Clinical Psychology Review最新文献

{"title":"Do metacognitive beliefs satisfy criteria as mechanisms of change in treatment? A systematic review and evidence synthesis","authors":"Erlend Pukstad ,&nbsp;Joar Øveraas Halvorsen ,&nbsp;Magnus Rom Jensen ,&nbsp;Solvor Solhaug ,&nbsp;Henrik Nordahl","doi":"10.1016/j.cpr.2025.102654","DOIUrl":"10.1016/j.cpr.2025.102654","url":null,"abstract":"<div><div>The Self-Regulatory Executive Function (S-REF) model emphasizes biases in metacognition, and particularly negative metacognitive beliefs, as the central mechanism of persistent emotional distress and disorders. Hence, interventions which effectively modify dysfunctional metacognitions are predicted to create improvement regardless of whether metacognitions are directly targeted or not. With an aim to evaluate the empirical support for metacognitions as a mechanism of change in psychopathology, we conducted a systematic review of the literature focusing on metacognitive change and its relationship to change in outcomes across emotional disorders and therapeutic interventions. Systematic searches were conducted and following PRISMA 2020 guidelines, 27 articles were identified. Results were synthesized and evaluated against established criteria for accurately classifying theoretical predictors as mechanisms of change. Our review shows a consistent association between change in metacognitions, particularly negative metacognitive beliefs, and outcome changes across different mental disorders, outcomes, and interventions. This relationship held even when controlling competing mechanisms such as cognitive beliefs and support the criterion of specificity. However, most of the identified studies lacked the methodological rigor needed (e.g., multiple assessment points during the treatment phase) to draw firm conclusions about metacognitions as a causal mechanism of change. Based on the existing literature, we conclude that metacognition is promising as a candidate to be considered a transdiagnostic mechanism of change of emotional disorders. We provide directions for future research necessary to more definitely determine the role of metacognitive change in psychopathology improvement and recovery.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102654"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to Jumping to conclusions and delusional ideation: A systematic review and meta-analysis across the psychosis continuum [Clinical Psychology Review 120 (2025) 102618]","authors":"Rose Doherty ,&nbsp;Nathan Weber ,&nbsp;Charley Hillier ,&nbsp;Robert Ross ,&nbsp;Ryan Balzan","doi":"10.1016/j.cpr.2025.102670","DOIUrl":"10.1016/j.cpr.2025.102670","url":null,"abstract":"","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102670"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145507587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gamified interventions for schizophrenia rehabilitation: A systematic scoping review","authors":"Hongyi Yang ,&nbsp;Fangyuan Chang ,&nbsp;Dian Zhu ,&nbsp;Muroi Fumie ,&nbsp;Zhao Liu ,&nbsp;Weibo Zhang ,&nbsp;Jun Cai","doi":"10.1016/j.cpr.2025.102651","DOIUrl":"10.1016/j.cpr.2025.102651","url":null,"abstract":"<div><div>Schizophrenia affects 24 million people worldwide, yet standard rehabilitation remains resource-intensive and its effectiveness inconsistent. To clarify whether game-based approaches can close these gaps, we reviewed studies published between January 2014–June 2025 in PubMed, Web of Science, PsycINFO and the ACM Digital Library. Eighty-two studies comprising about 5800 unique participants met the predefined eligibility criteria and were qualitatively synthesized. Interventions fell into three partially overlapping groups: serious games (<em>n</em> = 38), gamified applications (<em>n</em> = 20), and commercial games (<em>n</em> = 29). Outcomes were clustered into six domains—cognitive function, social function, symptom management, motor function, lifestyle management, and self-efficacy—and benefits proved to be domain- and modality-specific. Virtual reality-based serious games yielded the largest gains in social cognition (Cohen's d = 0.26–1.66). Gamified applications produced moderate-to-large improvements in negative symptoms (d ≈ 0.75–0.90) and achieved the highest engagement indices. Commercial games delivered small-to-moderate enhancements in motor