Ashley S Shirriff, Jordan N Cornwell, Justin N Karlin, Robert A Goldberg, Daniel B Rootman
{"title":"Investigating the correlation between the blepharospasm disability index and botulinum neurotoxin dosage for benign essential blepharospasm and hemifacial spasm.","authors":"Ashley S Shirriff, Jordan N Cornwell, Justin N Karlin, Robert A Goldberg, Daniel B Rootman","doi":"10.1080/01676830.2025.2551624","DOIUrl":"https://doi.org/10.1080/01676830.2025.2551624","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to evaluate the association between the blepharospasm disability index (BSDI) and botulinum neurotoxin (BTX) dosage for patients affected by either benign essential blepharospasm or hemifacial spasm.</p><p><strong>Methods: </strong>Cross-sectional cohort study evaluating adult patients diagnosed with benign essential blepharospasm or hemifacial spasm who completed a BSDI evaluation prior to receiving same-day therapeutic BTX injections. Primary outcome measures included BSDI score and number of BTX units. Simple and multivariable linear regression analyses were utilized to assess the relationship between BSDI score and BTX dosage.</p><p><strong>Results: </strong>For patients with benign essential blepharospasm, BTX dosage was significantly and positively correlated to BSDI score (R<sup>2</sup>=0.16, β=1.15, <i>p</i>=0.007). This relationship remained robust when controlling for age, sex, disease duration, interval since previous BTX injection, and injecting provider (β=1.11, <i>p</i>=0.010). No significant correlation was identified between BSDI score and BTX dosage for patients affected by hemifacial spasm (R<sup>2</sup>=0.05, β=0.39, <i>p</i>=0.379).</p><p><strong>Conclusions: </strong>This study demonstrates that BTX dosage is significantly and positively correlated to BSDI score for patients affected by benign essential blepharospasm, but not for those affected by hemifacial spasm. Incorporating BSDI score may support more individualized and efficient clinical management of benign essential blepharospasm.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-5"},"PeriodicalIF":0.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saleha Azeem, Shameer Iqbal Ghuman, Ishmal Fatima Shahid, Muhammad Imaz Bhatti, Jawad Ahmad, Zainab Jamil, Abeeha Fatima, Azka Ijaz, Eilaf Azeem, Muhammad Ahmad Tariq
{"title":"The use of tranexamic acid in external dacryocystorhinostomy: a systematic review and meta-analysis of randomized controlled trials.","authors":"Saleha Azeem, Shameer Iqbal Ghuman, Ishmal Fatima Shahid, Muhammad Imaz Bhatti, Jawad Ahmad, Zainab Jamil, Abeeha Fatima, Azka Ijaz, Eilaf Azeem, Muhammad Ahmad Tariq","doi":"10.1080/01676830.2025.2534963","DOIUrl":"https://doi.org/10.1080/01676830.2025.2534963","url":null,"abstract":"<p><strong>Purpose: </strong>Tranexamic acid (TXA) is an antifibrinolytic agent effective in reducing extensive blood loss and mortality. However, it lacks significant clinical evidence in peri-ocular procedures, including dacryocystorhinostomy (DCR). This study aims to assess the effectiveness of TXA in reducing intraoperative hemorrhage and improving surgical outcomes.</p><p><strong>Methods: </strong>We searched PubMed, Medline, ClinicalTrials.gov, and the Cochrane Library, along with grey literature sources from the year 2000 onwards for randomized controlled trials (RCTs). We used the revised Cochrane Risk of Bias tool (RoB 2.0) to assess quality. RevMan 5.4 was used to conduct all statistical analyses using a random-effects model.</p><p><strong>Results: </strong>A meta-analysis was performed on 448 patients from 5 RCTs. Between TXA and placebo group, a statistically significant reduction in intraoperative bleeding, a statistically non-significant reduction in total surgical time and recovery time, a statistically significant increase in surgeon satisfaction, and no statistically significant difference in anesthesia time were observed. A comparison of topical TXA with placebo in one study showed a statistically significant reduction in intraoperative bleeding and total surgical time. Between TXA and the other interventions, including remifentanil and hydralazine, no statistically significant differences in intraoperative bleeding, total surgical time, recovery time, surgeon satisfaction, and anesthesia time were observed.</p><p><strong>Conclusion: </strong>Evidence shows the superiority of TXA in reducing intraoperative bleeding and increasing surgeon satisfaction in patients undergoing DCR, improving surgical outcomes and recovery time. Further studies are needed to evaluate the effectiveness of TXA in ocular procedures.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-15"},"PeriodicalIF":0.8,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew J Lee, Daniel J Hu, Michael M Migliori, Philip R Rizzuto
