Research in Social & Administrative Pharmacy最新文献

{"title":"Collaborative pharmacist prescribing models in Australian hospitals: A scoping study","authors":"Hana Amer ,&nbsp;Sally Marotti ,&nbsp;Imaina Widagdo ,&nbsp;Sharon Goldsworthy ,&nbsp;Jacinta Johnson ,&nbsp;Lisa Kalisch Ellett","doi":"10.1016/j.sapharm.2025.09.006","DOIUrl":"10.1016/j.sapharm.2025.09.006","url":null,"abstract":"<div><h3>Background</h3><div>Collaborative pharmacist prescribing models have been trialled and implemented in Australian hospitals and involve credentialed pharmacists working with doctors and patients to develop patient medicine plans and prescribe medicines.</div></div><div><h3>Aim</h3><div>This study aimed to identify pharmacist prescribing policies and procedures in Australian hospitals and provide a narrative summary of the models and associated training.</div></div><div><h3>Method</h3><div>A scoping study was conducted using an exploratory and descriptive approach to identify and map pharmacist prescribing models implemented in Australian hospitals, and their associated training. Hospital pharmacy directors in Australia were contacted through a hospital pharmacy professional organisation in November 2023 and were asked to provide their pharmacist prescribing policies and procedures. Details of the models and training programs were extracted and summarised, with similarities and differences narratively reported.</div></div><div><h3>Results</h3><div>Fifteen different collaborative pharmacist prescribing models were reported to be implemented across more than 35 hospitals. Fourteen models had a formal training program. The models varied in scope of practice, particularly relating to medicine initiation and the timing of prescribing. The training and maintenance of currency of practice differed between models. Only three models recognised credentialing from other hospitals.</div></div><div><h3>Conclusion</h3><div>The study reveals variation in scope of practice, training, and credentialing processes between pharmacist prescribing models, with limited recognition and transferability of prescribing skills across jurisdictions in Australia. Efforts to establish national accreditation standards for pharmacist prescriber education programs and the recent introduction of a national credentialing program, could pave the way for the standardisation of the models and training within Australian hospitals.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 185-194"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the concept and definition of scope of practice in pharmacy: A scoping review","authors":"Mitchell Budden ,&nbsp;Shalom I. Benrimoj ,&nbsp;Francisco Martinez Mardones ,&nbsp;Sarah Dineen-Griffin","doi":"10.1016/j.sapharm.2025.09.007","DOIUrl":"10.1016/j.sapharm.2025.09.007","url":null,"abstract":"<div><h3>Background</h3><div>The term <em>scope of practice</em> (SOP) is gaining increasing traction within the pharmacy profession, reflecting its growing importance. Despite this, definitions and interpretations remain varied, as evidenced by the number of definitions and the variety of synonyms and adjectives used in the literature.</div></div><div><h3>Objectives</h3><div>(i) To examine the conceptual diversity in terminology used to describe SOP for the pharmacy profession across different jurisdictions; (ii) to propose a curated list of definitions and examples, along with recommended contexts for their application at local, national, and international levels.</div></div><div><h3>Methods</h3><div>A scoping review was conducted following JBI methodology and reported according to PRISMA-ScR guidelines. PubMed, Scopus, Web of Science, and Embase were searched to January 2025. Grey literature was explored using Google, the Overton database, and other methods. Titles and abstracts of identified records were screened, followed by full-text review against inclusion criteria. Definitions were systematically categorised to identify thematic patterns, overlaps, and distinctions, informing the development of a curated list of SOP definitions for pharmacy.</div></div><div><h3>Results</h3><div>Of 4,010 peer-reviewed records, 2,106 were screened after removing duplicates, with 31 publications meeting inclusion criteria. An additional 49 grey literature reports were included. A total of 172 definitions were compiled, capturing both phrasing and contextual application of SOP terminology. While no single universally accepted definition emerged, most aligned with three dominant conceptual themes.</div></div><div><h3>Conclusions</h3><div>The growing focus on pharmacy SOP highlights the need for a more unified and strategic framework. Consolidating definitions into a curated and accessible resource can improve clarity and consistency across educational, clinical, policy, and regulatory domains.