European Eating Disorders Review最新文献_第3页

GDF15 Is Elevated in Eating Disorders and Is Involved in the Gut-Brain Axis via Ghrelin. GDF15在饮食失调中升高，并通过胃饥饿素参与肠脑轴

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-24 DOI: 10.1002/erv.70018

Livio Tarchi, Giulia Brancolini, Sara Giachetti, Gaia Maiolini, Emanuele Cassioli, Eleonora Rossi, Gianluca Villa, Rachele Garella, Roberta Squecco, Paolo Rovero, Paolo Comeglio, Valdo Ricca, Francesco De Logu, Romina Nassini, Giovanni Castellini

{"title":"GDF15 Is Elevated in Eating Disorders and Is Involved in the Gut-Brain Axis via Ghrelin.","authors":"Livio Tarchi, Giulia Brancolini, Sara Giachetti, Gaia Maiolini, Emanuele Cassioli, Eleonora Rossi, Gianluca Villa, Rachele Garella, Roberta Squecco, Paolo Rovero, Paolo Comeglio, Valdo Ricca, Francesco De Logu, Romina Nassini, Giovanni Castellini","doi":"10.1002/erv.70018","DOIUrl":"https://doi.org/10.1002/erv.70018","url":null,"abstract":"Objective: GDF15 induces anorexia and visceral discomfort, regulating appetite, food intake and potentially metabolic responses. However, its role in eating disorders remains unexplored.Method: A total of 145 participants were recruited (60 patients with anorexia nervosa, 20 with bulimia nervosa, 13 with binge eating disorder, 52 participants from the general population). Ghrelin and GDF15 serum levels were measured with immunosorbent assay kits.Results: Ghrelin was elevated in patients with an eating disorder compared to healthy controls (age and BMI-adjusted ANCOVA, F-value 4.084, p-value 0.008). GDF15 was significantly correlated with ghrelin (Spearman rho 0.430, p-value < 0.001) and BMI (rho = -0.176, p-value = 0.025). GDF15 predicted the BMI of patients with anorexia nervosa and individuals from the general population, again being elevated at lower BMI (linear regression beta -0.254, p-value 0.005). The effect of GDF15 on BMI was observed as under the mediation of ghrelin (direct effect -0.056, p-value 0.577; indirect effect -0.199, p-value < 0.001).Conclusions: Present results provide novel insights into the role of GDF15 in eating disorders, describing its serum level in this clinical population for the first time. In addition, a positive correlation between GDF15 and ghrelin serum levels is also reported for the first time.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of the ECHOMANTRA Individual Online Intervention to Support Recovery From Eating Disorders in Adolescent Patients: A Randomized Controlled Trial. ECHOMANTRA个人在线干预支持青少年饮食失调患者康复的有效性：一项随机对照试验。

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-21 DOI: 10.1002/erv.70013

A Ruiz, Y Quiles, E León, M L Vila, G Piera, A Navarro, G Pagán, M Segura, I Agulló, G Llorca, C Romero, M España

{"title":"Efficacy of the ECHOMANTRA Individual Online Intervention to Support Recovery From Eating Disorders in Adolescent Patients: A Randomized Controlled Trial.","authors":"A Ruiz, Y Quiles, E León, M L Vila, G Piera, A Navarro, G Pagán, M Segura, I Agulló, G Llorca, C Romero, M España","doi":"10.1002/erv.70013","DOIUrl":"https://doi.org/10.1002/erv.70013","url":null,"abstract":"Introduction: ECHOMANTRA supports both patients and carers as an adjunct to treatment in Eating Disorders (Eds).Objective: This study evaluates the efficacy, acceptability, and feasibility of ECHOMANTRA as an add-on to treatment-as-usual (TAU) for adolescent ED patients and their carers, using an individualised online format.Method: A multicenter, randomized controlled trial compared two parallel groups (TAU + ECHOMANTRA vs. TAU alone) with 108 patient-carer dyads.Results: Patients in both groups showed improvements in BMI, ED symptoms, emotional state, quality of life, confidence in change, obsessiveness, and perfectionism, with larger effects in the ECHOMANTRA + TAU group. Carers in both groups improved in expressed emotion, accommodation, perceived ED impact, and emotional well-being, with greater effects in the ECHOMANTRA + TAU group. Only carers in this group improved in caregiver skills. Completion rates were high (patients: 87.04%, carers: 81.84%), with strong satisfaction.Conclusions: ECHOMANTRA is an effective, feasible online intervention that enhances outcomes for adolescent ED patients and carers when added to standard care.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparison of Psychiatric Comorbid Symptomology Between Adolescents With Restrictive/Avoidant Food Intake Disorder, Anorexia Nervosa and Atypical Anorexia Nervosa. 青少年限制性/回避性食物摄入障碍、神经性厌食症和非典型神经性厌食症的精神共病症状比较

