{"title":"STATE OF HEMATOLOGICAL INDICATORS AND MICROELEMENT COMPOSITION OF BLOOD IN PREMATURE BABIES WITH PERINATAL POSTHYPOXIC ENCEPHALOPATHY IN THE EARLY NEONATAL PERIOD","authors":"Dilorom Akhmedova, Barno Inakova, Khusan Kadirov","doi":"10.56121/2181-2926-2023-2-6-229-232","DOIUrl":"https://doi.org/10.56121/2181-2926-2023-2-6-229-232","url":null,"abstract":"The article provides data on the state of hematological parameters and microelement composition of blood in premature infants with perinatal post hypoxic encephalopathy in the early neonatal period. It was established that the content of erythrocytes and hemoglobin in the blood during dynamic observation in premature newborns with PEP compared with their levels in infants full-term with PEP and in the control, group revealed unreliably lower values of these indicators in the 1st, 3rd, 5-7th days of life. In the group of premature infants with PEP, a moderate positive relationship was established between the zinc content in the blood serum of mothers and in the umbilical cord blood serum of their children. Direct correlations between zinc concentrations were revealed in the 1st and 2nd, and in the 2nd and 3rd studies.","PeriodicalId":471731,"journal":{"name":"Международный журнал научной педиатрии","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CLINICAL FUNCTIONAL CHARACTERISTICS OF SICK CHILDREN WITH GLOMERULONEPHRITIS WITH INCREASED THYROID FUNCTION","authors":"Arzibekov Abdikadir, Arzikulov Abduraim, Arzibekova Umida","doi":"10.56121/2181-2926-2023-2-6-244-248","DOIUrl":"https://doi.org/10.56121/2181-2926-2023-2-6-244-248","url":null,"abstract":"Abstract: To date, there have been few works on a comprehensive study of the functional state of the thyroid gland in glomerulo- and pyelonephritis in children, but there is no consensus on the nature of these relationships (12,13,14). Purpose of the work: to study the clinical and functional characteristics of sick children with glomerulonephritis with increased thyroid function. Material and methods of research: The work is based on clinical observations, examination and treatment of 22 children with glomerulonephritis with hyperfunction of the thyroid gland aged 5 to 17 years, who were hospitalized in the neurological department. Conclusions: characterizing the features of the clinical course of glomerulonephritis in children with increased activity of the thyroid system, one should first of all note the presence of 2 clinical variants of the disease: acute glomerulonephritis with nephritic syndrome, which was characterized by an acute onset with symptoms of general intoxication, early appearance of renal symptoms, and the presence of mixed polymorphic urinary syndrome , pronounced edema, a variety of extrarenal changes.","PeriodicalId":471731,"journal":{"name":"Международный журнал научной педиатрии","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yulduz Rasul-zoda, Dilnoza Melieva, Abdurayim Arzikulov
{"title":"CIRCULATION IN THE BLOOD COMPOSITION OF PREECLAMPSIA PROGNOSTIC BIOMARKERS","authors":"Yulduz Rasul-zoda, Dilnoza Melieva, Abdurayim Arzikulov","doi":"10.56121/2181-2926-2023-2-6-223-228","DOIUrl":"https://doi.org/10.56121/2181-2926-2023-2-6-223-228","url":null,"abstract":"The article, based on an analysis of modern literature, discusses the etiology and pathogenesis of the most dangerous complication of pregnancy - preeclampsia and the possibilities of predicting this pathology. The relevance of the problem associated with preeclampsia is due to its leading third position in the structure of maternal mortality, as well as serious long-term cardiometabolic disorders in women who have suffered this complication, which significantly reduce their quality of life. Based on the results of studying the pathogenesis of preeclampsia, new biomarkers (substances used as indicators of a biological state) were identified; this concept is used to characterize markers suitable for predicting a biological condition, such as preeclampsia, for early detection and prevention of this