Nikki Kasal, Samantha A Devlin, Eleanor E Friedman, Kelly Ducheny, Gabriella Mulder, Amy K Johnson, Jessica P Ridgway
{"title":"Improving Provider Knowledge and Confidence With HIV Pre-exposure Prophylaxis (PrEP) Prescribing for Black Women: Evaluation of a Synchronous Training Module.","authors":"Nikki Kasal, Samantha A Devlin, Eleanor E Friedman, Kelly Ducheny, Gabriella Mulder, Amy K Johnson, Jessica P Ridgway","doi":"10.1521/aeap.2026.38.5.366","DOIUrl":"10.1521/aeap.2026.38.5.366","url":null,"abstract":"<p><p>HIV pre-exposure prophylaxis (PrEP) use among cisgender women, particularly Black women, remains low in the United States, partly due to limited provider comfort prescribing PrEP. This study evaluated a culturally tailored educational training designed to improve provider knowledge and confidence in prescribing PrEP to Black women at federally qualified health centers. From January 2024 to April 2025, interactive Zoom trainings were conducted at 11 sites in Florida and Illinois. Pre- and post-training assessments measured objective knowledge and self-rated attitudes toward PrEP prescribing. Changes were analyzed using odds ratios (ORs) and 95% confidence intervals (CIs). Among 138 participants, approximately half were physicians <i>(n</i> = 44, 47%) and one-quarter nurse practitioners (<i>n</i> = 25, 27%). Post-training, correct responses increased for 4/11 knowledge items (OR = 3.03-4.34), while comfort and ability to discuss PrEP with Black women increased across all five related items (OR = 2.86-6.41). This culturally tailored training improved provider knowledge and confidence, potentially advancing PrEP equity.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 5","pages":"366-384"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Pablo Zapata, Alyssa N Gorkin, Jessica Liao, Alithia Zamantakis, Rana Saber, Jessica Lee Schleider, Brian Mustanski
{"title":"An Adapted Intervention Mapping Approach to Scaling Digital HIV Care Through Single-Session Design.","authors":"Juan Pablo Zapata, Alyssa N Gorkin, Jessica Liao, Alithia Zamantakis, Rana Saber, Jessica Lee Schleider, Brian Mustanski","doi":"10.1521/aeap.2026.38.5.347","DOIUrl":"https://doi.org/10.1521/aeap.2026.38.5.347","url":null,"abstract":"<p><p>Digital health interventions (DHIs) for HIV prevention have demonstrated feasibility, acceptability, and, to a lesser extent, efficacy, but few have achieved widespread dissemination. We used intervention mapping and single-session design principles to adapt Keep It Up! (KIU!), a CDC-designated best-evidence HIV prevention program originally delivered over 6 months, into a single-session intervention, Keep It Brief! A 13-member expert and community advisory board guided six adaptation steps, prioritizing behavioral outcomes, objectives, and KIU!'s core theoretical determinants. The resulting intervention includes a universal HIV module, a tailored PrEP module based on users' PrEP experience, and a relationship module for participants who are single, monogamous, or in open/polyamorous relationships. Usability testing with 15 end users demonstrated high acceptability, engagement, and usability. Findings suggest that adapting multisession DHIs into single-session formats can preserve core intervention mechanisms while improving reach to populations and settings where multisession delivery is infeasible. We provide recommendations for future adaptation.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 5","pages":"347-365"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ben Chen, Zhongfang Yang, Yue Zhang, Shuyu Han, Xiang Qi, Jing Wang, Zhijing Xu, Weiyu Mao, Yaguang Zheng, Hongli Yang, Beibei Gong, Yanfen Fu, Yirong Shi, Bei Wu, Lin Zhang, Yan Hu
