Journal of Anxiety Disorders最新文献_第2页

Safety behaviors and positive emotions in social anxiety disorder 社交焦虑症患者的安全行为和积极情绪

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-16 DOI: 10.1016/j.janxdis.2024.102915

引用次数: 0

Neuromodulation treatments for post-traumatic stress disorder: A systematic review and network meta-analysis covering efficacy, acceptability, and follow-up effects 创伤后应激障碍的神经调节疗法：涵盖疗效、可接受性和随访效果的系统综述和网络荟萃分析

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102912

{"title":"Neuromodulation treatments for post-traumatic stress disorder: A systematic review and network meta-analysis covering efficacy, acceptability, and follow-up effects","authors":"","doi":"10.1016/j.janxdis.2024.102912","DOIUrl":"10.1016/j.janxdis.2024.102912","url":null,"abstract":"<div><p>Neuromodulation treatments are novel interventions for post-traumatic stress disorder (PTSD), but their comparative effects at treatment endpoint and follow-up and the influence of moderators remain unclear. We included randomized controlled trials (RCTs) that explored neuromodulation, both as monotherapy and in combination, for treating patients with PTSD. 21 RCTs with 981 PTSD patients were included. The neuromodulation treatment was classified into nine protocols, including subtypes of transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), cervical vagal nerve stimulation (VNS), and trigeminal nerve stimulation (TNS). This Bayesian network meta-analysis demonstrated that (1) dual-tDCS (SMD = −1.30), high-frequency repetitive TMS (HF-rTMS) (SMD = −0.97), intermittent theta burst stimulation (iTBS) (SMD = −0.93), and low-frequency repetitive TMS (LF-rTMS) (SMD = −0.76) were associated with significant reductions in PTSD symptoms at the treatment endpoint, but these effects were not significant at follow-up; (2) no difference was found between any active treatment with sham controls; (3) regarding co-morbid additions, synchronized TMS (sTMS) was significantly associated with reductions of depression symptoms at treatment endpoint (SMD = −1.80) and dual-tDCS was associated with reductions in anxiety symptoms at follow-up (SMD = −1.70). Findings suggested dual-tDCS, HF-rTMS, iTBS, and LF-rTMS were effective for reducing PTSD symptoms, while their sustained efficacy was limited.</p></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Daily-life reactivity and emotion regulation in children with social anxiety disorder 社交焦虑症儿童的日常生活反应能力和情绪调节能力。

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102907

{"title":"Daily-life reactivity and emotion regulation in children with social anxiety disorder","authors":"","doi":"10.1016/j.janxdis.2024.102907","DOIUrl":"10.1016/j.janxdis.2024.102907","url":null,"abstract":"<div><p>Prominent models of adult social anxiety disorder emphasize the role of hyperreactivity and emotion regulation (ER) difficulties. However, it is unclear whether these factors are relevant in childhood, a critical period for the development of this disorder. We used ecological momentary assessment with mobile phones to assess daily-life emotional reactivity and use and effectiveness of ER strategies in children aged 10–13 years. We compared three groups: Social anxiety disorder (<em>n</em> = 29), clinical controls with mixed anxiety disorders (<em>n</em> = 27) and healthy controls (<em>n</em> = 31). We also investigated long-term effects of ER on trait social anxiety 12 months later. Hierarchical linear modelling revealed higher emotional reactivity and more use of suppression in children with social anxiety disorder compared to clinical and healthy controls. Contrary to our expectations, children with social anxiety disorder reported more use of avoidance and reappraisal compared to clinical, but not healthy, controls. The groups did not differ in subjective effectiveness of ER strategies. Use of suppression, avoidance, and rumination each predicted an increase in social anxiety 12 months later. Taken together, our results extend previous findings from lab and questionnaire studies and illustrate the role of maladaptive ER for child social anxiety disorder.</p></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0887618524000835/pdfft?md5=a0921cbf850cbcabc5d5aaa4a5ce8ae1&pid=1-s2.0-S0887618524000835-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicians’ perspectives on retraumatisation during trauma-focused interventions for post-traumatic stress disorder: A survey of UK mental health professionals 临床医生在对创伤后应激障碍进行以创伤为重点的干预过程中对再创伤化的看法：英国心理健康专业人员调查。