fitness and social functioning (d ≈ 0.22–0.80). Evidence quality remains limited, as only 45 controlled trials were randomized; 12 enrolled at least 100 participants; 10 tracked outcomes beyond three months; only one achieved a low risk-of-bias rating, more than 90 % originated in high-income countries, and fewer than one-third articulated a theoretical framework. The data generally support gamified interventions as promising adjunctive tools rather than standalone replacements for conventional care. Multi-site randomized trials with ≥12-month follow-ups and harmonized core outcome sets, mechanism-driven optimizations that isolate active game mechanics, and cost-effectiveness plus equity analyses are necessary.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102651"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding dropout during psychological treatment for gambling: A scoping review","authors":"C.O. Hawker ,&nbsp;S.E. Dias ,&nbsp;N.A. Dowling ,&nbsp;A.C. Thomas ,&nbsp;B.J. Thornley ,&nbsp;S.L. Campbell ,&nbsp;K.L. Quigley ,&nbsp;S.S. Merkouris","doi":"10.1016/j.cpr.2025.102653","DOIUrl":"10.1016/j.cpr.2025.102653","url":null,"abstract":"<div><h3>Abstract</h3><div>This scoping review broadly aims to identify recent research on six indices of dropout during face-to-face psychological treatment for harmful gambling, including definitions of dropout, estimates of dropout, reasons for dropout, predictors of dropout, consequences of dropout, and solutions to dropout. A systematic search of electronic databases and grey literature identified 66 studies (from 67 articles/reports) published from 2004, most commonly contributing data to estimates (94 %), followed by predictors (74 %), definitions (73 %), reasons (15 %), consequences (8 %), and solutions (3 %). The findings revealed several definitions of dropout, typically relating to the non-attendance of a pre-defined and usually arbitrary number of treatment sessions, which risks the misclassification of clients with symptom improvement. The median rate of dropout (derived from 76 estimates) was 35.4 % across all treatment types and 34.8 % across Cognitive Behavioural Therapy (CBT) treatments. The most reported reasons for dropout were practical issues (e.g., scheduling conflicts), with few reasons relating to specific therapeutic orientations recorded. A large number of potential predictors have been examined with few consistent results, whereby being married/de-facto appears to consistently lower the risk of dropout. Dropout was consistently associated with higher subsequent gambling symptoms, urges, cognitions, and behaviors, with some additional evidence for worsened psychological symptoms, albeit based on a small number of studies. Only two studies examined the addition of motivational procedures to redress the risk of dropout, which produced favourable results. More research is needed, utilising standardised definitions and bespoke large-scale examinations, to improve retention during gambling treatment.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102653"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To disclose or not to disclose: A systematic review of factors associated with disclosure and concealment of mental illnesses","authors":"Miri Gnainsky ,&nbsp;David Roe ,&nbsp;Ofir Negri-Schwartz ,&nbsp;Yael Cohen-Chazani ,&nbsp;Michal Lavidor ,&nbsp;Ilanit Hasson-Ohayon","doi":"10.1016/j.cpr.2025.102660","DOIUrl":"10.1016/j.cpr.2025.102660","url":null,"abstract":"<div><div>The decision to disclose or conceal a mental illness represents a complex dilemma influenced by various personal, social, and environmental factors. Through a systematic review of 42 quantitative studies published until May 2025, we examined how individuals manage mental illness disclosure and secrecy, and their associations with mental health outcomes, perception-related variables, and functional outcomes. Findings show that secrecy had consistent negative associations with mental health outcomes including depression, well-being, and quality of life, while disclosure's associations with outcomes varied across different contexts. Second, self-perception-related variables, particularly stigma, played a central role – with studies showing different patterns of associations between disclosure and both self-stigma and public stigma. Third, selective