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Seminars in Thoracic and Cardiovascular Surgery最新文献

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Effects of Intraoperative Support Strategies on Endothelial Injury and Clinical Lung Transplant Outcomes 术中支持策略对内皮损伤和临床肺移植结果的影响
IF 2.6 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-09-01 DOI: 10.1053/j.semtcvs.2022.09.016
{"title":"Effects of Intraoperative Support Strategies on Endothelial Injury and Clinical Lung Transplant Outcomes","authors":"","doi":"10.1053/j.semtcvs.2022.09.016","DOIUrl":"10.1053/j.semtcvs.2022.09.016","url":null,"abstract":"<div><p><span><span>In lung transplantation<span>, postoperative outcomes favor intraoperative use of extracorporeal membrane oxygenation (ECMO) over </span></span>cardiopulmonary bypass<span> (CBP). We investigated the effect of intraoperative support strategies on endothelial injury<span><span><span> biomarkers and short-term posttransplant outcomes. Adults undergoing bilateral lung transplantation with No-Support, venoarterial (V-A) ECMO, or CPB were included. Plasma samples pre- and post-transplant were collected for Luminex assay to measure endothelial injury biomarkers including syndecan-1 (SYN-1), intercellular adhesion molecule-1 (ICAM-1), and matrix metalloprotease-9. Fifty five patients were included for analysis. The </span>plasma level of SYN-1 at arrival in the </span>intensive care unit was significantly higher with CPB compared to V-A ECMO and No-Support (</span></span></span><em>P</em><span> &lt; 0.01). The rate of primary graft dysfunction grade 3 (PGD3) at 72 hours was 60.0% in CPB, 40.1% in V-A ECMO, and 15% in No-Support (</span><em>P</em><span><span> = 0.01). Postoperative plasma levels of SYN-1 and ICAM-1 were significantly higher in recipients who developed PGD3 at 72 hours. SYN-1 levels were also significantly higher in patients who developed acute kidney injury and </span>hepatic dysfunction<span><span><span> after transplant. Postoperative, SYN-1 upon intensive care arrival was found to be a significant predictive biomarker of PGD3, acute kidney injury, and </span>hepatic dysfunction following lung transplantation. CPB is associated with higher plasma concentrations of SYN-1, a marker of endothelial </span>glycocalyx degradation, upon arrival to the intensive care unit. Higher levels of SYN-1 are predictive of end-organ dysfunction following lung transplantation. Our data suggests that intraoperative strategies aimed at modulating endothelial injury will help improve lung transplantation outcomes.</span></span></p></div>","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":"36 3","pages":"Pages 358-368"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10822410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sequential Coronary Artery Bypass Grafts: Flow-based Patency Assessment Criteria 序贯冠状动脉旁路移植术：基于血流的通畅度评估标准
IF 2.6 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-09-01 DOI: 10.1053/j.semtcvs.2024.01.001
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引用次数: 0
Recent Articles in AATS Journals 最近在 AATS 期刊上发表的文章
IF 2.6 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-09-01 DOI: 10.1053/j.semtcvs.2024.08.001
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引用次数: 0
Commentary: It Is Okay to Leave the Dissected Aortic Root Alone, but no Felt or Bio-Glue Please! 评论：可以不切除剥离的主动脉根部，但请不要使用毛毡或生物胶！
IF 2.6 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-09-01 DOI: 10.1053/j.semtcvs.2023.04.001
{"title":"Commentary: It Is Okay to Leave the Dissected Aortic Root Alone, but no Felt or Bio-Glue Please!","authors":"","doi":"10.1053/j.semtcvs.2023.04.001","DOIUrl":"10.1053/j.semtcvs.2023.04.001","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":"36 3","pages":"Pages 301-302"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9489620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discussion to: Twenty-Five Years of Lung Transplantation in Medellín: Overcoming the Challenges of an Emerging Country 讨论：麦德林肺移植二十五年：克服新兴国家的挑战。
IF 2.6 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-09-01 DOI: 10.1053/j.semtcvs.2023.08.001
{"title":"Discussion to: Twenty-Five Years of Lung Transplantation in Medellín: Overcoming the Challenges of an Emerging Country","authors":"","doi":"10.1053/j.semtcvs.2023.08.001","DOIUrl":"10.1053/j.semtcvs.2023.08.001","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":"36 3","pages":"Pages 376-377"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply: What is the Suitable Predictor for Venous Sequential Coronary Grafting? 回复：静脉序贯冠状动脉移植术的合适预测指标是什么？
IF 2.6 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-09-01 DOI: 10.1053/j.semtcvs.2024.03.001
{"title":"Reply: What is the Suitable Predictor for Venous Sequential Coronary Grafting?","authors":"","doi":"10.1053/j.semtcvs.2024.03.001","DOIUrl":"10.1053/j.semtcvs.2024.03.001","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":"36 3","pages":"Page 335"},"PeriodicalIF":2.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140185981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Should Treatment of Mesothelioma Include Surgery? MARS2 Fails to Land. 间皮瘤的治疗应包括手术吗？MARS2 未能着陆
IF 2.6 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-07-17 DOI: 10.1053/j.semtcvs.2024.07.001
Shubham Gulati, Andrea S Wolf, Raja M Flores
{"title":"Should Treatment of Mesothelioma Include Surgery? MARS2 Fails to Land.","authors":"Shubham Gulati, Andrea S Wolf, Raja M Flores","doi":"10.1053/j.semtcvs.2024.07.001","DOIUrl":"10.1053/j.semtcvs.2024.07.001","url":null,"abstract":"<p><p>The presentation of the Mesothelioma and Radical Surgery 2 trial, a randomized controlled trial comparing pleurectomy/decortication to no surgery, injected new data into the contentious discussion surrounding the use of surgery in the management of diffuse pleural mesothelioma. We review the trial results in the context of the existing work surrounding the use of surgery in pleural mesothelioma.</p>","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Articles in AATS Journals 最近在 AATS 期刊上发表的文章
IF 2.5 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-06-01 DOI: 10.1053/j.semtcvs.2024.05.001
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引用次数: 0
Masthead (copyright and information page) 刊头（版权和信息页）
IF 2.5 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-06-01 DOI: 10.1053/S1043-0679(24)00034-0
{"title":"Masthead (copyright and information page)","authors":"","doi":"10.1053/S1043-0679(24)00034-0","DOIUrl":"https://doi.org/10.1053/S1043-0679(24)00034-0","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":"36 2","pages":"Page II"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141242780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary: Old Data Provide New Insights Into the Therapeutic Benefit of Adjuvant Chemotherapy in Non-Small Cell Lung Cancer 评论：旧数据为非小细胞肺癌辅助化疗的治疗效果提供了新见解。
IF 2.5 3区 医学
Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-06-01 DOI: 10.1053/j.semtcvs.2022.11.006
Kyle G. Mitchell MD MSc, Mara B. Antonoff MD
{"title":"Commentary: Old Data Provide New Insights Into the Therapeutic Benefit of Adjuvant Chemotherapy in Non-Small Cell Lung Cancer","authors":"Kyle G. Mitchell MD MSc,&nbsp;Mara B. Antonoff MD","doi":"10.1053/j.semtcvs.2022.11.006","DOIUrl":"10.1053/j.semtcvs.2022.11.006","url":null,"abstract":"","PeriodicalId":48592,"journal":{"name":"Seminars in Thoracic and Cardiovascular Surgery","volume":"36 2","pages":"Pages 271-272"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40695738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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