Chronic Illness最新文献

{"title":"Managing stigma and disclosure of inflammatory bowel diseases for a good life with the disease. An interpretative phenomenological analysis study.","authors":"Anke Erdmann, Christoph Rehmann-Sutter, Florian Schrinner, Claudia Bozzaro","doi":"10.1177/17423953261436465","DOIUrl":"https://doi.org/10.1177/17423953261436465","url":null,"abstract":"<p><p>ObjectivesThe aim of this study is to answer two research questions: 1. How do people with inflammatory bowel disease (IBD) disclose their condition to others? 2. How do non-affected people respond to disclosure of IBD? The findings complement our previous research with people suffering from IBD on their concepts of a 'good life'.MethodsWe conducted 10 qualitative interviews with individuals with IBD and analyzed them with interpretative phenomenological analysis.ResultsParticipants with IBD reported that non-affected people appear to have only marginal knowledge about this disease and they tend to trivialize the illness. They described stigmatizing responses which make them experience shame or lack of dignity. To deal with difficult responses, participants sometimes try to avoid embarrassing situations and limit the information they give others about their illness. Sometimes they break social relationships. They disclose their illness for strategic reasons, for example to generate understanding from their employers. But they also experience understanding from others after revealing their illness.DiscussionOur study expands the evidence on experiences of stigma and the difficulties regarding disclosure in IBD, but also on the positive experiences of disclosure. Future research should focus on developing and evaluating appropriate methods for counseling on stigma and disclosure.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261436465"},"PeriodicalIF":1.8,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carotid artery ultrasound for vascular complications of diabetes: An updated systematic review and meta-analysis.","authors":"Limin Sun, Na Zhang, Hanxing Song, Chong Bi, Xing Chen, Yi Zhou","doi":"10.1177/17423953261436459","DOIUrl":"https://doi.org/10.1177/17423953261436459","url":null,"abstract":"<p><p>ObjectivesSeveral studies have reported the potential association between carotid artery ultrasound index and vascular complications of diabetes. However, the studies of non-significant association results were against the association between carotid artery ultrasound index and vascular complications in diabetes. Therefore, the relationship between carotid artery ultrasound index and vascular complications in diabetes were still debated and controversial.MethodsThe cohort, case-control, or cross-sectional studies were included in the current meta-analysis. The diabetes with and without vascular complications groups in the enrolled studies were compared for the hazard ratio (HR) of diabetic angiopathy (microangiopathy and macroangiopathy) using Review Manager (RevMan). Fourteen studies were included in this meta-analysis. The HR was defined for the 1 mm increase of intima-media thickness of common carotid artery in the ultrasound screening to predict the vascular complications in diabetes.ResultsThe 1-mm increase of intima-media thickness of common carotid artery was significantly associated with a greater log HR of diabetic angiopathy [1.31 (1.19-1.44), Z = 5.41]. However, a substantial heterogeneity was observed in the meta-analysis results.DiscussionThe index of carotid artery ultrasound, such as the increased common carotid artery intima-media thickness, might predict the diabetic angiopathy in the current meta-analytic results.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261436459"},"PeriodicalIF":1.8,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"#MultipleSclerosis: Artificial intelligence-based sentiment and content analysis of Tweets.","authors":"Esra Uslu, Nazmiye Yıldırım, Emrah Atılgan","doi":"10.1177/17423953261440371","DOIUrl":"https://doi.org/10.1177/17423953261440371","url":null,"abstract":"<p><p>ObjectivesThe aim is to uncover the perspectives of Twitter users on Multiple Sclerosis (MS) in English tweets by: (i) determining the sentiment of the text (ii) identifying the discussed topics.MethodsThe tweets were scanned in April 2023 using the keywords \"multiple sclerosis, multiplesclerosis\". Artificial intelligence-based sentiment analysis was conducted on a total of 1168 tweets and content analysis was performed on 17.4% of these tweets.ResultsTweets of 44% are positive and 22.3% are negative sentiment. As a result of content analysis, three themes and their sub-themes were identified: (i) announcement sharing: invitation to support, promotion of academic publications, (ii) information sharing: information providers, information seekers, news providers, (iii) experience sharing: challenging MS, facilitated MS, emotionally impactful MS, comparative MS, misunderstood MS. Subjective content such as experiences is shared less frequently compared to objective content such as announcements and information.DiscussionThe findings of this study can serve as a guiding factor in supporting positive views, managing negative views, and promoting the expression of subjective experiences.