Physical and Engineering Sciences in Medicine最新文献

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ICG signal denoising based on ICEEMDAN and PSO-VMD methods. 基于 ICEEMDAN 和 PSO-VMD 方法的 ICG 信号去噪。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-12-01 Epub Date: 2024-08-08 DOI: 10.1007/s13246-024-01467-0
Xinhai Li, Runyu Ni, Zhong Ji
{"title":"ICG signal denoising based on ICEEMDAN and PSO-VMD methods.","authors":"Xinhai Li, Runyu Ni, Zhong Ji","doi":"10.1007/s13246-024-01467-0","DOIUrl":"10.1007/s13246-024-01467-0","url":null,"abstract":"<p><p>Impedance cardiography (ICG) plays a crucial role in clinically evaluating cardiac systolic and diastolic functions, along with various other cardiac parameters. However, its accuracy heavily depends on precisely identifying feature points reflecting cardiac function. Moreover, traditional signal processing techniques used to mitigate random noise and breathing artifacts may inadvertently distort the amplitude and temporal characteristics of ICG signals. To address this issue, this study investigates a noise and artifact elimination method based on Improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (ICEEMDAN) and Particle Swarm Optimization-based Variational Mode Decomposition Algorithm (PSO-VMD). The goal is to preserve the amplitude and temporal features of ICG signals to ensure accurate feature point extraction and computation of associated cardiac parameters. Comparative analysis with signal processing methods employing various wavelet families and Ensemble Empirical Mode Decomposition (EEMD) in ICG signal processing applications reveals that the proposed method achieves superior signal-to-noise ratio (SNR) and lower root-mean-square error (RMSE), while demonstrating enhanced correlation and waveform consistency with the original signal.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":"1547-1556"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Load shift keying communication techniques in implantable devices. 植入式设备中的负载移位键控通信技术
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-12-01 Epub Date: 2024-08-19 DOI: 10.1007/s13246-024-01470-5
Francisco Pastene, Martin Westermeyer, Maxime Verstraeten, Adrien Debelle, Vicente Acuña, Antoine Nonclercq, Pablo Aqueveque
{"title":"Load shift keying communication techniques in implantable devices.","authors":"Francisco Pastene, Martin Westermeyer, Maxime Verstraeten, Adrien Debelle, Vicente Acuña, Antoine Nonclercq, Pablo Aqueveque","doi":"10.1007/s13246-024-01470-5","DOIUrl":"10.1007/s13246-024-01470-5","url":null,"abstract":"<p><p>Inductive links represent a highly promising avenue for both powering and communicating medical implants. Yet they encounter challenges such as constrained communication distance and limited data rate. In Load Shift Keying (LSK), a switch in the secondary side of the inductive link can be placed in parallel with the load (Short-Circuit Technique - SCT), in series with the load (Open-Circuit Technique - OCT), or both (Dual Technique - DLT), to vary the impedance of the secondary. Hence, the impedance reflected to the primary side changes and is used to transmit information externally from the implant. Among these, DLT is a novel LSK technique proposed in this work, which becomes independent from the load on the implant side. This study compares these three methods, confronting measurements to simulations. The evaluation focused on variations in coil distance and load. The proposal is illustrated in the case of an implantable gastric stimulator, with specific constraints in secondary coil size and power requirements. The newly developed DLT consistently outshone SCT and OCT in extending the operational range of communication, registering a maximum modulation index of 0.797 and a bit error rate below 10<sup>- 7</sup> at an operating distance of 95 mm through the air. Its load-independent characteristic allowed DLT to surpass the performance of SCT and OCT, which were each advantageous under high and low loads, respectively. All these results are confirmed by a LTSpice simulation. Consequently, the communication techniques put forward in this work mark a significant progression in medical implant communications, enhancing coil-to-coil operational distance while adhering to a low carrier frequency.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":"1557-1570"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A model fusion method based DAT-DenseNet for classification and diagnosis of aortic dissection. 基于 DAT-DenseNet 的主动脉夹层分类和诊断模型融合方法。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-12-01 Epub Date: 2024-09-05 DOI: 10.1007/s13246-024-01466-1
