{"title":"The severity of non-smoking chronic obstructive pulmonary disease is correlated with biomass fuel exposure and COPD assessment test score.","authors":"Anuj Kumar Pandey, Ajay Kumar Verma, Arpita Singh, Surya Kant, Shyam Chand Chaudhary, Jyoti Bajpai, Rakesh Kumar Dixit","doi":"10.4103/lungindia.lungindia_304_23","DOIUrl":"10.4103/lungindia.lungindia_304_23","url":null,"abstract":"<p><strong>Background and objective: </strong>Tobacco smoking is an established risk factor for chronic obstructive pulmonary disease (COPD). Current evidence suggests that non-tobacco-related risk factors vary geographically and are less understood than smoking. This study aims to compare the risk factors, symptoms, and clinical features of smoking (S-COPD) and non-smoking (NS-COPD) in a COPD population.</p><p><strong>Materials and methods: </strong>In this retrospective cross-sectional study, 489 COPD patients were screened. Data on socio-demographics, smoking and medical history, other risk factors, symptoms, and clinical characteristics including COPD Assessment Test (CAT) score, and Modified Medical Research Council (mMRC) Dyspnea Scale were examined.</p><p><strong>Results: </strong>Of the total selected 416 COPD patients, 35.34% were NS-COPD while 64.66% were S-COPD. S-COPD was predominant in males, whereas NS-COPD was predominant in females (P < 0.0001). In NS-COPD, biomass fuel exposure was a major risk factor (P < 0.0001), and 61% of subjects had a biomass fuel exposure index of >60. In bivariate and multivariate analyses, no risk factors were correlated with forced expiratory volume in 1 second (FEV1)% predicted, while among clinical features, duration of illness (P = 0.001) was correlated with lower values of FEV1 in the multivariate table of S-COPD. In the multivariate analysis, biomass fuel exposure (P = 0.039) and CAT score (P < 0.0001) were correlated with FEV1(%) in NS-COPD.</p><p><strong>Conclusion: </strong>Biomass fuel exposure is a substantial risk factor for NS-COPD and was correlated with FEV1(%) predicted. In addition, the CAT score correlated with disease severity in patients with NS-COPD. The development of COPD in non-smokers is being recognized as a separate phenotype and it should be managed according to risk factors.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"251-258"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2024-07-01Epub Date: 2024-06-28DOI: 10.4103/lungindia.lungindia_525_23
V Shrinath, S Vignesh, Somnath Pan, R Ananthakrishnan
{"title":"'You bleed in war and you bleed in peace: Hemoptysis in a case with retained intra-thoracic bullet fragments decades after the injury'.","authors":"V Shrinath, S Vignesh, Somnath Pan, R Ananthakrishnan","doi":"10.4103/lungindia.lungindia_525_23","DOIUrl":"10.4103/lungindia.lungindia_525_23","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"331-332"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2024-07-01Epub Date: 2024-06-28DOI: 10.4103/lungindia.lungindia_228_24
Himanshu Garg, Prerana Garg
{"title":"Shedding light on the prevalence of co-morbid insomnia and obstructive sleep apnoea.","authors":"Himanshu Garg, Prerana Garg","doi":"10.4103/lungindia.lungindia_228_24","DOIUrl":"10.4103/lungindia.lungindia_228_24","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"249-250"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of co-morbid insomnia and obstructive sleep apnoea.","authors":"Swapnil Manaji Thorve, Manish Yadav, Anjali Arvind Kamath, Jairaj Parmeswaran Nair","doi":"10.4103/lungindia.lungindia_555_23","DOIUrl":"10.4103/lungindia.lungindia_555_23","url":null,"abstract":"<p><strong>Introduction: </strong>The coexistence of insomnia and obstructive sleep apnea (OSA) poses a complex and challenging clinical scenario, commonly referred to as comorbid insomnia and OSA (COMISA). The bidirectional relationship between these two sleep disorders is explored, illuminating how the presence of one can exacerbate the severity and manifestations of the other. We under took this study to understand the prevalence of COMISA in Indians which is never studied.</p><p><strong>Aim: </strong>To study the prevalence of COMISA in tertiary hospital in India.