pathology.","PeriodicalId":471731,"journal":{"name":"Международный журнал научной педиатрии","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CLINICAL AND ANAMNESTIC FEATURES OF THE DYNAMICS AND TRANSFORMATION OF IRON-DEFICIENCY ANEMIA IN ADOLESCENT GIRLS","authors":"Shaira Atajanova, Abdurayim Arzikulov, Gavhar Nuritdinova","doi":"10.56121/2181-2926-2023-2-6-233-238","DOIUrl":"https://doi.org/10.56121/2181-2926-2023-2-6-233-238","url":null,"abstract":"Annotation: According to the World Health Organization, in any population, for every person suffering from IDA, there are three with iron deficiency (IAD). The risk group for the development of anemia includes children, women of reproductive age and the elderly. A special group among them are girls of pubertal age, who have a high potential for the formation of various organ dysfunctions. The purpose of this work was to study the clinical and anamnestic features of the dynamics and transformation of iron deficiency anemia in adolescent girls. Object and methods of the study: adolescent girls aged 12-14 years (n=177) of the Uzbek population, respectively, with LAD (45), mild IDA (56) and moderate (25), and the control group (51). For the study, whole blood and serum of adolescent girls with IDA were used. General clinical, instrumental, biochemical and statistical methods were used. Results: From the data of our material it follows that the clinical picture of IDA in schoolgirls was somewhat transformed and among them the syndrome of decreased immunological resistance of the body and gastrointestinal syndrome began to prevail, their frequency increased by more than 2-5 times compared to the above authors. The clinical picture of iron deficiency anemia in adolescent girls is characterized by polymorphism of symptoms and syndromes, which indicates the involvement of many organs and systems in the pathological process. It is concluded that it is necessary to update data on the clinical symptoms of ID in adolescent girls, depending on age, gender and regions of residence.","PeriodicalId":471731,"journal":{"name":"Международный журнал научной педиатрии","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COMPARATIVE AGE FEATURES OF CLINIC AND PATHOGENETIC ASPECTS OF SCHOOL DISADAPTATION","authors":"Madinabonu Abdumukhtarova, Abdurayim Arzikulov","doi":"10.56121/2181-2926-2023-5-27-29","DOIUrl":"https://doi.org/10.56121/2181-2926-2023-5-27-29","url":null,"abstract":"Intensive processes of maturation of certain biological systems of the body in conjunction with an increase in the level of socio-psychological requirements for students, increase the possibility of psihotrauvmatik personality. The clinic manifestations and the main factors of pathogenesis of school disadaptation in the comparative-age aspect (7-11 years old, n = 950) and (12-17 years old, n = 550). More significant factors of risk together with the psycho - social ones (conditions of micro social sphere of family and school) are genetic and cerebral organic. The feature of found out by children and teenagers disadaptation is its massive somatisation, which charactrised by polymorph vegetative and visceral disorders in different organs and systems (digestive, skin, respiratory, moving, heart-vessel,secretory,endocrine) and paintful manifestation. Results. Thus, clinical and population-based studies conducted amonghealthy schoolchildren, revealed a greater incidence of children and adolescents with adjustment disorders (72%), among which is dominated by Grade III - a relative maladjustment. The most significant risk factors, along with psycho-social (micro social status of the family and school environment) are genetic and cerebro-organic. A feature of the identified children and adolescents maladjustment was its massive somatic, which was characterized by polymorphic vegetative-visceral disorders in various organs and systems (digestive, skin, respiratory, locomotor, cardiovascular, excretory, endocrine) and algic manifestations.","PeriodicalId":471731,"journal":{"name":"Международный журнал