Laryngoscope Investigative Otolaryngology最新文献

{"title":"Evaluation of the Peripheral Vestibular System due to Inner Ear Barotrauma in the Hyperbaric Environment","authors":"Ömer Bozkurt,&nbsp;Selis Gülseven Güven,&nbsp;Memduha Taş,&nbsp;Şule Yılmaz,&nbsp;Ahmet Köder,&nbsp;Erdoğan Bulut","doi":"10.1002/lio2.70241","DOIUrl":"https://doi.org/10.1002/lio2.70241","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The aim of this study was to investigate changes that may occur in the peripheral vestibular system due to inner ear barotrauma in self-contained underwater breathing apparatus (SCUBA) divers exposed to hyperbaric environments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective study was conducted on 45 healthy volunteers. In this study, after otologic and audiological examinations were performed on two groups as control (<i>n</i> = 24) and SCUBA (<i>n</i> = 21), cervical vestibular evoked myogenic potentials (c-VEMP) were evaluated for peripheral vestibular system functions. The SCUBA group comprised individuals who had completed a minimum of 75 dives and held a World Confederation of Underwater Activities 2 certificate. Statistical analysis was performed on immittance metric measurements, pure-tone hearing thresholds (0.5–18 kHz), and P1-N1 latencies and amplitudes from c-VEMP tests.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The SCUBA group demonstrated statistically significant differences in pure-tone low and high frequency thresholds within the normal hearing range compared to the control group (<i>p</i> = 0.001). The c-VEMP responses showed statistically significant prolongation of P1-N1 latencies in right ears and N1 latencies in left ears in the SCUBA group (<i>p</i> &lt; 0.05), along with a statistically significant increase in amplitudes (<i>p</i> = 0.0001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Based on our findings, the increased amplitudes in c-VEMP responses observed in SCUBA divers exposed to hyperbaric environments suggest enhanced saccular plasticity, likely resulting from barotrauma effects on otolith structures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>3.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144869542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety, Depression, and Disease Burden in Idiopathic Subglottic Stenosis","authors":"Alexa N. Pearce,&nbsp;Tory McKnight,&nbsp;Peter Eckard,&nbsp;Soroush Farsi,&nbsp;Peyton Pinkus,&nbsp;Olivia Speed,&nbsp;Ozlem E. Tulunay-Ugur","doi":"10.1002/lio2.70228","DOIUrl":"https://doi.org/10.1002/lio2.70228","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Idiopathic subglottic stenosis (iSGS) is a chronic, debilitating condition leading to significant changes in quality of life This study aims to describe the comorbidity of anxiety/depression symptoms and iSGS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients with iSGS were surveyed using verified measures of physical symptom severity and mental health status, including the Dyspnea Index (DI), Voice Handicap Index (VHI), General Anxiety Disorder-7 scale (GAD-7), Patient Health Questionnaire-9 (PHQ-9), Rosenberg Self-Esteem Scale (RSE), and Short Form-12 (SF-12).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-seven iSGS patients completed surveys (27/66, 40.9%). All but one were female, and the mean age was 53.8 (range 35–73). A total of 70 surgeries had been performed for treatment of iSGS, with a mean of 2.8 surgeries per person (range 0–15). Fourteen patients (51.9%) reported that iSGS impacts their ability to complete activities of daily living. Thirteen patients (48.1%) reported an impact on their ability to communicate. The mean patient-reported impact level of iSGS on anxiety/depression was 25.5/100. The mean PHQ-9 score was 5.6 in the overall cohort and 9.5 in those with diagnosed or suspected depression/anxiety. The mean GAD-7 score was 4.7 for the overall cohort and 8.3 for patients who reported a suspected or diagnosed mental health condition. DI and GAD-7 scores were mildly positively correlated (<i>r</i>^<i>2</i> = 0.23), as well as DI and PHQ-9 scores (<i>r</i>^<i>2</i> = 0.30).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study demonstrates a small association between symptoms of anxiety, depression, and idiopathic subglottic stenosis. Providers should have a low threshold for administering mental health screening tools and making psychology referrals when needed.</p>\u0000 \u0000 <p><b>Level of Evidence:</b> III.