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-19 DOI: 10.1002/erv.70014

Daniel Wilson, Govind Krishnamorthy, Renata A Mendes, Tania Withington, Melanie Dalton, Natalie J Loxton

{"title":"A Comparison of Psychiatric Comorbid Symptomology Between Adolescents With Restrictive/Avoidant Food Intake Disorder, Anorexia Nervosa and Atypical Anorexia Nervosa.","authors":"Daniel Wilson, Govind Krishnamorthy, Renata A Mendes, Tania Withington, Melanie Dalton, Natalie J Loxton","doi":"10.1002/erv.70014","DOIUrl":"https://doi.org/10.1002/erv.70014","url":null,"abstract":"Objective: Psychiatric comorbid conditions are common among individuals with Eating Disorders (EDs), and these symptoms may exacerbate and/or interact with ED symptoms and impact treatment effectiveness. Whilst comorbid symptomology in Anorexia Nervosa (AN) has been well described, less is known about how the 'newer' ED diagnoses of Atypical Anorexia Nervosa (AAN) and Avoidant/Restrictive Food Intake Disorder (ARFID) differ relative to AN. The current study aimed to extend the literature by examining similarities and differences in comorbid symptomology AN, AAN, and ARFID groups.Method: In this cross-sectional study, young people (n = 311, female = 87.8%, mean age = 14.32: SD = 2.05, range 5-17) with AN, AAN, and ARFID completed self-report measures capturing comorbid symptomology prior to engaging in treatment at a specialist ED outpatient clinic.Results: There was no difference between AN and AAN on any measure of comorbid symptoms. Both showed severe levels of comorbidity with over half exceeding the cut-point for four or more comorbid diagnoses, with Obsessive Compulsive Disorder, depression and Social Anxiety particularly common. ARFID, on the other hand, had comparatively less severe comorbid symptoms compared to AN and AAN.Conclusions: Findings provide a better understanding of the nature of comorbid symptomology among these disorders and encourages future research to investigate the role that they play in the treatment outcome.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endorsement of Avoidant/Restrictive Eating Motivations Across Restrictive Eating Disorders: A Trait- and State-Level Examination. 在限制性饮食障碍中对回避/限制性饮食动机的认可：一项特质和国家层面的检查。

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-17 DOI: 10.1002/erv.70016

Vittoria Trolio, Ege Biçaker, Alexia E Miller, Sarah E Racine

{"title":"Endorsement of Avoidant/Restrictive Eating Motivations Across Restrictive Eating Disorders: A Trait- and State-Level Examination.","authors":"Vittoria Trolio, Ege Biçaker, Alexia E Miller, Sarah E Racine","doi":"10.1002/erv.70016","DOIUrl":"https://doi.org/10.1002/erv.70016","url":null,"abstract":"Objective: Research on avoidant/restrictive food intake disorder (ARFID) and anorexia nervosa (AN) has emphasised differences between these disorders, but similarities maintaining dietary restriction may be overlooked. ARFID-related eating disturbances may also occur and facilitate egosyntonic restriction in AN.Method: Using the Nine Item ARFID Screen (NIAS; N = 141) and ecological momentary assessment (N = 76), we examined endorsement of ARFID-related and traditional eating disorder (ED) reasons for restrictive eating in women with ARFID, AN-restrictive subtype (AN-R), AN binge eating/purging subtype (AN-BP), and controls.Results: Clinical groups scored higher on NIAS subscales than controls. ARFID participants scored higher on NIAS-Picky than AN groups, and higher on NIAS-Fears and NIAS-Appetite than AN-BP, while AN-R did not differ from either. For skipped meals, ARFID and AN-R did not differ on ratings of avoidant/restrictive motivations, while AN-BP did not differ from either on fears of aversive consequences. For restriction at meal/snack, ARFID did not differ from AN-R on endorsement of picky eating nor AN-BP on lack of interest but endorsed stronger fears of aversive consequences.Conclusions: While sensory sensitivity/picky eating appears unique to primarily-restrictive EDs, lack of interest was common across clinical groups. Results highlight differences and potential transdiagnostic treatment targets.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Negative Social Feedback on Wanting and Liking of Food Pictures in Anorexia Nervosa. 负面社会反馈对神经性厌食症患者食物图片欲望和喜爱的影响。