научной педиатрии","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135434668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"НОВЫЙ ПОДХОД К ЛЕЧЕНИЮ РЕСПИРАТОРНЫХ ЗАБОЛЕВАНИЙ У ЧАСТО БОЛЕЮЩИХ ДЕТЕЙ","authors":"Нурали Шавази, Хиромон Сирожиддинова","doi":"10.56121/2181-2926-2023-1-33-36","DOIUrl":"https://doi.org/10.56121/2181-2926-2023-1-33-36","url":null,"abstract":"В статье приведены показатели иммуноглобулинов и стафилококкового антитоксина при совместном применении Бронхо-мунала и Нуклеинат натрия у часто болеющих детей в лечении респираторных заболеваний. Изучены показатели трех классов иммуноглобулинов (A,M,G) и стафилококкового антитоксина у 146 часто болеющих детей, от 1 года до 6 лет госпитализированных в отделении пульмонологии ГДБ №1 г. Самарканда. Из них 46 лечились традиционным методом (Т), 50 – традиционным методом с применением Бронхо-мунала (ТБ) и 50 – традиционным методом с применением Бронхо-мунала и адъюванта Нуклеината натрия (ТБН). Исследования проводились до лечения (146) и в динамике перед выпиской из стационара (146). Положительное влияние разработанного метода лечения проявлялось в исчезновении признаков интоксикации и купировании клинических симптомов за короткие сроки, повышении показателей неспецифических и специфических факторов с образованием антитоксического и антибактериального иммунитета в индуктивной и продуктивной фазе.","PeriodicalId":471731,"journal":{"name":"Международный журнал научной педиатрии","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135599975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Махмуд Алиев, Голибжон Туйчиев, Фаррух Нематжонов, Гофуржон Туйчиев
{"title":"УЛУЧШЕНИЕ РЕЗУЛЬТАТОВ БИЛИОДИГЕСТИВНОГО АНАСТОМОЗА ПРИ КИСТЕ ХОЛЕДОХА У ДЕТЕЙ","authors":"Махмуд Алиев, Голибжон Туйчиев, Фаррух Нематжонов, Гофуржон Туйчиев","doi":"10.56121/2181-2926-2023-2-1-04-08","DOIUrl":"https://doi.org/10.56121/2181-2926-2023-2-1-04-08","url":null,"abstract":"Лечение кистозной трансформации общего желчного протока (КТОЖП) хирургическое, «золотым стандартом» на сегодняшний день считается гепатикоеюноанастомоз на отключенной петле по Ру, однако пассаж желчи после данного оперативного вмешательства вызывает ряд осложнений, в частности дисфункцию кишечника. Это является основным толчком для разработки новых методов хирургического лечения, позволяющих сохранить пассаж желчи через 12 перстной кишки. Цель исследования: Улучшение результатов лечения кистозных трансформации желчевыводящих путей у детей. Материал и методы исследования: Анализ проведен у 48 детей в возрасте 3-14 лет больных кистозных трансформации желчевыводящих путей, находившихся на стационарном лечении в клинике детской хирургии ТашПМИ и РСНПМЦ Педиатрии и АндГосМИ за период с 2012 по 2020 гг. Диагностические методы включали ряд общепринятых клинических и биохимических исследований крови, позволяющих судить о степени угнетения функций печени. Также проводился ряд специальных методов исследования: ультразвуковое исследование печени, желчевыводящих путей и селезенки, мультиспиральная компьютерная томография, магнитно-резонансная томография без контрастной холангиографией, морфологическое исследование печеночной паренхимы и кистозно измененного холедоха, желчного пузыря, непрямая эластометрия печени, оценивалась коагуляционная активность крови. Наиболее часто применяли операцию гепатикоеюноанастомоз на отключенной петле по Ру с созданием антирефлюксного механизма. Результаты и вывод. По данным исследования можно сделать вывод, что оперативное лечение кист холедоха должно проводится по установлении диагноза, при этом операцией выбора является операции гепатикоеюностомии на отключенной петле по Ру и гепатикоеюнодуоденоанастомоз по Raffensperger. Применение новых технологий обеспечивает поступление желчи непосредственно в двенадцатиперстную кишку, что, способствует сбалансированному пищеварению.","PeriodicalId":471731,"journal":{"name":"Международный журнал научной педиатрии","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135600325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}