{"title":"Assessing carbon emissions in oculoplastics: blepharoplasty practices in diverse surgical settings.","authors":"Matthew J Lee, Daniel J Hu, Michael M Migliori, Philip R Rizzuto","doi":"10.1080/01676830.2025.2549093","DOIUrl":"https://doi.org/10.1080/01676830.2025.2549093","url":null,"abstract":"<p><strong>Purpose: </strong>Climate change poses a significant threat to global public health, with the healthcare sector contributing substantially to greenhouse gas emissions. Ophthalmic surgeries, particularly in operating rooms (ORs), generate significant waste and carbon emissions. This study compares the environmental impact of a single bilateral upper lid blepharoplasty performed in a privately owned versus a hospital-based ambulatory surgery center (ASC).</p><p><strong>Methods: </strong>A material flow analysis and waste audit were conducted for blepharoplasty procedures performed between June and July 2024 in two surgical settings: a privately owned ASC and a hospital-based ASC. Surgical supply inventories and utility usage were recorded through direct observation and post-operative audits. A cradle-to-grave life cycle assessment (LCA), following ISO 14,040 standards, was used to evaluate environmental impact in kilograms of carbon dioxide equivalents (kg CO₂e). Impact equivalencies were calculated for context.</p><p><strong>Results: </strong>The hospital-based ASC generated 2,744.5 grams of waste per blepharoplasty versus 1,429.6 grams in the privately owned ASC - a 47.9% reduction. Carbon emissions were 9.7 kg CO₂e per case at the hospital-based ASC (equivalent to burning 12.1 pounds of coal), versus 5.0 kg CO₂e at the privately owned ASC (6.3 pounds of coal) - a 48.5% decrease.</p><p><strong>Conclusions: </strong>The hospital-based ASC produces more waste and emissions per blepharoplasty than the privately owned ASC.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-8"},"PeriodicalIF":0.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brendan K Tao, Faizan Naveed, Salem A Al-Burak, Kate Lim, Amir R Vosoughi, Kenneth Chang, Christian El-Hadad, Georges Nassrallah, Ahsen Hussain, Bryan Arthurs, Navdeep Nijhawan, Edsel B Ing
{"title":"Prevalence of phantom eye syndrome following eye removal: a systematic review and meta-analysis.","authors":"Brendan K Tao, Faizan Naveed, Salem A Al-Burak, Kate Lim, Amir R Vosoughi, Kenneth Chang, Christian El-Hadad, Georges Nassrallah, Ahsen Hussain, Bryan Arthurs, Navdeep Nijhawan, Edsel B Ing","doi":"10.1080/01676830.2025.2546549","DOIUrl":"https://doi.org/10.1080/01676830.2025.2546549","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the literature-pooled prevalence of phantom eye syndrome (PES) following eye removal, including phantom vision (PV), phantom pain (PP), or phantom non-visual non-painful (PNVNP) sensations.</p><p><strong>Methods: </strong>Databases were searched from inception to March 12 2025. A systematic review and meta-analysis of PES prevalence and risk factors was conducted.</p><p><strong>Results: </strong>Seven studies were identified (775 patients). The literature-pooled prevalence of PES, defined as having at least one constitutive symptom, was 58.9% (95% CI [50.4, 66.9], I<sup>2</sup> = 78%, five studies). The most common constitutive symptom was PV in 35.6% (95% CI [29.5, 42.3], I<sup>2</sup> = 71.1%, six studies), followed by PP in 26.4% (95% CI [20.8, 32.9], I<sup>2</sup> = 76.1%, seven studies) and PNVNP in 19.9% (95% CI [7.9, 42.0], I<sup>2</sup> = 91.2%, six studies) sensations. The pooled prevalence of reporting all three constitutive symptoms simultaneously was 4.8% (95% CI [2.2, 10.1], I<sup>2</sup> = 67.3%, three studies). Commonly reported risk factors in the literature included mental health comorbidities and preoperative pain, though some studies did not conduct multivariable analysis to control for confounding factors.</p><p><strong>Conclusions: </strong>Low certainty evidence supports that over 50% of patients may develop at least one constitutive PES symptom. Patients may benefit from PES screening, reassurance, and early treatment of postoperative pain.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-8"},"PeriodicalIF":0.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction.","authors":"","doi":"10.1080/01676830.2025.2550908","DOIUrl":"https://doi.org/10.1080/01676830.2025.2550908","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Troy Karanfilian, Moshe Isaac Weber, Anne Barmettler
{"title":"Pigmented basal cell carcinoma in a Black patient.","authors":"Troy Karanfilian, Moshe Isaac Weber, Anne Barmettler","doi":"10.1080/01676830.2025.2545401","DOIUrl":"https://doi.org/10.1080/01676830.2025.2545401","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144974025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient-specific implant: role in reconstruction of orbit and zygoma post-debridement for mucormycosis.","authors":"Sumer Doctor, Prerna Sinha, Tarjani Dave","doi":"10.1080/01676830.2025.2543387","DOIUrl":"https://doi.org/10.1080/01676830.2025.2543387","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.8,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vascular dynamics during <i>laissez-faire</i> healing in periocular defects assessed with laser speckle contrast imaging.","authors":"Johanna Vennström Berggren, Jens Nääv Ottosson, Kajsa Tenland, Magdalena Naumovska, Morgana Fontana, Aboma Merdasa, Malin Malmsjö","doi":"10.1080/01676830.2025.2545402","DOIUrl":"https://doi.org/10.1080/01676830.2025.2545402","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the role of blood perfusion and revascularization during the healing process of periocular defects treated with <i>laissez-faire</i> following tumor excision.