Alia Fazaa, Mariem Rachdi, Leila Ben Salem, Meriam El Ghardallou, Saoussen Miladi, Hiba Boussaa, Yasmine Makhlouf, Kaouther Ben Abdelghani, Ahmed Laatar
{"title":"Functional Capacity and Quality of Life in Elderly Patients With Knee Osteoarthritis.","authors":"Alia Fazaa, Mariem Rachdi, Leila Ben Salem, Meriam El Ghardallou, Saoussen Miladi, Hiba Boussaa, Yasmine Makhlouf, Kaouther Ben Abdelghani, Ahmed Laatar","doi":"10.1002/msc.70027","DOIUrl":"https://doi.org/10.1002/msc.70027","url":null,"abstract":"<p><strong>Background: </strong>Knee Osteoarthritis (KOA) can cause considerable impairment of functional capacity and quality of life (QoL), especially in elderly individuals.</p><p><strong>Objectives: </strong>To evaluate the impact of KOA on the functional capacity and QoL of elderly patients and to identify the factors associated with their impairment.</p><p><strong>Methods: </strong>This was a cross-sectional study including patients aged 65 years or more with primary KOA. Functional capacity was assessed using the WOMAC index and QoL using the WHOQOL-OLD instrument. The p significance level was set at 0.05.</p><p><strong>Results: </strong>Fifty patients were included, 3 men and 47 women, with a mean age of 71.9 ± 6.3 years. The mean WOMAC total score was 49.2 ± 21.7, WOMAC pain 12 ± 5.2, WOMAC function 33.4 ± 15.2 and WOMAC stiffness 4 ± 2.6. Factors associated with better functional capacity were the use of analgesics, functional rehabilitation and physical activity. The mean WOQOL-OLD total score was 84.2 ± 13.4. The autonomy and intimacy dimensions had the highest scores (92.1 ± 13.8 and 91.3 ± 16.5 respectively). The death and dying dimension had the lowest score (69.9 ± 37.1). Factors associated with a poor QoL were diabetes, unilateral involvement, duration of KOA, absence of analgesic treatment and the absence of physical activity. Functional limitation was significantly associated with poorer QoL.</p><p><strong>Conclusion: </strong>In our study, KOA was found to be associated with impaired functional capacity and QoL among elderly patients. Comorbidities, inadequate use of analgesics and lack of physical activity seem to be determining factors contributing to this impairment.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70027"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uma Balachandran, Hayley E Raymond, Nicholas L Pitaro, Michael M Herrera, Brocha Z Stern, Darwin D Chen, Brett L Hayden, Jashvant Poeran, Calin S Moucha
{"title":"Associations Between Patient-Reported Sleep Disturbance, Joint-Specific Health, and Global Health Before and After Total Hip or Knee Arthroplasty.","authors":"Uma Balachandran, Hayley E Raymond, Nicholas L Pitaro, Michael M Herrera, Brocha Z Stern, Darwin D Chen, Brett L Hayden, Jashvant Poeran, Calin S Moucha","doi":"10.1002/msc.70029","DOIUrl":"https://doi.org/10.1002/msc.70029","url":null,"abstract":"","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70029"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Taís de Espíndula Brehm, Anne Sofia Pang Bilby, Karla Zimmer Guizzo, Alexandre Márcio Marcolino, Heloyse Uliam Kuriki, Rafael Inácio Barbosa
{"title":"Effects of Transcutaneous Electrical Nerve Stimulation (TENS) During Functional Activities or Exercise: A Systematic Review.","authors":"Taís de Espíndula Brehm, Anne Sofia Pang Bilby, Karla Zimmer Guizzo, Alexandre Márcio Marcolino, Heloyse Uliam Kuriki, Rafael Inácio Barbosa","doi":"10.1002/msc.70020","DOIUrl":"10.1002/msc.70020","url":null,"abstract":"<p><strong>Background: </strong>TENS is a non-pharmacological adjunctive treatment commonly recommended for analgesic purposes, with widespread use and acceptance in clinical practice; however, its effects simultaneously with exercise are controversial, and there are gaps regarding its effectiveness and applicability, especially regarding the parameters and protocols used to treat pain. In view of this, the aim of this study was to systematically review the effects of TENS applied simultaneously with functional activities or exercises in the treatment of individuals with pain.</p><p><strong>Method: </strong>A bibliographic search was performed in electronic databases, including EMBASE, PubMED, Scopus, Web of Science, PEDro, SPORTDiscus, and the grey literature. The search yielded a total of 634 articles, of which only six met the inclusion criteria and were analysed individually. Of the selected studies, four evaluated the simultaneous use of TENS in patients with chronic pain, one in patients with fatigue-induced injury, and one in healthy subjects.