disclosure emerged as a strategy for managing disclosure processes across different social contexts. In employment settings, mixed findings emerged regarding disclosure outcomes, with some studies showing associations with job matching and duration, although these varied by workplace context. Several factors that influenced the observed associations were identified, including perceived social support and contextual factors. Notably, disclosure and secrecy operated as distinct rather than opposite processes, with individuals often managing both simultaneously across different contexts. These findings highlight the need for nuanced approaches to supporting disclosure decisions, considering both personal and environmental factors in clinical practice and organizational interventions.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102660"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic stress disorder symptoms and suicide ideation, attempt, and risk among active-duty service members and veterans: A systematic review with three meta-analyses of associations and moderators","authors":"David P. Cenkner,&nbsp;Amy L. Dent,&nbsp;Agnes Zhou,&nbsp;Katherine E. Wislocki,&nbsp;Sarah K. Stevens,&nbsp;Sono Lee,&nbsp;Kayvon Amindari,&nbsp;Matt Sereno,&nbsp;Daniel Lu,&nbsp;Megan Chang,&nbsp;Hanniel Uwadia,&nbsp;Ethan G. Smith,&nbsp;Riley Woo,&nbsp;Hana Nip,&nbsp;Bethzaida N. Serrano,&nbsp;Alyson K. Zalta","doi":"10.1016/j.cpr.2025.102652","DOIUrl":"10.1016/j.cpr.2025.102652","url":null,"abstract":"<div><div>Posttraumatic stress disorder (PTSD) is an established risk factor for suicidality in service members and veterans (SM/Vs). However, no meta-analysis has examined associations between PTSD symptom severity and suicidality in SM/Vs or moderators of these relationships. Three meta-analyses examined cross-sectional correlations between PTSD symptoms and suicide ideation, attempt, and risk. Seven databases were searched four times, most recently in June 2025. Eligible reports had to include adult SM/Vs, be written in English, be published in or after 1980, assess PTSD symptoms, and include a validated measure of suicidal ideation, attempts, or risk (or single item of attempts). We included 87 ideation effect sizes representing 82,318 SM/Vs, 74 attempt effect sizes representing 104,952 SM/Vs, and 45 risk effect sizes representing 38,927 SM/Vs. Correlated-and-hierarchical effects models with robust variance estimation revealed significant summary correlations for ideation (<em>r</em>_<em>z</em> = 0.29; 95 % PI [0.02, 0.57]), attempt (<em>r</em>_<em>z</em> = 0.16; 95 % PI [0.003, 0.32]), and risk (<em>r</em>_<em>z</em> = 0.40; 95 % PI [0.08, 0.72]), all with statistically significant heterogeneity. Among 19 moderators tested, veteran status (v. active-duty) significantly strengthened the correlation with suicidal ideation (<em>b</em> = 0.12, <em>se</em> = 0.04, <em>t</em>(34.03) = 2.91, <em>p</em> = .006) and suicide attempt (<em>b</em> = 0.08, <em>se</em> = 0.03, <em>t</em>(19.83) = 2.44, <em>p</em> = .024). Partnered status significantly strengthened the correlation with suicide risk (<em>b</em> = 0.01, <em>se</em> = 0.00, <em>t</em>(8.77) = 4.62, <em>p</em> = .001). Findings highlight who might be at greater risk for suicide and underscore the potential benefits of treating PTSD symptoms for suicide prevention in SM/Vs.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102652"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic stress disorder and climate change: A meta-analysis of prospective, acute predictors of PTSD following extreme weather events","authors":"Gabrielle M. Gauthier,&nbsp;Shivani Pandey,&nbsp;Victoria Sanchez,&nbsp;Savanna E. Stromberg,&nbsp;Lori A. Zoellner","doi":"10.1016/j.cpr.2025.102662","DOIUrl":"10.1016/j.cpr.2025.102662","url":null,"abstract":"<div><h3>Objective</h3><div>Extreme weather events are increasing in intensity and frequency due to climate change. Better understanding key prospective predictors of chronic posttraumatic stress disorder (PTSD) present in the acute wake of a disaster is essential to allocating limited resources to those at greatest risk. Additionally, identifying prospective predictors of PTSD may help elucidate etiological factors that could be harnessed for psychological interventions to prevent chronic PTSD.