Current Indian Science最新文献

{"title":"Bearing Capacity of Skirted Ring Footing on Dense Sand Overlying Loose Sand","authors":"Rakesh Kumar Dutta, Priyanka Choudhary B.","doi":"10.2174/2210299x01666230912144929","DOIUrl":"https://doi.org/10.2174/2210299x01666230912144929","url":null,"abstract":"Introduction: The ultimate bearing capacity of an unskirted/skirted ring foundation on dense sand overlying loose sand is estimated using finite element analysis in this study. Method: The range of thickness ratio (thickness of top dense sand layer divided by external diameter of ring) was kept between 0.25 and 1.5. The friction angle of the upper dense and bottom loose sand layers was maintained between 40° and 44° and 30° and 34°, respectively. In the case of skirted ring footing, the skirts are attached at the inner edge, outer edge, and both the edges, respectively. Result: According to the results, the bearing capacity increases with an increase in either the friction angle of upper dense and lower loose sand layers or the thickness ratio. A double-skirted ring footing was observed to provide the greatest bearing capacity, followed by footing with skirts attached at the outer and inner edges, respectively. Conclusion: To sum up, the bearing capacity of the ring footing was higher than the circular footing for the given friction angle of the top and bottom layer and thickness ratio.","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135885294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical screening and antioxidant activity of roots of Plumbago zeylanica L.","authors":"Poonam Kushwaha, Babita Shukla","doi":"10.2174/2210299x01666230815142606","DOIUrl":"https://doi.org/10.2174/2210299x01666230815142606","url":null,"abstract":"Background: P. zeylanica L. is a well-known herbal plant that has long been used for its therapeutic properties. The present study aimed to carry out phytochemical screening to determine the total phenolic and flavonoid content as well as to evaluate the antioxidant properties of the methanolic extract of the root of Plumbago zeylanica L. Methods: The antioxidant activity of the extract was assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH), nitric oxide scavenging, and hydroxyl radical scavenging assays. Results: The phenolic and flavonoid contents of the extracts were 2.4% and 16.5%, respectively. P. zeylanica was found to scavenge free radicals with substantial antioxidant properties, exhibiting a high flavonoid and phenolic content. These results also suggest a strong correlation between antioxidant activities, as well as phenolic and flavonoid contents. Conclusion: The plant sample exhibited superior free radical scavenging activity and phytochemical constituents that might be useful for further research on fighting oxidative stress.","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135114521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive Furanocoumarin ‘Alloimperatorin’: Therapeutic Importance and Pharmacological Activities in Medicine","authors":"Dinesh Kumar Patel","doi":"10.2174/2210299x01666230124105950","DOIUrl":"https://doi.org/10.2174/2210299x01666230124105950","url":null,"abstract":"Background: Plants and their derived phytochemicals commonly called secondary metabolites have been used in medicine as a good source of medicine for the treatment of numerous kinds of human disorders and associated complications. Herbal medicines have been used in modern medicine for the treatment of some chronic disorders, including cancer. Coumarins class phytochemicals are important in medicine and mainly derived from plant sources, including Angiosperms. Coumarins have numerous biological activities including antimicrobial, antibacterial, antifungal, antioxidant, antitumor, anti-HIV, antihypertension, anticoagulant, anticancer, antiviral, anti-inflammatory, analgesics, antidiabetic, and anti-depressive. Methods: Here in the present work, numerous scientific data were collected from different scientific databases and analyzed in order to know the biological potential of alloimperatorin in medicine. Google, Google Scholar, PubMed, and Scopus databases were searched and analyzed to know the medicinal properties and therapeutic potential of alloimperatorin. Therapeutic potential of alloimperatorin was investigated in the present work through scientific data analysis of different scientific research work. Pharmacological activities of alloimperatorin were analyzed in the present work to know the beneficial health aspects of alloimperatorin against various forms of human disorders. Results: Scientific data analysis of different research work revealed the therapeutic potential of alloimperatorin in medicine. Alloimperatorin is a coumarin class phytochemical found in the Angelica dahurica. Alloimperatorin revealed significant therapeutic potential in medicine mainly due to its anti-oxidative, anti-inflammatory, anti-apoptotic potential, however its biological potential in breast cancer and their photosensitization effect were also discussed in the present work. Analytical data signified the presence of alloimperatorin in different medicinal plants. Conclusion: Present work signified the biological importance and therapeutic potential of alloimperatorin in medicine.","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135474035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical, Medicinal, and Green Approaches of Allamanda cathartica L.: A Mini Review","authors":"Ishwar Prakash Sharma, Acharya Balkrishna, Akansha Saini, Rachna Bhandari, Vedpriya Arya","doi":"10.2174/2210299x01666221221095214","DOIUrl":"https://doi.org/10.2174/2210299x01666221221095214","url":null,"abstract":"Abstract: Allamanda cathartica L. belongs to the family Apocynaceae and is a traditionally valuable medicinal plant that has been commonly used in the traditional medicinal system and contributes to the native healthcare system in various parts of the world. This plant is renowned for its antibacterial and anticancer effects and its usage in the treatment of jaundice, diabetes, hypertension, and polio. All of the economically and medicinally essential plant parts of this species are used in the preparation of a potent cathartic. This review focused on and intended to highlight the most current knowledge about A. cathartica, including its important ethnomedicinal, modern medicinal, and phytochemical potential along with its green approaches. This plant has been extensively used in herbal medicine and has various important phytopharmacological properties. The modern green technological approaches of this plant enhance agricultural productivity when its various nanoparticles are applied in fields that perform antimicrobial, antipathogenic activities. Nanoparticles serve as carriers for the delivery of drugs and as disease targets in contemporary medicine. This plant has recently been involved in modern medicine as a threat to cancer, which is a significant accomplishment for modern medical science. Hence, A. cathartica is an important plant that can be useful to cure various ailments and could be useful in modern science with its green approaches. We must further investigate this plant's bioactivities to determine the mode of action.","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"319 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135474027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}