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Management and Outcomes of Metastatic Disease to Intra-articular Synovium, Literature Review. 关节内滑膜转移性疾病的管理和疗效,文献综述。
IF 1.7
JBJS Reviews Pub Date : 2024-11-08 eCollection Date: 2024-11-01 DOI: 10.2106/JBJS.RVW.24.00127
Al Yaqadhan Al Kindi, Yayha Al Kindi, Moosa Al Harasi, Al Khalil Al Kindi, Mohammed Al Yahyai, Majid Al Oufi, Humaid Al Farii
{"title":"Management and Outcomes of Metastatic Disease to Intra-articular Synovium, Literature Review.","authors":"Al Yaqadhan Al Kindi, Yayha Al Kindi, Moosa Al Harasi, Al Khalil Al Kindi, Mohammed Al Yahyai, Majid Al Oufi, Humaid Al Farii","doi":"10.2106/JBJS.RVW.24.00127","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00127","url":null,"abstract":"<p><strong>Background: </strong>Intra-articular metastatic disease is a rare and unique manifestation of cancer metastasis, often originating from primary tumors such as lung adenocarcinoma, colorectal carcinoma, and malignant melanoma. The clinical symptoms frequently mimic chronic inflammatory arthritis, complicating diagnosis and treatment. This study aims to provide a comprehensive review of the incidence, clinical presentation, management strategies, and outcomes for patients with primary diagnosed cancers that metastasize to intra-articular locations, underscoring the specialized nature of this field.</p><p><strong>Methods: </strong>We conducted a systematic search of PubMed, Medline, and Embase databases in July 2024, yielding 239 articles on intra-articular metastasis in cancer patients. Twenty-one studies met the inclusion criteria after screening. Five reviewers abstracted and analyzed data on patient demographics, metastatic details, diagnostic evidence, treatment modalities, and outcomes.</p><p><strong>Results: </strong>The search yielded 239 articles, from which 21 studies met the inclusion criteria. The patient cohort is 24 cases with a mean age of 58.8 years. Of the 24 patients included, 18 (75%) were males and 6 (25%) were females. Colorectal carcinoma was the most frequent primary tumor (33.3%), followed by lung cancer (25%). The knees were predominantly affected by the metastases. Diagnostic modalities varied; magnetic resonance imaging, arthrocentesis, and biopsy were the most commonly used procedures. Treatment approaches were again varied and included chemotherapy, radiation therapy, and surgery in some instances.</p><p><strong>Conclusion: </strong>Intra-articular metastases, though rare, present significant diagnostic and therapeutic challenges. The clinical manifestations often mimic inflammatory arthritis, complicating timely diagnosis. As underscored by this study, effective management requires a multidisciplinary approach tailored to the patient's primary cancer type and overall health status. This highlights the complexity of the disease and the need for collaborative care. Future research should focus on increasing awareness and early detection to improve patient outcomes.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
No Difference in Outcomes, Complications, or Revision Rate for Obese vs. Nonobese Patients Following Hip Resurfacing Arthroplasty: A Systematic Review and Meta-Analysis. 髋关节置换术后肥胖与非肥胖患者的疗效、并发症或复发率无差异:系统回顾与元分析》。
IF 1.7
JBJS Reviews Pub Date : 2024-11-08 eCollection Date: 2024-11-01 DOI: 10.2106/JBJS.RVW.24.00133
Jean Shanaa, Shaheryar Asad, Guneet S Bindra, Robert Augustynski, Scott Marwin