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70228","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144869920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Perceptions of Hypoglossal Nerve Stimulation on Social Media","authors":"Ali M. Baird,&nbsp;Grant S. Owen,&nbsp;Alana Ravasio,&nbsp;Lindsay Fleischer,&nbsp;Michael J. Hutz","doi":"10.1002/lio2.70236","DOIUrl":"https://doi.org/10.1002/lio2.70236","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>With increased direct-to-consumer marketing, there is a demand by patients for more information regarding hypoglossal nerve stimulation (HNS) therapy. There is also concern about the quality of the educational content available. The aim of this study was to examine social media to obtain patient perceptions of HNS therapy, while a secondary aim was to determine the prevalence of posts by physicians about HNS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Posts from Instagram, X, and Facebook from June 2022 through December 2022 were included. Keywords such as hypoglossal nerve stimulation, upper airway stimulation, and inspire therapy were searched. A standardized classification system was used to group posts based on perspective and the media utilized; post purpose and post tone (positive, negative, or neutral) were also evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>497 posts were included, with 451 (90.7%) from X, 31 (6.2%) from Instagram, and 15 (3.0%) from Facebook. Post authorship was 34.8% by healthcare organizations, 19.3% by patients, 14.3% by medical supply companies, and only 7.0% authored by physicians. Posts written by patients (<i>n</i> = 96) were significantly more likely to have a positive tone, whereas posts written by other authors (<i>n</i> = 401) were more likely to have a neutral tone (<i>p</i> = 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Patients demonstrated positive perceptions of HNS therapy across multiple social media sites. Posts written by physicians comprised a minority of public social media posts regarding HNS; making it important for physicians to consider taking on an active role in social media.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level 4.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70236","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144853802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Atypical Anatomical Variation in Facial Nerve Position: Temporal Branch Lateral and Main Trunk Medial to the Retromandibular Vein in a Series of Three Cadaveric Cases With Clinical Implications","authors":"Andrej Suchomlinov,&nbsp;Geoffroy Noel,&nbsp;Amir Moradi","doi":"10.1002/lio2.70233","DOIUrl":"https://doi.org/10.1002/lio2.70233","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The position of the retromandibular vein relative to the facial nerve branches can vary among individuals, adding a layer of complexity to surgical planning. In some cases, the vein may cross over or under certain nerve branches, necessitating meticulous dissection to avoid vascular or neural damage. Understanding these variations is critical for optimizing surgical outcomes, minimizing complications, and ensuring the preservation of both vascular and neural integrity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>During the routine dissection of the right hemi-faces of 49 human donor bodies preserved for educational use, an unusual anatomical relationship between the extratemporal facial nerve and the retromandibular vein was observed and recorded in three cases (6%). The facial skin flaps were retracted laterally, and the parotid gland was meticulously dissected to expose and examine the nerves and vessels. The retromandibular vein's pathway was traced to identify the main trunk and branches of the extratemporal facial nerve within the parotid gland. The dissection also included the auriculotemporal nerve and the superficial temporal artery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In all three cases, a single facial nerve trunk was identified, with its branching pattern classified as Type V and VI according to Davis (1956) in two cases; in one of the cases, the trifurcation of the main trunk of the facial nerve was observed. The extratemporal facial nerve followed an atypical route, passing deep (medial) to the retromandibular vein, while its temporal branch ran superficially (lateral) to the retromandibular vein.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The aforementioned atypical course of the temporal branch places the nerve at a greater risk of injury during the surgical procedures. Recognizing and accounting for such variations is critical in minimizing complications and ensuring patient safety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level 4 (case-series).