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 195-208"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multisite pilot type 2 hybrid implementation-effectiveness trial of a community pharmacist-led model of collaborative care for Medication Assisted Treatment for Opioid Dependence: outcomes of the EPIC-MATOD trial","authors":"Suzanne Nielsen ,&nbsp;Francis Graham ,&nbsp;Mohammad Hossein Hadi ,&nbsp;Elizabeth Grist ,&nbsp;Bosco Rowland ,&nbsp;John Jackson ,&nbsp;Sarah Lord ,&nbsp;Jana Dostal ,&nbsp;Pene Wood ,&nbsp;Kirsty Morgan ,&nbsp;Dennis Petrie ,&nbsp;Ali Cheetham","doi":"10.1016/j.sapharm.2025.10.009","DOIUrl":"10.1016/j.sapharm.2025.10.009","url":null,"abstract":"<div><h3>Background</h3><div>Australia faces a critical challenge with access to opioid dependence treatment, particularly in regional areas where treatment shortages are amplified.</div></div><div><h3>Objective</h3><div>(s): To assess outcomes of a collaborative care model for opioid dependence treatment where community pharmacists work to their full scope of practice, in partnership with prescribers.</div></div><div><h3>Methods</h3><div>Community pharmacists and prescribers were recruited from the south-eastern suburbs of Melbourne, Victoria, Australia, to take part in a prospective, multisite, Type 2 hybrid implementation-effectiveness trial. Patients received collaborative prescriber/pharmacist care over a 6-month period, with outcomes compared to a non-randomised comparison group receiving usual care. Data was collected using a mixed methods approach with outcomes mapped to the RE-AIM framework. A health economics evaluation established time and costs associated with collaborative care.</div></div><div><h3>Results</h3><div>Collaborative care provided comparable outcomes on retention in treatment (97.2 %, 35/36) compared to the control cohort (89.8 %, 44/49) with no significant differences between groups on substance use or mental or physical health outcomes. Collaborative care was associated with significant increases in treatment satisfaction and quality adjusted life years (QALYs) and was cost-effective when compared to treatment as usual. The model was implemented with relatively high fidelity, with high levels of satisfaction among pharmacists, prescribers, and patients. Considerations for broader implementation included pharmacist workload, the need for secure communication software, and a mechanism to remunerate pharmacists for their time providing clinical care.</div></div><div><h3>Conclusion</h3><div>Pharmacist-led collaborative care for opioid dependence is feasible and acceptable and can provide an at least equivalent standard of care to usual care. Further research is required to establish how collaborative care can maximise prescriber capacity at scale.</div></div><div><h3>Clinical Trial registration</h3><div>ACTRN12621000871842.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 292-310"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145574774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Academic community pharmacy: A pilot Delphi study aimed at establishing a future common definition at the international level","authors":"Clémence Perraudin ,&nbsp;Noelia Amador-Fernandez ,&nbsp;Marie Paule Schneider ,&nbsp;Florent Macé ,&nbsp;Ralitza Gauthier ,&nbsp;Alice Panchaud ,&nbsp;Samuel Allemann ,&nbsp;Stefan Erni ,&nbsp;Jérôme Berger","doi":"10.1016/j.sapharm.2025.10.011","DOIUrl":"10.1016/j.sapharm.2025.10.011","url":null,"abstract":"<div><h3>Introduction</h3><div>The Granada statements promote the consistent use of appropriate terminology in pharmacy practice research. This pilot study aims to define the term <em>Academic Community Pharmacy</em> (ACP), providing a foundation for a forthcoming international study aimed at establishing a globally accepted definition.</div></div><div><h3>Methodology</h3><div>A Delphi study was conducted in 2023 among academic entities from all five Swiss universities involved in pharmacy practice research and education. The first definition comprised four kex elements: place of practice, clinical and academic activities and links with universities. Anonymous survey rounds were conducted where panellists assessed agreement with and clarity of the statements using a Likert scale. Additionally, free comments and proposals for changes were allowed. Consensus for each statement was defined as ≥66 % agreement.</div></div><div><h3>Results</h3><div>The panel consisted of nine members. Two Delphi rounds were needed to reach consensus for the final definition: “An ACP is a facility providing professional pharmacy services (according to a commonly accepted definition in the location of the considered ACP) to the community, conducting research and education on such services, and that has formal links (e.g., financial or contractual) with a university”.</div></div><div><h3>Conclusion</h3><div>Establishing a clear and consistent definition of ACPs will support their characterization and further development.