Journal of International Society of Preventive and Community Dentistry最新文献

{"title":"Cytotoxicity, Antimicrobial, Anti-inflammatory and Antioxidant Activity of Camellia Sinensis and Citrus Mediated Copper Oxide Nanoparticle-An <i>In vitro</i> Study.","authors":"Swati Singh, Arya S Prasad, Shanmugam Rajeshkumar","doi":"10.4103/jispcd.JISPCD_76_23","DOIUrl":"10.4103/jispcd.JISPCD_76_23","url":null,"abstract":"<p><strong>Aim: </strong>Several applications of copper oxide nanoparticles (CuONPs) have been documented in various fields, including healthcare, dentistry, medication delivery, tissue and cancer imaging, biolabeling, and biosensing. Therefore, this study aimed to synthesize CuONPs using the plant extracts of Camellia Sinesis (CS) and citrus limon (CL). The nanoparticles were then evaluated for their cytotoxicity, antibacterial, anti-inflammatory, and antioxidant activities.</p><p><strong>Materials and methods: </strong>CuONPs were prepared using CS and CL through the green synthesis method. The Zone of Inhibition (ZOI) test was used to assess the antibacterial activity against strains of <i>Staphylococcus aureus</i>, <i>Enterococcus faecalis</i>, <i>Streptococcus mutans</i>, and <i>Candida albicans</i>. The albumin denaturation assay was used to assess the substances' anti-inflammatory activity. The cytotoxicity was determined by conducting the brine shrimp lethality test. Additionally, the antioxidant nature was tested using the 1,1-diphenyl-2-picryl hydrazyl method.</p><p><strong>Results: </strong>CuONPs mediated by CS and CL were successfully synthesized. The nanoparticles demonstrated significant antimicrobial activity against the bacteria being studied, specifically <i>S. aureus</i>. The cytotoxic effect was observed to be the least when the concentrations were below 20 µL. A potent antioxidant effect, characterized by its maximum absorbance at 517 nm, was observed at a concentration of 50 µL. A significant anti-inflammatory effect was noted for all tested concentrations.</p><p><strong>Conclusion: </strong>The use of CS- and CL-mediated CuONPs demonstrates a favorable antimicrobial effect with reduced cytotoxicity, as well as improved anti-inflammatory and antioxidant effects at higher concentrations.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 6","pages":"450-457"},"PeriodicalIF":1.4,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized Cross-over Trial of Behavior Guidance Techniques on Children with Special Needs during Dental Treatment: The Caregivers' Perceived Mannerisms.","authors":"Norsaima Ismail, Khairil Anuar Md Isa, Siti Hajar Hamzah, Ilham Wan Mokhtar","doi":"10.4103/jispcd.JISPCD_52_23","DOIUrl":"10.4103/jispcd.JISPCD_52_23","url":null,"abstract":"<p><strong>Aim: </strong>To compare caregivers' acceptance, consent, and concern toward utilization of a combination of basic behavior guidance technique (CBBGT) and Papoose Board (PB) for their special needs children and to evaluate the impact of PB usage on the caregiver's attitude and the association between their education level, monthly household income, and previous dental experience.</p><p><strong>Materials and methods: </strong>This cross-over study incorporated 90 special needs children who were recruited to receive dental treatment with two ways of behavior guidance exposures consecutively in the order of A-B/B-A design. Exposure A is CBBGT (distraction, tell-show-do, and positive reinforcement), while Exposure B is PB. The dental procedures were either dental prophylaxis or restoration with a handpiece. Caregivers need to answer a paper-based questionnaire before and after exposure. The Wilcoxon sign rank test and logistic regression were utilized in order to establish the comparability, impacts, and association.</p><p><strong>Result: </strong>About 88 caregivers of special needs children aged between 2 and 15 years completed the sequence. Overall, 98.9% of the children presented with neurodevelopmental disorders. Twenty-seven caregivers were significantly concerned when the combination of basic BGT was applied to their children, and 14 caregivers felt the same for PB. However, the Wilcoxon sign rank test revealed insignificant caregiver scores on acceptance and consent for both methods but significantly improved attitudes towards the use of PB after observing the placement of their children.</p><p><strong>Conclusion: </strong>The studied caregiver demonstrated equivalent acceptance, consent, and concern toward the use of PB and a combination of basic BGT with improved attitudes after comprehensive explanation and real-time observation of PB usage during their children's dental treatment.