Linlong He, Shuhuan Wang, Ruibo Liu, Tienan Zhou, He Ma, Xiaozeng Wang
{"title":"A model fusion method based DAT-DenseNet for classification and diagnosis of aortic dissection.","authors":"Linlong He, Shuhuan Wang, Ruibo Liu, Tienan Zhou, He Ma, Xiaozeng Wang","doi":"10.1007/s13246-024-01466-1","DOIUrl":"10.1007/s13246-024-01466-1","url":null,"abstract":"<p><p>In this paper, we proposed a complete study method to achieve accurate aortic dissection diagnosis at the patient level. Based on the CT angiography (CTA) images, a classification model named DAT-DenseNet, which combined the deep attention Transformer module with the DenseNet architecture is proposed. In the first phase, two DAT-DenseNet are combined in parallel. It is used to accurately achieve two classification task at the CTA images. In the second stage, we propose a feature fusion module. It concatenates and fuses the image features output from the two classification models on a patient by patient basis. In the comparison experiments of classification model performance, DAT-DenseNet obtained 92.41 <math><mo>%</mo></math> accuracy at the image level, which was 2.20 <math><mo>%</mo></math> higher than the commonly used model. In the comparison experiments of model fusion method, our method obtained 90.83 <math><mo>%</mo></math> accuracy at the patient level. The experiments showed that DAT-DenseNet model exhibits high performance at the image level. Our feature fusion module achieves the mapping from two classification image features to patient outcomes. It achieves accurate patient classification. The experiments' results in the Discussion section elaborate the details of the experiment and confirmed that the results were reliable.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":"1537-1546"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing focal spot alignment in clinical linear accelerators: a comprehensive evaluation with triplet phantoms. 评估临床直线加速器的焦斑对准情况:使用三重模型进行综合评估。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-12-01 Epub Date: 2024-07-02 DOI: 10.1007/s13246-024-01450-9
Hans L Riis, Kenni H Engstrøm, Luke Slama, Joshua Dass, Martin A Ebert, Pejman Rowshanfarzad
{"title":"Assessing focal spot alignment in clinical linear accelerators: a comprehensive evaluation with triplet phantoms.","authors":"Hans L Riis, Kenni H Engstrøm, Luke Slama, Joshua Dass, Martin A Ebert, Pejman Rowshanfarzad","doi":"10.1007/s13246-024-01450-9","DOIUrl":"10.1007/s13246-024-01450-9","url":null,"abstract":"<p><p>A fundamental parameter to evaluate the beam delivery precision and stability on a clinical linear accelerator (linac) is the focal spot position (FSP) measured relative to the collimator axis of the radiation head. The aims of this work were to evaluate comprehensive data on FSP acquired on linacs in clinical use and to establish the ability of alternative phantoms to detect effects on patient plan delivery related to FSP. FSP measurements were conducted using a rigid phantom holding two ball-bearings at two different distances from the radiation source. Images of these ball-bearings were acquired using the electronic portal imaging device (EPID) integrated with each linac. Machine QA was assessed using a radiation head-mounted PTW STARCHECK phantom. Patient plan QA was investigated using the SNC ArcCHECK phantom positioned on the treatment couch, irradiated with VMAT plans across a complete 360° gantry rotation and three X-ray energies. This study covered eight Elekta linacs, including those with 6 MV, 18 MV, and 6 MV flattening-filter-free (FFF) beams. The largest range in the FSP was found for 6 MV FFF. The FSP of one linac, retrofitted with 6 MV FFF, displayed substantial differences in FSP compared to 6 MV FFF beams on other linacs, which all had FSP ranges less than 0.50 mm and 0.25 mm in the lateral and longitudinal directions, respectively. The PTW STARCHECK phantom proved effective in characterising the FSP, while the SNC ArcCHECK measurements could not discern FSP-related features. Minor variations in FSP may be attributed to adjustments in linac parameters, component replacements necessary for beam delivery, and the wear and tear of various linac components, including the magnetron and gun filament. Consideration should be given to the ability of any particular phantom to detect a subsequent impact on the accuracy of patient plan delivery.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":"1361-1383"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of dielectric properties for identification of normal and malignant gastrointestinal tumors and lymph nodes ex vivo. 应用介电特性识别体内正常和恶性胃肠道肿瘤及淋巴结。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-11-26 DOI: 10.1007/s13246-024-01490-1
