Lancet PsychiatryPub Date : 2024-11-19DOI: 10.1016/s2215-0366(24)00331-6
Jan Dirk Blom, Brian A Sharpless
{"title":"On the perceptual characteristics of auditory verbal hallucinations","authors":"Jan Dirk Blom, Brian A Sharpless","doi":"10.1016/s2215-0366(24)00331-6","DOIUrl":"https://doi.org/10.1016/s2215-0366(24)00331-6","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"22 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142673002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lancet PsychiatryPub Date : 2024-11-19DOI: 10.1016/s2215-0366(24)00316-x
Claudia Buntrock, Mathias Harrer, Antonia A Sprenger, Susan Illing, Masatsugu Sakata, Toshi A Furukawa, David D Ebert, Pim Cuijpers
{"title":"Psychological interventions to prevent the onset of major depression in adults: a systematic review and individual participant data meta-analysis","authors":"Claudia Buntrock, Mathias Harrer, Antonia A Sprenger, Susan Illing, Masatsugu Sakata, Toshi A Furukawa, David D Ebert, Pim Cuijpers","doi":"10.1016/s2215-0366(24)00316-x","DOIUrl":"https://doi.org/10.1016/s2215-0366(24)00316-x","url":null,"abstract":"<h3>Background</h3>Psychological interventions are increasingly discussed as a method to prevent major depressive disorder (MDD) in adults who already experience subthreshold depressive symptoms. In this individual participant data meta-analysis, we quantify the effect of preventive interventions against control on MDD onset in this population, and explore effect modifiers.<h3>Methods</h3>In this systematic review and individual participant data meta-analysis, we screened full-texts of eligible studies within the Metapsy research domain for articles on psychological interventions for depression, from database inception to May 1, 2023, published in English, German, Spanish, and Dutch. We included individual participant data of randomised trials comparing psychological interventions with a control group regarding their effects on MDD onset in adults with subthreshold depressive symptoms but no MDD at baseline, confirmed by standardised diagnostic interviews. Risk of bias was assessed using the RoB 2 tool. Effect on the onset of MDD (the primary outcome) and moderators were analysed using one-stage individual participant data meta-analysis. Survival analyses were conducted to examine effects on time to MDD onset within 12 months. We involved people with related lived experience in the study design and implementation. This study is registered with PROSPERO, CRD42017058585.<h3>Findings</h3>30 of 42 eligible randomised controlled trials with 7201 participants (2227 [30·9%] male, 4957 [68·9%] female, and 17 [0·2%] preferred not to report their sex) were included in our analysis (3697 participants had intervention and 3504 participants had control). The mean age of participants was 49·9 years (SD 19·2). Of the 3152 participants with reported ethnicity, 1608 (51·0%) were White. Five studies received a high risk of bias rating. Psychological interventions were associated with significantly reduced MDD incidence at post-treatment (incidence rate ratio [IRR] 0·57 [95% CI 0·35–0·93]; τ<sup>2</sup>=0·29; 18 studies), within 6 months (0·58 [0·39–0·88]; τ<sup>2</sup>=0·11; 18 studies), and within 12 months (0·67 [0·51–0·88]; τ<sup>2</sup>=0·05; 19 studies). No significant effect was observed at 24 months (IRR 1·16 [95% CI 0·66–2·03]; τ<sup>2</sup>=0·10; six studies). Preventive effects were stronger for individuals who had not previously had psychotherapy (IRR 0·39 [95% CI 0·25–0·62]) compared with those who had received psychotherapy before (0·92 [0·61–1·36]; p=0·029; seven studies). Although no overall linear association was identified, higher baseline depressive (Patient Health Questionnaire-9) and anxiety symptom (Generalized Anxiety Disorder-7) scores were associated with greater reductions in MDD onset risk. On the study level, delivery type appeared to moderate outcomes, with conference telephone calls being more effective than delivery via face-to-face, internet-based, and other formats (p=0·002), albeit based on only two studies of conference telephone ","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"12 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142673008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lancet PsychiatryPub Date : 2024-11-19DOI: 10.1016/s2215-0366(24)00332-8
Martyn Pickersgill
{"title":"Re-engaging society: on the Darzi report and mental health in England","authors":"Martyn Pickersgill","doi":"10.1016/s2215-0366(24)00332-8","DOIUrl":"https://doi.org/10.1016/s2215-0366(24)00332-8","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"42 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142673005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lancet PsychiatryPub Date : 2024-11-19DOI: 10.1016/s2215-0366(24)00398-5
{"title":"Correction to Lancet Psychiatry 2024; 11: 1012–21","authors":"","doi":"10.1016/s2215-0366(24)00398-5","DOIUrl":"https://doi.org/10.1016/s2215-0366(24)00398-5","url":null,"abstract":"<em>Santomauro DF, Vos T, Whiteford HA, Chisholm D, Saxena S, Ferrari AJ. Service coverage for major depressive disorder: estimated rates of minimally adequate treatment for 204 countries and territories in 2021.</em> Lancet Psychiatry <em>2024;</em> 11: <em>1012–21</em>—In figures 1 and 3 of this Article, the colours for some locations have been updated and statements added to the legends regarding WHO standards for geographical delineations. In the appendix, the names of some locations have been updated. These corrections have been made to the online version as of Nov 19, 2024.","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"36 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142672993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lancet PsychiatryPub Date : 2024-11-19DOI: 10.1016/s2215-0366(24)00313-4
Robin M Murray, Andreas Heinz, Carsten Hjorthøj, Tony George, Marco Colizzi
{"title":"Challenges in addressing youth mental health","authors":"Robin M Murray, Andreas Heinz, Carsten Hjorthøj, Tony George, Marco Colizzi","doi":"10.1016/s2215-0366(24)00313-4","DOIUrl":"https://doi.org/10.1016/s2215-0366(24)00313-4","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"174 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142672998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lancet PsychiatryPub Date : 2024-11-19DOI: 10.1016/s2215-0366(24)00373-0
Sharon A S Neufeld
{"title":"Are global estimates of minimally adequate treatment for major depressive disorder based on minimally adequate data?","authors":"Sharon A S Neufeld","doi":"10.1016/s2215-0366(24)00373-0","DOIUrl":"https://doi.org/10.1016/s2215-0366(24)00373-0","url":null,"abstract":"No Abstract","PeriodicalId":48784,"journal":{"name":"Lancet Psychiatry","volume":"92 1","pages":""},"PeriodicalIF":64.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142672995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}