Applied Sciences-Basel最新文献

{"title":"Comparative Analysis of Cooling Methods for Dynamic Infrared Thermography (DIRT)-Based Skin Cancer Diagnosis","authors":"J. Verstockt, Filip Thiessen, I. Hoorens, L. Brochez, Gunther Steenackers","doi":"10.3390/app131810105","DOIUrl":"https://doi.org/10.3390/app131810105","url":null,"abstract":"Skin cancer is a significant global health issue, placing a growing burden on individuals and society. Conventional diagnostic methods like visual examination and biopsy have limitations in invasiveness and accuracy. As a result, alternative tools such as infrared thermography have gained attention in skin cancer diagnosis. Tissue-mimicking phantoms have been instrumental in facilitating research in this field, offering controlled environments. While they do not fully replicate human skin complexity, physical skin models provide stability, ease of fabrication, and control over properties. Agarose phantoms are employed in this study. This research focused on testing and comparing cooling techniques for human skin in the context of skin cancer diagnosis using dynamic infrared thermography. Six cooling methods were investigated: a cool pack, an aluminum medal, ice, alcohol, a vortex cooler and a Zimmer Cryo 6 cooler. The experimental setup involved an infrared camera (Optris Xi400) with microscope optics positioned above an agar phantom mimicking flat skin and an ulcerating skin lesion. Based on experiments conducted on the skin phantom, it was observed that convective cooling methods offered more consistent and uniform cooling. Conversely, conductive methods proved effective for flat objects but posed challenges in achieving uniform cooling for bulging skin or ulcerated lesions. Ice or alcohol were deemed unsuitable due to artifacts influencing the infrared radiation and thermal camera view. A decision matrix assessed cooling techniques based on criteria such as uniformity, repeatability, view obstruction, efficiency, workload, patient comfort, clinical suitability, noise exposure, consumables, additional equipment, and price. The Zimmer Cryo 6 cooler emerged as the most suitable cooling method after evaluating various factors.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44282817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a 3-DOF Cylindrical Ultrasonic Motor Based on Non-Standard Modes","authors":"Jingwen Leng, Long Jin, Zhike Xu, X. Zhu","doi":"10.3390/app131810096","DOIUrl":"https://doi.org/10.3390/app131810096","url":null,"abstract":"Cylindrical multi-degree-of-freedom (multi-DOF) ultrasonic motors have the potential to significantly reduce motor size compared to other ultrasonic motors. They find applications in various systems, including micro-robot joints and space probes. This paper proposes a 3-DOF cylindrical ultrasonic motor with hybrid vibration modes. Hybrid vibration modes encompass non-standard longitudinal and bending vibrations. The structure and operating principle of the motor are described first. COMSOL Multiphysics models the stator’s vibration modes, frequency response, and 3-DOF motion. A motor prototype is manufactured and characterized to demonstrate the output characteristics of the motor. The results indicate that the motor has a no-load speed of 37 rpm along the x- and y-axes and up to 77 rpm along the z-axis. The maximum output torque of the motor is 25 Nm. The motor is low in height and compact, providing a method for further reducing the stator length of motors of the same type.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45570182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volumetric Modulated Arc Therapy for Radiosurgery of Brain Metastases: A Single-Center Study","authors":"J. M. Sánchez-Villalobos, A. Serna-Berna, J. Salinas-Ramos, P. Escolar-Pérez, Marina Andreu-Gálvez, Emma Martínez-Alonso, J. Pérez-Vicente, Miguel Alcaraz","doi":"10.3390/app131810097","DOIUrl":"https://doi.org/10.3390/app131810097","url":null,"abstract":"Whole-brain radiation therapy and stereotactic radiosurgery are two treatment modalities commonly utilized to treat brain metastases (BMs). The aim of this study is to retrospectively analyze the main radio-oncologic and clinical-demographic aspects of a cohort of BM patients treated with Volumetric Modulated Arc Therapy for radiosurgery (VMAT-RS). This is a cross-sectional observational design study with a retrospective review of the medical records of patients with brain metastases treated with VMAT-RS between 2012 and 2018. Clinical and demographic data, with special attention to sex, age, primary tumor, brain tumor-related epilepsy (BTRE), number and brain location of BMs, Karnofsky Performance Status (KPS), the updated DS-GPA prognostic index, and the survival estimated according to the Kaplan–Meier model from the date of radiosurgery, were analyzed. One hundred and twenty-one patients with 229 BMs were treated with VMAT-RS. Patients presented 1–4 BMs, which were treated with five non-coplanar VMAT arcs. Sixty-eight percent of the patients had lung cancer, and 35% of the BMs were in the frontal lobe. The proportion of local control was 88.5%. BTRE prevalence was 30.6%. The median survival time (MST) was 7.7 months. In the multivariate analysis of the Cox regression model, KPS ≥ 70 (HRKPS < 70 = 2.59; p = 0.001) and higher DS-GPA (HRDS-GPAII = 0.55, p = 0.022; HRDS-GPAIII-IV = 0.38, p = 0.006) were associated with improved survival. In the univariate analysis, primary tumor, age, and the presence of metastases in the posterior fossa (PFBMs) were also significant. In conclusion, the VMAT-RS is a technique with an overall survival rate comparable to other radiosurgery techniques. The median survival is significantly longer for those with higher KPS and DS-GPA. Other variables, such as the type of primary tumor, age, and PFBMs, could also influence survival, although further studies are needed.