Sofya Sadilina, Franz J Strauss, Ronald E Jung, Tim Joda, Marc Balmer
{"title":"Use of optical see-through head-mounted display (OST-HMD) in dentistry: a scoping review.","authors":"Sofya Sadilina, Franz J Strauss, Ronald E Jung, Tim Joda, Marc Balmer","doi":"10.3290/j.ijcd.b5394865","DOIUrl":"10.3290/j.ijcd.b5394865","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the present scoping review was to identify the scientific evidence related to the utilization of optical see-through head-mounted display (OST-HMD) in dentistry, and to determine future research needs.</p><p><strong>Methods: </strong>The research question was formulated using the 'Population' (P), 'Concept' (Cpt), and 'Context' (Cxt) framework for scoping reviews. Existing literature was designated as P, OST-HMD as Cpt, and Dentistry as Cxt. An electronic search was conducted in PubMed, Embase, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL). Two authors independently screened titles and abstracts and performed the full-text analysis.</p><p><strong>Results: </strong>The search identified 286 titles after removing duplicates. Nine studies, involving 138 participants and 1760 performed tests, were included in the present scoping review. Seven of the articles were preclinical studies, one was a survey, and one was a clinical trial. The included articles covered various dental fields: three studies in orthodontics, two in oral surgery, two in conservative dentistry, one in general dentistry, and the remaining one in prosthodontics. Five articles focused on educational purposes. Two brands of OST-HMD devices were used: in eight studies Microsoft HoloLens was used, while Google Glass was utilized in one study.</p><p><strong>Conclusions: </strong>The overall number of included studies was low; therefore, the available data from the present review cannot yet support an evidence-based recommendation for the clinical use of OST-HMD. However, the existing preclinical data indicate a significant capacity for clinical and educational implementation. Further adoption of OST-HMD devices will facilitate more reliable and objective quality and performance assessments as well as more direct comparisons with conventional workflows. More clinical studies must be conducted to substantiate the potential benefits and reliability for patients and clinicians.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"101-116"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Color change of laminate veneer restorations applied to bleached teeth.","authors":"Buse Atak Ay, Şebnem Begüm Türker","doi":"10.3290/j.ijcd.b5117207","DOIUrl":"10.3290/j.ijcd.b5117207","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the present study was to examine the color stability of laminate veneer restorations fabricated with various CAD/CAM materials applied to bleached teeth.</p><p><strong>Materials and methods: </strong>Eighty maxillary central incisors extracted due to periodontal, orthodontic, or trauma problems were used. The teeth were embedded in acrylic blocks and divided into eight groups (n = 10). Groups A, B, C, and D were bleached with a vital bleaching agent before preparation, and the teeth were prepared for laminate veneer restorations. Groups E, F, G, and H were prepared without bleaching. Groups A and E were restored with GC Initial LiSi HT Blocks A1, Groups B and F with GC Initial LiSi LT Blocks A1, Groups C and G with IPS e.max CAD HT Blocks A1, and Groups D and H with IPS e.max CAD LT Blocks A1. All restorations were adhesively cemented and aged for 2 and 5 years with thermal cycling. Color measurements of the restorations were taken with a spectrophotometer at baseline and after 2 and 5 years of aging.</p><p><strong>Results: </strong>Teeth in all the bleached groups showed more color changes than those in the unbleached groups. After 2 years of aging, the least color change was observed with GC Initial LiSi LT (ΔE00 = 0.808) and IPS e.max CAD LT (ΔE00 = 0.813) materials, which were used on unbleached teeth, and the most color change was observed with GC Initial LiSi HT (ΔE00 = 0.934) and IPS e.max CAD HT (ΔE00 = 0.923) materials, which were used on bleached teeth. After 5 years of aging, the least color change was observed with IPS e.max CAD LT (ΔE00 = 0.831) and GC Initial LiSi LT (ΔE00 = 0.839) materials, which were used on unbleached teeth, and the most color change was observed with GC Initial LiSi HT (ΔE00 = 0.957) and IPS e.max CAD HT (ΔE00 = 0.938) materials, which were used on bleached teeth.</p><p><strong>Conclusions: </strong>Bleaching and translucency affect color stability. No difference was detected between the color changes of GC Initial LiSi and IPS e.max CAD materials. The increase in aging time increased the color changes of all materials.</p><p><strong>Clinical significance: </strong>Bleaching and laminate veneer restorations may be preferred in many patients. For this reason, the long-term color changes of laminate veneer restorations applied to bleached teeth is clinically very relevant. The present study aimed to evaluate the effect of tooth bleaching on the long-term color stability of laminate veneer restorations fabricated with various CAD/CAM materials of different translucencies.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"141-149"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140185987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobias Graf, Tuba Aini, Michael Stimmelmayr, Silvia Brandt, Jan-Frederik Güth