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 6","pages":"500-508"},"PeriodicalIF":1.4,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Drinking Water Fluoride on Gingivitis and Caries: A Study in Peat and Non-Peat Land: A Comparative Cross-Sectional Study.","authors":"Sri Rezki, Sunardi Sunardi, Dudi Aripin, Khayan Khayan, Pawarti Pawarti, Aisya Rezki Noeriman","doi":"10.4103/jispcd.JISPCD_127_23","DOIUrl":"10.4103/jispcd.JISPCD_127_23","url":null,"abstract":"<p><strong>Aim: </strong>Humans get fluoride from food and water available in their environment. The source of clean water in peatlands comes from rainwater with a low mineral content, especially fluoride. The objective of this study was to investigate the correlation between the fluoride level in drinking water and salivary fluoride levels, as well as their potential impact on dental and oral health conditions.</p><p><strong>Materials and methods: </strong>It is a causal-comparative study with a cross-sectional approach at the Health Polytechnics of Pontianak and Yogyakarta. The population were indigenous people in peat land (Pontianak) and non-peat land (Yogyakarta). The data were pH and mineral content in drinking water, saliva, the number of <i>Streptococcus mutans</i> colonies, dental caries rates, and gingivitis.</p><p><strong>Results: </strong>Drinking water fluoride is only significantly correlated with salivary fluoride on non-peat land. If these data are combined, it can be seen that drinking water fluoride is positively correlated (<i>P <</i> 0.05; CI 95%) with pH water, fluoride water, and pH saliva. Increased levels of fluoride in drinking water were negatively correlated with gingivitis, dental caries, and <i>S. mutans</i>.</p><p><strong>Conclusion: </strong>Drinking water fluoride is negatively correlated with dental caries and gingivitis in peatland and non-peatland communities, but would be significantly associated with dental caries and gingivitis if both peatland and non-peatland data were analyzed together. This is due to the low content of fluoride in the drinking water of peatland. Therefore, it is necessary to add fluoride gel to the teeth to prevent the development of dental caries.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 6","pages":"509-515"},"PeriodicalIF":1.4,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Barriers and Expectations Towards Health Care Services Among Parents/Caretakers of People with Intellectual Disability in Kuantan, Malaysia: A Qualitative Study.","authors":"Farah Natashah Mohd, Abdul Hadi Said, Mas Suryalis Ahmad, Ain Nuha Ridzwan, Amira Izwani Muhammad, Ahmad Syahir Mat Naji","doi":"10.4103/jispcd.JISPCD_89_23","DOIUrl":"10.4103/jispcd.JISPCD_89_23","url":null,"abstract":"<p><strong>Backgrounds: </strong>People with intellectual disabilities (PWID) are often characterized by challenges in learning and difficulties in performing daily activities. These difficulties can have an impact not only on the individuals themselves but also on the people around them, especially their parents, caregivers, and healthcare workers. Therefore, establishing a positive relationship between parents or caregivers and individuals with disabilities is crucial as a key factor in promoting positive healthcare experiences and outcomes.</p><p><strong>Aim: </strong>This study aims to explore the barriers and perceptions toward healthcare services among parents or caretakers of people with intellectual disability, including the challenges and their expectations toward healthcare services.</p><p><strong>Materials and methods: </strong>This was a qualitative study using purposive sampling. Thirty participants were contacted at the initial stage and invited to participate in the study. Semi-structured in-depth interviews were done among parents and caretakers of PWID who attended Special Care Dentistry and Paediatric Dentistry clinics in Sultan Ahmad Shah Medical Centre, Kuantan, Pahang. Topic guides were generated from literature review and expert opinions, followed by pilot interviews to refine them. However, after the interviews were done for the first 13 participants, we have reached data saturation, and no new themes emerged. The interviews were recorded, verbatim transcribed, and analyzed using Braun and Clarke's guidelines for thematic analysis.</p><p><strong>Results: </strong>The satisfaction of parents or caretakers toward healthcare services for PWID and positive experiences in receiving healthcare services were noted. However, the results revealed several barrier themes in seeking healthcare services: lack of availability of parking, longer waiting time, appointment time, crowded environment, limited information on the availability of the services, and longer travel duration. Furthermore, expectation themes emerged from this study: continuous follow-up, accessibility to healthcare services, and staff attitude.