</div></div><div><h3>Method</h3><div>PubMed, PsycInfo and PTSDPubs were systematically searched in February 2025 for longitudinal studies prospectively examining PTSD in adults following extreme weather events (e.g., hurricanes) with at least one pre-disaster or acutely post-disaster (&lt; 18 months) timepoint. Effect sizes of demographic (e.g., gender), pre-event (e.g., pre-disaster psychopathology), and environmental factors (e.g., social support) were extracted and synthesized as correlations using random effects modeling.</div></div><div><h3>Results</h3><div>Forty-seven unique samples (<em>N</em> = 25,085) were included, with a majority collected in North America (63.83 %). The most frequent disaster type was hurricanes/typhoons (53.19 %). Severity of disaster exposure (<em>r</em> = 0.26), income (<em>r</em> = −0.26), and prior psychopathology (<em>r</em> = 0.26) emerged as the strongest predictors of PTSD.</div></div><div><h3>Conclusions</h3><div>This is the first meta-analysis to examine prospective predictors of PTSD following extreme weather events collectively. The small- to moderate-sized effects observed suggest that predictors likely operate cumulatively to confer risk. Relative to other trauma types, access to resources, such as higher income, may be an important buffer against mental health problems. Future work should investigate modifiable predictors of PTSD that could potentially be harnessed in early interventions.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102662"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associated factors of the quality of therapeutic alliance in people with severe mental illnesses: A systematic review","authors":"Melina Tetzlaff ,&nbsp;Jojanneke Bruins ,&nbsp;Stynke Castelein","doi":"10.1016/j.cpr.2025.102656","DOIUrl":"10.1016/j.cpr.2025.102656","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite the recognized importance of the therapeutic alliance (TA) in mental health care for people with severe mental illness (SMI), research examining factors associated with the quality of the TA remains limited.</div></div><div><h3>Objectives</h3><div>This review systematically synthesizes literature on factors associated with TA across six domains: client, mental health professional (MHP), clinical, social, care, and other factors. TA ratings from clients, MHPs, and independent observers are included.</div></div><div><h3>Methods</h3><div>Parallel literature searches in PsycInfo, Medline, and PubMed between 2000-June 2025 identified 5198 potential articles, of which 48 met inclusion.</div></div><div><h3>Results</h3><div>Factors associated with better client-rated TA included better illness-insight, client secure attachment style, positive outcome expectancy, less stigma, use of supportive techniques during therapy, early positive connections, and specific MHP characteristics. For MHP-rated, better outcomes were linked to better client insight, MHP attachment style, early positive connections, and less severe client symptomatology.</div></div><div><h3>Discussion</h3><div>Clinical symptom severity influenced MHP-rated TA, but not client-rated TA. A secure attachment of the client favored TA quality, while other attachment styles appeared to be unrelated to TA. Early positive interactions between client and MHP establish a foundation for later stable TA. Creating a warm, supportive environment helps clients overcome stigma and develop positive outcome expectations. Emphasizing supportive techniques such as providing feedback and shared agenda-setting, rather than focusing solely on the clients' symptomatology, may enhance TA perception. Future TA research may benefit from understanding the interplay between client and MHP-related contributions to the alliance, thereby incorporating the multidisciplinary nature of MHPs involved in SMI treatment.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102656"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145311768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review and meta-analysis examining the effect of obsessive-compulsive disorder on associative learning","authors":"Liam Alexander MacKenzie Myles ,&nbsp;Matthew Hotton ,&nbsp;Francis Madden ,&nbsp;Paul M. Salkovskis","doi":"10.1016/j.cpr.2025.102661","DOIUrl":"10.1016/j.cpr.2025.102661","url":null,"abstract":"<div><h3>Background</h3><div>This systematic review and meta-analysis evaluated whether people with obsessive-compulsive disorder (OCD) exhibit differences in associative learning.