Internet Interventions-The Application of Information Technology in Mental and Behavioural Health最新文献

{"title":"Affect-focused psychodynamic psychotherapy for mothers diagnosed with cancer – A feasibility study","authors":"Astrid Kuylenstierna ,&nbsp;Maria Romare Strandh ,&nbsp;Greta Melzi ,&nbsp;Henrik Lindman ,&nbsp;Ylva Hellstadius ,&nbsp;Camilla Sköld ,&nbsp;Lisa Ljungman ,&nbsp;Anna Wikman","doi":"10.1016/j.invent.2026.100916","DOIUrl":"10.1016/j.invent.2026.100916","url":null,"abstract":"<div><h3>Background</h3><div>Parents with cancer face elevated psychological distress, often exacerbated by parenting responsibilities. Affect-Focused Psychodynamic Therapy (AFPT) has shown efficacy in improving emotion regulation, psychological well-being and self-compassion, but its feasibility and preliminary effect in this population remains unexplored.</div></div><div><h3>Objective</h3><div>The aim of this study was to evaluate the feasibility, acceptability, safety, and preliminary effects on symptoms of depression and anxiety, of AFPT delivered via videoconferencing for parents with cancer.</div></div><div><h3>Methods</h3><div>The intervention consisted of 10 sessions of AFPT, specifically affect phobia therapy. Qualitative data were collected through post-intervention interviews and analysed using inductive content analysis. Quantitative data were collected through self-report questionnaires at pre-intervention, post-intervention, and at 6-month follow-up measuring symptoms of depression and anxiety (primary outcome), parenting concerns, emotion regulation, self-efficacy, adaptive affective functioning, closeness in the family and self-rated health. Quantitative data were analysed using dependent-samples <em>t</em>-tests, with Cohen's <em>d</em> for effect sizes, and McNemar tests.</div></div><div><h3>Results</h3><div>Fifteen mothers with cancer participated in the study. Results demonstrated efficient recruitment, acceptable study procedures, complete retention, and a relevant and beneficial intervention rated 8.4/10 in helpfulness. Moreover, findings showed significant reductions in symptoms of depression (Cohen's <em>d</em> = 1.29) and of anxiety (Cohen's <em>d</em> = 1.06) from pre- to post-intervention, maintained at 6-month follow-up, together with improvements in a majority of the secondary outcomes.</div></div><div><h3>Conclusions</h3><div>Videoconferencing AFPT appears feasible, acceptable, and safe to use for mothers with cancer, with promising preliminary effects in reducing psychological distress. These findings support further evaluation of the intervention to determine its efficacy in this population using a randomized controlled trial.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"43 ","pages":"Article 100916"},"PeriodicalIF":4.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a guided internet-based intervention in reducing procrastination among university students – a randomized controlled trial","authors":"Arpana Amarnath ,&nbsp;Sevin Ozmen ,&nbsp;Chris van Klaveren ,&nbsp;Annemieke van Straten ,&nbsp;Julia Pei ,&nbsp;Leonore de Wit ,&nbsp;Rasmus E. Raabe ,&nbsp;Caring Universities Consortium ,&nbsp;Pim Cuijpers ,&nbsp;Sascha Y. Struijs","doi":"10.1016/j.invent.2025.100878","DOIUrl":"10.1016/j.invent.2025.100878","url":null,"abstract":"<div><div>Procrastination is highly prevalent among students and has several negative consequences, affecting academic performance, mental health, and prospects for future professional development. However, there exists a treatment gap, with there being many more students with problems than those receiving help. This study aims to assess the effectiveness of a guided internet-based intervention, <em>GetStarted</em>, in addressing procrastination among college students. In this two-arm randomized controlled trial, 403 students were randomly assigned to <em>GetStarted</em> or waitlist control. The primary outcome was the difference in self-reported procrastination behaviours between intervention and control measured on the Irrational Procrastination scale (IPS) at post-test (4 weeks post-baseline). In addition, long-term effects based on the difference in the IPS scores from baseline to 6-months follow-up were assessed in the intervention group. Secondary outcomes were differences in depressive symptoms, anxiety, stress, and mental health-related quality of life. All analyses were based on the intent to treat principle. The Random Forest Lee bounds approach was applied as a sensitivity and robustness analysis. The sociodemographic characteristics of the participants were examined as treatment moderators. Finally, treatment acceptability was assessed through satisfaction with treatment, program usability, satisfaction with e-coach, and treatment adherence. Our results revealed that <em>GetStarted</em> was significantly effective in reducing procrastination at the post-test (Cohen's <em>d =</em> 0.40), and this effect remained stable at 6-month follow-up (<em>p</em> &lt; .001). The intervention group also experienced reductions in depressive symptoms, anxiety, and stress, along with an increase in quality of life from baseline to post-test and 6-month follow-up, although these changes were not statistically significant apart from perceived stress. No significant moderators influenced treatment effectiveness. Overall, participants reported good acceptability of the treatment. <em>GetStarted</em> offers an effective, flexible, and low-intensity solution for treating procrastination, with the potential to prevent common mental health issues among college students.