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 6","pages":"477-484"},"PeriodicalIF":1.4,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Parental Rating of Child's Oral Health Associated with Caries Experience in Children? A Cross-Sectional Study.","authors":"Faisal F Hakeem, Hassan A Hammudah, Abdulmajid A Masoudi, Abdulsamad T Habeeb, Rola M Aljohani, Shahad N Almutairi","doi":"10.4103/jispcd.JISPCD_110_23","DOIUrl":"https://doi.org/10.4103/jispcd.JISPCD_110_23","url":null,"abstract":"<p><strong>Aim: </strong>The Parents' view to the oral health of their children is a significant factor that can impact oral health practices and behaviors. The aim of this research was to investigate how parental assessment of their child's oral health associates with caries experience in children receiving dental treatment at the hospital of Taibah University Dental College.</p><p><strong>Materials and methods: </strong>This cross-sectional study enrolled 127 children who underwent dental treatment at Taibah University Dental College and Hospital during 2020-2021. Dental caries experience was assessed using the dmft/DMFT index, and parental rating of oral health was obtained through a questionnaire. Three logistic regression models were used to assess the correlation between dental caries experience and parental rating of oral health while controlling for sociodemographic and behavioral factors.</p><p><strong>Results: </strong>Most parents rated the oral health of their child as good (60.4%), followed by excellent (18.8%) and very good (15.6%). The mean dmft/DMFT score was 3.47 ± 3.46, with 43.8% of children having high/very high dental caries experience. Logistic regression analysis showed that children whose parents rated their oral health as poor were more likely to have high/very high dental caries experience compared to those rated as excellent/very good/good/fair (adjusted odds ratio = 4.45, 95% confidence interval 1.23-16.07).</p><p><strong>Conclusion: </strong>This study suggests a link between parental assessment of their child's oral health and an elevated prevalence of dental caries in children. The study found that children whose parents rated their oral health as suboptimal had higher odds of having high dental caries experience. These findings emphasize the significance of parental perception of their child's oral health and suggest a necessity for customized interventions to enhance parental knowledge and practices concerning children's oral health.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 6","pages":"485-492"},"PeriodicalIF":1.1,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Xerostomia and Angular Cheilitis in Geriatric Population among Clinical Dental Students: An Institutional Cross-Sectional Study.","authors":"Fatma Y Mahdani, Galuh D Jati, Erine T Febrine, Karina W Cahyaningrum, Desiana Radithia, Satutya Wicaksono","doi":"10.4103/jispcd.JISPCD_91_23","DOIUrl":"10.4103/jispcd.JISPCD_91_23","url":null,"abstract":"<p><strong>Aim: </strong>Assessing the knowledge of clinical dental students regarding prevalent geriatric oral diseases is crucial in evaluating their clinical competency. This study focuses on analyzing dental students' knowledge of angular cheilitis (AC) and xerostomia in elderly patients.</p><p><strong>Materials and methods: </strong>In this analytical cross-sectional investigation, clinical dental students from Universitas Airlangga were involved. We employed simple random sampling to select a minimum of 76 students and gathered data, including demographic information and knowledge about AC and xerostomia, through an online questionnaire. Respondents were then categorized into three groups based on their knowledge level: poor, moderate, and good. We utilized coefficient contingency and odds ratio analysis to explore relationships and effects between demographic factors and knowledge levels.</p><p><strong>Results: </strong>The study findings indicated that a significant majority of respondents demonstrated a high level of comprehension regarding AC (58.4%). Conversely, a notable proportion of respondents exhibited limited knowledge regarding xerostomia (66.3%). Furthermore, our correlation analysis, which aimed to identify potential associations between knowledge levels and intrinsic factors such as gender, clinical interest, and proximity to geriatric individuals, did not reveal any statistically significant relationships (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>Within the population of clinical dental students, there is a commendable level of knowledge concerning AC in the geriatric demographic. However, a substantial segment of students lacks adequate understanding when it comes to xerostomia.