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261440371"},"PeriodicalIF":1.8,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosocial stressors and SLE flares: A grounded theory based on Iranian women's lived experiences.","authors":"Haniyeh Zeraatkar, Reza Rostami, Keyvan Salehi, Abdolrahman Rostamian","doi":"10.1177/17423953261436470","DOIUrl":"https://doi.org/10.1177/17423953261436470","url":null,"abstract":"<p><p>ObjectiveSystemic lupus erythematosus (SLE) flares are psychosocially influenced, but there are few culturally sensitive models. This study aims to explore psychosocial factors contributing to lupus flares in women and co-construct a novel framework, grounded in their lived experiences, to guide clinical practice.MethodsUtilizing Charmaz's constructivist grounded theory, we conducted a comprehensive study that included semi-structured interviews with 20 Iranian women who have SLE. Iterative open, focused, and theoretical coding was used to analyze data, with reflexive practices applied to address researchers' cultural assumptions and maintain rigor. Thematic saturation was achieved, situating the developing model within participants' lived experiences.ResultsA new four-domain model was constructed, representing a cyclical process reflecting lupus flare susceptibility. Predisposing Conditions consisted of marital dissatisfaction (e.g., felt spousal invalidation) and extrinsic stressors, with low socio-cultural status (economic distress, cultural divorce taboos) and stressful life events (infidelity, coerced marriages) shaping heightened distress. Mediating Factors-unresolved grief, sleep disturbance, and alexithymia-were viewed to exacerbate emotional and physiological reactions, with sleep disturbance often described by participants as coinciding with inflammatory markers. Responses included non-adaptive illness perception (e.g., \"it is uncontrollable and there is no cure\"), damaged sense of self, and conflicted parental roles, capturing socio-cultural effects. The Implication was difficulty in psychological adjustment to illness, linked with flare. Participants' accounts highlighted a recurring theme linking relational stressors to illness misperceptions, shaped by marital conflict and perceived lack of support.ConclusionsThis culturally informed model reveals new associations among socio-cultural stressors, such as divorce taboos, and lupus flare vulnerability among Iranian women. While acknowledging limitations (the potential influence of anti-inflammatory medications on participants' lived experiences, and also most participants were from lower socio-economic backgrounds), it suggested interventions (e.g., couple therapy, sleep therapy, grief counseling) and research on inflammatory markers. Reflexive grounding underpins equitable progress in SLE care.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261436470"},"PeriodicalIF":1.8,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ups and downs of receiving diabetic-related services in Iran during the COVID-19 pandemic: A qualitative study.","authors":"Seyedeh Tahereh Afrah, Mahlagha Dehghan, Hossein Mirzaei, Mohammad Hossein Gozashti, Vahid Reza Borhaninejad, Ali Sharifi, Hamid Sharifi","doi":"10.1177/17423953261437133","DOIUrl":"https://doi.org/10.1177/17423953261437133","url":null,"abstract":"<p><p>ObjectivesThis study aimed to investigate the obstacles, problems, and facilitating factors in receiving healthcare services for patients with diabetes during the COVID-19 pandemic in Iran.MethodsA total of 18 patients with diabetes, 3 family members of the patients, and 10 healthcare staff members, using purposive sampling, with maximum diversity in demographic variables, were interviewed. Semi-structured in-depth interviews were used to collect the data. Data were analyzed using the content analysis method with Graneheim and Lundman's approach. Guba and Lincoln's criteria were used to measure the quality and validity of the data.ResultsWe extracted one theme, two sub-themes, four secondary categories, and 13 primary categories (443 codes). The theme of the ups and downs of receiving services was divided into two sub-themes obstacles and challenges of receiving services, and facilitators for receiving services; four secondary categories: obstacles and challenges of seeking service from the patients, and the patient's family, obstacles and challenges of receiving services by the system, solutions made by patients to solve psychological problems caused by the epidemic and facilitators to receive healthcare services from the system.DiscussionGiven the disruptions caused by COVID-19 and similar epidemics, it is crucial to develop strategies for improving healthcare access for people with diabetes. Identifying barriers and facilitators to service access is essential for policymakers to formulate more effective plans.