J Scott Rankin, J Hunter Mehaffey, Danny Chu, Richard Ramsingh, Abhishek Sharma, Vinay Badhwar, Faisal G Bakaeen
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Using contemporary surgical techniques, it is possible to obtain greater than 95% overall early graft patencies that translate into better late outcomes, including improved survival, freedom from myocardial infarction, fewer percutaneous coronary interventions, and redo coronary bypass procedures. The overall goal is to revascularize the 2 most important coronary systems with internal mammary artery grafts, and the rest with radial arteries, depending on the anatomy, experience, and choice of the surgeon. Using highly validated management strategies, early postoperative complications, including the incidence of sternal infections, are extremely uncommon, and in many practices, multi-arterial grafts currently are used in the majority of multivessel patients, including those with concomitant valve disease. Because patencies and outcomes are significantly better than with saphenous vein bypass or percutaneous coronary interventions, referring physicians frequently favor multi-arterial bypass procedures as the primary therapy for patients with prognostically serious multivessel disease. 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引用次数: 0
摘要
冠状动脉搭桥手术不断发展,目前大多数分析都倾向于使用自体活体动脉导管进行冠状动脉移植,以获得更好的长期通畅性和临床疗效。通过双侧乳内动脉(IMA)移植物和双侧桡动脉(RA),有四种极佳的动脉导管可为大多数多血管疾病患者(包括瓣膜疾病患者)提供 "全动脉 "血运重建。利用现代外科技术,可以获得超过 95% 的早期移植物总通畅率,从而改善后期疗效,包括提高生存率、避免心肌梗死、减少经皮冠状动脉介入治疗(PCI)和重做冠状动脉搭桥手术。总体目标是使用 IMA 移植物对两个最重要的冠状动脉系统进行血管再通,并根据解剖结构、经验和外科医生的选择,使用 RA 对其余冠状动脉系统进行血管再通。采用经过高度验证的管理策略后,术后早期并发症(包括胸骨感染)的发生率极低,目前在许多临床实践中,多动脉移植物被用于大多数多血管患者,包括合并瓣膜疾病的患者。由于其通畅性和疗效明显优于大隐静脉搭桥或 PCI,转诊医生通常倾向于将多动脉搭桥术作为预后严重的多血管疾病患者的主要治疗方法。因此,主要使用自体动脉导管的冠状动脉搭桥术应在未来严重冠状动脉粥样硬化的治疗中扮演越来越重要的角色。
Techniques and Results of Multiple Arterial Bypass Grafting: Towards More "Curative" Coronary Revascularizations.
Surgical coronary bypass has evolved continually, and most analyses currently favor performing coronary grafts with autologous living arterial conduits to obtain better long-term patencies and clinical outcomes. With bilateral internal mammary artery grafts and both radial arteries, 4 excellent arterial conduits exist for creating "all-arterial" revascularization in the majority of multivessel disease patients, including those with valve disorders. Using contemporary surgical techniques, it is possible to obtain greater than 95% overall early graft patencies that translate into better late outcomes, including improved survival, freedom from myocardial infarction, fewer percutaneous coronary interventions, and redo coronary bypass procedures. The overall goal is to revascularize the 2 most important coronary systems with internal mammary artery grafts, and the rest with radial arteries, depending on the anatomy, experience, and choice of the surgeon. Using highly validated management strategies, early postoperative complications, including the incidence of sternal infections, are extremely uncommon, and in many practices, multi-arterial grafts currently are used in the majority of multivessel patients, including those with concomitant valve disease. Because patencies and outcomes are significantly better than with saphenous vein bypass or percutaneous coronary interventions, referring physicians frequently favor multi-arterial bypass procedures as the primary therapy for patients with prognostically serious multivessel disease. Thus, coronary bypass using predominantly autologous arterial conduits should play an increasingly important role in the future management of severe coronary atherosclerosis.
期刊介绍:
Seminars in Thoracic and Cardiovascular Surgery is devoted to providing a forum for cardiothoracic surgeons to disseminate and discuss important new information and to gain insight into unresolved areas of question in the specialty. Each issue presents readers with a selection of original peer-reviewed articles accompanied by editorial commentary from specialists in the field. In addition, readers are offered valuable invited articles: State of Views editorials and Current Readings highlighting the latest contributions on central or controversial issues. Another prized feature is expert roundtable discussions in which experts debate critical questions for cardiothoracic treatment and care. Seminars is an invitation-only publication that receives original submissions transferred ONLY from its sister publication, The Journal of Thoracic and Cardiovascular Surgery. As we continue to expand the reach of the Journal, we will explore the possibility of accepting unsolicited manuscripts in the future.