</div></div><div><h3>Trial registration</h3><div>This trial is registered at <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> Protocol Registration and Results System (Trial number: <span><span>NCT05478096</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100878"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevention of mental health issues in the young: A randomised controlled evaluation of an e-mental health application for young adults to enhance mental health literacy","authors":"Olivia Krokos ,&nbsp;Isabel Brandhorst ,&nbsp;Caterina Gawrilow ,&nbsp;Johanna Löchner","doi":"10.1016/j.invent.2025.100874","DOIUrl":"10.1016/j.invent.2025.100874","url":null,"abstract":"<div><h3>Background</h3><div>The mental health of young adults is deteriorating. Reasons for this are manifold, ranging from biological factors (e.g. entering a vulnerable developmental phase) to crisis-related external events (e.g. COVID-19 pandemic). Accordingly, easily accessible and universal prevention for the young is needed. Mobile Health (mHealth) interventions are on the rise and especially promising for this age group, due to numerous benefits, such as low threshold, temporal and local flexibility and high scalability. However, the effectiveness and acceptance of mHealth interventions as prevention measures are missing empirical evidence.</div></div><div><h3>Method</h3><div>In a two-arm randomised controlled trial design, this study aimed to evaluate the effectiveness of a mental health app, the ‘Mental Health Guide’, primarily on mental health literacy as well as secondary mental health outcomes. <em>N</em> = 322 Participants (81.99 % female, M = 25.55 years, SD = 9.63 years, age range: 15 to 59 years) were either assigned to the intervention group (<em>n</em> = 158), using the Mental Health Guide for 12 weeks, or the wait-list control group (<em>n</em> = 164).</div></div><div><h3>Results</h3><div>The results show a significant intervention effect on mental health literacy for the intervention group in the post assessment (<em>p</em> = .047, <em>d</em> = 0.20), but no at later follow-up time points. Further variables related to mental health indicate various effects, such as improved problematic (<em>p</em> = .018, <em>d</em> = 0.20) and prosocial behaviour (<em>p</em> = .008, <em>d</em> = 0.23) in the intervention group and improved emotion regulation capacities for both groups (<em>p</em> &lt; .001, <em>d</em> = 0.20). Overall, there was a high drop-out rate in the study (up to 80 %), especially in the intervention group.</div></div><div><h3>Conclusion</h3><div>This study contributes valuable insights into the potential effectiveness of mHealth prevention in young adults and gives insights on how such applications are used under very naturalistic settings, laying a foundation for future research in this field. However, generalisability is limited due to selective sample characteristics and a rather high drop-out rate over time.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100874"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145105923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting prosocial behavior and well-being in adolescents through a gamified virtual reality intervention: A randomized controlled trial protocol","authors":"Bryant P.H. Hui ,&nbsp;Tao Zhang ,&nbsp;Jeffrey C.F. Ho ,&nbsp;Sophie Kai Lam Cheng ,&nbsp;Chen Li ,&nbsp;Rosetta Wong ,&nbsp;Sylvia Xiaohua Chen","doi":"10.1016/j.invent.2025.100883","DOIUrl":"10.1016/j.invent.2025.100883","url":null,"abstract":"<div><h3>Background</h3><div>Adolescent well-being is an urgent global concern. While engaging in prosocial behavior has been shown to enhance well-being, traditional interventions are often resource-intensive, contextually limited, and typically delivered in 2D formats. Virtual Reality (VR) offers a novel and immersive alternative by allowing adolescents to experience lifelike social scenarios and practice prosocial behaviors across diverse, everyday contexts.</div></div><div><h3>Objective</h3><div>This protocol outlines a randomized controlled trial to evaluate the feasibility, acceptability, and preliminary effectiveness of a gamified VR-based prosocial intervention, <em>Cradle for Kids</em>, among adolescents.