Xi Rao, Qianyun Chen, Lishan Ding, Noman Shahid, Sidra Wafa, Qiang Huang, Enming Qiu, Xi Zhang, Songsheng Wang, Xueer Xia, Shuai Han, Haijin Chen, Zhou Li
{"title":"Application of dielectric properties for identification of normal and malignant gastrointestinal tumors and lymph nodes ex vivo.","authors":"Xi Rao, Qianyun Chen, Lishan Ding, Noman Shahid, Sidra Wafa, Qiang Huang, Enming Qiu, Xi Zhang, Songsheng Wang, Xueer Xia, Shuai Han, Haijin Chen, Zhou Li","doi":"10.1007/s13246-024-01490-1","DOIUrl":"https://doi.org/10.1007/s13246-024-01490-1","url":null,"abstract":"<p><p>A need exists for a quick, simple method to accurately assess resection margins and lymph node metastases in gastrointestinal cancer surgeries. We aimed to develop a real-time, non-destructive technique to differentiate between normal and cancerous tissues using dielectric properties. Dielectric properties of tissues from 50 gastric and 120 colorectal cancer patients were measured during surgery using an open-ended coaxial probe, spanning frequencies from 10 MHz to 4 GHz. Lymph nodes were classified based on pathology into metastatic and non-metastatic, and tissues were divided into cancerous and normal, the latter being 3 cm from the cancer edge. Statistically significant differences in dielectric properties were found between metastatic and non-metastatic lymph nodes (P < 0.05), and between normal and malignant tissues. Metastatic lymph nodes showed higher dielectric permittivity and conductivity across the frequency range, with no significant difference between gastric and colorectal cancers. The coaxial probe method distinguishes between metastatic and non-metastatic lymph nodes by their dielectric properties within 10-4000 MHz, offering a potential tool for real-time identification of malignant tissues during surgery, despite not identifying the cancer type.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frontal EEG correlation based human emotion identification and classification. 基于额叶脑电图相关性的人类情绪识别与分类。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-11-14 DOI: 10.1007/s13246-024-01495-w
S V Thiruselvam, M Ramasubba Reddy
{"title":"Frontal EEG correlation based human emotion identification and classification.","authors":"S V Thiruselvam, M Ramasubba Reddy","doi":"10.1007/s13246-024-01495-w","DOIUrl":"https://doi.org/10.1007/s13246-024-01495-w","url":null,"abstract":"<p><p>Humans express their feelings and intentions of their actions or communication through emotions. Recent advancements in technology involve machines in human communication in day-to-day life. Thus, understanding of human emotions by machines will be very helpful in assisting the user in a far better way. Various physiological and non-physiological signals can be used to make the machines to recognize the emotion of a person. The identification of emotional content in the signals is crucial to understand emotion and the machines act with emotional intelligence at appropriate times, thus providing a better human machine interaction with emotion identification system and mental health monitoring for psychiatric patients. This work includes the creation of an emotion EEG dataset, the development of an algorithm for identifying the emotion elicitation segments in the EEG signal, and the classification of emotions from EEG signals. The EEG signals are divided into 3s segments, and the segments with emotional content are selected based on the decrease in correlation between the frontal electrodes. The selected segments are validated with the facial expressions of the subjects in the appropriate time segments of the face video. EEGNet is used to classify the emotion from the EEG signal. The classification accuracy with the selected emotional EEG segments is higher compared to the accuracy using all the EEG segments. In subject-specific classification, an average accuracy of 80.87% is obtained from the network trained with selected EEG segments, and 70.5% is obtained from training with all EEG segments. In subject-independent classification, the accuracy of classification is 67% and 63.8% with and without segment selection, respectively. The proposed method of selection of EEG segments is validated using the DEAP dataset, and classification accuracies and F1-scores of subject dependent and subject-independent methods are presented.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Publisher Correction to: Sensitivity improvement of a deuterium-deuterium neutron generator based in vivo neutron activation analysis (IVNAA) system. 出版商更正:基于氘-氘中子发生器的活体中子活化分析(IVNAA)系统的灵敏度改进。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-11-14 DOI: 10.1007/s13246-024-01497-8
