Journal of Maxillofacial & Oral Surgery最新文献

{"title":"Conscious Sedation with Ketamine-Dexmedetomidine Versus Midazolam-Pentazocine in Enhancing Minor Oral Surgery Experience: A Parallel Arm Randomized Clinical Trial.","authors":"Ramsesh Manohar Ram, Preethi Jothi, Saai Arun Sundar, M P Santhosh Kumar, M Senthilmurugan","doi":"10.1007/s12663-025-02630-0","DOIUrl":"https://doi.org/10.1007/s12663-025-02630-0","url":null,"abstract":"<p><strong>Introduction: </strong>Minor oral surgeries done under local anesthesia can be quite traumatic to the patient; thus, the use of conscious sedation can improve patient comfort, reduce stress levels, provide better pain management, smoother surgical experiences, and better recovery. Combinations of ketamine-dexmedetomidine and midazolam-pentazocine were used as conscious sedation regimens, and they have unique strengths and weaknesses. Evaluating the sedation effects of ketamine-dexmedetomidine versus midazolam-pentazocine in maxillofacial surgeries is crucial for refining anesthetic practices. Therefore, this study aimed to determine the ideal combination of pharmacological sedative regimens for enhancing conscious sedation among patients undergoing minor oral surgical procedures.</p><p><strong>Materials and methods: </strong>The current parallel arm trial was conducted at our institution from July 2024 to January 2025. The study consisted of 104 normotensive adults in the age range of 18-60 years who underwent minor oral surgeries under conscious sedation in the dental hospital. In this double-blinded trial, one group was given an intervention of Ketamine-Dexmedetomidine combination (Group I) and the other group was given a Midazolam-Pentazocine combination (Group II) before undergoing minor oral and maxillofacial surgical procedures. The vitals during the pre-anesthetic evaluation such as blood pressure (BP), oxygen saturation and heart rate, and electrocardiography (ECG) were assessed before the procedure. During the procedure, all vitals were monitored every 10 min. Pain was assessed every 10 min during the surgery using an emoji-based visual analog scale (VAS) and the sedation score was assessed every 10 min during the surgery by a modified Ramsay assessment scale. The data were tabulated and analyzed in SPSS software version 26.0. Independent samples '<i>t</i>' test was used to assess the differences between the groups for the blood pressure, heart rate, and pain levels. Mann-Whitney <i>U</i> test was used to assess the differences between the groups in sedation levels. The significance level was kept at less than 0.05.</p><p><strong>Results: </strong>There was no significant difference in age, weight, gender distribution, ASA grading, and duration of anesthesia between the groups. Group II had lower heart rate than Group I throughout the study period and the results were statistically significant. Group II had lower systolic arterial blood pressure than Group I throughout the study period. Although Group II had a comparatively lesser VAS score than Group I, the results were not statistically significant. There was a statistically significant difference in the sedation levels between the groups post-intervention with Group I exhibiting higher scores than Group II.</p><p><strong>Conclusion: </strong>The Ketamine-Dexmedetomidine drug combination provided more effective sedation initially, with less respiratory depression than the Mi","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"903-911"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracheoesophageal Fistula Closure with Interposition of the Sternothyroid Muscle: Technical Note.","authors":"Arsheed Hussain Hakeem, Novfa Iftikhar","doi":"10.1007/s12663-025-02698-8","DOIUrl":"https://doi.org/10.1007/s12663-025-02698-8","url":null,"abstract":"","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"912-913"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Lip Taping in Changing Maxillofacial Soft and Hard Tissue Dimensions in Cleft Patients: A Retrospective Cohort Study.","authors":"Akshita Bansal, Ruchi Singhal, Ritu Namdev, Deepika Kheriwal","doi":"10.1007/s12663-025-02596-z","DOIUrl":"https://doi.org/10.1007/s12663-025-02596-z","url":null,"abstract":"<p><strong>Objective: </strong>To measure the effectiveness of lip taping in changing maxillofacial soft and hard tissue dimensions in patients with unilateral complete cleft lip and palate (UCLP).