{"title":"Digital implant prosthetics: patient-individual PEEK healing abutments - a case report.","authors":"Tobias Graf, Tuba Aini, Michael Stimmelmayr, Silvia Brandt, Jan-Frederik Güth","doi":"10.3290/j.ijcd.b6262983","DOIUrl":"https://doi.org/10.3290/j.ijcd.b6262983","url":null,"abstract":"<p><strong>Background: </strong>Implantology is becoming increasingly digital, opening up new therapy options to achieve preferably predictable and complication-free results. One key parameter for success seems to be stable and fixed soft tissue around the implant as well as the prosthodontic supply. The concept presented in this article aims for an anatoform and stable emergence profile around implants in a digital workflow applying individual polyetheretherketone (PEEK) healing abutments.</p><p><strong>Case presentation: </strong>A 63-year-old female patient presented to the Department of Prosthodontics at the Center for Dentistry and Oral Health of the Goethe University Frankfurt with implants inserted at regions 45 and 47 and conventional titanium healing abutments. An intraoral scan was performed and a screw-retained 3-unit fixed dental prosthesis (FDP) was designed. On the basis of the CAD, individual healing abutments were designed and fabricated out of PEEK, representing a similar emergence profile to that of the final FDP. The components were fabricated in a milling center and finalized. After soft tissue relocation, the individual PEEK healing abutments were placed. Then, after a 3-week rest period, a screw-retained FDP fabricated out of monolithic zirconium oxide was inserted without further soft tissue compression.</p><p><strong>Conclusion: </strong>Individual healing abutments fabricated out of PEEK might be an interesting therapy option for shaping the soft tissue around implants and can be supplemented as a straightforward tool especially in fully digital workflows.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"28 2","pages":"163-177"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathalie Robert, Eric Bechet, Adelin Albert, Marc Lamy
{"title":"Influence of the scanning path on the accuracy of intraoral scanners in the implanted edentulous patient: an in vitro study.","authors":"Nathalie Robert, Eric Bechet, Adelin Albert, Marc Lamy","doi":"10.3290/j.ijcd.b5036725","DOIUrl":"10.3290/j.ijcd.b5036725","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the present in vitro study was to investigate the influence of scan paths on the accuracy (trueness and precision) of intraoral scanning of an implant impression on an edentulous patient.</p><p><strong>Materials and methods: </strong>An epoxy resin maxillary cast was made with six bone level implants (NobelParallel Conical Connection RP). The implants were placed at the sites of the central incisors, canines, and first molars. The transgingival component (multi-unit) was screwed onto the implants. The scanbodies (Elos Accurate IO 2C-A) were then screwed onto the multi-units. The cast was run through a coordinate measurement machine to obtain a control model. Then, five different scanning paths were applied by a single operator: the zigzag technique (ZZT); the zigzag technique with palatal (ZZTP); the wrap technique (WT); the wrap technique with palatal (WTP); and the big zigzag technique (BZZT). Finally, each scan was compared with the control model. Results were assessed by one-way ANOVA and linear mixed effects models with a significance level of P 0.05.</p><p><strong>Results: </strong>The results showed that scan paths ZZT and ZZTP had significantly lower absolute positioning errors and root mean square errors than the other techniques (P 0.0001). For distances between consecutive implant axes and for absolute vertical errors, their superiority was borderline (P 0.10). Overall, techniques ZZT and ZZTP were equally performant and proved to be the most accurate scan paths.</p><p><strong>Conclusions: </strong>The present in vitro experimental study demonstrates that the scan path can have an influence on the accuracy of the optical impression for full-arch rehabilitations on implants.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"117-127"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139997944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dina Mohamed Elawady, Mohamed Denewar, Ahmed Yaseen Alqutaibi, Wafaa Ibrahim Ibrahim