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 357-361"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145373047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of pharmacist prescribing on health-related outcomes in secondary care compared with medical prescribing or no treatment: A systematic review","authors":"Amina Omosalewa Akintunde,&nbsp;Ajlin Karaxhija,&nbsp;Raisa Laaksonen","doi":"10.1016/j.sapharm.2025.11.003","DOIUrl":"10.1016/j.sapharm.2025.11.003","url":null,"abstract":"<div><h3>Background</h3><div>Pharmacist prescribing has gained momentum over the years and is currently utilised in Brazil, Canada, New Zealand, Poland, South Africa, United Kingdom (UK), and the United States of America (USA). While pharmacist prescribing has been associated with symptom improvement, reduced prescribing error rates, medication omissions, and improved medication access, the effects of pharmacist prescribing in secondary care have not been previously evaluated.</div></div><div><h3>Objectives</h3><div>This systematic review aimed to assess the effects of pharmacist prescribing on health-related outcomes in secondary care.</div></div><div><h3>Methods</h3><div>MEDLINE, Cochrane, CINAHL, Scopus, and Web of Science Core Collection databases were searched for studies published in English from database inception to October 3, 2024. Studies were included if the intervention was pharmacist prescribing and the outcomes were health-related and measurable. Narrative synthesis of the outcomes from included studies was conducted.</div></div><div><h3>Results</h3><div>A total of 21 studies from five countries (Australia, Egypt, Hong Kong, UK, USA) were included. Pharmacist prescribing significantly improved disease management, reduced the number of hospital revisits, improved blood pressure control, international normalised ratio control and decreased the number of adverse events when compared to medical prescribing. The evidence further suggests that the healthcare costs per patient per month, median cost of treatment, inpatient hospitalisations and emergency department admissions were significantly lower when pharmacists prescribed medicines. The evidence was low to moderate quality.</div></div><div><h3>Conclusion</h3><div>This systematic review provides evidence that pharmacist prescribing has a positive effect on therapeutic outcomes, and that pharmacist prescribing is comparable or better than medical prescribing in secondary care.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 254-262"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enabling real-world community pharmacy research: A realist review of practice-based research networks (PBRNs)","authors":"Louisa Handyside ,&nbsp;Jacqui Cameron ,&nbsp;Christopher Freeman","doi":"10.1016/j.sapharm.2025.10.004","DOIUrl":"10.1016/j.sapharm.2025.10.004","url":null,"abstract":"<div><h3>Background</h3><div>Engaging pharmacists in research and bridging the research-practice divide is a persistent challenge. Practice-based research networks aim to support research engagement, overcome research barriers, and generate evidence to advance practice. However, the outcomes of existing networks remain unexplored. Thus, the objectives of this realist review are: 1) to develop and refine a realist program theory to explain how and why these networks support research engagement and knowledge translation, for whom and in what contexts and 2) to provide preliminary recommendations to optimise network outcomes.</div></div><div><h3>Methods</h3><div>An initial program theory was developed, followed by an iterative process of formal and complementary searching. Data was selected, appraised, extracted, organised, and synthesised using a realist approach to refine the program theory.</div></div><div><h3>Results</h3><div>The refined program theory consisted of 12 context-mechanism-outcome configurations that explain the two key drivers of network success: 1) mutual benefits for a diverse range of actively engaged researchers and pharmacists, and 2) sustainable resourcing and maintenance of strategic collaborative partnerships. Stakeholder recommendations are underpinned by the modifiable contexts and resources that underscore optimal network outcomes.</div></div><div><h3>Conclusion</h3><div>A realist program theory was developed to explain how research networks may be used to bridge the divide between research and community pharmacy practice. The theory explains the causal processes underpinning successful outcomes and informs preliminary recommendations for network development, implementation, and maintenance. The review provides a robust foundation to explain how networks can optimise community pharmacy research. Futher research is warranted to confirm their translational potential.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 209-221"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for, and overcoming, ‘pill aversion’ in community pharmacy using a novel educational tool: Hard pill to swallow?