</div></div><div><h3>Methods</h3><div>A total of 396 adolescents aged 10 to 16 will be randomly assigned to one of the three groups: a five-week VR-based intervention, a video-based intervention, or a waitlist control group. Prosocial behaviors and well-being will be assessed at baseline, immediately post-intervention, and at a one-month follow-up, with parents also completing proxy reports of participants' well-being at baseline and post-intervention. Daily diary assessments will also be collected throughout the intervention period. Feasibility and acceptability will be examined via completion rate, retention rate, and participant satisfaction. Data will be analyzed using repeated-measures ANOVA and multilevel modeling.</div></div><div><h3>Discussion</h3><div>To our knowledge, this will be the first trial to evaluate a gamified VR intervention designed to promote prosocial behavior and well-being in adolescents. Theoretically, it will contribute empirical evidence on the potential of immersive VR-based interventions to enhance well-being through prosocial engagement. Practically, if found effective, the program may offer a scalable and resource-efficient tool for schools and community organizations seeking to foster prosocial development in youth.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100883"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences of an internet-delivered treatment of obesity: A qualitative study","authors":"Annika Imhagen ,&nbsp;Stefan Jansson ,&nbsp;Fredrik Söderqvist ,&nbsp;Jan Karlsson ,&nbsp;Marije Galavazi ,&nbsp;Agneta Anderzén Carlsson","doi":"10.1016/j.invent.2025.100876","DOIUrl":"10.1016/j.invent.2025.100876","url":null,"abstract":"","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100876"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring and validating themes of the eHealth Therapeutic Alliance Inventory in digital health interventions: A qualitative analysis","authors":"Ohad Ashur ,&nbsp;Chen Rayan Saar ,&nbsp;Or Brandes ,&nbsp;Amit Baumel","doi":"10.1016/j.invent.2025.100895","DOIUrl":"10.1016/j.invent.2025.100895","url":null,"abstract":"<div><h3>Objective</h3><div>Studies indicate that users can establish a therapeutic alliance (TA) with digital health interventions. However, research examining how TA unfolds in digital settings and its unique facets compared to conventional TA remains limited. This qualitative study aimed to explore and validate preliminary quantitative findings suggesting three distinct themes unique to eHealth TA.</div></div><div><h3>Methods</h3><div>Qualitative data were collected from users of a digital parent training program aiming to explore participants' general experiences with the program. Semi-structured double-blind interviews were conducted (<em>n</em> = 16), and responses to open-ended questions from a larger sample of users were collected (<em>n</em> = 64). Data were thematically analyzed using the six-step framework outlined by Braun and Clarke.</div></div><div><h3>Results</h3><div>In the deductive thematic analysis all three eHealth TA themes were identified – Sense of Relatedness (SR), Application-Induced Accountability (AIA), and Perceived Emotional Investment (PEI), along with the three sub-themes of conventional TA (Goal, Task and Bond). Two eHealth TA themes (SR, AIA) were fully represented in participant's responses, while one (PEI) was only marginally validated. Regarding conventional TA, Goal and Task were fully represented, while Bond was only marginally validated. Validation of eHealth TA themes was further supported by the analysis of the open-ended questions.</div></div><div><h3>Conclusions</h3><div>Findings reinforce prior research, indicating that TA in digital health settings unfolds in distinct ways, and underscoring the need for further exploration of eHealth TA's unique characteristics. Additionally, the study emphasizes potential advantages of employing double-blind methodology in qualitative studies.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100895"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145747057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and initial evaluation of an ultra-brief digital treatment for perinatal depression and anxiety symptoms","authors":"Madelyne A. Bisby ,&nbsp;Noni Jervis ,&nbsp;Alana Fisher ,&nbsp;Amelia J. Scott ,&nbsp;Nickolai Titov ,&nbsp;Blake F. Dear","doi":"10.1016/j.invent.2025.100866","DOIUrl":"10.1016/j.invent.2025.100866","url":null,"abstract":"<div><div>Psychological treatments for perinatal depression and anxiety are effective when delivered in-person or remotely. However, new and expectant mothers face considerable barriers to receiving mental health care, especially on an ongoing basis or when delivered in-person. Very brief digital treatments may be able to support women during this time using less time than existing treatments. The