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 6","pages":"443-449"},"PeriodicalIF":1.4,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Microtensile Bond Strength in Three Different Dentin Luting Agents: An <i>In vitro</i> Study.","authors":"Leonor Cristina Castro-Ramirez, Marysela Irene Ladera-Castañeda, Hernán Rafael Cachay-Criado, María Isabel Alvino-Vales, Carlos López-Gurreonero, Luis Adolfo Cervantes-Ganoza, César Félix Cayo-Rojas","doi":"10.4103/jispcd.jispcd_299_21","DOIUrl":"10.4103/jispcd.jispcd_299_21","url":null,"abstract":"<p><strong>Aim: </strong>Long-term clinical success on indirect restorations is largely determined by bonding efficiency of the luting agent, with adhesion to dentin being the main challenge. Therefore, aim of this study was to assess the microtensile bond strength when using flowable resin composite, preheated resin composite and dual self-adhesive resin cement as dentin luting agents.</p><p><strong>Materials and methods: </strong>Occlusal thirds of molar teeth were cut and randomly divided into 3 groups to be cemented: RelyX™U200, Filtek™ Z250 XT- preheated to 70° and Filtek Flow™ Z350XT. They were then thermocycled 5000 times between 5+/-2°C and 55+/-2°C. Subsequently, 10 microbars per group were prepared. The 30 samples were placed in saline solution for 24 hours at room temperature prior to microtensile test. This was performed with a digital universal testing machine at a crosshead speed of 0.5 mm/min. The bond strength values obtained were analyzed in Megapascals (MPa). Measures of central tendency such mean and measures of dispersion such standard deviation were used. In addition, the Kruskall Wallis non-parametric test with Bonferroni post hoc test was applied, considering a significance value of 5% (<i>P</i> < 0.05), with type I error.</p><p><strong>Results: </strong>The dentin microtensile bond strengths of preheated resin composite, flowable resin composite and dual self-adhesive cement were 6.08 ± 0.66 Mpa, 5.25 ± 2.60Mpa and 2.82 ± 1.26Mpa, respectively. In addition, the preheated resin composite exhibited significantly higher microtensile bond strength compared to the dual self-adhesive cement (<i>P</i> < 0.001). While the flowable resin composite showed no significant difference with the dual self-adhesive cement (<i>P</i> = 0.054) and the preheated resin composite (<i>P</i> = 0.329).</p><p><strong>Conclusions: </strong>The microtensile bond strength in dentin was significantly higher when using a preheated resin composite at 70°C as a luting agent compared to dual self-adhesive cement. However, the preheated resin composite showed similar microtensile bond strength compared to the flowable resin composite.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"14 1","pages":"43-51"},"PeriodicalIF":1.1,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10980309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Awareness about Oral Manifestations of Diabetes Mellitus Among Type -II Diabetes Patients in Chengalpet District, Tamil Nadu, India","authors":"S. Prabhu, Aryasri Premarajan Kolankada, Aparna S. Nair, Amritha Blessy, Juhi Julius, Anith Musolini Krishnamoorthi, Vishal Loganathan","doi":"10.56501/intjcommunitydent.v11i2.885","DOIUrl":"https://doi.org/10.56501/intjcommunitydent.v11i2.885","url":null,"abstract":"Introduction : The aim of this study is to assess the knowledge and awareness about oral manifestations of diabetes among diabetic patients in Chengalpet district.\u0000Materials and Methods : A cross- sectional study was conducted using a self-administered questionnaire consisting of different statements on knowledge and awareness of diabetic patients on the oral manifestations of diabetes mellitus (n = 153). The questionnaire included the demographic data, drug history, periodontal and dentition changes, their oral hygiene practices and their knowledge about the oral manifestations of diabetes mellitus.\u0000Results : A total of n = 153 patients were included, n = 77 (50.3%) patients were male and n = 76 (49.6%) were female. The results of this study showed that a majority of people with diabetes are unaware of the bidirectional link between diabetes and its oral manifestations and they have limited knowledge of their risks for oral health problems. Majority of the patients were not aware about the oral manifestations such as Bleeding from gums n = 114 (75.1%), Burning Sensation n = 113 (74.3%), Altered Taste Sensation n = 118 (77.6%), Oral Malodourn = 125 (82.2%), Increase in Dental caries n = 105 (69.1%), Mobility of teeth n = 108 (71.1%). The results also showed that n = 73 (48%) of the participants were aware about the dryness of mouth.