Current Indian Science最新文献

Medicinal Value of Mushroom: A Deeper Insight 蘑菇的药用价值：深入了解

Current Indian Science Pub Date : 2024-07-24 DOI: 10.2174/012210299x285895240521042601

Krishna Gupta, Masne Tejaswini, M. Umekar

{"title":"Medicinal Value of Mushroom: A Deeper Insight","authors":"Krishna Gupta, Masne Tejaswini, M. Umekar","doi":"10.2174/012210299x285895240521042601","DOIUrl":"https://doi.org/10.2174/012210299x285895240521042601","url":null,"abstract":"\u0000\u0000Fungi are widely acknowledged as one of the most diverse and ecologically significant organisms with substantial economic importance on Earth.\u0000Edible and medicinal mushrooms have been recognized by human societies since ancient times, serving not only as valuable sources of\u0000nourishment but also as medicinal agents. The primary objective of this study is to explore the fruiting bodies of edible mushrooms and assess their\u0000capacity to serve as reservoirs of bioactive metabolites with pharmaceutical potential. The extensive analysis conducted aimed to elucidate the\u0000significant potential of these medicinal mushrooms, comparable to that of plants, in producing valuable bioactive compounds, thereby positioning\u0000them as abundant reservoirs for pharmaceutical compounds.\u0000\u0000\u0000\u0000Fungi produce many different bioactive compounds of different molecular weights, including lectins, lipids, peptidoglycans, phenols, polyketides,\u0000polysaccharides, proteins, polysaccharide-protein/peptide complexes, ribosomal and non-ribosomal peptides, steroids, terpenoids, and others.\u0000These compounds have more than 130 different therapeutic properties, such as analgesic, antimicrobial, antifungal, anti-inflammatory, anti-plaque,\u0000antiviral, cytotoxic, hepatoprotective, cholesterol-lowering, blood-sugar-lowering, blood-pressure-lowering, immune system, response system\u0000modulation, immune suppression, cell growth stimulation or regeneration, and more. Several bioactive polysaccharides or polysaccharide-protein\u0000complexes identified in these medicinal mushrooms seem to augment both innate and cell-mediated immune responses. Furthermore, these\u0000compounds display anti-tumor properties in both animal models and humans.\u0000","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"48 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141808260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FDA Approval of Zituvio for Type 2 Diabetes 美国食品和药物管理局（FDA）批准将齐都维用于治疗 2 型糖尿病

Current Indian Science Pub Date : 2024-07-24 DOI: 10.2174/012210299x286824240722042737

Abishek V, Muskan, Saurabh Srivastava, Pbn Prasad, Sandeep Kumar

引用次数: 0

Superhydrophobic Stainless Steel Mesh through Chemical Vapour Deposition ofTMCS for Effective Oil-Water Separation 通过化学气相沉积 TMCS 实现超疏水不锈钢网的有效油水分离

Current Indian Science Pub Date : 2024-07-22 DOI: 10.2174/012210299x306942240711105604