</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70233","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144853801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-Related Variability in the Perception of Symptoms Associated With Common Otolaryngologic Complaints","authors":"Sabrina K. Wagner,&nbsp;Jakob L. Fischer,&nbsp;Alvaro Navarro,&nbsp;Lily Trinh,&nbsp;Waleed M. Abuzeid,&nbsp;Ian M. Humphreys,&nbsp;Nadeem A. Akbar,&nbsp;Sharan Shah,&nbsp;Jivianne T. Lee,&nbsp;Tara Wu,&nbsp;John S. Schneider,&nbsp;Edward D. McCoul,&nbsp;Charles A. Riley,&nbsp;Anthony M. Tolisano","doi":"10.1002/lio2.70235","DOIUrl":"https://doi.org/10.1002/lio2.70235","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the differences in the symptoms associated with common otolaryngology complaints between male and female patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Between June 2020 and July 2023, a multi-institutional cross-sectional study was performed at six tertiary academic otolaryngology practices using semantics-based questionnaires to assess the symptoms patients associate with the complaints of sinus infection, reflux, congestion, and dizziness. Patients selected symptoms from lists of proposed terms to describe the various conditions. The primary outcome measure was sex-related differences in respondent symptom selection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Four separate questionnaires were completed by a total of 1495 patients (46.0% male, 54.0% female). Female patients more often described sinus infection using pain-related symptoms (difference 8.8%; 95% CI, 2.8% to 14.8%) and systemic-related symptoms (difference 10.2%; 95% CI, 2.3% to 18.2%), reflux using pain-related symptoms (difference 18.3%; 95% CI, 3.6% to 41.7%) and sensory-related symptoms (difference 13.1%; 95% CI, 2.5% to 23.7%), and dizziness using vision-related symptoms (13.2%; 95% CI, 1.9% to 24.6%) compared to male patients. Female patients selected individual symptoms within the pain-related domain more often than male patients to describe congestion. Few differences per questionnaire were identified based on geographic location.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Sex-related differences exist in how patients describe common otolaryngologic complaints. Women more commonly associate pain-related symptoms with sinus infection and reflux, sensory-related symptoms with reflux, and vision-related symptoms with dizziness. A more nuanced understanding of how men and women describe complaints may lead to more effective, patient-centered care within otolaryngology.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>4.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70235","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144853809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Auriculotemporal Nerve: A Comprehensive Review of Its Anatomical Variation and Clinical Manifestations","authors":"Alec Kadrie,&nbsp;Patrick Toomey,&nbsp;Joseph Callaway,&nbsp;Marion Boyd Gillespie,&nbsp;John D. Boughter Jr.","doi":"10.1002/lio2.70238","DOIUrl":"https://doi.org/10.1002/lio2.70238","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Various studies have described anatomical variations of the auriculotemporal nerve (ATN), starting with its initial nerve roots and relationship to the middle meningeal artery (MMA). Despite its crucial role in innervating various regions, the precise anatomical course of ATN and its variants remains uncertain. This study aims to provide a comprehensive review of the ATN, including its anatomical course, variations, and clinical significance, particularly in relation to head and neck surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic literature review was conducted using Medline, Embase, and PubMed databases to identify all articles describing the clinical anatomy of ATN. This search strategy adhered to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines. English-language and human studies were selected. Additionally, dissections were performed on three human cadavers to obtain representative images.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>ATN exhibited 1–5 roots, most commonly two (52%), relevant to surgical planning and perineural tumor spread. An inferior alveolar root origination was present in 32.6% of specimens, potentially contributing to unexpected anesthesia or neuralgia. ATN enclosed the MMA in 72.2%, often forming a triangle/V-shaped (61.4%) or “buttonhole” (1.7%) configuration. TMJ innervation was present in all specimens, with 5.8% of branches penetrating the lateral pterygoid, implicating TMJ pain. ATN branches crossed the superficial temporal artery in 73% of cases, relevant to migraine decompression. Parotid branches originated 2–16 mm from the tragus, impacting Frey's syndrome and tumor tracking. Facial nerve communication (&gt; 90%) and greater auricular nerve connection (up to 30%) may underlie atypical facial pain and extended anesthesia fields.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our review reveals considerable diversity in ATN origins, branching patterns, and relationships with adjacent vessels, challenging traditional anatomical depictions. Understanding these variations is crucial for managing compression and entrapment syndromes like temporomandibular disorder and surgical procedures such as parotidectomy, where iatrogenic damage can lead to complications such as Frey Syndrome.</p>\u0000 \u0000 <p><b>Level of Evidence:</b> 3.