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-16 DOI: 10.1002/erv.70012

Ludovica Natali, Valentina Cardi, Chiara Tosi, Enrico Collantoni, Chiara Caulo, Francesca Fontana, Alessandra Sala, Enrico Ceccato, Palmiero Monteleone, Angela Favaro, Valentina Meregalli

{"title":"The Impact of Negative Social Feedback on Wanting and Liking of Food Pictures in Anorexia Nervosa.","authors":"Ludovica Natali, Valentina Cardi, Chiara Tosi, Enrico Collantoni, Chiara Caulo, Francesca Fontana, Alessandra Sala, Enrico Ceccato, Palmiero Monteleone, Angela Favaro, Valentina Meregalli","doi":"10.1002/erv.70012","DOIUrl":"https://doi.org/10.1002/erv.70012","url":null,"abstract":"Objective: Negative emotional states have been found to predict food cravings and consumption in the general population. People with a persistent tendency to restrict food intake, however, might be eating less when sad, angry, or stressed. In this study, the impact of inducing a negative emotional state through social exclusion on wanting and liking of food pictures was explored in patients with anorexia nervosa.Method: 43 patients with anorexia nervosa and 22 healthy controls completed a computerised social rejection and food appraisal task. Participants viewed short videos in which a stranger made either a negative comment directed toward them or a neutral comment. After each video, participants rated their affective state, as well as their wanting and liking for pictures of high-calorie foods.Results: Participants in both groups experienced greater negative affect after viewing the negative videos compared to the neutral ones. They also reported lower wanting for high-calorie foods following negative videos, while no significant effects were observed for liking scores. Interestingly, patients with higher body mass index exhibited a greater reduction in both food wanting and liking following negative videos.Conclusions: These results suggest that negative social interactions can exacerbate restrictive behaviours, especially in patients who are recovering weight during treatment.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Food Addiction Is Strongly Associated With Psychopathology and Reduced Psychological Well-Being Among Adults Irrespective of BMI. 在成年人中，食物成瘾与精神病理和心理健康下降密切相关，而与BMI无关。

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-14 DOI: 10.1002/erv.70011

Christina Horsager, Emil Færk, Jens Meldgaard Bruun, Marlene B Lauritsen, Søren Dinesen Østergaard

{"title":"Food Addiction Is Strongly Associated With Psychopathology and Reduced Psychological Well-Being Among Adults Irrespective of BMI.","authors":"Christina Horsager, Emil Færk, Jens Meldgaard Bruun, Marlene B Lauritsen, Søren Dinesen Østergaard","doi":"10.1002/erv.70011","DOIUrl":"https://doi.org/10.1002/erv.70011","url":null,"abstract":"Background and aims: Food addiction has been linked to psychopathology and reduced psychological well-being. Here, we investigated whether these associations are mainly driven by food addiction itself or mediated via an increase in BMI.Methods: Data stem from a nationwide survey from Denmark (n = 1474 participants). The survey questionnaire included the Yale Food Addiction Scale 2.0 (YFAS 2.0) measuring food addiction, questions on height and weight (to compute BMI), and a range of self-reported measures of psychopathology and psychological well-being. The association between food addiction and psychopathology/psychological well-being, stratified by weight category (normal weight (BMI 18.5-24.9), overweight (BMI 25-29.9) and obesity (BMI ≥ 30)), was assessed via multivariable regression analyses, adjusted for sex, age, socioeconomic status and BMI.Results: Across all BMI categories, having food addiction was strongly positively associated with psychopathology (depression, anxiety, and interpersonal sensitivity) and strongly negatively associated with psychological well-being (all p-values < 0.001), despite adjustment for BMI. These associations remained following exclusion of participants either having received a diagnosis of mental disorder or having redeemed a prescription for psychopharmacological treatment.Conclusion: The findings from this study are compatible with food addiction itself, and not increased BMI likely arising from it, being associated with psychopathology and reduced psychological well-being.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ecological Momentary Assessment of Impulsivity and Overeating and Loss of Control Eating in Adolescents. 青少年冲动、暴饮暴食和饮食失控的生态瞬时评估。

