to determine the minimum effective dose of bevacizumab by intranasal spray to treat epistaxis in OWRD: i.e., the dose resulting in≥50% reduction in the number of nosebleeds at 1 month of treatment compared to the month prior to inclusion for 60% of patients. The secondary objectives were to assess treatment efficacy at 3 and 6 months and progression in the number and impact of nosebleeds, and to document pharmacokinetics.</div></div><div><h3>Materials and methods</h3><div>The study, named EROSB (treatment of epistaxis in patients with OWRD using a bevacizumab intranasal spray), under the French Hospitals Clinical Research Program (PHRC-I 2013), was selected by the Inter-regional Clinical Research and Innovation Group (GIRCI). It was a phase I/II prospective single-blind study based on 10 cohorts of 3 patients each, using the Continual Reassessment Method (CRM) to determine the minimum effective dose of bevacizumab.</div></div><div><h3>Results</h3><div>Due to difficulties in recruiting enough patients, the study was stopped after inclusion of 15 subjects. The CRM method identified 64mg as the minimum effective dose. However, this result is not interpretable due to the small number of subjects.</div></div><div><h3>Conclusion</h3><div>The EROSB study did not succeed in identifying a minimum effective dose of bevacizumab, administered as intranasal spray that could reduce the number of nosebleeds compared to the month prior to inclusion. However, the initial results indicated almost no systemic passage of the substance.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 2","pages":"Pages 67-73"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relevance of anatomical remnants for revision sinus surgery 解剖残留物与鼻窦翻修手术的相关性。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.09.009

D. Martin-Jimenez , R. Moreno-Luna , C. Gago-Torres , J. Maza-Solano , S. Sanchez-Gomez

{"title":"Relevance of anatomical remnants for revision sinus surgery","authors":"D. Martin-Jimenez , R. Moreno-Luna , C. Gago-Torres , J. Maza-Solano , S. Sanchez-Gomez","doi":"10.1016/j.anorl.2024.09.009","DOIUrl":"10.1016/j.anorl.2024.09.009","url":null,"abstract":"<div><h3>Objectives</h3><div>Review of the scientific literature dedicated to investigating how residual structures impact surgical outcomes in chronic rhinosinusitis (CRS) patients, providing information on the frequency of anatomical remnants after endoscopic sinus surgery (ESS).</div></div><div><h3>Material and methods</h3><div>This review has been reported following the recommendations of the SWiM guideline. PubMed, Cochrane Library, Embase, and Web of Science were searched until April 2024. Studies selected for the systematic review were assessed about quality and risk of bias using the Oxford Centre for Evidence-Based Medicine Levels of Evidence and STROBE. The findings were analyzed descriptively and qualitatively, aligning with EPOS and ICAR guidelines.</div></div><div><h3>Results</h3><div>Fourteen relevant studies met the inclusion criteria for qualitative synthesis. Prospective and retrospective cross-sectional designs, focusing on revision ESS, were included. Four studies examined full-house functional ESS (FESS), three focused on frontal sinus surgery, four on conventional FESS and three did not specify the surgery type. The risk of bias was assessed, revealing significant variability in study quality and a low level of evidence. Wide variability was found in anatomical structures remaining after ESS, most notably in retained uncinate process (29.6–64%), agger nasi cell (4.5–83.33%) and frontoethmoidal cells (40.7–96.8%). Observations on concha bullosa, septal deviation and lateralization of the middle turbinate revealed distinct patterns among the included studies.</div></div><div><h3>Conclusion</h3><div>This systematic review underscores the persistent challenge of incomplete resection of anatomical structures in revision surgeries for CRS. The variability in the retention of key structures highlights the complexity of surgical outcomes and the need for further refinement in surgical techniques.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 2","pages":"Pages 84-92"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laryngotracheal mucormycosis in children: Therapeutic challenges 儿童喉气管粘液瘤病：治疗难题。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.10.005

É. Moreddu , M. Dallemagne , D. Rousseau , F. Blanc

引用次数: 0

External auditory canal chondroid syringoma with bone erosion: A CARE case report 外耳道软骨样鼓膜瘤伴骨侵蚀：一例CARE报告。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.11.004

J. Connesson, C. Beck, C. Vincent, P. Toulemonde

引用次数: 0

Environmental impact of pediatric ENT surgery: A STROBE analysis 儿童耳鼻喉外科手术的环境影响：一个频闪分析。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.11.005