\u0000Conclusion : Patients with diabetes mellitus are not well-informed or aware of the oral symptoms of the disease.","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"29 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83442772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are Adults Over 18 Years of Age with Anaemia More Likely to Develop Chronic Periodontitis Than Adults Without Anaemia? - A Systematic Review and Meta-Analysis.","authors":"Madison Roberts,&nbsp;Sudha Jimson,&nbsp;Mythily Srinivasan","doi":"10.4103/jispcd.JISPCD_37_23","DOIUrl":"10.4103/jispcd.JISPCD_37_23","url":null,"abstract":"<p><strong>Aims and objectives: </strong>Periodontitis is a chronic disease affecting the supporting tissues of the teeth and exhibits bidirectional relation with systemic diseases. This study aims to determine the association between chronic periodontitis and erythrocyte functional measures: total red blood cells (RBCs), hemoglobin (Hb) concentration, mean corpuscular volume (MCV), and mean corpuscular hemoglobin concentration (MCHC) by systematic review and meta-analysis.</p><p><strong>Materials and methods: </strong>A systematic search of the electronic databases PUBMED, OVID, Embase, Web on Science, and Google Scholar was undertaken from inception to July 2022. English language studies that evaluated the erythrocyte functional measures in periodontitis and health were selected. Other review reports, letters/opinion articles, studies without a definition of periodontitis, and the concomitant presence of systemic conditions (diabetes, kidney disease, cancer) were excluded. Two reviewers determined full-text eligibility in a blinded process. Meta-Essentials software was used to generate forest plots and to determine heterogeneity and publication bias.</p><p><strong>Results: </strong>Twenty-six studies involving 1082 patients with chronic periodontitis and 980 healthy controls were analyzed. Pooled results showed lower Hb concentration (Hedges' <i>g</i> = -1.16; 95% confidence intervals [CI], -1.7 to -0.62), RBC counts (Hedges' <i>g</i> = -0.85; 95% CI, -1.31 to -0.38) and packed cell volume (-0.56; 95% CI, -1.02 to -0.11) in patients with chronic periodontitis.</p><p><strong>Conclusion: </strong>This meta-analysis showed a decreasing trend in the hematological parameters, including hemoglobin concentration, number of erythrocytes, and hematocrit in patients with chronic periodontitis compared to healthy controls.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 1","pages":"287-298"},"PeriodicalIF":1.1,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/91/JISPCD-13-287.PMC10593371.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45492556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interactive Effect of Salivary Protein Carbonyl, Total Glutathione, pH, and Flow Rate on Root Caries Severity: A Case-Control Study.","authors":"Baydaa Ahmed Yas","doi":"10.4103/jispcd.JISPCD_186_22","DOIUrl":"10.4103/jispcd.JISPCD_186_22","url":null,"abstract":"Aims and Objectives: Oxidant and antioxidant components in saliva play an essential role in caries development. The purpose of the current study was to disclose the interactive effect of salivary protein carbonyl (PC), total glutathione (GSH), pH, and flow rate on root caries severity. Materials and Methods: The control and study groups consisted of 90 older adults of both genders classified into six groups: normal salivary flow rate with no root caries (control), normal salivary flow rate with incipient root caries, normal salivary flow rate with shallow root caries, hyposalivation with no root caries, hyposalivation with incipient root caries, and hyposalivation with shallow root caries. Each group consisted of 15 older adults. The study participants were selected from those patients who attended the teaching hospital at the College of the Dentistry/University of Baghdad and fit the study’s criteria. Unstimulated saliva was collected. Both salivary pH and flow rate were determined immediately. After that, saliva was subjected to biochemical analysis to determine PC and total GSH levels colorimetrically. Root surface caries was diagnosed clinically using the Root Caries Index. Data were statistically analyzed using descriptive statistics, two-way univariate analysis of variance, two-way multivariate analysis of variance, and Pearson’s correlation coefficient (α = 5%). Results: Salivary total glutathione revealed a significant interactive effect with salivary flow rate and root decay severity. Levels of salivary total GSH were significantly higher in subjects with shallow root caries than those with incipient root caries; no root caries levels of salivary PC were significantly high in the hyposalivation group, but no correlation with caries severity was found. High root caries severity was found to be associated with reduced salivary pH and flow rate. Conclusion: A significant interactive effect was recorded for salivary flow rate, pH, and total GSH on root caries severity except for salivary PC.","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"13 1","pages":"318-326"},"PeriodicalIF":1.1,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6b/79/JISPCD-13-318.PMC10593372.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46045774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}