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-11 DOI: 10.1002/erv.70010

Tyler B Mason, Diego Hernandez, Jeremy C Morales, Genevieve F Dunton

{"title":"Ecological Momentary Assessment of Impulsivity and Overeating and Loss of Control Eating in Adolescents.","authors":"Tyler B Mason, Diego Hernandez, Jeremy C Morales, Genevieve F Dunton","doi":"10.1002/erv.70010","DOIUrl":"https://doi.org/10.1002/erv.70010","url":null,"abstract":"Objectives: Impulsivity has been linked to overeating and loss of control eating (LOCE), yet most adolescent research has focused on between-subjects (i.e., trait) impulsivity; thus, less is known about how within-subjects (i.e., state) impulsivity predicts overeating and LOCE. Given this gap, this study used ecological momentary assessment (EMA) to examine the construct validity of the four-item Momentary Impulsiveness Scale (MIS) in adolescents and the relationship between within- and between-subjects impulsivity and overeating and LOCE.Methods: Seventy-four adolescents (Mage = 15.68) completed a 10-day EMA protocol, reporting impulsivity (measured with the MIS) and eating behaviours multiple times daily. Generalised linear mixed models were run examining associations between baseline impulsivity measures and EMA impulsivity and impulsivity, disaggregated into within- and between-subjects effects, as a prospective predictor of overeating and LOCE.Results: Generally, baseline impulsivity measures predicted elevated EMA impulsivity. Also, higher within-subject impulsivity significantly predicted greater LOCE and higher between-subject impulsivity was significantly associated with greater overeating and LOCE.Discussion: Analyses demonstrated concordance between baseline and EMA impulsivity measures in adolescents and suggested that state impulsivity impacts the perceived control over eating. Adolescent preventions/interventions that provide strategies to reduce or mitigate state impulsivity warrant further investigation (e.g., providing in-the-moment self-regulatory strategies when feeling impulsive).","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review. 神经性厌食症和体重过轻患者抑郁的药物治疗效果：系统综述。

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-11 DOI: 10.1002/erv.70008

M J Besjes, S H W Mares, A A van Elburg, J Spijker

{"title":"The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review.","authors":"M J Besjes, S H W Mares, A A van Elburg, J Spijker","doi":"10.1002/erv.70008","DOIUrl":"https://doi.org/10.1002/erv.70008","url":null,"abstract":"Objective: Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals.Method: A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025. Nineteen studies with 477 underweight patients were included, involving pharmacological treatment of depressed underweight young adults. Study designs ranged from randomised controlled trials (RCTs) to open-label trials and case reports, with quality assessments performed. Most studies focused on patients with AN; a few included underweight individuals without eating disorders.Results: No RCTs specifically examined antidepressant treatment for MDD in AN. Most studies prioritised weight restoration and eating disorder symptoms over depressive outcomes. Some case reports indicated potential benefits of medications such as mirtazapine and ketamine. However, evidence was mixed and generally low in quality. Overall, it shows insufficient evidence for the effectiveness of pharmacological treatments in underweight individuals. There is insufficient data to determine whether being underweight affects antidepressant efficacy.Conclusions: Evidence on pharmacological treatment of MDD in underweight individuals, particularly those with AN, is scarce and inconclusive. Well-designed RCTs are needed to assess the efficacy and safety of antidepressants in this population.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations Between the Use of Fitness and Diet Tracking Technology and Disordered Eating Behaviour: A Systematic Review. 使用健身和饮食跟踪技术与饮食紊乱行为之间的关系：系统综述。

IF 3.9 2区心理学

European Eating Disorders Review Pub Date : 2025-07-10 DOI: 10.1002/erv.70006

Sarah Moody, Lindsay Ross, Marie-Christine Opitz, Amelia Hemmings, Başak İnce, Callum Bryson, Carina Kuehne, Daire Douglas, Matthew Phillips, Vivienne Langhorne, Ulrike Schmidt, Helen Sharpe