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102913

{"title":"Clinicians’ perspectives on retraumatisation during trauma-focused interventions for post-traumatic stress disorder: A survey of UK mental health professionals","authors":"","doi":"10.1016/j.janxdis.2024.102913","DOIUrl":"10.1016/j.janxdis.2024.102913","url":null,"abstract":"<div><p>Concerns regarding retraumatisation have been identified as a barrier to delivering trauma-focused therapy for post-traumatic stress disorder (PTSD). We explored clinicians’ understanding of what constitutes potential signs of retraumatisation (PSoR), reported incidences of witnessing retraumatisation, use of (and confidence in) therapies for PTSD, fear of retraumatisation during therapy for PTSD, and whether having witnessed retraumatisation was associated with these variables. We surveyed 348 clinicians. There was variation in what clinicians viewed as PSoR. Retraumatisation was reported by clinicians in 3.4 % of patients undergoing trauma-focused therapy for PTSD. A variety of trauma-focused and non-trauma-focused therapies were routinely used, yet 14.4 % reported not using trauma-focused therapy. There was a significant negative correlation between participants’ highest reported confidence in trauma-focused therapy and endorsement of PSoR (<em>r</em> = −.25) and fear of retraumatisation (<em>r</em> = −.28). Mean fear of retraumatisation was 30.3 (<em>SD</em>=23.4; a score we derived from asking participants out of 100 how much they worry about trauma-focused therapy being harmful in its own right/leading to a worsening of PTSD symptoms). Participants who had witnessed retraumatisation reported significantly greater endorsement of PSoR (<em>d</em>=.69 [95 % CI .37, 1.02]) and fear of retraumatisation (<em>d</em>=.94 [95 % CI .61, 1.26]). Confidence in using therapies for PTSD was varied and related to how clinicians understood retraumatisation. Retraumatisation is uncommon, but there is variability in clinicians’ interpretation of what retraumatisation is, and its utility warrants research.</p></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0887618524000896/pdfft?md5=a3686b30d33aa1660792f91227aa9b61&pid=1-s2.0-S0887618524000896-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Network analyses of ecological momentary emotion and avoidance assessments before and after cognitive behavioral therapy for anxiety disorders 焦虑症认知行为疗法前后的生态瞬间情绪和回避评估网络分析

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102914

{"title":"Network analyses of ecological momentary emotion and avoidance assessments before and after cognitive behavioral therapy for anxiety disorders","authors":"","doi":"10.1016/j.janxdis.2024.102914","DOIUrl":"10.1016/j.janxdis.2024.102914","url":null,"abstract":"<div><p>Negative emotions and associated avoidance behaviors are core symptoms of anxiety. Current treatments aim to resolve dysfunctional coupling between them. However, precise interactions between emotions and avoidance in patients’ everyday lives and changes from pre- to post-treatment remain unclear. We analyzed data from a randomized controlled trial where patients with anxiety disorders underwent 16 sessions of cognitive behavioral therapy (CBT). Fifty-six patients (68 % female, age: <em>M</em> = 33.31, <em>SD</em> = 12.45) completed ecological momentary assessments five times a day on 14 consecutive days before and after treatment, rating negative emotions and avoidance behaviors experienced within the past 30 min. We computed multilevel vector autoregressive models to investigate contemporaneous and time-lagged associations between anxiety, depression, anger, and avoidance behaviors within patients, separately at pre- and post-treatment. We examined pre-post changes in network density and avoidance centrality, and related these metrics to changes in symptom severity. Network density significantly decreased from pre- to post-treatment, indicating that after therapy, mutual interactions between negative emotions and avoidance were attenuated. Specifically, contemporaneous associations between anxiety and avoidance observed before CBT were no longer significant at post-treatment. Effects of negative emotions on avoidance assessed at a later time point (avoidance instrength) decreased, but not significantly. Reduction in avoidance instrength positively correlated with reduction in depressive symptom severity, meaning that as patients improved, they were less likely to avoid situations after experiencing negative emotions. Our results elucidate mechanisms of successful CBT observed in patients’ daily lives and may help improve and personalize CBT to increase its effectiveness.</p></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0887618524000902/pdfft?md5=2db0296c6973bea219b5dbb8564d5d8e&pid=1-s2.0-S0887618524000902-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141993469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reward processes in extinction learning and applications to exposure therapy 消退学习中的奖励过程及其在暴露疗法中的应用。

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102911

引用次数: 0

Predicting treatment outcomes in patients with panic disorder: Cross-sectional and two-year longitudinal structural connectome analysis using machine learning methods 预测惊恐障碍患者的治疗效果：使用机器学习方法进行横截面和两年纵向结构连接组分析