</p><p><strong>Results: </strong>The articles selected for synthesis of the review were assessed using the RoB 2.0 risk of bias tool, which found that three of the included studies had a low risk of bias, while two studies were analysed as high risk and only one with some concern. It is concluded that the use of TENS in conjunction with functional activities and exercises may benefit people with pain.</p><p><strong>Conclusion: </strong>The studies showed that the use of TENS with high frequency and intensity at the sensory threshold and applied simultaneously with exercise produced more significant analgesic effects, but new clinical trials with robust methodological designs should be carried out.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70020"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zi Qiang Glen Liau, Jonathan Zhi Kai Toh, Lakshmanan Sathappan, Yau Hong Ng
{"title":"Predictive Factors of Short Inpatient Stay Following Total Knee Replacement.","authors":"Zi Qiang Glen Liau, Jonathan Zhi Kai Toh, Lakshmanan Sathappan, Yau Hong Ng","doi":"10.1002/msc.70022","DOIUrl":"https://doi.org/10.1002/msc.70022","url":null,"abstract":"<p><strong>Introduction: </strong>Enhanced Recovery after Surgery (ERAS) protocols adopt a multidisciplinary approach in perioperative care to reduce Length of Stay (LOS). This study aims to identify predictive factors resulting in short-stay following TKR with an ERAS programme.</p><p><strong>Methods: </strong>Retrospective analysis was performed on a consecutive series of patients who underwent unilateral TKR by a single surgeon in a tertiary institution between August 2019 and December 2021. Patient demographics, comorbidities and length of stay were collected using Electronic Medical Records. Short-stay was defined as LOS within 1 day or less, while standard-stay was defined as LOS exceeding 2 days or more. Statistical analysis was performed using R version 4.3.1. Logistic regression was performed for multivariate analysis.</p><p><strong>Results: </strong>Ninety-nine patients were included in the study, comprising 45 short-stay patients and 54 standard-stay patients. Short-stay patients were significantly younger (mean 66.1, 95% CI [64.5, 67.7], p = 0.0212) than standard-stay patients (mean 69.2, 95% CI [67.1, 71.2]). There was a significantly lower mean BMI among short-stay patients (26.98, 95% CI [25.52, 28.45], p = 0.021) than among standard-stay patients (29.31, 95% CI [27.96, 30.66]). A significantly higher proportion of short-stay patients (84.4%, 95% CI [73.4, 95.5], p = 0.00132) were premorbid community ambulant without aids than standard-stay patients (51.9%, 95% CI [38.1, 65.6]). There was no significant difference in sex, race, smoking, American Society of Anaesthesiologists score and Charlson Comorbidity Index (p > 0.05). Multivariate logistic regression revealed the following significant factors: Age < 75 (p = 0.0293), BMI < 25 (p = 0.00688), and premorbid community ambulant without aids (p = 0.0402).</p><p><strong>Conclusions: </strong>In conclusion, predictive factors for short-stay after TKR include age < 75, BMI < 25 and being premorbid community ambulant without aids.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70022"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marc A Pique Batalla, Ann Van de Winckel, Nicola E Walsh, Jennifer S Lewis
{"title":"Rehabilitation Interventions for Adults With Complex Regional Pain Syndrome: A Scoping Review Protocol.","authors":"Marc A Pique Batalla, Ann Van de Winckel, Nicola E Walsh, Jennifer S Lewis","doi":"10.1002/msc.1956","DOIUrl":"10.1002/msc.1956","url":null,"abstract":"<p><strong>Objectives: </strong>This scoping review will explore the literature related to rehabilitation interventions for the treatment of adults living with complex regional pain syndrome (CRPS), describe the domains and outcome measures used to assess their effectiveness, and examine the neurophysiological bases of these interventions.</p><p><strong>Introduction: </strong>The unremitting symptoms of CRPS, a chronic pain condition, are associated with long-term disability, poor psychological health, decreased emotional and social well-being, and reduced quality of life. Effective treatment for persistent symptoms is notoriously difficult. Therapeutic approaches such as graded motor imagery or pain exposure therapy are recommended for CRPS but show mixed results, insufficient effectiveness, variability in outcome measures, and unclear neurophysiological bases.</p><p><strong>Inclusion criteria: </strong>This review will consider studies that include any form of non-invasive rehabilitation intervention delivered by a healthcare professional in any setting for adults with a CRPS diagnosis. Quantitative, qualitative and observational studies, text and opinion papers will be considered.