</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Available photographs and maxillary casts of patients with unilateral cleft lip and palate who were treated with lip taping were assessed at three time intervals, at the beginning of the treatment (T1), just before primary lip repair surgery (T2) and eight weeks after lip surgery (T3).</p><p><strong>Participants: </strong>Twenty infants with unilateral complete cleft lip and palate.</p><p><strong>Main outcome measures: </strong>Various soft and hard tissue parameters were assessed at three time points.</p><p><strong>Results: </strong>The study found statistically significant difference (<i>p</i>-value < 0.001) at 95% confidence interval (CI) in all parameters pertaining to reduce the cleft gap and improve the nasal symmetry.</p><p><strong>Conclusions: </strong>Lip taping is a successful and inexpensive method of changing maxillofacial and nasoalveolar parameters before primary surgical lip repair in infants with unilateral complete cleft lip and palate.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"875-881"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148043829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Nasal Intubation Tube Design on Nasal Morphology in Orthognathic Surgery: a Comparative Study.","authors":"Merve Öztürk Muhtar, Sabahat Zeynep Yey Özkeskin, Yusuf Bekir Kara, Pelin Corman Dincer, Erol Cansız","doi":"10.1007/s12663-025-02702-1","DOIUrl":"https://doi.org/10.1007/s12663-025-02702-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study compared the effects of two different intubation tube designs used in orthognathic surgery on nasal morphology alterations, utilizing three-dimensional imaging.</p><p><strong>Methods: </strong>Three-dimensional facial scanning (3DFS) images obtained from 22 patients preoperatively (T0) and at six months postoperatively (T1) were retrospectively analyzed. The patients were categorized into two groups according to the type of the intubation tube used (Group I: Cuffed Reinforced Endotracheal Tube; Group II: North Polar Endotracheal Tube (Portex® North Polar tube)). Following the identification of reference anatomical landmarks, nasal soft tissue measurements were conducted.</p><p><strong>Results: </strong>In Group I, a significant difference in right nostril axis was found between T0 and T1 (<i>p</i> = 0,038). Intragroup analysis of the right and left Nasal-Alar (N-A) angles revealed significant changes between T0 and T1 measurements. At T1, the right N-A angles in Group I were significantly different from those in Group II (53.00 ± 4.77 vs. 48.72 ± 4.70, respectively; <i>p</i> = 0.047). The right-left nostril width difference was statistically greater in Group I compared to Group II at T1 (median values 154; 60, respectively).</p><p><strong>Conclusion: </strong>The design and material of the intubation tube should be considered a contributing factor that may influence the nasal morphology.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"713-721"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Clinico-Microbiological Comparison of Antibacterial-Coated and Non-coated Polyglactin 910 Sutures in Extraction Sockets: Prospective, Split-Mouth, Randomized, Triple-Blinded Study.","authors":"Amar Singh, Vandana Shenoy, Janani Ravindranath, Gayathri Gopi, Mohamed Afradh","doi":"10.1007/s12663-025-02595-0","DOIUrl":"https://doi.org/10.1007/s12663-025-02595-0","url":null,"abstract":"<p><strong>Introduction: </strong>Despite being a ubiquitous procedure in oral surgery, tooth extraction, including impacted third molars, carries the potential for postoperative complications such as suture site infections (SSIs). These SSIs occur with a frequency of approximately 5% and typically fall within the \"clean-contaminated\" surgical category, where triclosan-coated sutures have demonstrated a reduction in incidence. However, the intraoral environment presents a unique microbial landscape, raising the question of whether these benefits translate to the specific context of extraction sockets. Therefore, this investigation aims to conduct a comparative analysis, examining both clinical and microbiological aspects, to evaluate the antibacterial efficacy of plain polyglactin 910 sutures and triclosan-coated polyglactin 910 sutures in extraction sockets post-surgery.