{"title":"No Difference in Outcomes, Complications, or Revision Rate for Obese vs. Nonobese Patients Following Hip Resurfacing Arthroplasty: A Systematic Review and Meta-Analysis.","authors":"Jean Shanaa, Shaheryar Asad, Guneet S Bindra, Robert Augustynski, Scott Marwin","doi":"10.2106/JBJS.RVW.24.00133","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00133","url":null,"abstract":"<p><strong>Background: </strong>Hip resurfacing arthroplasty (HRA) offers numerous benefits over total hip replacements such as increased preservation of natural bone, improved range of motion, and lower dislocation risks. However, patient selection is crucial, with factors such as bone quality, activity level, and body mass index (BMI) playing significant roles. Obesity in particular poses challenges, potentially increasing mechanical load on the joint, complicating surgical techniques, and affecting both immediate and long-term outcomes. The aim of this systematic review was to evaluate outcomes of HRA in obese vs. nonobese patients to determine if obesity should be considered a contraindication to HRA or if similar treatment approaches can be applied.</p><p><strong>Methods: </strong>A literature search was conducted using PubMed, Embase, and Scopus databases with specific search terms related to HRA and obesity. Articles were screened by title and abstract, followed by full-text review. Data extraction focused on demographic and study variables such as sex, age, BMI, complication and revision rates, and patient-reported outcomes. A meta-analysis was performed using a random-effects model to compare University of California Los Angeles (UCLA) scores, Harris hip scores, complication rates, and revision rates between obese and nonobese patients, with significance set at p < 0.05.</p><p><strong>Results: </strong>From an initial pool of 39 articles, 4 met inclusion criteria, encompassing 1,385 patients. Analysis revealed a pooled mean age of 50.92 years and a complication rate of 9.83% in obese vs. 4.7% in nonobese patients. Revision rates were 1.15% for obese and 3.70% for nonobese patients. The difference in postoperative UCLA scores, complication rates, and revision rates were deemed not statistically significant.</p><p><strong>Conclusion: </strong>The comparability in patient-reported outcomes, complication rates, and revision rates between obese and nonobese cohorts suggests that although heightened vigilance and tailored approaches may be warranted in obese patients, obesity alone should not preclude patients from undergoing HRA. These findings advocate for a more nuanced approach to patient selection, emphasizing individualized assessment over generalized BMI cutoffs. Future HRA research should focus on long-term follow-up and larger cohort studies to further validate these results.</p><p><strong>Level of evidence: </strong>Level III, systematic review of Level II and III studies. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concomitant Arthroscopic Superior Labral and Rotator Cuff Repair: A Systematic Review. 关节镜下同时进行上唇和肩袖修复术:系统回顾
IF 1.7
JBJS Reviews Pub Date : 2024-11-05 eCollection Date: 2024-11-01 DOI: 10.2106/JBJS.RVW.24.00138
Dana G Rowe, Eoghan T Hurley, Mikhail A Bethell, Tom R Doyle, Alex M Meyer, Samuel G Lorentz, Christopher S Klifto, Brian C Lau, Jonathan F Dickens
{"title":"Concomitant Arthroscopic Superior Labral and Rotator Cuff Repair: A Systematic Review.","authors":"Dana G Rowe, Eoghan T Hurley, Mikhail A Bethell, Tom R Doyle, Alex M Meyer, Samuel G Lorentz, Christopher S Klifto, Brian C Lau, Jonathan F Dickens","doi":"10.2106/JBJS.RVW.24.00138","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00138","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to systematically review the literature on concomitant repair of superior labral and rotator cuff tears, in light of the paucity of published clinical evidence.</p><p><strong>Methods: </strong>A Preferred Reporting Items for Systematic Reviews and Meta-Analyses compliant search of PubMed, Embase, and Cochrane Library databases was performed for clinical studies of patients undergoing combined repairs of the rotator cuff and superior labrum.</p><p><strong>Results: </strong>Ten studies comprising 241 shoulders were included, with a mean age of 52.6 years and mean follow-up of 29.0 months; 67.9% were male patients. Functional outcomes included the mean postoperative American Shoulder and Elbow Surgeons Standardized Shoulder Score of 88.6, University of California at Los Angeles Shoulder Score of 30.6, constant score of 90.4, Simple Shoulder Test score of 8.6, and visual analog scale score of 1.1. Range of motion outcomes demonstrated mean postoperative forward flexion of 159°, external rotation of 68°, and internal rotation of 17°. The overall return-to-play rate was 76.8%, with 67.9% returning to preinjury level. The overall complication rate was 4.1% with an 18.9% rate of rotator cuff retear and 2.4% reoperation rate.