{"title":"Development of HOPES Intervention for a Randomized Controlled Trial to Reduce the Perceived Stigma Among Women Living With HIV/AIDS in China.","authors":"Ben Chen, Zhongfang Yang, Yue Zhang, Shuyu Han, Xiang Qi, Jing Wang, Zhijing Xu, Weiyu Mao, Yaguang Zheng, Hongli Yang, Beibei Gong, Yanfen Fu, Yirong Shi, Bei Wu, Lin Zhang, Yan Hu","doi":"10.1521/aeap.2026.38.5.436","DOIUrl":"10.1521/aeap.2026.38.5.436","url":null,"abstract":"<p><p>We developed and pilot-tested HOPES, the first theory-driven, culturally grounded mHealth program to reduce HIV-related stigma among Chinese women living with HIV/AIDS (WLWHA). Guided by the updated MRC framework, we synthesized a scoping review, 30 phenomenological interviews and multidisciplinary consultations, then co-created 12 weekly microdramas with 32 WLWHA from Yunnan/Henan that embed cultural motifs of face, family honor, and collectivism; content was delivered through an encrypted WeChat mini-program underpinned by narrative transportation and sexual script theories. In a two-stage, multicenter, prospective nonrandomized controlled pre-post clinical trial, participants demonstrated high engagement with the content. Qualitative feedback indicated strong cultural resonance and the acquisition of coping strategies. The intervention was associated with reductions in perceived stigma and improvements in coping self-efficacy, social support, and emotional well-being.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 5","pages":"436-449"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qingyang Li, Hui Liu, Yaodong Gu, Hao Zhang, Cheuk Chi Tam, Xiaoming Li, Qiyu Zhu, Mengjie Han, Xueying Yang
{"title":"Different HIV Testing Modalities and Associated Factors Among College Students Who Are Men Who Have Sex With Men in China.","authors":"Qingyang Li, Hui Liu, Yaodong Gu, Hao Zhang, Cheuk Chi Tam, Xiaoming Li, Qiyu Zhu, Mengjie Han, Xueying Yang","doi":"10.1521/aeap.2026.38.5.420","DOIUrl":"https://doi.org/10.1521/aeap.2026.38.5.420","url":null,"abstract":"<p><p>Men who have sex with men college students in China face a high risk of HIV infection, yet evidence comparing uptake of different HIV testing modalities remains limited. Using data from three national cross-sectional surveys conducted between 2021 and 2023 among college students from 151 universities in 14 provinces, we examined HIV testing behaviors and associated factors among this population. Among 1,567 participants, 62.0% had ever tested for HIV, with self-testing more commonly reported than facility-based testing. Across testing modalities, recreational drug use during sexual activity, lack of awareness of post-exposure prophylaxis, and absence of a regular sexual partner were associated with lower odds of HIV testing. Self-testing was more common among students engaged in commercial sex, whereas facility-based testing was more likely among older students and those unwilling to use post-exposure prophylaxis. These findings highlight key behavioral gaps and underscore the need for targeted HIV prevention to improve testing uptake.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 5","pages":"420-435"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katalia Alexander, David Gitagno, Anna Minja, Isaac Lema, Rachel Jared Mtei, Alyssa Martinez, Eric van Praag, Sylvia Kaaya, Joy Noel Baumgartner
{"title":"\"I Just Tested So That I Know My Health Status\": HIV Testing Motivations and Decision-Making Among Adolescents in Tanzania.","authors":"Katalia Alexander, David Gitagno, Anna Minja, Isaac Lema, Rachel Jared Mtei, Alyssa Martinez, Eric van Praag, Sylvia Kaaya, Joy Noel Baumgartner","doi":"10.1521/aeap.2026.38.5.403","DOIUrl":"https://doi.org/10.1521/aeap.2026.38.5.403","url":null,"abstract":"<p><p>Tanzanian adolescents are vulnerable to HIV and national policy supports HIV testing services (HTS), yet HTS is underutilized by adolescents. This qualitative study explores factors that influence the attitudes and decision-making of Tanzanian adolescents regarding HTS uptake. The VITAA clinical trial tested a school-clinic partnership that offered health check-ups for Tanzanian adolescents with optional HTS. Semistructured interviews <i>(n</i> = 35) were conducted with adolescents (mean age 16) from the VITAA cohort. Thematic qualitative analysis was informed by the Health Belief Model. Most adolescents reported having experienced HTS and the majority of those who tested received HTS at a preventative health care visit. Reasons for testing included wanting to know their health status. Motivations to test outside of routine health care included perceived behavioral risk of infection or close exposure to someone living with HIV. The main reason for not testing was low perceived risk. Many adolescents would test if their risk changed.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 5","pages":"403-419"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuhang Qian, Zuo-Feng Zhang, Warren Scott Comulada, Marco A Hidalgo, Sung-Jae Lee, M Reuel Friedman, Frank J Palella, Michael W Plankey, Gypsyamber D'Souza, Roger Detels, Matthew J Mimiaga