Song Yue, Sana Tabbassum, Elizabeth Helen Jaye, Cheryl A M Anderson, Linda H Nie
{"title":"Publisher Correction to: Sensitivity improvement of a deuterium-deuterium neutron generator based in vivo neutron activation analysis (IVNAA) system.","authors":"Song Yue, Sana Tabbassum, Elizabeth Helen Jaye, Cheryl A M Anderson, Linda H Nie","doi":"10.1007/s13246-024-01497-8","DOIUrl":"https://doi.org/10.1007/s13246-024-01497-8","url":null,"abstract":"","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CT scatter spectra transmission data of 80, 100, 120 and 140 kVp primary beams for various shielding materials. 不同屏蔽材料的 80、100、120 和 140 kVp 主光束的 CT 散射光谱传输数据。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-11-13 DOI: 10.1007/s13246-024-01494-x
S M Edwards
{"title":"CT scatter spectra transmission data of 80, 100, 120 and 140 kVp primary beams for various shielding materials.","authors":"S M Edwards","doi":"10.1007/s13246-024-01494-x","DOIUrl":"https://doi.org/10.1007/s13246-024-01494-x","url":null,"abstract":"<p><p>The shielding of computed tomography (CT) suites has commonly relied on the assumption that the primary beam has the same beam quality and thus penetrability as the scattered radiation. This report expands on a preliminary work that showed scattered radiation from patients having an overall reduced beam quality, with published transmission data for 120 kVp and 140 kVp through lead. Beam quality data of patient scatter spectra for 80 kVp and 100 kVp are uniquely provided herein using the same methodology, expanding the diagnostic energy range. The mean energy of scatter radiation spectra across this 80-140 kVp diagnostic range was found to have a reduction of 13.4-17.9% compared to a primary beam with a defined 9.8 mm Al added filtration. A DOSXYZnrc Monte Carlo program using the EGSnrc photon and electron transport code was subsequently used to simulate the transmission of scattered spectra of all 80, 100, 120 and 140 kVp beams through various commonly used shielding materials, including lead, concrete, steel, plate glass and gypsum wallboard. Transmission data and Archer fitting coefficients for this scattered radiation were calculated and show a reduction in transmission over the range of practical shielding thicknesses for these materials. Transmission through lead was significantly reduced in comparison to the National Council of Radiological Protection (NCRP) and British Institute of Radiology (BIR) methodologies using primary beam spectra, with transmissions reduced between 40.4 and 63.9% for 120 kVp and between 38.1 and 42% for 140 kVp beams over a 0.44-2.64 mm thickness range. The use of CT scatter spectra and their resultant transmission data is recommended for optimal shielding design.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement of plan quality in whole-breast radiation following BCS using feasibility DVH by less-experienced planners. 经验不足的计划人员使用可行性 DVH 提高 BCS 后全乳放射计划的质量。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-11-07 DOI: 10.1007/s13246-024-01493-y
Yun Zhang, Yuling Huang, Mingming Luo, Xingxing Yuan, Xiaoping Wang, Changfei Gong
{"title":"Improvement of plan quality in whole-breast radiation following BCS using feasibility DVH by less-experienced planners.","authors":"Yun Zhang, Yuling Huang, Mingming Luo, Xingxing Yuan, Xiaoping Wang, Changfei Gong","doi":"10.1007/s13246-024-01493-y","DOIUrl":"https://doi.org/10.1007/s13246-024-01493-y","url":null,"abstract":"<p><p>Variability in plan quality of radiotherapy is commonly attributed to the planner's skill rather than technological parameters. While experienced planners can set reasonable parameters before optimization, less experienced planners face challenges. This study aimed to assess the quality of volumetric-modulated arc therapy (VMAT) in patients with left-sided breast cancer following breast-conserving surgery. Twenty-eight patients requiring whole-breast irradiation were randomly selected for inclusion. Each patient underwent two VMAT treatment plans: one optimized by an experienced planner (VMAT-EXP group) and the other designed by a less experienced planner using feasibility dose-volume histogram (FDVH) parameters from PlanIQ (VMAT-FDVH group). Both plans aimed to deliver a prescription dose of 50 Gy in 25 fractions to the planning target volume (PTV). Dosimetry parameters for the PTV and organs at risk (OARs) were compared between the two groups. Both the VMAT-EXP and VMAT-FDVH groups met the clinical plan goals for PTV and OARs. VMAT-FDVH demonstrated a PTV coverage and homogeneity comparable