</p><p><strong>Conclusion: </strong>Arthroscopic concomitant repair of superior labral and rotator cuff tears results in good functional outcomes and range of motion, along with a low reoperation rate. Among athletes, there are moderate rates of return but lower rates of return to the same level of play.</p><p><strong>Level of evidence: </strong>Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Concepts in Orthobiologics for Achilles Tendon Injuries: A Critical Analysis Review. 跟腱损伤矫形生物学的当前概念:批判性分析综述。
IF 1.7
JBJS Reviews Pub Date : 2024-11-05 eCollection Date: 2024-11-01 DOI: 10.2106/JBJS.RVW.24.00144
Varun Gopinatth, Tanya Boghosian, Julia M Perugini, Matthew V Smith, Derrick M Knapik
{"title":"Current Concepts in Orthobiologics for Achilles Tendon Injuries: A Critical Analysis Review.","authors":"Varun Gopinatth, Tanya Boghosian, Julia M Perugini, Matthew V Smith, Derrick M Knapik","doi":"10.2106/JBJS.RVW.24.00144","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00144","url":null,"abstract":"<p><p>» Platelet-rich plasma and hyaluronic acid are low-risk and potentially high-reward treatments for Achilles tendinopathy, although clinical studies have yielded mixed results with questionable methodological quality» Case series and reports have reported that bone marrow aspirate, stem cells, and amniotic membrane products can improve functional outcomes, alleviate pain, and facilitate return to sport and activities, but high-level evidence studies are lacking» Exosomes are a promising novel biologic with laboratory studies showing improved collagen organization and cell proliferation, greater tendon mechanical properties, and prevention of extracellular matrix breakdown.» Standardization of protocols with clear reporting is necessary for future studies evaluating orthobiologic therapies for Achilles tendon injuries.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Implant Placement Accuracy Between Manual, Robot-Assisted, Computer-Navigated, Augmented Reality Navigated, Patient-Specific Instrumentation, and Accelerometer Navigated Total Hip Arthroplasty: A Systematic Review and Network Meta-Analysis. 人工、机器人辅助、计算机导航、增强现实导航、患者专用仪器和加速计导航全髋关节置换术的植入物放置准确性比较:系统回顾与网络元分析》。
IF 1.7
JBJS Reviews Pub Date : 2024-11-05 eCollection Date: 2024-11-01 DOI: 10.2106/JBJS.RVW.24.00120
Takanori Miura, Norio Yamamoto, Akihiro Shiroshita, Takahiro Tsuge, Akihiro Saitsu, Junya Yoshitani, Shuri Nakao, Ken Takami
{"title":"Comparison of Implant Placement Accuracy Between Manual, Robot-Assisted, Computer-Navigated, Augmented Reality Navigated, Patient-Specific Instrumentation, and Accelerometer Navigated Total Hip Arthroplasty: A Systematic Review and Network Meta-Analysis.","authors":"Takanori Miura, Norio Yamamoto, Akihiro Shiroshita, Takahiro Tsuge, Akihiro Saitsu, Junya Yoshitani, Shuri Nakao, Ken Takami","doi":"10.2106/JBJS.RVW.24.00120","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00120","url":null,"abstract":"<p><strong>Background: </strong>Malpositioning of the acetabular cup during total hip arthroplasty (THA) can lead to complications. Robotic surgery and navigation techniques aim to address this issue, but there is limited evidence regarding which method can achieve better clinical outcomes. Therefore, this network meta-analysis (NMA) aimed to compare the efficacy of various navigation methods.