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46522448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tissue Response to a Heat Resistant Silicate-Based and an Epoxy Resin-Based Endodontic Sealer Implanted in Rat Tibias","authors":"O. Zmener, C. Pameijer, Roberto Della Porta, Romina de Lucca","doi":"10.3390/app131810075","DOIUrl":"https://doi.org/10.3390/app131810075","url":null,"abstract":"Introduction: The effect of high temperatures on the properties of endodontic sealers during warm compaction of gutta-percha may be a matter of concern. This study aimed to evaluate the effect of heat on the biocompatibility and bioactivity of EndoSequence BC Sealer HiFlow (ESHF; Brasseler, Savannah, GA, USA) and AH Plus (AHPS; Dentsply, De Trey, Konstanz, Germany) when implanted into the bone tissue of rat tibias. Methods: Medical-grade silicone tubes containing freshly prepared ESHF or AHPS were heated to 100 °C and then cooled down to 65 °C before being implanted in the tibias of 24 Wistar rats. The outer walls of the tubes served as controls. After 10, 30 and 90 days, the animals were euthanized and the implants and their surrounding tissues were dissected, fixed in formalin, and processed for microscopic evaluation. Results: After 10 days postoperatively, a severe inflammatory reaction without reactionary bone formation was observed in contact with ESHF and AHPS. The severity of the reaction had decreased at the 30-day observation period for both sealers but only ESHF samples showed new bone formation adjacent to the sealer. After 90 days, no inflammatory cells were found in contact with ESHF, while a thin fibrous tissue capsule and complete bone reparation of the surrounding areas were observed in contact with the material. For AH Plus, a fibrous connective tissue containing scarce remaining inflammatory cells could be observed in most of the samples, however, in the absence of new bone formation. No significant differences (p > 0.05) between ESHF and AHPS were found at the 10-day observation period. At the 30 and 90-day, significant differences (p < 0.05) between both materials were observed. The reaction to the controls showed significant differences with ESHF and AHPS for all experimental periods. Significant differences (p < 0.05) for the total effect of time were also found between both sealers (p < 0.05). Conclusions: At the end of the experiment, heated ESHF reacted as a biocompatible/bioactive material and stimulated continued development of new healthy bone. Although AHPS was tolerated well by the surrounding tissues, the sealer did not promote new reparative bone formation.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43396120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generation of a Virtual Cohort of Patients for in Silico Trials of Acute Ischemic Stroke Treatments","authors":"Sara Bridio, Giulia Luraghi, Anna Ramella, J. F. Rodriguez Matas, G. Dubini, Claudio A. Luisi, Michael Neidlin, P. Konduri, N. Arrarte Terreros, H. Marquering, C. Majoie, Francesco Migliavacca","doi":"10.3390/app131810074","DOIUrl":"https://doi.org/10.3390/app131810074","url":null,"abstract":"The development of in silico trials based on high-fidelity simulations of clinical procedures requires the availability of large cohorts of three-dimensional (3D) patient-specific anatomy models, which are often hard to collect due to limited availability and/or accessibility and imaging quality. Statistical shape modeling (SSM) allows one to identify the main modes of shape variation and to generate new samples based on the variability observed in a training dataset. In this work, a method for the automatic 3D reconstruction of vascular anatomies based on SSM is used for the generation of a virtual cohort of cerebrovascular models suitable for computational simulations, useful for in silico stroke trials. Starting from 88 cerebrovascular anatomies segmented from stroke patients’ images, an SSM algorithm was developed to generate a virtual population of 100 vascular anatomies, defined by centerlines and diameters. An acceptance criterion was defined based on geometric parameters, resulting in the acceptance of 83 generated anatomies. The 3D reconstruction method was validated by reconstructing a cerebrovascular phantom lumen and comparing the result with an STL geometry obtained from a computed tomography scan. In conclusion, the final 3D models of the generated anatomies show that the proposed methodology can produce a reliable cohort of cerebral arteries.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42187010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bayesian Network Demand-Forecasting Model Based on Modified Particle Swarm Optimization","authors":"Shebiao Hu, Kun Li","doi":"10.3390/app131810088","DOIUrl":"https://doi.org/10.3390/app131810088","url":null,"abstract":"With the increasing variety of products, the increasing substitutability of products, and the trend of customized products, the volatility of market demand is increasing, which poses a challenge to make accurate demand forecasting. The Bayesian method is particularly promising and appealing when the data fluctuate greatly. This paper proposes a product-demand forecasting model based on multilayer Bayesian network, which introduces hidden layer variables and volatility factors to meet the time series connection and volatility of the demand data. However, most studies use sampling methods to estimate the parameters. We use Bayesian maximum a posteriori estimation to estimate the model parameters and introduce an improved particle swarm optimization algorithm (MPSO) to optimize the objective function. In order to increase the diversity of the particle population and accelerate the convergence, an adaptive particle velocity, position updating strategy, and nonlinear changing inertia weight are introduced in the algorithm. Finally, RMSE (Root Mean Square Error) and MAPE (Mean Absolute Percentage Error) are used as the evaluation criterion to conduct experiments on six different datasets, and the experimental results are compared with the results of the ARIMA (autoregressive integrated moving average model) method and PSO algorithm. The experimental results show that the method has a good prediction effect. It provides a new idea for demand forecasting in the supply chain.