to those of VMAT-EXP. Compared to VMAT-EXP plans, VMAT-FDVH plans resulted in a significant reduction in the mean ipsilateral lung dose, with an average decrease of 0.9 Gy (8.5 Gy vs. 7.6 Gy, P < 0.001). The V5Gy and V20Gy of the ipsilateral lung were also reduced by 3.2% and 1.8%, respectively. Minor differences were observed in the heart, contralateral lung, breast, and liver. Personalized objectives derived from the feasibility DVH tool facilitated the generation of acceptable VMAT plans. Less experienced planners achieved lower doses to the ipsilateral lung while maintaining adequate target coverage and homogeneity. These findings suggest the potential for the effective use of VMAT in in patients with left-sided breast cancer following breast-conserving surgery, especially when guided by feasibility DVH parameters.</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re-evaluation of 18 F-FDG absorbed and effective dose in adult and pediatric phantoms using DoseCalcs Monte Carlo platform: a validation study. 使用 DoseCalcs Monte Carlo 平台重新评估成人和儿童模型中 18 F-FDG 的吸收和有效剂量:一项验证研究。
IF 2.4 4区 医学
Physical and Engineering Sciences in Medicine Pub Date : 2024-11-05 DOI: 10.1007/s13246-024-01492-z
Tarik El Ghalbzouri, Tarek El Bardouni, Jaafar El Bakkali, Otman El Hajjaji, Hicham Satti, Assia Arectout, Maryam Hadouachi, Randa Yerru
{"title":"<ArticleTitle xmlns:ns0=\"http://www.w3.org/1998/Math/MathML\">Re-evaluation of <ns0:math><ns0:mmultiscripts><ns0:mrow /> <ns0:mrow /> <ns0:mn>18</ns0:mn></ns0:mmultiscripts> </ns0:math> F-FDG absorbed and effective dose in adult and pediatric phantoms using DoseCalcs Monte Carlo platform: a validation study.","authors":"Tarik El Ghalbzouri, Tarek El Bardouni, Jaafar El Bakkali, Otman El Hajjaji, Hicham Satti, Assia Arectout, Maryam Hadouachi, Randa Yerru","doi":"10.1007/s13246-024-01492-z","DOIUrl":"https://doi.org/10.1007/s13246-024-01492-z","url":null,"abstract":"<p><p>Positron emission tomography (PET) using <math><mmultiscripts><mrow></mrow> <mrow></mrow> <mn>18</mn></mmultiscripts> </math> F-FDG is a well-known modality for the diagnosis of various diseases in patients of different ages, sexes, and states of health, which implies that internal radiation dosimetry is highly desired for different phantom anatomies. In this study, we validate \"DoseCalcs,\" a new Monte Carlo platform that combines personalized internal dosimetry calculations with Monte Carlo simulations. To achieve that, we used the specific absorbed fraction (SAF) calculated by DoseCalcs and those from ICRP publication 133 to estimate the absorbed dose per injected activity (AD/IA) and effective dose per injected activity (ED/IA) for <math><mmultiscripts><mrow></mrow> <mrow></mrow> <mn>18</mn></mmultiscripts> </math> F-FDG. The investigation focused on various voxelized phantoms representing different age groups, including adult male and female, and pediatric phantoms of various ages, from newborn to 15 years old. Using the DoseCalcs Monte Carlo platform, we have simulated the emission of <math><mmultiscripts><mrow></mrow> <mrow></mrow> <mn>18</mn></mmultiscripts> </math> F-FDG positrons based on the energy spectrum provided in ICRP publication 107. The results demonstrated the impact of anatomical differences and different organ/tissue compositions on radiation absorption, with significant variations in the AD/IA across different phantoms. Interestingly, organs/tissues near the emission source showed higher AD/IA, highlighting the anatomical dependence on the phantom. When our results were compared to established reference data, especially from ICRP128, most organs/tissues had good agreement. Still, some cases have shown differences. This shows how important it is to use accurate radionuclide data and biokinetic modeling in internal dosimetry calculations. Furthermore, we compared AD/IA and ED/IA values calculated in newborns by DoseCalcs with those derived from alternative codes, MCNP and EGSnrc. While the results generally exhibited consistency, subtle variations underscored the influence of biokinetics modeling choices and computational methodologies. Overall, this research contributes valuable insights into the precision of internal dosimetry calculations using \"DoseCalcs-Gui\" by providing one platform for Monte Carlo simulation and personalized internal dosimetry in nuclear medicine. The DoseCalcs platform is free for research and available for download at www.github.com/TarikEl/DoseCalcs-Gui .</p>","PeriodicalId":48490,"journal":{"name":"Physical and Engineering Sciences in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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