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70238","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144853800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head and Neck Cancer: Trends and Geographical Distribution of Head and Neck Cancer at a Tertiary Hospital in Northern Tanzania","authors":"Marco R. Magwizi,&nbsp;Michael P. Kayuza,&nbsp;Angela N. Msele,&nbsp;Jesca G. Lyimo,&nbsp;Petro J. Nsalu,&nbsp;Alex Mremi,&nbsp;Philbert P. Mtenga,&nbsp;Desderius C. Chussi,&nbsp;Kenneth J. Mlay","doi":"10.1002/lio2.70234","DOIUrl":"https://doi.org/10.1002/lio2.70234","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Head and neck cancers (HNCs) are the 6th most common cancer diagnosis and mortality worldwide, with a case fatality rate of 51% per annum. In Tanzania, HNC incidence and mortality rates are 4% per annum, with a case fatality rate of 69% per annum. Despite a global rise in HNC cases, data on trends and geographical distribution in Tanzania remain limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methodology</h3>\u0000 \u0000 <p>This was a hospital-based cross-sectional study that included all patients with histologically confirmed HNC at the Kilimanjaro Christian Medical Centre (KCMC) cancer registry who received care from 2013 to 2023. Analysis was done using Statistical Package for Social Sciences version 25. A simple linear regression model was used to analyze trends in terms of gender, age group, and cancer subtype age.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The overall trend of HNCs increased over time (<i>R</i>² = 0.847, <i>p</i> &lt; 0.001). The increase was in both genders, males (<i>R</i>² = 0.76, <i>p</i> &lt; 0.001) and females (<i>R</i>² = 0.87, <i>p</i> &lt; 0.001), respectively, but is slightly higher in males as compared to females. The trend of HNC in the age group 45–59 years (<i>R</i>² = 0.027, <i>p</i> = 0.035) was increasing over time, while remaining fairly constant in the age group below 44. All cancer subtypes, with the exception of laryngeal cancer, showed a significant positive trend: lip and oral cavity (<i>R</i>² = 0.735, <i>p</i> = 0.001), nasal cavity and nasopharynx (<i>R</i>² = 0.462, <i>p</i> = 0.021), oropharyngeal (<i>R</i>² = 0.797, <i>p</i> &lt; 0.001), hypopharyngeal (<i>R</i>² = 0.497, <i>p</i> = 0.015), and saliva gland (<i>R</i>² = 0.697, <i>p</i> = 0.001). Over half of HNC patients (52.1%) came from Kilimanjaro.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>HNC cases are increasing, with notable variations by gender, age, and cancer subtype. Most patients were from Kilimanjaro, highlighting regional disparities and the need for targeted interventions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>IV.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70234","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144832752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilizing Modified Barium Swallow Impairment Profile (MBSImP) to Characterize Swallowing Function Following Total Laryngectomy","authors":"Sana Smaoui,&nbsp;Leyn Bashar Shakhtour,&nbsp;Tatiana Ferraro,&nbsp;Timothy Brandon Shaver,&nbsp;Bint-E Z. Awan,&nbsp;Tristan Jordan,&nbsp;Jennifer Schottler,&nbsp;Rebecca Boersma,&nbsp;Robert Dewey,&nbsp;Joseph F. Goodman","doi":"10.1002/lio2.70227","DOIUrl":"https://doi.org/10.1002/lio2.70227","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>We aim to determine the frequency of altered swallowing physiology for ratable components of the 17-component grading system, the Modified Barium Swallow Impairment Profile (MBSImp), in its current validated state for a cohort of patients post total laryngectomy (TL).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Retrospective study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Otolaryngology Head &amp; Neck Surgery, The George Washington University Hospital and George Washington University Medical Faculty Associates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>All participants received a VFSS as part of standard care, which was scored post hoc using the MBSImP protocol and scoring metric by two blinded speech-language pathologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Due to anatomical changes post-TL, Components 6, 8, 9, 10, and 11 of the MBSImP were not rated. Efficiency concerns were most prevalent with functional deficits noted for: pharyngeal stripping wave, pharyngoesophageal segment opening, tongue base retraction, pharyngeal residue, and esophageal clearance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our work aims to provide further insight into the swallowing characteristics of TL as measured using the MBSImP. A high frequency of biomechanical impairment was identified in this cohort of patients. Although the MBSImP is a validated tool its application to the reconstructed anatomy following TL is not precise and should be regarded with caution in clinical settings. Further work is needed to modify definitions of the MBSImP components and inclusion of additional features that can more accurately describe post-TL dysphagia.