</p><p><strong>Material methods: </strong>Assessing effectiveness of triclosan sutures in reducing suture site infections, a split-mouth study was conducted with 111 patients undergoing multiple extractions (222 sites). Each patient received triclosan suture on one site and plain suture on the other. Suture handling, infection rates, pain levels, and healing were evaluated on days 3 and 7 post-extraction. Bacteria on the sutures were also identified and quantified.</p><p><strong>Results: </strong>The study found that triclosan-coated sutures significantly improved socket healing, reduced suture site infections (SSIs), and decreased bacterial colonization compared to plain polyglactin 910 sutures on day 3 when compared to day 7. The study suggests that triclosan's antibacterial properties reduce bacterial colonization on sutures, leading to improved clinical outcomes.</p><p><strong>Conclusion: </strong>This study demonstrates triclosan-coated sutures reduced infection and inflammation in dental extractions compared to conventional sutures, likely due to decreased bacterial colonization.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"857-865"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148043164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement in Survival Rates and Quality of Life Among Patients Surgically Treated for Squamous Cell Carcinoma of the Oral Cavity.","authors":"Giancarlo Tirelli, Enrico Zanelli, Jerry Polesel, Nicoletta Gardenal, Vittorio Ramella, Chiara Mineo, Simone Zucchini, Marco Piovesana, Vittorio Grill, Fabiola Giudici, Francesca Boscolo Nata, Alberto Marcuzzo, Paolo Boscolo-Rizzo","doi":"10.1007/s12663-024-02289-z","DOIUrl":"10.1007/s12663-024-02289-z","url":null,"abstract":"<p><strong>Purpose: </strong>The study aimed to assess if outcomes for oral squamous cell carcinoma (OSCC) patients have improved, and if so, whether these improvements correlate with changes in diagnostic and therapeutic methods over time.</p><p><strong>Methods: </strong>Retrospective study including patients surgically treated for OSCC between 2002 and 2020.</p><p><strong>Results: </strong>Among the 193 consecutive patients with primary OSCC who met the inclusion criteria (median age 66; 60.4% male), 80 (41.4%) were treated between 2002 and 2011, and 113 (58.6%) between 2011 and 2020. Multivariate analysis showed a significant improvement in overall survival rates from 2012 to 2020, compared with the period from 2002 to 2011 (HR for death, 0.33; 95% CI 0.17-0.67). Similar observations have emerged in progression-free and disease-specific survival. When stratified by stage, the improvement was found to be significant only for advanced stages. The use of NBI during both preoperative and operative setting as well as margin mapping significantly increased over the time. Both patients with early and advanced-stage OSCC treated between 2012 and 2020 exhibited improved pain scores.</p><p><strong>Conclusions: </strong>Despite the shift to less invasive surgeries, our analysis shows significant improvement over time, especially in advanced-stage diseases, highlighting the impact of evolving strategies on challenging cases.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"646-655"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer Burden, Mortality, and Survivorship Care in India.","authors":"Arshad Ayub, Adity Bansal, Srinivas Gosla Reddy, Saurabh Varshney","doi":"10.1007/s12663-025-02587-0","DOIUrl":"https://doi.org/10.1007/s12663-025-02587-0","url":null,"abstract":"<p><strong>Introduction: </strong>The cancer landscape in India is defined by a heavy burden of disease, stark mortality disparities, and significant gaps in survivorship care. Despite lower cancer incidence rates compared with high-income countries, the region experiences disproportionately high mortality rates due to late diagnoses, limited healthcare infrastructure, and widespread inequities in access to treatment.</p><p><strong>Purpose: </strong>Distinctive risk factors, such as tobacco use and infection-related malignancies, further intensify the burden. Survivorship care remains underdeveloped, with cultural stigmas and systemic barriers compounding the challenges faced by cancer survivors.</p><p><strong>Result: </strong>This review synthesizes the state of knowledge on cancer incidence, mortality, and survivorship care across India and other parts of Asia, presenting insights from epidemiological studies, projections, and qualitative data.