S. Latthe, Akshay R. Jundle, Prashant Yadav, Chandrakant Patil, U. Mote, Rajaram S. Sutar, Shanhu Liu

{"title":"Superhydrophobic Stainless Steel Mesh through Chemical Vapour Deposition of\u0000TMCS for Effective Oil-Water Separation","authors":"S. Latthe, Akshay R. Jundle, Prashant Yadav, Chandrakant Patil, U. Mote, Rajaram S. Sutar, Shanhu Liu","doi":"10.2174/012210299x306942240711105604","DOIUrl":"https://doi.org/10.2174/012210299x306942240711105604","url":null,"abstract":"\u0000\u0000To Fabricate the superhydrophobic Stainless Steel (SS) mesh using Trimethylchlorosilane (TMCS) through a Chemical Vapor Deposition (CVD)\u0000method for the oil-water mixture separation\u0000\u0000\u0000\u0000The frequent oil spills have a devastating impact on marine ecosystems and the environment. The porous materials with superhydrophobic\u0000properties have been created to separate oil and water effectively. Due to their ability to effectively separate oil and water, superhydrophobic\u0000coatings have gained significant attention.\u0000\u0000\u0000\u0000The cleaned stainless-steel mesh was put on a stand and covered with a glass container. Within the container, 50 mL of hexane, which contained 1\u0000mL of TMCS, was added. The mesh was then left for 3 h to undergo the CVD process\u0000\u0000\u0000\u0000The silane content with low surface energy creates a highly rough structure on the mesh surface. The optimal mesh coating is superhydrophobic,\u0000having a strong affinity to oil and a water contact angle of 162 ± 2°. The coated mesh has shown a separation efficiency of over 97.8% for different\u0000oil-water mixtures. The coatings sustain their superhydrophobicity up to 30 tape peels and 40 times sandpaper abrasion, indicating good\u0000mechanical durability.\u0000\u0000\u0000\u0000The study concludes that the S-3 sample is mechanically stable and can withstand various tests such as adhesive tape peeling, sandpaper abrasion,\u0000bending, folding, and twisting. It efficiently separates oil and water mixtures on a large scale with high efficacy\u0000","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"34 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141816613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advances in Heterogeneously Catalyzed Acceptorless Dehydrogenationof Alcohols to Carbonyl Derivatives and N-heterocyclic Compounds 异构催化无受体醇类脱氢生成羰基衍生物和 N-杂环化合物的最新进展

Current Indian Science Pub Date : 2024-07-22 DOI: 10.2174/012210299x318258240710090746

Krisangi Bordoloi, Jyotishma Baruah, Bibekananda Gogoi, Pankaj Das

{"title":"Recent Advances in Heterogeneously Catalyzed Acceptorless Dehydrogenation\u0000of Alcohols to Carbonyl Derivatives and N-heterocyclic Compounds","authors":"Krisangi Bordoloi, Jyotishma Baruah, Bibekananda Gogoi, Pankaj Das","doi":"10.2174/012210299x318258240710090746","DOIUrl":"https://doi.org/10.2174/012210299x318258240710090746","url":null,"abstract":"\u0000\u0000Oxidation of alcohols in an oxidant-free condition, commonly known as the acceptorless dehydrogenation (AD) reaction, has recently emerged as\u0000one of the widely used processes in synthetic organic chemistry. Alcohol acts as an excellent chemical precursor that produces a variety of\u0000dehydrogenated value-added products such as carbonyls, acids, acetals, and several coupling products, followed by the concomitant evolution of\u0000molecular hydrogen gas. AD reaction of alcohol, therefore, can be considered as a vital reaction for the hydrogen economy using alcohols as a\u0000liquid hydrogen carrier. Over the past decade, the growing importance of AD reactions has set the way for the continuous development of various\u0000homogeneous and heterogeneous catalytic systems. With the advantage of reusability and recyclability, heterogeneous catalysts have now become\u0000more promising and significant in the catalytic domain. This review aims to make an overview of the transition metal-based heterogeneous\u0000catalytic system of acceptorless alcohol dehydrogenation reaction reported till December, 2023.\u0000","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"31 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141816952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What are Proteome Atlases good for? 蛋白质组图谱有什么用？

Current Indian Science Pub Date : 2024-07-22 DOI: 10.2174/012210299x320402240715065917

Amit Kumar Yadav, Suruchi Aggarwal

引用次数: 0

Role of Omega-3PUFA: A Nutraceutical for Brain Functioning and Treatmentof Mental Disorders 欧米茄-3PUFA 的作用：提高大脑功能和治疗精神疾病的保健品

Current Indian Science Pub Date : 2023-12-14 DOI: 10.2174/012210299x255340231115095951