M. Martin , S. Ayraud-Thevenot , X. Dufour , J.-P. Lebreton , J. Guihenneuc , F. Carsuzaa

{"title":"Environmental impact of pediatric ENT surgery: A STROBE analysis","authors":"M. Martin , S. Ayraud-Thevenot , X. Dufour , J.-P. Lebreton , J. Guihenneuc , F. Carsuzaa","doi":"10.1016/j.anorl.2024.11.005","DOIUrl":"10.1016/j.anorl.2024.11.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Increasing emissions of greenhouse gases contribute to climate change. The healthcare sector, and particularly the operating room, is a significant emitter of greenhouse gases. In head-and-neck surgery, pediatric procedures are very common, but few studies have assessed their ecological impact. Our objective was to quantify the carbon footprint of common pediatric head-and-neck surgeries (tonsillectomy, adenoidectomy, and transtympanic tube placement).</div></div><div><h3>Methods</h3><div>An eco-epidemiological study was conducted in December 2022 in a tertiary hospital center. The carbon footprint of 10 pediatric head-and-neck surgeries (tonsillectomies, adenoidectomies, transtympanic tube placements) was calculated, as the sum of carbon dioxide (CO<sub>2</sub>eq) emissions generated by patient and medical staff transport, waste production, energy consumption in operating rooms, manufacturing and transport of disposable and reusable medical devices (MDs), medication production, and sterilization of reusable MDs.</div></div><div><h3>Results</h3><div>The carbon footprint of 1 pediatric head-and-neck surgery was 57.86kgCO<sub>2</sub>eq. Disposable MDs were the most polluting item with 30.82kgCO<sub>2</sub>eq (53.3%). Patient transport accounted for 27.4%, medication for 12.6% and reusable MDs for 2.9%.</div></div><div><h3>Conclusions</h3><div>Pediatric head-and-neck surgeries generate a significant quantity of CO<sub>2</sub>, mostly due to the production and delivery of disposable MDs. These observations could serve as a starting point for ecological actions consistent with an environmentally sustainable and climate-resilient health system.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 2","pages":"Pages 74-78"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A century ago, W.E. Sistrunk described a surgical technique still relevant today 一个世纪前，西斯特伦克（W.E. Sistrunk）描述了一种今天仍然适用的外科技术。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.12.002

C.A. Righini , C. Fabre

引用次数: 0

Evaluation of bone-conducted oVEMPs using frontal medial and mastoid stimulations 使用额内侧和乳突刺激评估骨传导的 oVEMPs。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.09.010

S. Ghavami , M. Kayal , R. Maire

{"title":"Evaluation of bone-conducted oVEMPs using frontal medial and mastoid stimulations","authors":"S. Ghavami , M. Kayal , R. Maire","doi":"10.1016/j.anorl.2024.09.010","DOIUrl":"10.1016/j.anorl.2024.09.010","url":null,"abstract":"<div><h3>Aims</h3><div>To determine the optimal stimulation intensity for frontal stimulation with a modified slit lamp holder and to compare the reliability and symmetry of bone-conducted ocular vestibular evoked myogenic potentials (oVEMPs) using two stimulation sites: frontal medial and mastoid.</div></div><div><h3>Methods</h3><div>This observational study included 33 healthy volunteers (15 women, 18 men; mean age 24.5years) at the University Hospital of Lausanne. Participants underwent otoneurological assessments, and those with normal results were included. Bone-conducted oVEMPs were recorded using a Brüel and Kjaer mini-shaker type 4810. A modified slit lamp holder was used for frontal stimulation to ensure consistent application pressure, freeing the examiner's hands. Mastoid stimulation was performed manually.</div></div><div><h3>Results</h3><div>The best reproducibility of oVEMP recordings was observed at 70dB nHL. Frontal stimulation demonstrated lower dispersion of data and lower asymmetry ratios of latencies (up to 7%) and amplitudes (up to 50%) compared to mastoid stimulation (up to 40% for latencies). Single stimulations at both frontal and mastoid sites were sufficient to obtain reliable measurements of both utricles.</div></div><div><h3>Conclusion</h3><div>Frontal stimulation at 70dB nHL using a modified slit lamp holder is recommended for bone-conducted oVEMP recordings due to its superior reproducibility, comfort, and reliability. This study establishes a new standard for optimal stimulation intensity and supports the use of frontal stimulation in clinical practice.</div></div>","PeriodicalId":48834,"journal":{"name":"European Annals of Otorhinolaryngology-Head and Neck Diseases","volume":"142 2","pages":"Pages 61-66"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving post-treatment follow-up of HPV-driven oropharyngeal cancers 改善由 HPV 引起的口咽癌的治疗后随访。

IF 1.9 4区医学

European Annals of Otorhinolaryngology-Head and Neck Diseases Pub Date : 2025-03-01 DOI: 10.1016/j.anorl.2024.04.003

H. Mirghani , P. Blanchard

引用次数: 0