™","authors":"Alice. P. McCloskey ,&nbsp;Johanne Nesbit ,&nbsp;A.P. Rathbone ,&nbsp;Nicola Vasey ,&nbsp;Philippa. G. McCabe ,&nbsp;Susan Flynn ,&nbsp;Simran Bal ,&nbsp;Katie Mulraney ,&nbsp;Sarah Hamilton ,&nbsp;Hashim Ali ,&nbsp;Kyle Holebrooke-Steele ,&nbsp;Yincent Tse ,&nbsp;Emma. J. Lim","doi":"10.1016/j.sapharm.2025.11.007","DOIUrl":"10.1016/j.sapharm.2025.11.007","url":null,"abstract":"<div><h3>Background</h3><div>Solid oral dosage forms (pills) are commonly dispensed but frequently patients struggle to take these (pill aversion). This is rarely identified or addressed in clinical practice. The KidzMed programme teaches children to swallow pills, but to date it has not been used to support adults with pill aversion.</div></div><div><h3>Objectives</h3><div><ul><li><span>•</span><span><div>Assess in community pharmacy the acceptability of screening for pill aversion</div></span></li><li><span>•</span><span><div>Test an educational leaflet tailored for adults to support with pill swallowing</div></span></li></ul></div></div><div><h3>Methods</h3><div>Participants were recruited via pre-defined inclusion and exclusion criteria using convenience sampling at three Liverpool-based community pharmacies over a one-month period. A screening questionnaire was completed and adults &gt;18 years identified with pill aversion (score of 6+ on the PILL-5 screening tool) supplied with an adapted educational leaflet from the KidzMed programme. Successful pill swallowing using the leaflet was assessed via phone-call two weeks later. Institutional ethics reference (PBS/2023-23/01).</div></div><div><h3>Results</h3><div>Overall, 246 participants were screened, 9 % (n = 22) were identified as having pill aversion. There was an association with younger age and female gender. Follow-up showed that the leaflet was well received, participants found it useful, had changed their pill swallowing technique because of it, and shared this knowledge with others.</div></div><div><h3>Conclusions</h3><div>Pill aversion is an underexplored issue. The positive impact of the adapted leaflet in adults reflects the success of KidzMed for children. Further work is needed to confirm the association of age and gender with pill aversion, and determine translatability of the adapted leaflet to a wider audience and other healthcare settings.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 340-347"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A digital health-supported community pharmacy-based lifestyle intervention program for overweight or obese adults with prediabetes, the PRediabetes Intervention, Management and Evaluation (PRIME) Program: A cluster randomized controlled trial","authors":"Kah Woon Teoh ,&nbsp;Choon Ming Ng ,&nbsp;Chun Wie Chong ,&nbsp;Yi Ling Ng ,&nbsp;J Simon Bell ,&nbsp;Shaun Wen Huey Lee","doi":"10.1016/j.sapharm.2025.10.002","DOIUrl":"10.1016/j.sapharm.2025.10.002","url":null,"abstract":"<div><h3>Background</h3><div>Evidence on the impact of using digital health tools to facilitate prediabetes management in community pharmacies is lacking. This study aimed to evaluate the effects of a digital health-supported and community pharmacy-based lifestyle intervention (PRIME) program on individuals with prediabetes in Malaysia.</div></div><div><h3>Methods</h3><div>A two-arm cluster randomised controlled trial was conducted in 16 community pharmacies from two states in Malaysia and included people with prediabetes that were overweight or obese. The intervention group received support of in-depth counselling from pharmacists, in-app prediabetes education modules, and peer support, while the usual care group received counselling based on pharmacists’ usual practice. The primary outcomes were the proportion of participants achieving ≥5 % weight loss and differential change in weight. All analyses were performed using intention to treat analyses with mixed effect modelling.</div></div><div><h3>Findings</h3><div>Ninety-one participants (intervention, n = 46; usual care n = 45) were recruited. At the end of study, participants in the intervention group were twice as likely compared to the usual care group to report a minimum 5 % weight loss (21 % intervention and 7.5 % usual care participants, odds ratio: 2.5, p = 0.266). Intervention group participants also reported a larger weight loss, with a mean difference of 1.26 kg (95 %CI -2.36 kg to −0.15 kg) between groups. These differences were more significant especially among those who were more engaged with PRIME.</div></div><div><h3>Conclusion</h3><div>The intervention showed greater weight loss than the usual care, but the proportion of individuals achieving clinically meaningful weight loss (≥5 %) was not significant. PRIME program can be an important and useful tool to improve risk factors among individuals with prediabetes especially in a low-resource setting. Further research is needed to determine the economic and long-term sustainability of such programs.