</p><p><strong>Methods: </strong>This NMA of prospective randomized controlled trials compared robot-assisted systems (RAS), computer-assisted navigation systems (CAS), augmented reality-based portable navigation (AR), patient-specific instrumentation (PSI), portable accelerometer-based navigation (PN), and conventional methods (C) for THA procedures. We searched MEDLINE, EMBASE, Cochrane, Central Register of Controlled Trials, International Clinical Trials Platform Search Portal, and ClinicalTrials.gov. databases. The primary outcomes included revision surgery and postoperative clinical scores, and the secondary outcomes encompassed cup placement accuracy, acetabular cup placement outliers from the Lewinnek safe zone, surgical time, and complications. We used a Bayesian random-effects NMA, and confidence of evidence was assessed using confidence in NMA.</p><p><strong>Results: </strong>We identified 45 studies including 2,122 patients. We did not find large differences in revision surgery, clinical outcome scores, cup inclination, or anteversion angle accuracy among the modalities. AR, CAS, and PSI exhibited a lower risk of outliers from safe zones than C. In addition, RAS and CAS had a longer surgical time than C.</p><p><strong>Conclusions: </strong>Robotic and navigation tools did not reduce the revision risk or enhance clinical outcomes. AR, CAS, PSI, and PN may decrease the risk of cup placement outliers in safe zones. However, the cup placement accuracy was equivalent, and the surgical time may be longer in RAS and CAS than in C.</p><p><strong>Level of evidence: </strong>Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Update on Spinal Cord Injury and Current Management. 脊髓损伤和当前管理的最新进展。
IF 1.7
JBJS Reviews Pub Date : 2024-10-24 eCollection Date: 2024-10-01 DOI: 10.2106/JBJS.RVW.24.00124
Austin H Carroll, Edward Fakhre, Alejandro Quinonez, Oliver Tannous, Addisu Mesfin
{"title":"An Update on Spinal Cord Injury and Current Management.","authors":"Austin H Carroll, Edward Fakhre, Alejandro Quinonez, Oliver Tannous, Addisu Mesfin","doi":"10.2106/JBJS.RVW.24.00124","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00124","url":null,"abstract":"<p><p>» Spinal cord injury is associated with increased lifelong cost and decreased life expectancy.» Current treatment guidelines have been limited to studies of small effect sizes and limited availability of randomized control trials.» Recovery is best correlated with the initial American Spinal Injury Association impairment scale grade with A and B less likely to recover regarding ambulation as compared with C and D grades.» Surgical intervention within less than 24 hours, especially in the cervical spine, has been associated with some motor improvement.» The use of mean arterial pressure goals and steroids to maintain perfusion and decrease secondary injury requires further study to elucidate clearer evidence-based results.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Seasonality of Childhood Bone and Joint Infection with Focus on Kingella kingae: A Systematic Review. 儿童骨与关节感染的季节性,重点是 Kingella kingae:系统回顾
IF 1.7
JBJS Reviews Pub Date : 2024-10-24 eCollection Date: 2024-10-01 DOI: 10.2106/JBJS.RVW.24.00149
Sarah Hunter, Haemish Crawford
{"title":"The Seasonality of Childhood Bone and Joint Infection with Focus on Kingella kingae: A Systematic Review.","authors":"Sarah Hunter, Haemish Crawford","doi":"10.2106/JBJS.RVW.24.00149","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00149","url":null,"abstract":"<p><strong>Background: </strong>Seasonal trends in hospitalization for childhood bone and joint infection (BJI) are reported inconsistently. True seasonal variation would suggest an element of disease risk from environmental factors. This review evaluates all reported seasonal variations in childhood BJI, with additional analysis of seasonal trends for diseases secondary to Kingella kingae.</p><p><strong>Methods: </strong>A systematic review of the literature was undertaken from January 1, 1980, to August 1, 2024. Data were extracted on the hospitalization rate by season and/or month. Pathogen-specific studies for BJI secondary to K. kingae were examined separately.