{"title":"Clinical assessment of maxillary screw-retained implant prostheses fabricated from digital versus conventional full-arch implant impressions. A randomized controlled clinical trial.","authors":"Dina Mohamed Elawady, Mohamed Denewar, Ahmed Yaseen Alqutaibi, Wafaa Ibrahim Ibrahim","doi":"10.3290/j.ijcd.b5117247","DOIUrl":"10.3290/j.ijcd.b5117247","url":null,"abstract":"<p><strong>Aim: </strong>The objective of the present study was to evaluate the peri-implant marginal bone loss (MBL) and prosthodontic complications of maxillary screw-retained implant prostheses fabricated from digital versus conventional full-arch implant impressions.</p><p><strong>Materials and methods: </strong>Twenty-eight participants with edentulous maxillary arches were randomly selected and enrolled in two equal groups: Group I (conventional impression group, CIG); Group II (digital impression group, DIG). All patients were rehabilitated with a maxillary screw-retained implant prosthesis retained by six implants. Peri-implant MBL and prosthodontic complications were recorded at 6, 12, and 24 months. Data were collected and statistically analyzed.</p><p><strong>Results: </strong>Regarding the effect of time, there was a statistically significant increase in MBL at the 6-, 12-, and 24-month follow-ups (P 0.001). Regarding the effect of groups, there was no statistically significant difference in MBL between CIG and DIG at 6, 12, and 24 months, where P = 0.083, 0.087, and 0.133, respectively. Prosthetic complications were recorded 19 times in CIG and 12 times in DIG, with no significant difference between the groups (P = 0.303).</p><p><strong>Conclusion: </strong>Digital full-arch implant impression is a reliable impression technique and may represent an alternative to conventional implant impression technique in the fabrication of maxillary screw-retained implant prostheses.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"151-161"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140185986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ozden Melis Durmaz Yilmaz, Murat Tasyurek, Hasan Onder Gumus
{"title":"Evaluation of different color measurement methods for determining tooth color.","authors":"Ozden Melis Durmaz Yilmaz, Murat Tasyurek, Hasan Onder Gumus","doi":"10.3290/j.ijcd.b5290621","DOIUrl":"10.3290/j.ijcd.b5290621","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of the present study was to develop low-cost software that enables the detection of tooth colors by capturing photographs using various devices and to compare the effectiveness with existing expensive methods.</p><p><strong>Materials and methods: </strong>A total of 60 maxillary central incisors from 30 individuals were included in the study. The CIELAB values (L*, a*, b*) of each tooth were measured using a spectrophotometer, which is considered the gold standard. Subsequently, photographs of the teeth were taken using four different smartphones (iPhone and Xiaomi brands) and one digital camera (Canon EOS 70D DSLR). These images were then subjected to image processing techniques and compared with measurements obtained through computer-based analysis to assess the correlation. The Kruskal-Wallis H test was used (for data in three or more groups), and multiple comparisons were conducted using the Dunn test. The significance level was set at P 0.05.</p><p><strong>Results: </strong>On examining the results of multiple comparisons, a statistically significant difference was observed (P 0.001) between the Delta E (ΔE) values obtained from the iPhone cameras and those obtained from the Canon and Xiaomi cameras. The iPhone cameras yielded ΔE result values ranging from 2.68 to 2.90.</p><p><strong>Conclusions: </strong>Color determination methods based on the image processing of photographs taken with iPhone cameras could potentially gain an advantageous position in routine clinical practice as compared with spectrophotometry.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"129-139"},"PeriodicalIF":1.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Çopun, Bengü Doğu Kaya, Pınar Yılmaz Atalı, Erkut Kahramanoglu
{"title":"Effect of Thermal Aging on Glass Matrix Ceramic and Resin Matrix Ceramic CAD/CAM Blocks: Flexural Strength and Vicker's Microhardness Assessment.","authors":"Mustafa Çopun, Bengü Doğu Kaya, Pınar Yılmaz Atalı, Erkut Kahramanoglu","doi":"10.3290/j.ijcd.b6329245","DOIUrl":"https://doi.org/10.3290/j.ijcd.b6329245","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate and compare the flexural strength, elastic modulus, and Vicker's microhardness values of glass matrix ceramic and resin matrix ceramic CAD/CAM blocks, and to examine the differences after thermal aging.</p><p><strong>Methods: </strong>This in vitro study involved seven different CAD/CAM blocks: Amber Mill (Hassbio, Korea), LiSi (GC, Japan), Celtra Duo (Dentsply Sirona, Germany), Tessera (Dentsply Sirona, Germany), IPS e.max CAD (Ivoclar, Liechtenstein), Cerasmart (GC, Japan), and Grandio Blocs (VOCO, Germany). Bar-shaped samples (1.2x4x14mm) for the three-point bending test and rectangular samples (2mm-thickness) for the Vicker's microhardness test were prepared using a precision cutting device under water. Half of the samples underwent 50,000 thermal cycles between 5-55°C, while the other half were kept in distilled water at 37°C for 24 hours. Flexural strength/FS and elastic modulus/EM values were measured using a universal testing machine, and Vicker's microhardness/VHN values were measured using a microhardness tester. Statistical analyses were performed using Kruskal-Wallis and Mann- Whitney U tests, with significance set at p<0.05.</p><p><strong>Results: </strong>Tessera showed the highest median values for FS (570 MPa), EM (66.2 GPa), and VHN (717.7) after 24 hours, whereas Cerasmart had the lowest values (FS: 260 MPa; EM: 12.8 GPa; VHN: 99.9). Significant differences were found between the materials' FS, EM, and VHN values after 24 hours and after thermal aging (p<0.001). All materials showed a significant decrease in FS values following thermal aging (p<0.05).</p><p><strong>Conclusion: </strong>In the selection of CAD/CAM materials, it is critical to consider that mechanical properties vary with structure and tend to change over time due to aging.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"0"},"PeriodicalIF":1.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacio Pedrinaci, Anita Nasseri, Javier Calatrava, Emilio Couso-Queiruga, William V Giannobile, German O Gallucci, Mariano Sanz