{"title":"Longitudinal Risk Factors for Incident Lung Cancer Among a Mixed HIV Serostatus Cohort of Sexual Minority Men in the United States.","authors":"Yuhang Qian, Zuo-Feng Zhang, Warren Scott Comulada, Marco A Hidalgo, Sung-Jae Lee, M Reuel Friedman, Frank J Palella, Michael W Plankey, Gypsyamber D'Souza, Roger Detels, Matthew J Mimiaga","doi":"10.1521/aeap.2026.38.5.385","DOIUrl":"10.1521/aeap.2026.38.5.385","url":null,"abstract":"<p><p>To examine how the co-occurrence of behavioral and psychosocial factors (depression, cigarette smoking, heavy alcohol use, and polydrug use) is associated with lung cancer incidence, we included 3,554 sexual minority men (SMM) from the Multicenter AIDS Cohort Study (MACS), 1996-2022, with assessments every 6 months. We used Cox proportional hazards models to examine the cumulative relationships of these factors with lung cancer incidence. We identified a positive dose-response relationship between the number of these factors and lung cancer incidence. Compared to men with no factors, those with two (aHR= 3.80, 95% Cl [1.46, 9.86]) and three or more (aHR = 8.33, 95% Cl [2.20, 31.60]) had increased lungcancer risk. Men living with HIV were more affected by these factors than men without HIV. Our findings highlight the need for prevention and treatment for depression and substance use when assessing lung cancer risk among SMM, which may inform strategies to reduce lung cancer incidence.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 5","pages":"385-402"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13676826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omphile Rashope, Marion Stevens, Samantha Willan, Zoe Duby, Kim Jonas, Pinky Mahlangu, Jill Hanass-Hancock
{"title":"Understanding the Relationship Between Intimate Partner Violence and HIV Status Disclosure Across Health Care Settings in Eastern and Southern Africa: A Scoping Review.","authors":"Omphile Rashope, Marion Stevens, Samantha Willan, Zoe Duby, Kim Jonas, Pinky Mahlangu, Jill Hanass-Hancock","doi":"10.1521/aeap.2026.38.4.284","DOIUrl":"https://doi.org/10.1521/aeap.2026.38.4.284","url":null,"abstract":"<p><p>HIV status disclosure is an ethical obligation and, in some jurisdictions, a legal requirement that supports treatment adherence. In Eastern and Southern Africa (ESA), where intimate partner violence (IPV) is prevalent, disclosure may have harmful consequences. The objective of this scoping review was to map the relationship between IPV and HIV disclosure across health care settings in ESA. Following PRISMA-ScR guidelines, peer-reviewed English-language studies (2012-2024) were identified through EBSCOhost, PubMed, and Google Scholar using a SPICE-informed search strategy. Thirty-six quantitative, qualitative, and mixed-methods studies met the inclusion criteria and were analyzed thematically. Three themes emerged: factors influencing disclosure, including relationship dynamics and fear of violence; the positive and negative consequences of disclosure, particularly IPV; and the role of health care workers, whose limited IPV training tended to increase risk. Integrating IPV screening, safety planning, and gender-sensitive training into HIV counseling is essential to support safe, client-led disclosure.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 4","pages":"284-306"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philip M Glaessner, Ananya Gorrai, Amanda Rondinelli Ratigan, Gail Burack, Sneha Jacob, Patricia Whitley Williams, Roseanne Marone, Sunanda Gaur, Lawrence C Kleinman
{"title":"Assessing Overall and Mental/Emotional Health Among People Living With HIV/AIDS.","authors":"Philip M Glaessner, Ananya Gorrai, Amanda Rondinelli Ratigan, Gail Burack, Sneha Jacob, Patricia Whitley Williams, Roseanne Marone, Sunanda Gaur, Lawrence C Kleinman","doi":"10.1521/aeap.2026.38.4.307","DOIUrl":"https://doi.org/10.1521/aeap.2026.38.4.307","url":null,"abstract":"<p><p>To characterize the lived experience of persons living with HIV/AIDS (PLWHA) during the COVID-19 pandemic, we utilized an innovative survey to assess the experiences of 94 adult respondents receiving medical care and/or case management services from two Ryan White