current study reports the development and initial evaluation of a therapist-guided digital ultra-brief treatment for perinatal depression or anxiety. The treatment included one online lesson, supporting resources (e.g., practice exercises), and an optional consultation (telephone or secure messaging) with a clinical psychologist. We examined acceptability, satisfaction, and preliminary efficacy in a single-group trial of women with perinatal depression or anxiety symptoms (<em>N</em> = 47). This was accompanied by focus groups of women with lived experience (<em>N</em> = 9) and semi-structured feedback interviews with treatment participants (<em>N</em> = 7). The treatment was feasible to deliver and associated with high completion (90 %) and satisfaction (85 %) rates. Most participants (61 %) completed the treatment without therapist guidance. At 5-weeks post-baseline, participants reported significant reductions in depression (<em>d</em> = 0.79) and anxiety (<em>d</em> = 0.44), noting that the sample reported mild baseline symptom severity. Several areas of improvement to treatment content, delivery, and look and feel were identified. The study supports ultra-brief digital treatments as an acceptable and potentially efficacious way to support women with perinatal depression or anxiety symptoms.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100866"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment expectations and depressive symptoms in an internet-based intervention for depression. A secondary analysis","authors":"Gwendolyn Wälchli ,&nbsp;Laura Luisa Bielinski ,&nbsp;Oliver Thomas Bur ,&nbsp;Tobias Krieger ,&nbsp;Jan Philipp Klein ,&nbsp;Thomas Berger","doi":"10.1016/j.invent.2025.100869","DOIUrl":"10.1016/j.invent.2025.100869","url":null,"abstract":"<div><h3>Background</h3><div>Treatment expectations are known to influence therapy outcomes, but their role in internet-based interventions (IBIs) for depression remains unclear. While previous research has primarily focused on expectations as a <em>pre-treatment predictor</em> (PTP), emerging evidence suggests that <em>early process predictors</em> (EPPs), including evolving expectations during treatment, may provide more relevant insights into therapeutic outcomes.</div></div><div><h3>Objective</h3><div>This secondary analysis of a factorial trial (Bur et al., 2022) investigates the role of treatment expectations as both a <em>pre-treatment predictor</em> and <em>early process predictor</em> in an internet-based intervention for mild to moderate depression. It also explores the temporal relationship between expectations and depressive symptoms, assessing whether earlier expectations predict later symptom severity and whether depressive symptoms influence subsequent expectations.</div></div><div><h3>Methods</h3><div>Treatment expectancy was measured using the Credibility and Expectancy Questionnaire (CEQ-8; Devilly &amp; Borkovec, 2000; German version: Walach et al. 2008) at baseline (T0), two weeks (T1), and four weeks (T2), while depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9; Kroenke et al., 2001) at the same time points as well as post-treatment (T3). To analyze the relationship between treatment expectations (CEQ-8) and depressive symptoms (PHQ-9 post-treatment), simple regression models were conducted while controlling for baseline PHQ-9 scores. Multiple regression analyses were then used to examine whether CEQ-8 predicted PHQ-9 or vice versa. In addition, as a sensitivity analysis, a cross-lagged panel model (CLPM) was estimated to account for the repeated-measures structure of the data.</div></div><div><h3>Results</h3><div>Baseline treatment expectations did not significantly predict depressive symptoms at post-treatment. However, expectations measured at two weeks (T1) and four weeks (T2) significantly predicted depressive symptoms at T3. The results of the multiple regression analyses indicate that treatment expectations can predict changes in depressive symptoms, whereas the reverse relationship was not observed. The CLPM yielded results that were consistent with the regression analyses, supporting the robustness of the findings.</div></div><div><h3>Conclusions</h3><div>Treatment expectations evolve throughout therapy and appear to function as an independent predictor of symptom improvement rather than merely reflecting symptom severity. Monitoring and addressing patient expectations early in treatment may enhance intervention outcomes. These findings support the inclusion of expectation-based strategies in IBIs to optimize engagement and effectiveness.