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261437133"},"PeriodicalIF":1.8,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A diary study of UK workers self-managing long-term health conditions.","authors":"Sally Hemming, Fehmidah Munir","doi":"10.1177/17423953261437134","DOIUrl":"https://doi.org/10.1177/17423953261437134","url":null,"abstract":"<p><p>PurposeLittle is known about characteristics of workers' self-management of long-term health conditions or their changeability. Specifically, little insight exists into self-management confidence and specifically whether engaged workers are likely to be confident in self-managing a long-term condition at work.MethodsUsing an online diary with six timepoints over a 10-week period, UK workers with long-term health conditions were asked to report on their self-management confidence and work engagement fortnightly.ResultsSixty-seven workers made at least one diary entry. Fifty-seven participated at timepoint 1, 39 in three or more timepoints and 11 in all six. Multi-level modelling revealed workers' self-management confidence not significantly changing over time. Consistent with one study hypothesis, modelling revealed work engagement having an effect on people's self-management confidence.ConclusionWork engagement might promote workers' long-term condition self-management. Providing support for work engagement could benefit people's self-management confidence although more research is needed to ascertain the relationship between the variables.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261437134"},"PeriodicalIF":1.8,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of potential biomarkers of fibromyalgia using a proteomic approach in peripheral blood mononuclear cells.","authors":"María Teresa Vega-Ramírez, José Luis Maldonado-García, Enrique Becerril-Villanueva, Rodrigo Arreola, Enrique Estudillo, Alberto Fernández, José Miguel Elizalde-Contreras, Eliel Ruiz-May, Danelia Mendieta, Gilberto Pérez-Sánchez, Lenin Pavón","doi":"10.1177/17423953261437132","DOIUrl":"https://doi.org/10.1177/17423953261437132","url":null,"abstract":"<p><p>Fibromyalgia (FM) is a chronic disorder characterized mainly by pain, fatigue, and sleep disturbances. Its etiology and pathophysiology are not yet well understood, but central sensitization is considered to be the main mechanism involved, although genetic, immune, and hormonal factors have also been proposed to play an essential role in the disease. Currently, fibromyalgia is diagnosed by clinical examination of the patient and the use of clinimetric scales. However, there are no laboratory tests for it, so finding potential biomarkers of this condition will be of great utility for its diagnosis. The aim of this work was to find potential biomarkers of fibromyalgia in peripheral blood mononuclear cells (PBMCs) from patients with FM. Using Tandem Mass Tag (TMT) mass spectrometry coupled to Synchronized Precursor Selection (SPS-MS3), we obtained a differential proteomic profile of PBMCs from fibromyalgia patients. The proteomic profile contains 251 proteins, of which 47 were dysregulated in fibromyalgia patients and could be potential biomarkers of this disorder.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261437132"},"PeriodicalIF":1.8,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing ME/CFS following mononucleosis with Long COVID.","authors":"Leonard A Jason, Jacob Furst, Ben Z Katz","doi":"10.1177/17423953251347108","DOIUrl":"https://doi.org/10.1177/17423953251347108","url":null,"abstract":"<p><p>ObjectivesLong COVID following SARS-CoV-2 and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) following infectious mononucleosis (IM) are examples of post-infectious chronic illnesses. Behavioral and pathophysiological underpinnings of both ME/CFS following IM and Long COVID are not well understood.MethodsWe studied ME/CFS development following IM in a diverse group of college students who were enrolled before the onset of IM. We categorized those meeting either moderate or severe ME/CFS criteria. We subsequently recruited a matched sample of those infected with SARS-CoV-2, some of whom recovered and others of whom developed Long COVID. We compared and contrasted ME/CFS and Long COVID following IM and SARS-CoV-2 infection in terms of somatic symptoms, coping strategies, depression and anxiety symptoms, and functional status.ResultsIn general, the Long COVID group's symptom burden was less than that of the Severe ME/CFS group but more than that of the Moderate ME/CFS group.DiscussionThese findings may allow investigators a better understanding of these post-viral illness pathophysiologies.