funded sites in New Brunswick, NJ, from May 2020 to November 2021. The Local Inventory of Needs and Knowledge-HIV (LINK-HIV) survey includes five indices and assesses overall and mental/emotional health of PLWHA. We demonstrate internal validity of the indices, describe relationships between indices and health outcomes, and characterize the health of this population. We identified specific unmet needs across the constructs of social determinants of health (SDOH) Needs, Stress due to unmet SDOH, Access to Healthcare, Stress due to COVID-19, and Person-Centered Primary Care. Respondents' self-reported health was suboptimal (47.8% reported better overall health, 40.4% reported better mental/emotional health), and associations were seen between responses to the five indices and self-reported health outcomes.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 4","pages":"307-323"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jarrod E Gant, James S Miller, Elizabeth G Franklin
{"title":"Knowledge, Culture, and Communication in HIV Prevention: A Mixed-Methods Study of Nurse Practitioners' Roles in Pre-exposure Prophylaxis (PrEP) Uptake in Rural and Underserved Areas.","authors":"Jarrod E Gant, James S Miller, Elizabeth G Franklin","doi":"10.1521/aeap.2026.38.4.335","DOIUrl":"https://doi.org/10.1521/aeap.2026.38.4.335","url":null,"abstract":"<p><p>HIV remains a critical global public health concern. While no cure exists, treatments like antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) effectively reduce transmission rates. However, PrEP uptake is low, especially in areas facing stigma and misinformation, such as the southern United States, where high HIV stigma further hinders compliance. This study examined PrEP-related knowledge, attitudes, and prescribing behaviors among 179 nurse practitioners (NPs) in one southeastern state. Results indicated significant gaps in PrEP knowledge. Qualitative interviews highlighted stigma rooted in religious and regional contexts and emphasized the need for better education and provider-patient communication. These findings confirm that providers with PrEP knowledge and tools to reduce stigma may foster an increase in PrEP uptake in high-need areas.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 4","pages":"335-346"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beth Bourdeau, Alicia T Bolton, Jonathan Van Nuys, Michelle Palomares, Erin Moore, Greg M Rebchook, Starley B Shade, Orlando O Harris, Kate Buchacz, Jesse O'Shea, Parya Saberi
{"title":"Development of a Layperson Injector Training for the Home-Based Administration of Long-Acting Injectable Antiretroviral Therapies for Persons With HIV.","authors":"Beth Bourdeau, Alicia T Bolton, Jonathan Van Nuys, Michelle Palomares, Erin Moore, Greg M Rebchook, Starley B Shade, Orlando O Harris, Kate Buchacz, Jesse O'Shea, Parya Saberi","doi":"10.1521/aeap.2026.38.4.253","DOIUrl":"10.1521/aeap.2026.38.4.253","url":null,"abstract":"<p><p>Long-acting injectable antiretroviral therapy (LAI-ART) has the potential to transform HIV treatment by improving adherence, reducing stigma, and expanding access through decentralized care. The INVITE-Home study evaluates home-based LAI-ART administration by trained nonmedical treatment buddies (TBYs) selected by people with HIV (PWH). This article describes the development of a TBY training curriculum guided by Adult Learning Theory and refined through iterative stakeholder input. The five-phase process included review of existing materials, qualitative interviews with clinicians, PWH, and TBYs <i>(n =</i> 50), curriculum development, community advisory panel feedback <i>(n =</i> 9), and final refinement. Stakeholders emphasized structured hands-on practice, multimodal learning resources, and accessible language to build technical skills and confidence. The resulting curriculum integrates synchronous and asynchronous learning tailored to diverse learning preferences. Home-based LAI-ART may enhance privacy, reduce clinic burden, and support equitable, person-centered HIV care while maintaining safe administration and clinical oversight.</p>","PeriodicalId":47801,"journal":{"name":"Aids Education and Prevention","volume":"38 4","pages":"253-270"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13521325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}