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 272-282"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of pharmacist-led interventions on economic, clinical, and humanistic outcomes (ECHO) in patients admitted to emergency departments: A systematic review of randomized controlled trials","authors":"Emre Kara ,&nbsp;Betul Okuyan ,&nbsp;Cansu Goncuoglu ,&nbsp;Kutay Demirkan ,&nbsp;Shusen Sun","doi":"10.1016/j.sapharm.2025.10.007","DOIUrl":"10.1016/j.sapharm.2025.10.007","url":null,"abstract":"<div><h3>Background</h3><div>The role of pharmacists in emergency departments (EDs) has undergone a significant transformation globally, expanding beyond traditional responsibilities to include various clinical activities that promise to enhance patient outcomes. However, the full potential of these interventions, particularly from economic, clinical, and humanistic (ECHO) perspectives, remains to be systematically explored. The aim of this study was to evaluate the impact of pharmacist-led interventions on ECHO among patients admitted to the ED.</div></div><div><h3>Methods</h3><div>This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Searches were conducted in PubMed, MEDLINE, and International Pharmaceutical Abstracts, focusing on randomized controlled trials (RCTs) published in English that involved pharmacist interventions in EDs. Data were extracted on study design, pharmacist interventions, and patient outcomes. Cochrane risk-of-bias tool for randomized trials (RoB 2.0) was used.</div></div><div><h3>Results</h3><div>Twelve RCTs that met the inclusion criteria were identified. The studies were conducted predominantly in tertiary care settings in various countries. The most common interventions performed by pharmacists included medication reconciliation, obtaining medication histories, and patient education. The review showed that pharmacist interventions tend to improve medication safety and patient satisfaction but varied significantly in their execution and reported outcomes. No studies comprehensively analyzed economic outcomes, and only a few addressed humanistic outcomes.</div></div><div><h3>Conclusions</h3><div>Pharmacy-led services improved clinical outcomes, however there was lack of studies showing the economic and humanistic outcomes of these services. The need for standardized protocols and further research to establish their broader impacts should be considered. The findings support the continued integration and expansion of pharmacist roles in emergency care, which could influence global policy and practice in healthcare systems.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 222-231"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of pharmacist-led medication reconciliation and usual care on detecting and resolving discrepancies in major orthopaedic surgeries: A quasi-experimental study","authors":"Karen R. Palermo ,&nbsp;Jesús Cotrina Luque ,&nbsp;Natália Marto ,&nbsp;Miriam Capoulas ,&nbsp;Cláudia Santos ,&nbsp;Isabel V. Figueiredo ,&nbsp;Margarida Castel-Branco","doi":"10.1016/j.sapharm.2025.10.001","DOIUrl":"10.1016/j.sapharm.2025.10.001","url":null,"abstract":"<div><h3>Background</h3><div>Medication reconciliation can reduce errors, particularly among elderly and polymedicated patients. The inclusion of pharmacists obtaining the best possible medication history can further improve the identification and resolution of discrepancies.</div></div><div><h3>Aim</h3><div>To compare a structured pharmacist-led medication reconciliation program with usual care on detecting and resolving discrepancies during hospital admission for major orthopaedic surgeries.</div></div><div><h3>Methods</h3><div>Quasi-experimental study, conducted in a Portuguese tertiary hospital, involving adult patients undergoing major orthopaedic surgery and taking chronic medication. In Phase One (usual care), reconciliation lacked standardization; pharmacists performed it alongside other tasks, relying solely on medical records and reported unintentional discrepancies electronically to prescribers. In Phase Two (pharmacist-led medication reconciliation), a designated pharmacist obtained the best possible medication history, identified discrepancies and communicated them directly to clinical pharmacologists. Validated high-risk criteria were used to assess clinical significance. Primary outcomes were identifying, classifying, and resolving unintentional discrepancies across both phases.</div></div><div><h3>Results</h3><div>The study included 182 patients (91 in each phase). In Phase One, 212 discrepancies were identified, 91 were unintentional, of which 30 had clinical significance. Ten pharmacist interventions were performed, with 50 % acceptance rate. In Phase Two, 339 discrepancies were identified, 129 were unintentional, of which 46 had clinical significance. A total of 104 pharmacist interventions were performed, with 73 % acceptance rate. Identification and resolution of unintentional discrepancies significantly increased (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>Pharmacist-led medication reconciliation, focusing on the best possible medication history collection and direct contact with physicians, significantly increased the identification and resolution of discrepancies, underlining its role in enhancing patient safety.</div></div>","PeriodicalId":48126,"journal":{"name":"Research in Social & Administrative Pharmacy","volume":"22 2","pages":"Pages 263-271"},"PeriodicalIF":2.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}