</p><p><strong>Results: </strong>Twenty studies met inclusion criteria encompassing 35,279 cases of childhood BJI. Most studies reported seasonal variation (n = 15, 75%). Eight studies specifically considered disease secondary to K. kingae, and all reported more frequent hospitalization in autumn and/or winter. This is in keeping with the role of respiratory pathogens and seasonal viruses in disease etiology for K. kingae BJI. Findings from other studies on the seasonality of childhood BJI were inconsistent. There were reported seasonal peaks in autumn/winter (4 studies), summer/spring (5 studies), or no variation (5 studies). Where microbiologic data were available, Staphylococcus aureus was the primary pathogen. The quality assessment demonstrated confounding and heterogeneous inclusion criteria affecting the seasonal analysis.</p><p><strong>Conclusion: </strong>For childhood BJI caused by K. kingae, there appears to be a higher risk of hospitalization in autumn and/or winter months. This may relate to the seasonal circulation of respiratory viruses. There is currently insufficient evidence to support other forms of seasonal variation. Reported findings are likely affected by regional disease and pathogen characteristics.</p><p><strong>Level of evidence: </strong>Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Efficacy and Safety of Intramedullary Lengthening Nails vs. Alternative Techniques for Femoral Limb Lengthening: A Systematic Review and Meta-Analysis. 髓内加长钉与其他股骨肢体加长技术的疗效和安全性比较:系统回顾与元分析》。
IF 1.7
JBJS Reviews Pub Date : 2024-10-22 eCollection Date: 2024-10-01 DOI: 10.2106/JBJS.RVW.24.00113
Amirali Azimi, John E Herzenberg, Shayan Roshdi Dizaji, Philip K McClure, Fatemeh-Sadat Tabatabaei, Amir Farbod Azimi
{"title":"Comparative Efficacy and Safety of Intramedullary Lengthening Nails vs. Alternative Techniques for Femoral Limb Lengthening: A Systematic Review and Meta-Analysis.","authors":"Amirali Azimi, John E Herzenberg, Shayan Roshdi Dizaji, Philip K McClure, Fatemeh-Sadat Tabatabaei, Amir Farbod Azimi","doi":"10.2106/JBJS.RVW.24.00113","DOIUrl":"10.2106/JBJS.RVW.24.00113","url":null,"abstract":"<p><strong>Background: </strong>Limb lengthening procedures are performed for various indications, including limb length discrepancies (LLDs) and short stature. This systematic review and meta-analysis compares the efficacy and safety of the newer motorized intramedullary lengthening nails (MILNs) with the traditional alternative techniques (ATs) for femoral limb lengthening.</p><p><strong>Methods: </strong>We conducted a comprehensive literature search in the Medline, Embase, Cochrane, Web of Science, and Scopus databases, inclusive of all dates through July 1, 2023, and without language restrictions. Factors mediating outcomes included problems, obstacles, complications, total adverse events, healing/consolidation index, time to full weight-bearing, lengthening accuracy, percentage of lengthening goal achieved, and duration of hospital stay. Effect sizes were quantified using STATA 17.0. Statistical algorithms employed were random effects model standardized mean differences (SMDs) for continuous outcomes and log risk ratios (RRs) for dichotomous outcomes, both with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Our meta-analysis included 10 studies comparing MILN with AT: 180 femurs in the MILN group and 160 femurs in the AT group. This was exclusively comprised of retrospective cohort studies. When compared with AT, limb lengthening procedures utilizing MILNs had significantly lower problems (log RR, -1.35; 95% CI, -1.93 to -0.77; p < 0.001), complications (log RR, -0.56; 95% CI, -0.90 to -0.22; p = 0.001), and total adverse events (log RR, -0.69; 95% CI, -1.17 to -0.21; p = 0.005), as well as a superior bone healing index (SMD, -0.80; 95% CI, -1.32 to -0.28; p = 0.003). However, no significant differences were found in obstacles, percentage of lengthening goal achieved, lengthening accuracy, time to full weight-bearing, and duration of hospital stay.</p><p><strong>Conclusion: </strong>Limb lengthening with MILNs vs. AT may offer more favorable patient outcomes, lowering risk for problems, complications, and total adverse events, while optimizing the bone healing/consolidation index. However, the limitation of nonrandomized retrospective studies and high heterogeneity should be acknowledged.</p><p><strong>Level of evidence: </strong>Level II (meta-analysis of cohort studies). See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic Functions of the Infrapatellar Fat Pad: Implications for Knee Health and Pathology. 髌下脂肪垫的代谢功能:对膝关节健康和病理学的影响