</p><p><strong>Conclusion: </strong>Addressing these challenges will require an integrated, multidisciplinary approach that strengthens prevention, reduces morbidity and mortality, and improves survivorship outcomes tailored to regional realities.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"663-667"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148043869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orbital Exenteration for Primary Tumors or Secondary to Extension Among Hospital Patients: A Retrospective Case Study.","authors":"Kuauhyama Luna-Ortiz, Maria Del Rayo Chavez-Benitez, Zelik Luna-Peteuil, Dorian Y Garcia-Ortega","doi":"10.1007/s12663-024-02318-x","DOIUrl":"https://doi.org/10.1007/s12663-024-02318-x","url":null,"abstract":"<p><strong>Background: </strong>To describe the indications for orbital exenteration in our hospital, complications, and survival outcomes.</p><p><strong>Methods: </strong>A retrospective study of 117 patients who underwent orbital exenteration for primary tumors or tumors extending into the orbit. The study included cases from January 1, 2010, to December 31, 2022.</p><p><strong>Results: </strong>We included 96 patients who underwent orbital exenteration. Surgery was performed for primary orbital tumors in 60 patients. The primary sites of origin were the eyelids and conjunctiva, 27.1% and 28.1%, respectively. Adjuvant therapy was administered to 51 patients. The most common histologic type was squamous cell carcinoma (40.6%), followed by basal cell carcinoma (18.8%). Positive surgical margins were found in 41 patients. Recurrence occurred in 22 patients. Surgical margins and bone invasion were considered prognostic factors.</p><p><strong>Conclusion: </strong>Advanced tumors with bone invasion have a worse prognosis. Therefore, achieving negative margins is less likely. These patients experience a recurrence rate of 50%.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"760-766"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Spiritual Scalpel: Surgical Precision, Endurance, and Compassionate Practice Through Inner Wisdom.","authors":"Rishi Kumar Bali","doi":"10.1007/s12663-026-03079-5","DOIUrl":"https://doi.org/10.1007/s12663-026-03079-5","url":null,"abstract":"","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"635-637"},"PeriodicalIF":0.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Topical Hemocoagulase on the Healing of Surgical Wounds in the Neck: A Randomized Clinical Trial.","authors":"Dyna Albert, M R Muthusekhar","doi":"10.1007/s12663-025-02623-z","DOIUrl":"10.1007/s12663-025-02623-z","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the role and effectiveness of topical hemocoagulase in the healing process of surgical neck wounds in oral cancer patients undergoing surgery as the primary treatment modality.</p><p><strong>Methodology: </strong>This prospective, parallel, double-blinded randomized clinical trial was conducted on oral cancer patients planned for surgical resection and neck dissection. The study included 22 patients divided into two groups: Group I received topical hemocoagulase, and Group II served as the control. Quantitative assessment was performed using the DermaLab Combo device to measure dermal thickness, collagen level, elasticity, viscoelasticity, and retraction time. Qualitative assessment was performed using the Patient and Observer Scar Assessment Scale (POSAS).</p><p><strong>Results: </strong>Analysis of quantitative variables revealed a significant improvement in dermal thickness, collagen levels, elasticity, viscoelasticity, and retraction time in Group I compared to Group II at both the 1st and 4th postoperative weeks. Qualitative assessment using POSAS showed a notable reduction in pain and improved overall scar appearance in the hemocoagulase group. These findings are consistent with previous studies that have shown the effectiveness of hemocoagulase in enhancing wound healing and reducing scar formation.</p><p><strong>Conclusion: </strong>Topical hemocoagulase significantly enhances wound healing in surgical neck wounds of oral cancer patients, providing both quantitative improvements and higher patient satisfaction.</p>","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"25 3","pages":"895-902"},"PeriodicalIF":0.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13201663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148044125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}