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70227","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saddle Nose in Granulomatosis With Polyangiitis (GPA) vs. Non-GPA Patients With Septal Perforations","authors":"Nitish Kumar,&nbsp;Pedro Lança Gomes,&nbsp;Savannah Jett,&nbsp;Stephen F. Bansberg,&nbsp;Michael J. Marino,&nbsp;Devyani Lal,&nbsp;Amar Miglani","doi":"10.1002/lio2.70217","DOIUrl":"https://doi.org/10.1002/lio2.70217","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Saddle nose deformity (SND) can be associated with nasal septal perforation (NSP). Both SND and NSP are observed in granulomatosis with polyangiitis (GPA) patients. This study aimed to compare the prevalence and severity of SND in GPA vs. non-GPA patients with NSP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methodology</h3>\u0000 \u0000 <p>NSP patients who visited tertiary rhinology or facial plastic surgery clinics from January 2010 through December 2023 were grouped into GPA and non-GPA cohorts. The area of NSP, SND incidence, and SND severity (Daniel and Brenner's classification) were compared between the cohorts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 168 patients identified with NSP, 18 had GPA and 150 had non-GPA diagnoses. Twelve GPA patients and 10 non-GPA patients had SND. The odds ratio for SND association in GPA patients with NSP vs. non-GPA patients was 31.3 (95% CI: 9.5–102.9), and 19.4 (95% CI: 4.3–87.7) after controlling for the NSP area. GPA patients with SND had a larger NSP area (median 670 mm², IQR: 315.5–1061.3) compared to non-GPA patients with SND (175.3 mm², 113.1–204.1; <i>p</i> &lt; 0.001). The severity of SND was similar between GPA and the non-GPA group (<i>p</i> = 0.09). The area of NSP did not predict the severity of SND (<i>p</i> = 0.17).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>GPA diagnosis was associated with larger NSPs and a higher risk of SND compared to non-GPA etiologies; however, the severity of saddling did not differ between GPA and non-GPA etiologies. GPA is an independent risk factor associated with SND irrespective of the size of septal perforation. The NSP area did not predict the severity of SND.</p>\u0000 \u0000 <p><b>Level of Evidence:</b> 4.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70217","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airway Compromise in Adults Following Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-Analysis.","authors":"Anuja H Shah, Emily A Clementi, Kelsey Limage, Earl H Harley","doi":"10.1002/lio2.70215","DOIUrl":"10.1002/lio2.70215","url":null,"abstract":"<p><strong>Objective: </strong>Postoperative airway compromise is a rare but significant complication following anterior cervical discectomy and fusion (ACDF). This systematic review and meta-analysis aims to determine the incidence of airway compromise in ACDF patients and identify associated risk factors to guide otolaryngologists in optimizing the airway.</p><p><strong>Data sources: </strong>Following PRISMA guidelines, CINAHL, Cochrane Library, PubMed, and Scopus were searched from inception to July 10, 2024.</p><p><strong>Review methods: </strong>Articles reporting the incidence of airway complications following ACDF were included. Primary outcome measures included proportions (%) and odds ratios (OR) with 95% confidence intervals (CI).</p><p><strong>Results: </strong>Of 449 abstracts identified, 42 studies (<i>N</i> = 960,092) were included. Among ACDF patients, the incidence of airway compromise was 0.78% [95% CI: 0.59-0.99], with unplanned reintubation occurring in 0.45% [95% CI: 0.35-0.57], delayed extubation in 1.5% [95% CI: 0.90-2.1], and tracheotomy in 0.54% [95% CI: 0.05-1.5] of patients. Patients who experienced airway compromise following ACDF demonstrated increased odds of having diabetes mellitus (OR: 2.05 [95% CI: 1.61-2.60]; <i>p</i> < 0.00001), pulmonary disease (OR: 3.44 [95% CI: 2.41-4.93]; <i>p</i> < 0.00001), and bleeding disorders or anticoagulant use at the time of surgery (OR: 3.06 [95% CI: 2.54-3.69]; <i>p</i> < 0.00001). ASA class 3 or 4 (OR: 4.55 [95% CI: 3.28-6.31]; <i>p</i> < 0.00001) and multilevel fusion (OR: 2.33 [95% CI: 1.41-3.84]; <i>p</i> = 0.001) were more common among those who experienced airway compromise.</p><p><strong>Conclusions: </strong>Postoperative airway compromise is a rare but potentially lethal complication of ACDF. Preoperative identification of patient risk factors allows for tailored perioperative management by otolaryngologists and spine surgeons, minimizing the occurrence of airway compromise.</p>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":"e70215"},"PeriodicalIF":1.7,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12329917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}