Qi Liu, Wan-Yi Xu, Cen-Cen You, Rong-Gui Zhou, Ying He
{"title":"Enantiospecific 1,3-hydrogen transfer of alkenes and alkynes","authors":"Qi Liu, Wan-Yi Xu, Cen-Cen You, Rong-Gui Zhou, Ying He","doi":"10.1016/j.trechm.2024.08.004","DOIUrl":"https://doi.org/10.1016/j.trechm.2024.08.004","url":null,"abstract":"<p>1,3-Hydrogen (H) transfer of alkenes and alkynes has emerged as an atom-economic transformation in organic synthesis. The reaction usually takes place under mild conditions, avoids the need for external additives, and accommodates a broad range of functional groups. Although 1,3-H transfer was first realized a long time ago, only in recent times have there been more comprehensive and systematic studies on their enantiospecific transformations. This review summarizes the recent advances in enantiospecific 1,3-H transfer of alkenes and alkynes for the generation of centrally and axially chiral molecules. Examples where the enantiospecific 1,3-H transfer occurs inside a tandem reaction system are discussed. This review could inspire more studies on the development of enantiospecific 1,3-H transfer for asymmetric chemistry.</p>","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"12 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subscription and Copyright Information","authors":"","doi":"10.1016/s2589-5974(24)00168-0","DOIUrl":"https://doi.org/10.1016/s2589-5974(24)00168-0","url":null,"abstract":"No Abstract","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"2 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advisory Board and Contents","authors":"","doi":"10.1016/s2589-5974(24)00165-5","DOIUrl":"https://doi.org/10.1016/s2589-5974(24)00165-5","url":null,"abstract":"No Abstract","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"27 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cholesterol-mediated functionalization of liposomes for artificial cell design","authors":"Xin Qiao, Xiaoliang Wang, Xin Huang","doi":"10.1016/j.trechm.2024.08.003","DOIUrl":"https://doi.org/10.1016/j.trechm.2024.08.003","url":null,"abstract":"<p>To achieve functionalized liposomes and their expanding applications in assembling artificial cells and solve problems of poor stability and single structure of liposomes, recent progress in state-of-the-art liposomes has employed cholesterol as an ‘anchor’ to enrich phospholipid membranes with modifications. Cholesterol is widely used because of its capacity for robust hydrophobic interactions with phospholipids. Introducing cholesterol into liposomes renders them more similar to cells. This review summarizes the various designs and applications of cholesterol-based anchors in liposomes, including surface macromolecular modification of liposomes to achieve improved properties and functionalization, cholesterol-mediated liposome membrane fusion, and cholesterol-mediated hierarchical construction of liposomes as artificial cell models. These studies guide artificial cells to reveal the behavior of life and wider applications.</p>","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"5 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad H. Akhdar, Farah B. Cheaib, Farah N. Al-Awar, Nabil M. Halabi, Areej Merhi, Bilal R. Kaafarani
{"title":"ChemCarnival: inspiring future STEM pioneers","authors":"Ahmad H. Akhdar, Farah B. Cheaib, Farah N. Al-Awar, Nabil M. Halabi, Areej Merhi, Bilal R. Kaafarani","doi":"10.1016/j.trechm.2024.08.001","DOIUrl":"https://doi.org/10.1016/j.trechm.2024.08.001","url":null,"abstract":"<p>Contemporary pedagogical research emphasizes the necessity of outreach events to promote and foster science, technology, engineering, and mathematics (STEM) education. This is vital, both in the Middle East and North Africa (MENA) region and worldwide. Here we describe the creation of <em>ChemCarnival</em>, an annual outreach event at the American University of Beirut (AUB) to encourage STEM enthusiasm in the Lebanese community.</p>","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"8 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Single-bacterium modification strategies for photobiocatalytic CO2 reduction","authors":"Yujing Jiang, Hanyu Li, Wenlei Zhu","doi":"10.1016/j.trechm.2024.07.003","DOIUrl":"https://doi.org/10.1016/j.trechm.2024.07.003","url":null,"abstract":"<p>Photosynthetic biohybrid systems (PBS) could efficiently harness solar energy through photosensitizers and facilitate CO<sub>2</sub> fixation via biocatalysts. Enhancing electron generation, transfer, and utilization at the photosensitizer–biocatalyst interface is crucial for the improvement in PBS performance. This forum article evaluates PBS, incorporating diverse photosensitizers and biocatalysts, introducing innovative strategies for enhancing PBS performance.</p>","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"1 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142188005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subscription and Copyright Information","authors":"","doi":"10.1016/s2589-5974(24)00145-x","DOIUrl":"https://doi.org/10.1016/s2589-5974(24)00145-x","url":null,"abstract":"No Abstract","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"83 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142224645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advisory Board and Contents","authors":"","doi":"10.1016/s2589-5974(24)00142-4","DOIUrl":"https://doi.org/10.1016/s2589-5974(24)00142-4","url":null,"abstract":"No Abstract","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"5 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An asymmetric propargylation of cyclopropanols","authors":"","doi":"10.1016/j.trechm.2024.07.001","DOIUrl":"https://doi.org/10.1016/j.trechm.2024.07.001","url":null,"abstract":"No Abstract","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"29 1","pages":""},"PeriodicalIF":15.7,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141946992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}