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102895

{"title":"Predicting treatment outcomes in patients with panic disorder: Cross-sectional and two-year longitudinal structural connectome analysis using machine learning methods","authors":"","doi":"10.1016/j.janxdis.2024.102895","DOIUrl":"10.1016/j.janxdis.2024.102895","url":null,"abstract":"<div><h3>Purpose</h3><p>This study examined the relationship between structural brain networks and long-term treatment outcomes in patients with panic disorder (PD) using machine learning methods.</p></div><div><h3>Method</h3><p>The study involved 80 participants (53 PD patients and 27 healthy controls) and included clinical assessments and MRI scans at baseline and after two years (160 MRIs). Patients were categorized based on their response to two-year pharmacotherapy. Brain networks were analyzed using white matter tractography and network-based statistics.</p></div><div><h3>Results</h3><p>Results showed structural network changes in PD patients, particularly in the extended fear network, including frontal regions, thalamus, and cingulate gyrus. Longitudinal analysis revealed that increased connections to the amygdala, hippocampus, and insula were associated with better treatment response. Conversely, overconnectivity in the amygdala and insula at baseline was associated with poor response, and similar patterns were found in the insula and parieto-occipital cortex related to non-remission. This study found that SVM and CPM could effectively predict treatment outcomes based on network pattern changes in PD.</p></div><div><h3>Conclusions</h3><p>These findings suggest that monitoring structural connectome changes in limbic and paralimbic regions is critical for understanding PD and tailoring treatment. The study highlights the potential of using personalized biomarkers to develop individualized treatment strategies for PD.</p></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intolerance of uncertainty as a predictor of anxiety severity and trajectory during the COVID-19 pandemic 对不确定性的不容忍度是 COVID-19 大流行期间焦虑严重程度和发展轨迹的预测因素。

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102910

{"title":"Intolerance of uncertainty as a predictor of anxiety severity and trajectory during the COVID-19 pandemic","authors":"","doi":"10.1016/j.janxdis.2024.102910","DOIUrl":"10.1016/j.janxdis.2024.102910","url":null,"abstract":"<div><h3>Background</h3><p>Efforts to identify risk and resilience factors for anxiety severity and course during the COVID-19 pandemic have focused primarily on demographic rather than psychological variables. Intolerance of uncertainty (IU), a transdiagnostic risk factor for anxiety, may be a particularly relevant vulnerability factor.</p></div><div><h3>Method</h3><p><em>N</em> = 641 adults with pre-pandemic anxiety data reported their anxiety, IU, and other pandemic and mental health-related variables at least once and up to four times during the COVID-19 pandemic, with assessments beginning in May 2020 through March 2021.</p></div><div><h3>Results</h3><p>In preregistered analyses using latent growth models, higher IU at the first pandemic timepoint predicted more severe anxiety, but also a sharper decline in anxiety, across timepoints. This finding was robust to the addition of pre-pandemic anxiety and demographic predictors as covariates (in the full sample) as well as pre-pandemic depression severity (in participants for whom pre-pandemic depression data were available). Younger age, lower self/parent education, and self-reported history of COVID-19 illness at the first pandemic timepoint predicted more severe anxiety across timepoints with strong model fit, but did not predict anxiety trajectory.</p></div><div><h3>Conclusions</h3><p>IU prospectively predicted more severe anxiety but a sharper decrease in anxiety over time during the pandemic, including after adjustment for covariates. IU therefore appears to have unique and specific predictive utility with respect to anxiety in the context of the COVID-19 pandemic.</p></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scaling up psychological interventions into the daily lives of patients with anxiety and related disorders 将心理干预措施推广到焦虑症及相关疾病患者的日常生活中

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102916

引用次数: 0

Correlates of treatment-seeking in DSM-5 generalized anxiety disorder: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions‐III DSM-5 广泛性焦虑症患者寻求治疗的相关因素：全国酒精及相关疾病流行病学调查-III》的研究结果。

IF 4.8 2区医学

Journal of Anxiety Disorders Pub Date : 2024-08-01 DOI: 10.1016/j.janxdis.2024.102909

{"title":"Correlates of treatment-seeking in DSM-5 generalized anxiety disorder: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions‐III","authors":"","doi":"10.1016/j.janxdis.2024.102909","DOIUrl":"10.1016/j.janxdis.2024.102909","url":null,"abstract":"<div><p>Generalized Anxiety Disorder (GAD) presents a significant personal and societal burden and is associated with chronic medical comorbidities and markedly lower quality of life. Effective treatments exist, less than half of individuals with lifetime GAD will ever seek psychotherapeutic or pharmacological treatment. A thorough understanding of the factors that influence treatment seeking for GAD is warranted. The present study investigates the correlates of GAD treatment seeking, using data from the National Epidemiological Survey on Alcohol and Related Disorders-III (NESARC-III), which assessed for psychiatric disorders using the Alcohol Use Disorder and Associated Disabilities Interview Schedule-DSM-5 Version (AUDADIS-5). A series of logistic regressions were run to identify demographic, diagnostic, and symptom-level correlates of treatment seeking in those meeting DSM-5 diagnostic criteria for GAD. Comorbid depression, panic disorder, and PTSD were all uniquely associated with higher rates of GAD-related treatment seeking. Additionally, several accompanying anxiety symptoms were also uniquely predicted treatment seeking, including fatigue, panic attacks, reassurance-seeking, and interpersonal avoidance. Findings underscore the multi-factorial nature of treatment seeking behavior in GAD and highlight the need for further research to fully understand these relationships and devise effective strategies to improve treatment seeking in this population.</p></div>","PeriodicalId":48390,"journal":{"name":"Journal of Anxiety Disorders","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0