IF 1.7
JBJS Reviews Pub Date : 2024-10-03 eCollection Date: 2024-10-01 DOI: 10.2106/JBJS.RVW.24.00110
Lee S Chou, James Zhang, Toufic R Jildeh
{"title":"Metabolic Functions of the Infrapatellar Fat Pad: Implications for Knee Health and Pathology.","authors":"Lee S Chou, James Zhang, Toufic R Jildeh","doi":"10.2106/JBJS.RVW.24.00110","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00110","url":null,"abstract":"<p><p>» Despite being historically viewed as a vestigial structure, the infrapatellar fat pad (IPFP) is now recognized as a metabolically active structure, influencing knee health through cytokine production and metabolic pathways.» With distinct anatomical regions, the IPFP contains diverse cell types including adipocytes, fibroblasts, and immune cells, influencing its functional roles, pathology, and contributions to knee disorders.» The IPFP acts as an endocrine organ by releasing adipokines such as adiponectin, leptin, and tumor necrosis factor α, regulating energy balance, immune responses, and tissue remodelling, with implications for knee joint health.» The IPFP's metabolic interactions with neighboring tissues influence joint health, clinical conditions such as knee pain, osteoarthritis, postoperative complications, and ganglion cysts, highlighting its therapeutic potential and clinical relevance.» Understanding the multifaceted metabolic role of the IPFP opens avenues for collaborative approaches that integrate orthopaedics, endocrinology, and immunology to develop innovative therapeutic strategies targeting the intricate connections between adipokines, joint health, and immune responses.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generative Artificial Intelligence and Prompt Engineering: A Primer for Orthopaedic Surgeons. 生成式人工智能和及时工程:骨科医生入门》。
IF 1.7
JBJS Reviews Pub Date : 2024-10-03 eCollection Date: 2024-10-01 DOI: 10.2106/JBJS.RVW.24.00122
Amber N Carroll, Lewis A Storms, Chaitu Malempati, Ridah V Shanavas, Sameer Badarudeen
{"title":"Generative Artificial Intelligence and Prompt Engineering: A Primer for Orthopaedic Surgeons.","authors":"Amber N Carroll, Lewis A Storms, Chaitu Malempati, Ridah V Shanavas, Sameer Badarudeen","doi":"10.2106/JBJS.RVW.24.00122","DOIUrl":"https://doi.org/10.2106/JBJS.RVW.24.00122","url":null,"abstract":"<p><p>» Generative artificial intelligence (AI), a rapidly evolving field, has the potential to revolutionize orthopedic care by enhancing diagnostic accuracy, treatment planning, and patient management through data-driven insights and personalized strategies.» Unlike traditional AI, generative AI has the potential to generate relevant information for orthopaedic surgeons when instructed through prompts, automating tasks such as literature reviews, streamlining workflows, predicting health outcomes, and improving patient interactions.» Prompt engineering is essential for crafting effective prompts for large language models (LLMs), ensuring accurate and reliable AI-generated outputs, and promoting ethical decision-making in clinical settings.» Orthopaedic surgeons can choose between various prompt types-including open-ended, focused, and choice-based prompts-to tailor AI responses for specific clinical tasks to enhance the precision and utility of generated information.» Understanding the limitations of LLMs, such as token limits, context windows, and hallucinations, is crucial for orthopaedic surgeons to effectively use generative AI while addressing ethical concerns related to bias, privacy, and accountability.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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