生物活性呋喃香豆素“异欧前胡素”:在医学上的治疗重要性和药理活性

Dinesh Kumar Patel
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摘要

背景:植物及其衍生的植物化学物质通常被称为次生代谢物,作为治疗多种人类疾病和相关并发症的良好药物来源,已被用于医学。草药在现代医学中被用于治疗一些慢性疾病,包括癌症。香豆素类植物化学物质具有重要的药用价值,主要来源于植物,包括被子植物。香豆素具有多种生物活性,包括抗菌、抗菌、抗真菌、抗氧化、抗肿瘤、抗hiv、降压、抗凝、抗癌、抗病毒、抗炎、镇痛、抗糖尿病、抗抑郁等。方法:从不同的科学数据库中收集大量的科学数据,并进行分析,以了解异欧前胡素在医学上的生物学潜力。对Google、Google Scholar、PubMed和Scopus数据库进行检索和分析,了解异欧前胡素的药性和治疗潜力。本文通过对不同科研工作的科学数据分析,探讨了异欧前胡素的治疗潜力。本文分析了异欧前胡素的药理活性,以了解异欧前胡素对人体各种疾病的有益保健作用。结果:不同研究工作的科学数据分析揭示了异欧前胡素在医学上的治疗潜力。异欧前胡素是在白芷中发现的香豆素类植物化学物质。异欧前胡素主要因其抗氧化、抗炎、抗细胞凋亡的作用而在医学上显示出巨大的治疗潜力,但其在乳腺癌中的生物学潜力及其光敏作用也在本文中进行了讨论。分析数据表明异欧前胡素存在于不同的药用植物中。结论:本研究显示了异欧前胡素在医学上的重要生物学意义和治疗潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bioactive Furanocoumarin ‘Alloimperatorin’: Therapeutic Importance and Pharmacological Activities in Medicine
Background: Plants and their derived phytochemicals commonly called secondary metabolites have been used in medicine as a good source of medicine for the treatment of numerous kinds of human disorders and associated complications. Herbal medicines have been used in modern medicine for the treatment of some chronic disorders, including cancer. Coumarins class phytochemicals are important in medicine and mainly derived from plant sources, including Angiosperms. Coumarins have numerous biological activities including antimicrobial, antibacterial, antifungal, antioxidant, antitumor, anti-HIV, antihypertension, anticoagulant, anticancer, antiviral, anti-inflammatory, analgesics, antidiabetic, and anti-depressive. Methods: Here in the present work, numerous scientific data were collected from different scientific databases and analyzed in order to know the biological potential of alloimperatorin in medicine. Google, Google Scholar, PubMed, and Scopus databases were searched and analyzed to know the medicinal properties and therapeutic potential of alloimperatorin. Therapeutic potential of alloimperatorin was investigated in the present work through scientific data analysis of different scientific research work. Pharmacological activities of alloimperatorin were analyzed in the present work to know the beneficial health aspects of alloimperatorin against various forms of human disorders. Results: Scientific data analysis of different research work revealed the therapeutic potential of alloimperatorin in medicine. Alloimperatorin is a coumarin class phytochemical found in the Angelica dahurica. Alloimperatorin revealed significant therapeutic potential in medicine mainly due to its anti-oxidative, anti-inflammatory, anti-apoptotic potential, however its biological potential in breast cancer and their photosensitization effect were also discussed in the present work. Analytical data signified the presence of alloimperatorin in different medicinal plants. Conclusion: Present work signified the biological importance and therapeutic potential of alloimperatorin in medicine.
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