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100869"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapist characteristics and acceptance of internet-delivered cognitive behavioral therapy: A national cross-sectional survey using the technology acceptance model after ten years of iCBT in Norway","authors":"Reidar Nævdal ,&nbsp;Christiaan Vis ,&nbsp;Robin Maria Francisca Kenter","doi":"10.1016/j.invent.2025.100881","DOIUrl":"10.1016/j.invent.2025.100881","url":null,"abstract":"<div><h3>Background</h3><div>Internet-delivered cognitive behavioral therapy (iCBT) has been available in Norwegian specialist mental health care for a decade. Despite strong evidence and national support, uptake remains limited, with little known about therapists delivering iCBT or factors influencing engagement.</div></div><div><h3>Objective</h3><div>Using an extended Technology Acceptance Model (TAM), this study aimed to provide a national overview of therapists delivering iCBT, their work environment, and acceptance, as well as explore group differences between clinics established through different implementation approaches.</div></div><div><h3>Methods</h3><div>The study identified all therapists using iCBT in routine care. Using a cross-sectional survey, data regarding therapists' characteristics, their context, and TAM constructs was collected. Therapists were grouped by whether their clinics used bottom-up or top-down implementation approaches and compared on all TAM constructs.</div></div><div><h3>Results</h3><div>Sixty-seven therapists were identified as actively delivering iCBT nationally. Of these, 45 therapists from 18 clinics responded (67 % response rate). Therapists were experienced clinicians with varying backgrounds and work environments. High acceptance was found across all TAM dimensions except for Image. Therapists in clinics with structured top-down implementation and ongoing supervision reported highest acceptance.</div></div><div><h3>Conclusion</h3><div>Despite high therapist acceptance of iCBT, experienced loss in professional regard presents a cultural barrier hindering widespread adoption. Despite a decade of use, iCBT remains a small part of routine care. However, successful implementation across diverse therapist backgrounds is achievable, and mandated top-down implementation appears useful when supported by experienced supervision.</div></div><div><h3>Trial registration</h3><div>Haukeland University Hospital e-procotol, project ID: 4696–4696.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100881"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effectiveness and cost-utility of a therapist-guided online intervention provided soon after trauma: Results from a randomized controlled trial","authors":"Maria Bragesjö ,&nbsp;Filip K. Arnberg ,&nbsp;Erik Andersson","doi":"10.1016/j.invent.2025.100886","DOIUrl":"10.1016/j.invent.2025.100886","url":null,"abstract":"<div><div>This study evaluated the cost-effectiveness and cost-utility of a therapist-guided, internet-delivered early intervention for trauma. Exposure to traumatic events is common and can lead to substantial psychological distress, functional impairment, and societal costs. Early psychological interventions have the potential to mitigate these effects. We developed Condensed Internet-delivered Prolonged Exposure (CIPE), a digital intervention delivered within two months of trauma exposure. In a randomized controlled trial (<em>N</em> = 102), CIPE was more effective than a waiting-list control in reducing post-traumatic stress symptoms at post-intervention (3 weeks) and at a prespecified 7-week follow-up while the waiting-list control remained intact (prior to crossover). In this study, we evaluated CIPE from a societal cost perspective, aggregating direct medical costs (healthcare contacts, medication) and indirect costs (sick leave, reduced productivity, domestic loss) with equal weight in total cost calculations using a self-report questionnaire. Cost-effectiveness was assessed using responder status (≥10-point symptom reduction) and subthreshold symptom status on the PTSD Checklist for DSM-5. Cost-utility was assessed using quality-adjusted life years (QALYs) from the EQ-5D. Incremental cost-effectiveness ratios (ICERs) were estimated using bootstrapped regression analyses and visualized in cost-effectiveness planes and acceptability curves. CIPE showed a 95 % probability of being cost-effective at a willingness-to-pay threshold of €939–1181 per additional responder or subthreshold case. The corresponding cost per QALY gained was €2929–3636. Effects were sustained at 12-month follow-up. These findings suggest that therapist-guided digital exposure therapy delivered soon after trauma can reduce symptoms at a relatively low cost to society. Future research should examine CIPE's long-term economic impact and potential for broader implementation.</div></div>","PeriodicalId":48615,"journal":{"name":"Internet Interventions-The Application of Information Technology in Mental and Behavioural Health","volume":"42 ","pages":"Article 100886"},"PeriodicalIF":4.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145465212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}