</p><p><strong>Methods: </strong>Ten patients with periocular basal cell carcinomas underwent excision, followed by <i>laissez-faire</i> wound management. Blood perfusion was measured using laser speckle contrast imaging postoperatively.</p><p><strong>Results: </strong>Immediately after excision, perfusion increased in the wound edge and the peri-wound tissue, reaching approximately 157% of reference values (<i>p</i> < 0.01), reflecting immediate effects of surgery. At 1 week, perfusion increased further, likely driven by inflammation and angiogenesis (193%, <i>p</i> < 0.001). Perfusion gradually decreased at 6-8 weeks, aligning with active tissue remodeling, and continued to normalize at 4-5 months (123%, <i>p</i> > 0.05). By 12 months, perfusion returned to baseline levels, reflecting wound maturation (109%, <i>p</i> > 0.05). In cases with directing sutures, perfusion initially decreased to 64% at the wound edge, presumably due to tension-induced hypoperfusion, but returned to baseline after 6-8 weeks.</p><p><strong>Conclusion: </strong>This study highlights the critical role of blood perfusion in the healing of periocular defects treated with <i>laissez-faire</i>. The vascular network is preserved, enabling an immediate increase in perfusion, facilitating revascularization and wound healing. Further studies are needed to evaluate efficacy and long-term outcomes in comparison with reconstructive surgery.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-7"},"PeriodicalIF":0.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henry Bair, Leo M Hall, Tatyana Milman, Charlotte L Marous
{"title":"Delayed hematic cyst from silastic orbital implant.","authors":"Henry Bair, Leo M Hall, Tatyana Milman, Charlotte L Marous","doi":"10.1080/01676830.2025.2544034","DOIUrl":"https://doi.org/10.1080/01676830.2025.2544034","url":null,"abstract":"","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1"},"PeriodicalIF":0.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144822835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Josefina Herrera, Sophia Moshegov, Deepaysh Charanjeet, Jessica Tong, Thomas Hardy, Dinesh Selva, Jean-Louis Desousa, Simon F Taylor, Krishna Tumuluri
{"title":"Orbital abscess secondary to acute dacryocystitis.","authors":"Josefina Herrera, Sophia Moshegov, Deepaysh Charanjeet, Jessica Tong, Thomas Hardy, Dinesh Selva, Jean-Louis Desousa, Simon F Taylor, Krishna Tumuluri","doi":"10.1080/01676830.2025.2543388","DOIUrl":"https://doi.org/10.1080/01676830.2025.2543388","url":null,"abstract":"<p><strong>Purpose: </strong>To provide Australian data and a literature review on the clinical, radiological, and microbiological features and outcomes in patients with orbital abscess secondary to dacryocystitis.</p><p><strong>Methods: </strong>Multicentre retrospective review of orbital abscess secondary to acute dacryocystitis from 2019 to 2024 in Australia.</p><p><strong>Results: </strong>Eight cases were identified. The median age was 56 years (range, 26-80 years) with no gender predilection. Common presenting symptoms and signs were motility restriction (<i>n</i> = 6, 75%), proptosis (<i>n</i> = 5, 62.5%), decreased visual acuity (<i>n</i> = 4, 50%), chemosis (<i>n</i> = 3, 37.5%) and RAPD (<i>n</i> = 2, 25%). Radiologically inferomedial (<i>n</i> = 3, 37.5%) and medial (<i>n</i> = 2, 25%) orbital involvement was most commonly followed by intraconal (<i>n</i> = 2, 25%) and inferior (<i>n</i> = 1, 12.5%) orbit. Microbiological cultures revealed gram-negative bacteria (<i>n</i> = 3), gram-positive bacteria (<i>n</i> = 1), anaerobic growth (<i>n</i> = 1), polymicrobial growth (<i>n</i> = 1), MRSA (<i>n</i> = 1), and no growth (<i>n</i> = 1). Treatment included intravenous antibiotics in all cases, 4 patients underwent orbital abscess drainage combined with DCR, 1 had orbital drainage alone, 1 had endoscopic DCR alone, 1 had canthotomy with cantholysis, and 1 patient did not receive surgical treatment. One patient lost vision (light perception) with remainder having stable or improved visual acuity at follow up.</p><p><strong>Conclusion: </strong>Acute surgical management needs to be considered in majority of cases with dacryocystitis and orbital abscess. Signs of orbital involvement in acute dacryocystitis should be identified promptly to prevent irreversible visual loss.</p>","PeriodicalId":47421,"journal":{"name":"Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery","volume":" ","pages":"1-8"},"PeriodicalIF":0.8,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144822836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}