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953251347108"},"PeriodicalIF":1.8,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of liver cirrhosis on the clinical profile and outcomes in community-acquired pneumonia: A systematic review.","authors":"David Saavedra, Andrés Estupiñan-Bohórquez, Fabian Figueroa, Emiro Buendia, Natalia Alfonso-Arrieta, Luis Machado-Contreras, Diego Viasus, Jordi Carratalà","doi":"10.1177/17423953261436458","DOIUrl":"https://doi.org/10.1177/17423953261436458","url":null,"abstract":"<p><p>ObjectiveCommunity-acquired pneumonia (CAP) is a serious infection in patients with cirrhosis. This study aimed to describe clinical features of patients with cirrhosis and CAP, and to determinate whether cirrhosis is consistently associated with poor outcomes.MethodsDatabases were systematically searched for full-text articles comparing patients with and without cirrhosis with CAP and evaluating the impact of cirrhosis on clinical profile and outcomes, from inception to February 2021.ResultsTotals of 1485 and 114740 patients with cirrhosis and without cirrhosis with CAP were included, respectively. Patients with cirrhosis had different characteristics and more severe disease at admission compared to patients without cirrhosis (hypotension, altered mental status, hyponatremia, hypoalbuminemia were more frequent in patients with cirrhosis). <i>Streptococcus pneumoniae</i> was more frequently identified as the causative pathogen of CAP in patients with cirrhosis, and bloodstream infections were also more common. Likewise, risk of intensive care unit admission and mortality was higher in patients with cirrhosis than in patients without cirrhosis (range 11.1%-23.3% versus 8.8%-17.2% and 2.7%-23% compared with 14.4%-34.5%, respectively).DiscussionPatients with cirrhosis and CAP have a poorer prognosis than patients without cirrhosis. Information on the clinical features of CAP in patients with cirrhosis and on risk factors for poor outcomes remains limited.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261436458"},"PeriodicalIF":1.8,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147628891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new chapter in diabetes education: Qualitative reflections on type 5 diabetes recognition and response.","authors":"Rudy Kurniawan, Debby Syahru Romadlon","doi":"10.1177/17423953261436468","DOIUrl":"https://doi.org/10.1177/17423953261436468","url":null,"abstract":"<p><p>ObjectivesThe 2025 recognition of type 5 diabetes by the International Diabetes Federation has significant implications for healthcare professionals, particularly diabetes educators. This study explores educators' perceptions and responses to this emerging classification, focusing on undernourished populations in low-resource settings.MethodsA qualitative descriptive design was used, with semi-structured interviews conducted with 16 certified diabetes educators in Indonesia, including nurses, nutritionists, pharmacists, and doctors. Interviews were held in April and May 2025, and data were analyzed thematically using Braun and Clarke's framework.ResultsFour themes emerged: (1) <i>Early-stage Awareness</i><b>,</b> educators were unfamiliar with the classification but recognized similar clinical patterns; (2) <i>We're Not Prepared</i><b>,</b> highlighting gaps in training and resources; (3)Context<i>Matters</i>, linking type 5 diabetes to malnutrition and socioeconomic inequities; and (4) <i>Ready to Respond, If Equipped</i>, with educators expressing willingness to adapt if provided with appropriate training. Participants also emphasized the need for national education programs, culturally relevant materials, and cross-sector collaboration.DiscussionWhile educators' preparedness is limited, their willingness to respond is strong. Targeted training, culturally relevant resources, and collaborative support are essential for effective education. Future research should evaluate the effectiveness of these strategies across different settings.</p>","PeriodicalId":48530,"journal":{"name":"Chronic Illness","volume":" ","pages":"17423953261436468"},"PeriodicalIF":1.8,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147628885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}