</div></div><div><h3>Methods</h3><div>CINAHL, Cochrane Library, EMBASE, PsycINFO, PubMed, Scopus and Web of Science were searched for published peer-reviewed studies in English quantitatively examining the relationship between OCD and associative phenomena in humans. 5508 titles, 124 abstracts and 55 full texts were reviewed; citation searching identified 15 records. Sixty-six studies were included. Risk of bias was assessed and random-effects meta-analysis synthesised results.</div></div><div><h3>Results</h3><div>Obsessive-compulsive disorder was associated with differences in extinction (g = 0.37, <em>p</em> &lt; .001, k = 15) and mediated associative learning (k = 1), but not associative learning (g = −0.12, <em>p</em> = .26, k = 49), avoidance learning (g = 1.5, <em>p</em> = .13, k = 4), blocking (k = 1), generalisation (g = −0.2, <em>p</em> = .16, k = 3), latent inhibition (g = 0.45, <em>p</em> = .39, k = 3), outcome devaluation (g = 0.26, <em>p</em> = .33, k = 7), Pavlovian-to-instrumental transfer (g = −0.24, <em>p</em> = .22, k = 2) or reversal learning (g = 0.16, <em>p</em> = .36, k = 10). The quality of evidence was moderate for reversal learning, low for associative learning, extinction, generalisation, latent inhibition and Pavlovian-to-instrumental transfer, and very low for avoidance learning and outcome devaluation.</div></div><div><h3>Conclusion</h3><div>Low quality evidence suggests people with OCD learn that stimuli no longer predict negatively valanced outcomes slower than healthy controls. Future research must elucidate the cause of attenuated extinction and its specificity to OCD.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102661"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145412323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Substance use disorder and altered hemispheric asymmetries: A systematic review","authors":"Annakarina Mundorf ,&nbsp;Hicret Atilgan ,&nbsp;Lisa Deneke ,&nbsp;Sebastian Ocklenburg","doi":"10.1016/j.cpr.2025.102658","DOIUrl":"10.1016/j.cpr.2025.102658","url":null,"abstract":"<div><div>Substance use disorder (SUD) is characterized by compulsive use despite adverse consequences and may be influenced by brain asymmetry affecting cognitive and emotional processes. This systematic review investigates the relationship between brain asymmetry and SUD. PubMed, Web of Science, and PsycInfo were searched for articles published until July 2025, using the search terms: ((Alcoholism) OR (alcohol abuse) OR (substance abuse) OR (addiction)) AND ((handedness) OR (footedness) OR (dichotic listening) OR (line bisection task) OR (visual half field technique) OR (fMRI asymmetry) OR (EEG asymmetry) OR (structural asymmetry)). Inclusion criteria were (i) subjects having a diagnosis of or meeting the criteria for alcoholism, alcohol abuse, substance abuse, or addiction assessed with a validated clinical inventory, (ii) articles must contain information on handedness, footedness, dichotic listening, line bisection task, the visual half-field technique, or hemispheric differences (iii) data must be given for the clinical group separately, (iv) original research article in the English language. For neuroimaging studies, both hemispheres needed to be examined separately. Exclusion criteria included: (i) review articles; (ii) studies without matched groups; (iii) studies on recreational use only; (iv) those involving prenatal substance exposure or comorbid neurological disorders. Risk of bias was assessed with the Newcastle-Ottawa Scale. Forty-nine studies met the criteria. Structural imaging indicates asymmetric white and grey matter alterations: reduced left-hemispheric white matter integrity and lower grey matter volume in frontal and temporal regions. Functional data show compensatory right-hemispheric activation. Behavioral lateralization findings vary by substance type, sex, and age, with potential implications for personalized treatment strategies.</div></div>","PeriodicalId":48458,"journal":{"name":"Clinical Psychology Review","volume":"122 ","pages":"Article 102658"},"PeriodicalIF":12.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145261567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}