Ishu Garg, Raj Kumari, Meenakshi Sharma

{"title":"Role of Omega-3PUFA: A Nutraceutical for Brain Functioning and Treatment\u0000of Mental Disorders","authors":"Ishu Garg, Raj Kumari, Meenakshi Sharma","doi":"10.2174/012210299x255340231115095951","DOIUrl":"https://doi.org/10.2174/012210299x255340231115095951","url":null,"abstract":"\u0000\u0000Concerning the past few years in terms of health and nature, the globe has witnessed an upsurge in the use of nutraceuticals and nutritional and\u0000natural products in therapeutics. The major reason for this step is the conventional pharmacological treatment using synthetic drugs that do not\u0000meet the status of health and therapeutic requirements for various pathological conditions. Nutraceuticals promise prominent health and therapeutic\u0000benefits with no adverse or side effects, providing extra health benefits besides their action in any defined pathological condition. Nutraceuticals\u0000are extensive biological therapies that include herbs, vitamins, fatty acids, prebiotics, and probiotics used to promote and maintain health to prevent\u0000and cure pathological conditions, malignant processes, syndromes, and symptoms. Nutraceuticals have multidirectional therapeutic benefits and are\u0000claimed to be effective products in aiding human health. The addition of omega-3 for the treatment of mental and mood disorders was found to\u0000have safer, more valuable, and better therapeutic results in comparison to the use of synthetic drugs. Omega-3 is available in the regular diet\u0000through soybeans, walnuts, codfish, and salmon fish, and its constituents have been found to play a promising role in brain development, including\u0000brain aging and neurodegenerative disorders, in the pathology of mental and mood disorders, and treatment of the same. Supplementation with\u0000Omega-3 PUFA provides a promising effect in better brain development, treatment, prevention and cure of mental and mood disorders. This\u0000review endeavours to display and assert the clinical relevance of omega-3 PUFA in brain development, pathology, and treatment of mental and\u0000mood disorders.\u0000","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"22 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138972770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Record of Two Medicinal Plants, Exallage Auricularia and GomphostemmaOvatum, from Ultapani Reserve Forest, Northeast India 印度东北部乌尔塔帕尼保护区森林中的两种药用植物--Exallage Auricularia 和 GomphostemmaOvatum 的新记录

Current Indian Science Pub Date : 2023-12-14 DOI: 10.2174/012210299x277042231210055856

Gouri Rani Baglary, Twinkle Basumatary, Anuck Islary, Santosh Kumar

{"title":"New Record of Two Medicinal Plants, Exallage Auricularia and Gomphostemma\u0000Ovatum, from Ultapani Reserve Forest, Northeast India","authors":"Gouri Rani Baglary, Twinkle Basumatary, Anuck Islary, Santosh Kumar","doi":"10.2174/012210299x277042231210055856","DOIUrl":"https://doi.org/10.2174/012210299x277042231210055856","url":null,"abstract":"\u0000\u0000This report discusses two medicinal plants, namely Exallage auricularia (L.) Bremek from Rubiaceae family and Gomphostemma ovatum Wall\u0000from Lamiaceae family from Ultapani Reserve Forest of Bodoland Territorial Region (BTR) of Assam, India, are recorded, described, and\u0000identified based on their morphological characters, taxonomical notes, phenology, and field photos along with map of distribution.\u0000\u0000\u0000\u0000The local Bodo-trib of Assam used leaf paste of E. auricularia to cure jaundice and piles and G. ovatum for treatment of different ailments like flu,\u0000cough, cold, skin irritations, symptoms of indigestion, jaundice, etc.\u0000\u0000\u0000\u0000Inflorescence - verticillaster inflorescence in leaf axil, 3 to many flowers, 2 to 5 cm long. Flowers are born in opposite cymes, subtended by bracts,\u0000easily indistinguishable from leaves, and the arrangement of flowers is congested or lax. Bracts - leaf-like small cluster, subtending cyme,\u0000involucral bracts, stellate hairs, large bracteoles exceeding the calyx.\u0000\u0000\u0000\u0000G. ovatum is a perennial plant that can grow up to around 1.5 m tall and has tuber-like roots with infrequent node-level rooting.\u0000","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"19 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138972323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

“2D, 3D QSAR and Pharmacophore Identification of Thieno[3,2-d]pyrimidinesas Cholesterol inhibitors.” "噻吩并[3,2-d]嘧啶胆固醇抑制剂的二维、三维 QSAR 和药理鉴定"。

Current Indian Science Pub Date : 2023-12-13 DOI: 10.2174/012210299x244559231116105210

Rakesh Devidas Amrutkar, Kishor S. Jain

引用次数: 0

To Shed Light on the Association between Poor Ergophthalmologic Practicesand Computer Vision Syndrome 揭示不良用眼习惯与电脑视觉综合症之间的联系

Current Indian Science Pub Date : 2023-12-13 DOI: 10.2174/012210299x247199231128100613