</p><p><strong>Methods: </strong>All OSA patients diagnosed with polysomnography were interviewed with insomnia severity index. Patients having score of more than 15 were considered to have insomnia. Demographic factors, clinical and physical examination and polysomnography values were noted.</p><p><strong>Results: </strong>25% of 64 patients were diagnosed to have COMISA. Female gender, BMI, and STOP BANG score had positive association with COMISA, whereas age was not associated with increased risk.</p><p><strong>Conclusion: </strong>COMISA can be more complex to diagnose and manage than insomnia or OSA alone. The symptoms and mechanisms of each condition have synergistic effect and is a barrier to treating COMISA.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"272-277"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2024-07-01Epub Date: 2024-06-28DOI: 10.4103/lungindia.lungindia_461_23
Parthasarathi Bhattacharyya, Srijita Sen, Shuvam Ghosh
{"title":"Glycopyrronium inhalation, bronchodilator reversibility assessment, and defining asthma: A new paradigm.","authors":"Parthasarathi Bhattacharyya, Srijita Sen, Shuvam Ghosh","doi":"10.4103/lungindia.lungindia_461_23","DOIUrl":"10.4103/lungindia.lungindia_461_23","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"328-329"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A man with a right paratracheal mass and recurrent respiratory infections: Putting the pieces together.","authors":"Vipul Kumar Garg, Anand Vijay, Mayurakshi Das, Venkata Nagarjuna Maturu","doi":"10.4103/lungindia.lungindia_107_24","DOIUrl":"10.4103/lungindia.lungindia_107_24","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"320-321"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lung IndiaPub Date : 2024-07-01Epub Date: 2024-06-28DOI: 10.4103/lungindia.lungindia_454_23
Swapnil M Thorve, Manish Yadav, Amol S Shenurkar, Jairaj P Nair
{"title":"Shining a light on clofazimine: Unveiling crystal-laden macrophages in the bronchoalveolar lavage fluid of multidrug-resistant tuberculosis.","authors":"Swapnil M Thorve, Manish Yadav, Amol S Shenurkar, Jairaj P Nair","doi":"10.4103/lungindia.lungindia_454_23","DOIUrl":"10.4103/lungindia.lungindia_454_23","url":null,"abstract":"","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"318-319"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utility and safety of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TMC): A systematic review and meta-analysis.","authors":"Pranay Sai Chandragiri, Anshula Tayal, Saurabh Mittal, Neha Kawatra Madan, Pawan Tiwari, Vijay Hadda, Anant Mohan, Karan Madan","doi":"10.4103/lungindia.lungindia_606_23","DOIUrl":"10.4103/lungindia.lungindia_606_23","url":null,"abstract":"<p><strong>Background: </strong>Modalities to improve tissue acquisition during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) have been investigated. Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TMC) is a modality to obtain larger histological samples by inserting a cryoprobe into the mediastinal lesion. We aimed to study the diagnostic yield and safety of EBUS-TMC.</p><p><strong>Methods: </strong>We performed a systematic search of the PubMed and Embase databases to extract the relevant studies. We then performed a meta-analysis to calculate the diagnostic yield of EBUS-TMC and compare it with EBUS-TBNA.</p><p><strong>Results: </strong>Following a systematic search, we identified 14 relevant studies (869 patients undergoing EBUS-TMC and EBUS-TBNA). We then performed a meta-analysis of the diagnostic yield of EBUS-TMC and EBUS-TBNA from studies wherein both procedures were performed. The pooled diagnostic yield of EBUS-TMC was 92% (95% confidence interval [CI], 89%-95%). The pooled diagnostic yield of EBUS-TBNA was 81% (95% CI, 77%-85%). The risk difference in yield was 11% (95% CI, 6%-15%, I2 = 0%) when EBUS-TMC and EBUS-TBNA were compared. The only complication reported commonly with EBUS-TMC was minor bleeding. The complication rate was comparable with EBUS-TBNA.</p><p><strong>Conclusion: </strong>EBUS-TMC provides a greater diagnostic yield with a similar risk of adverse events compared to EBUS-TBNA. Future studies are required to clearly establish which patients are most likely to benefit from this modality.</p>","PeriodicalId":47462,"journal":{"name":"Lung India","volume":"41 4","pages":"288-298"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141477737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}