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46010523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Special Issue on Optical Camera Communications and Applications","authors":"Pankaj Singh, Sung-Yoon Jung","doi":"10.3390/app131810091","DOIUrl":"https://doi.org/10.3390/app131810091","url":null,"abstract":"Optical Camera Communication (OCC) is a groundbreaking technology that combines optical signals and image sensors for data transmission [...]","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47082949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Identification Method of Feature Interpretation for Melanoma Using Machine Learning","authors":"Zhenwei Li, Qing Ji, Xiaoli Yang, Yu Zhou, Shulong Zhi","doi":"10.3390/app131810076","DOIUrl":"https://doi.org/10.3390/app131810076","url":null,"abstract":"Melanoma is a fatal skin cancer that can be treated efficiently with early detection. There is a pressing need for dependable computer-aided diagnosis (CAD) systems to address this concern effectively. In this work, a melanoma identification method with feature interpretation was designed. The method included preprocessing, feature extraction, feature ranking, and classification. Initially, image quality was improved through preprocessing and k-means segmentation was used to identify the lesion area. The texture, color, and shape features of this region were then extracted. These features were further refined through feature recursive elimination (RFE) to optimize them for the classifiers. The classifiers, including support vector machine (SVM) with four kernels, logistic regression (LR), and Gaussian naive Bayes (GaussianNB) were applied. Additionally, cross-validation and 100 randomized experiments were designed to guarantee the generalization of the model. The experiments generated explainable feature importance rankings, and importantly, the model demonstrated robust performance across diverse datasets.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48650007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on Conditions and Influence Factors of an Acoustic Wave Acting as a Plane Wave in Tire Acoustic Cavity","authors":"Xiaojun Hu, Xiandong Liu, Yingchun Shan, Tian He","doi":"10.3390/app131810078","DOIUrl":"https://doi.org/10.3390/app131810078","url":null,"abstract":"Tire acoustic cavity resonance noise (TACRN) contributes significantly to the interior noise of electric cars and passenger cars with lower powertrain noise, which affects the comfort of the ride. To suppress TACRN effectively, it is crucial to clarify the characteristics of TACRN. In previous studies, the acoustic wave in the tire acoustic cavity is straightforwardly assumed to be the plane wave for convenience. In fact, there exist strict conditions for the acoustic wave propagating in the pipeline to act as a plane wave. The aim of this paper is to make the characteristics and evolution of acoustic waves in tire acoustic cavities clear. To do so, a simplified model of the tire cavity is established, and the sound field distribution and the acoustic wave propagation characteristics in the tire cavity are analyzed based on the theory of acoustic waveguide. Then, the existence ranges of higher-order waves (non-plane waves), the conditions of an acoustic wave evolving into a plane wave, and the frequency range of a plane wave are investigated. Finally, the characteristics and evolution law of an acoustic wave in a tire acoustic cavity are obtained. The work in this paper may deepen the understanding of the characteristics and mechanism of acoustic waves in the tire cavity and be helpful and meaningful for analyzing and suppressing TACRN. Therefore, it is of practical significance to reduce TACRN transmitted to the vehicle and improve the sound quality inside the vehicle.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47228124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Trends and Progress in Corrosion Inhibitors and Electrochemical Evaluation","authors":"K. Bijapur, Vandana Molahalli, Apoorva Shetty, A. Toghan, Paola De Padova, G. Hegde","doi":"10.3390/app131810107","DOIUrl":"https://doi.org/10.3390/app131810107","url":null,"abstract":"Science and engineering research studies are currently concentrating on synthesizing, designing, producing, and consuming ecologically benign chemical species to replace harmful chemicals. This is due to the increasing demands of conservation knowledge and strict ecological regulations. Numerous environmentally friendly substitutes produced from natural resources, including biopolymers, plant extracts, chemical pharmaceuticals (drugs), and so on, are now frequently used as inhibitors to replace dangerous corrosion inhibitors. Many compounds have been extensively used. A range of methods, including physisorption, chemisorption, barrier protection, thin-film growth, and electrochemical procedures, will be used to provide corrosion resistance. The various kinds of corrosion inhibitors (CIs), the mechanisms underlying inhibition, and the evaluation procedures have all been covered in-depth. This review provides an overview of the relevant literature in which researchers and scientists used different types of CIs, the effect of CIs on metals, and information about designs and mechanisms used to minimize corrosion in a variety of equipment composed of alloys or metals, along with electrochemical evaluation studies. This review will provide scholars with fresh insights to advance the discipline.","PeriodicalId":48760,"journal":{"name":"Applied Sciences-Basel","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47377404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}