Dakshita Hardatt, Gurvinder Singh, Navneet Kaur, akash j pethekar, Sumeet Gupta, Meenakshi Dhanawat

{"title":"To Shed Light on the Association between Poor Ergophthalmologic Practices\u0000and Computer Vision Syndrome","authors":"Dakshita Hardatt, Gurvinder Singh, Navneet Kaur, akash j pethekar, Sumeet Gupta, Meenakshi Dhanawat","doi":"10.2174/012210299x247199231128100613","DOIUrl":"https://doi.org/10.2174/012210299x247199231128100613","url":null,"abstract":"\u0000\u0000Computers play a vital role in people's lives because of their great precision, speed, and accuracy, as well as their ability to provide timely updates.\u0000A cascade of ocular and extraocular symptoms in computers or electronics leads to Computer Vision Syndrome. Ergonomics is the science of\u0000fitting job demands and workplace environments to the capabilities of the population. The use of a computer increases the risk of musculoskeletal\u0000issues, particularly in the upper extremities.\u0000\u0000\u0000\u0000The following research article elaborates on the surveys that were carried out in Maharishi Markandeshwar Deemed to be University Mullana, with\u0000701 participants. Data were collected using the computer vision syndrome questionnaire and the ergonomics questionnaire for a duration of 6\u0000months.\u0000\u0000\u0000\u0000The most prevalent symptom of CVS occasionally was found to be a headache (503 participants=71.7%), followed by eye heaviness and eye pain\u0000(483 participants=68.9%), burning sensation, itching and tearing (414 participants=59%), red eyes (361 participants=51.4%), foreign bodies (319\u0000participants=45.5%), dryness (281 participants=40%), blurred and double vision (266 participants=37.9%), increased sensitivity to light and\u0000colored halos (249 participants=35.5%), and difficulty focusing (299 participants=42.6%).\u0000\u0000\u0000\u0000All symptoms of CVS suffered by the participants were on an occasional basis, constituting the majority and the most common CVS symptom as\u0000headache. In assessing the ergonomics, all participants experienced pain at least in one extremity and the majority of participants had their back\u0000bent while working with electronics.\u0000","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139005637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Exhaustive Review on Recent Trends in Analytical Methods: DevelopmentStrategies and Recent Applications 分析方法最新趋势综述：发展战略和最新应用

Current Indian Science Pub Date : 2023-12-13 DOI: 10.2174/012210299x246468231115051717

Tanu Chaudhary, Akshay Kumar, N. Raj, GS Sarma, Shubham Dawange, Dilpreet Singh

{"title":"An Exhaustive Review on Recent Trends in Analytical Methods: Development\u0000Strategies and Recent Applications","authors":"Tanu Chaudhary, Akshay Kumar, N. Raj, GS Sarma, Shubham Dawange, Dilpreet Singh","doi":"10.2174/012210299x246468231115051717","DOIUrl":"https://doi.org/10.2174/012210299x246468231115051717","url":null,"abstract":"\u0000\u0000API analysis plays an important role in nourishing the quality, safety, efficacy, and potency of bulk drugs and pharmaceutical formulations.\u0000Increased drug products in the market lead to increased demand for new analytical techniques for Active Pharmaceutical Ingredient (API) analysis.\u0000During the past decades, method developments were necessitated for drug impurities, excipient profiling, and testing for biopharmaceuticals like\u0000dissolution and bioavailability. Moreover, advancements in the pharmaceutical industries necessitate upgrading newer technologies like analytical\u0000Quality by Design (QbD) and artificial intelligence. This review focused on analytical method development and its official guidelines provided by\u0000various regulatory bodies including ICH, US-FDA, AOAC, and USP. Moreover, this present art also states various validation and system\u0000parameters along with their applicability and recommended range. The critical appraisal of analytical technologies for performing various API\u0000analyses was also written in a scientific manner. Moreover, applications in recent trends in pharmaceutical industries as well as research were also\u0000documented. Hence, this review provides sufficient information for the readers for in-depth information starting from scratch to higher\u0000technologies for developing analytical methods and recent trends in the pharmaceutical industry.\u0000","PeriodicalId":479738,"journal":{"name":"Current Indian Science","volume":"103 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139004559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0