{"title":"Accuracy and Efficiency of Artificial Intelligence and Manual Virtual Segmentation for Generation of 3D Printed Tooth Replicas.","authors":"Ignacio Pedrinaci, Anita Nasseri, Javier Calatrava, Emilio Couso-Queiruga, William V Giannobile, German O Gallucci, Mariano Sanz","doi":"10.3290/j.ijcd.b6329209","DOIUrl":"https://doi.org/10.3290/j.ijcd.b6329209","url":null,"abstract":"<p><strong>Aims: </strong>The primary aim of this in vitro study was to compare methods for generating 3D-printed replicas through virtual segmentation, utilizing artificial intelligence (AI) or manual processes, by assessing accuracy in terms of volumetric and linear discrepancies. The secondary aims were the assessment of time efficiency with both segmentation methods, and the effect of post-processing on 3D-printed replicas.</p><p><strong>Methods: </strong>Thirty teeth were scanned through Cone Beam Computed Tomography (CBCT), capturing the region of interest from human subjects. DICOM files underwent virtual segmentation through both AI and manual methods. Replicas were fabricated with a stereolithography 3D printer. After surface scanning of pre-processed replicas and extracted teeth, STL files were superimposed to compare linear and volumetric differences using the extracted teeth as the reference. Post-processed replicas were scanned to assess the effect of post-processing on linear and volumetric changes.</p><p><strong>Results: </strong>AI-driven segmentation resulted in statistically significant mean linear and volumetric differences of -0.709mm (SD 0.491, P< 0.001) and -4.70%, respectively. Manual segmentation showed no statistically significant differences in mean linear, -0.463mm (SD 0.335, P<0.001) and volumetric (-1.20%) measures. Comparing manual and AI-driven segmentations, AI-driven segmentation displayed mean linear and volumetric differences of -0.329mm (SD 0.566, p=0.003) and -2.23%, respectively. Additionally, AI segmentation reduced the mean time by 21.8 minutes. When comparing post-processed to pre-processed replicas, there was a volumetric reduction of -4.53% and a mean linear difference of -0.151mm (SD 0.564, p=0.042).</p><p><strong>Conclusion: </strong>Both segmentation methods achieved acceptable accuracy, with manual segmentation slightly more accurate but AI-driven segmentation more time-efficient. Continuous improvement in AI offers the potential for increased accuracy, efficiency, and broader application in the future.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"0"},"PeriodicalIF":1.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dynamic Navigation System Accuracy in Orthodontic Miniscrew Insertion in the Palatine Vault: A Prospective Single- Arm Clinical Study.","authors":"Davide Brilli, Matteo Giansanti, Serena Bertoldo, Isabella Cauli, Michele Cassetta","doi":"10.3290/j.ijcd.b6329377","DOIUrl":"https://doi.org/10.3290/j.ijcd.b6329377","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to evaluate the accuracy of Dynamic Navigation (DN) in miniscrew insertion in the palatine vault by comparing the deviation between planned and placed miniscrew positions. The secondary outcome was to evaluate the correlation between the number of miniscrews inserted and both the accuracy variables and the duration of interventions.</p><p><strong>Materials and methods: </strong>Twenty-three subjects were included in the study and each had 2 miniscrews inserted using a DN system (46 miniscrews inserted overall). Pre-operative STL and DICOM files were matched to planned miniscrews insertion and a post-operative CBCT was performed immediately afterwards to measure the deviations between the planned and placed miniscrews, evaluating four variables: Entry-3D, Apex-3D, Apex-vertical and angular deviation. The duration of intervention was also calculated. Descriptive statistics and Pearson correlation coefficient were performed; P-value was set at ≤ 0.05.</p><p><strong>Results: </strong>The mean Entry-3D deviation was 2.55 mm; the mean Apex-3D deviation was 3.11 mm; the mean Apex-point deviation was 0.87 mm; the mean angular deviation was 8.50°. The mean duration of the intervention was 2:75 min:sec. A statistically significant correlation was found only between the number of surgeries and the duration of the interventions, which decreased over time.</p><p><strong>Conclusion: </strong>It is possible to conclude that DN is a viable alternative to miniscrew insertion in the palatal vault even if there is a wide deviation range. There is no significant correlation between the accuracy variables and the number of surgeries. In contrast, the duration of the interventions shortens over time.</p>","PeriodicalId":48666,"journal":{"name":"International Journal of Computerized Dentistry","volume":"0 0","pages":"0"},"PeriodicalIF":1.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}