{"title":"Associations Between the Use of Fitness and Diet Tracking Technology and Disordered Eating Behaviour: A Systematic Review.","authors":"Sarah Moody, Lindsay Ross, Marie-Christine Opitz, Amelia Hemmings, Başak İnce, Callum Bryson, Carina Kuehne, Daire Douglas, Matthew Phillips, Vivienne Langhorne, Ulrike Schmidt, Helen Sharpe","doi":"10.1002/erv.70006","DOIUrl":"https://doi.org/10.1002/erv.70006","url":null,"abstract":"Background: The fitness and wellbeing technology industry is growing rapidly. Concerns are emerging regarding whether these may increase disordered eating behaviours. This review is the first to systematically examine the relationship between fitness and diet tracker use and disordered eating in general and clinical populations.Methods: The following databases were searched: EMBASE, Medline/PubMed, PsychInfo, CINAHL Plus, ERIC, SportDiscus, ASSIA, Social Science Premium, Sociological Abstracts, Sports Medicine and Educational Health, SCOPUS, Cochrane Library, and ProQuest Dissertation and Theses Global. Studies were selected using predetermined inclusion and exclusion criteria. A narrative synthesis was used, and results were reported by disordered eating outcome.Results: Twenty-seven studies were included in the final review. Cross-sectional studies revealed reasonably consistent evidence of an association between disordered eating and fitness and diet tracker use, specifically regarding global disordered eating, dietary restraint, excessive exercise, and disordered muscle-orientated behaviour. However, this association was not replicated in experimental research.Conclusion: While fitness and diet tracker use is a correlate of disordered eating, it is currently not possible to conclude if they increase disordered eating, or the direction of this relationship. Future research should determine the nature of this relationship and possible mechanisms to ensure their safe use in vulnerable populations.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Adjunct Olanzapine Treatment in Adolescents With Anorexia Nervosa: A Comparison of Two Patient Cohorts. 奥氮平辅助治疗青少年神经性厌食症的疗效：两组患者的比较。

IF 3.4 2区心理学

European Eating Disorders Review Pub Date : 2025-07-09 DOI: 10.1002/erv.70009

Helene Krauss, Michael Zeiler, Dunja Mairhofer, Julia Klang, Julia Schwarzenberg, Michaela Mitterer, Gudrun Wagner, Maria Glüder, Karin Egberts, Manfred Gerlach, Andreas Karwautz

{"title":"Efficacy of Adjunct Olanzapine Treatment in Adolescents With Anorexia Nervosa: A Comparison of Two Patient Cohorts.","authors":"Helene Krauss, Michael Zeiler, Dunja Mairhofer, Julia Klang, Julia Schwarzenberg, Michaela Mitterer, Gudrun Wagner, Maria Glüder, Karin Egberts, Manfred Gerlach, Andreas Karwautz","doi":"10.1002/erv.70009","DOIUrl":"https://doi.org/10.1002/erv.70009","url":null,"abstract":"Background: Anorexia nervosa (AN) is a severe psychiatric disorder with high mortality, requiring innovative treatment strategies. Olanzapine (OLZ), an atypical antipsychotic, has demonstrated efficacy in promoting weight gain and reducing psychopathological symptoms in adults with AN. However, its efficacy and safety in adolescents remain insufficiently explored.Objective: This study assessed the impact of adjunctive OLZ in adolescents with AN during inpatient care, focussing on weight gain, eating disorder pathology, and metabolic safety.Methods: A naturalistic, prospective study compared two groups of adolescent inpatients with AN (n = 47 each), one receiving standard multidisciplinary care plus OLZ and one receiving standard care alone (Non-OLZ). Weekly weight gain as well as admission-to-discharge changes in body-mass-index, eating disorder symptoms, and metabolic markers were compared between the two cohorts.Results: The OLZ group (∅ 9 mg/day) achieved greater weekly weight gain (0.898 vs. 0.677 kg, p = 0.004) compared to the Non-OLZ group. Both groups showed similar reductions in eating disorder pathology; however, improvements in body dissatisfaction were larger in the Non-OLZ group. Administration of OLZ was associated with significant prolactin level increases.Conclusions: OLZ is a promising adjunctive treatment for adolescents in terms of supporting weight gain during inpatient care. However, psychological effects and possible metabolic risks warrant further study.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0