</p><p><strong>Methods: </strong>The Joanna Briggs Institute (JBI) methodology will be used to conduct this scoping review. MEDLINE, Embase, Scopus, APA PsycINFO, CINAHL, Cochrane, OpenGrey Google and ProQuest Dissertations and Theses Global (ProQuest) will be searched for studies in English published between 2007 and 2024. Two independent reviewers will screen the titles, abstracts, and full texts of the selected studies. Data collection will be performed using a tool developed by the researchers based on the standardised JBI tool. Data will be presented in a comprehensive narrative summary.</p><p><strong>Trail registration: </strong>https://doi.org/10.17605/OSF.IO/P967T.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e1956"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Patients With Painful Hip Osteoarthritis, Is It More Beneficial to Offer Them an Ultrasound-Guided or a Fluoroscopic-Guided Intra-Articular Corticosteroid Injection to Relieve Their Symptoms? A Systematic Review and Network Meta-Analysis.","authors":"Peter Alan Brookes, Siobhan Stynes","doi":"10.1002/msc.70005","DOIUrl":"10.1002/msc.70005","url":null,"abstract":"<p><strong>Purpose: </strong>Hip osteoarthritis (OA) is a common disabling musculoskeletal condition. Clinical guidelines recommend intra-articular corticosteroid injections (IACSI) as a pharmacological adjunct to help manage pain. IACSI are typically image-guided either by ultrasound guidance (USG) or fluoroscopic guidance (FG) with no clear evidence towards the more efficacious guidance technique. This study aims to systematically review the scientific literature to determine the clinical effectiveness of USG compared with FG-IACSIs for people with pain-related hip OA.</p><p><strong>Methods: </strong>A systematic review of major bibliographic databases from inception to 24 August 2023 was conducted. Randomised controlled trials of USG- and FG-IACSIs for patients with hip OA were included. The primary outcome measure was pain. Hedges' g calculated effect size and meta-analysis using the random-effects model-estimated pooled effect sizes. τ<sup>2</sup>, I<sup>2</sup> and Cochran's Q calculated heterogeneity. Network meta-analysis was completed to indirectly compare effect sizes. Quality was assessed using the Cochrane risk-of-bias tool (RoB2).</p><p><strong>Results: </strong>A total of 1464 citations were identified; eight studies were included in the review. No studies directly compared imaging modalities. Two network meta-analyses indirectly comparing USG- to FG-IACSI via an image-guided comparator hip injection ([any comparator], [local anaesthetic or saline]) established effect sizes (g) of 2.61 and 2.46, respectively, both in favour of FG-IACSI. Heterogeneity was low in the USG studies and high in the FG studies.</p><p><strong>Conclusion(s): </strong>Evidence suggests that both USG and FG-IACSI are effective at reducing pain at 1 month in patients with painful hip OA. Although network meta-analyses favoured FG-IACSI, further high-quality trials are needed to determine the preferred guidance technique.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70005"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orthosis Management in Knee Osteoarthritis: Evaluating Existing Recommendations and Achieving Consensus on Implementation Through the Delphi Method.","authors":"Zilan Bazancir-Apaydin","doi":"10.1002/msc.70018","DOIUrl":"https://doi.org/10.1002/msc.70018","url":null,"abstract":"<p><strong>Objective: </strong>The available evidence on orthosis management in the knee osteoarthritis (KOA) remains questionable. This study aims to evaluate existing recommendations and achieve consensus on their implementation through the modified Delphi method.</p><p><strong>Methods: </strong>Experienced experts in orthosis management for KOA patients participated in three Delphi rounds. Each round involved addressing various questions related to recommended orthosis type such as insole, knee brace, footwear, indications and contraindications, dosage of orthosis usage, follow-up period, long-term side effects, fitting, and weaning procedure. Consensus was defined as ≥ 70% agreement with a question.</p><p><strong>Results: </strong>Consensus was achieved for all questions. Experts frequently recommended custom-made insoles, neoprene knee braces, and appropriate footwear. The recommended duration of insole and knee brace usage averaged 3-6 months. Insole usage was advised during all weight-bearing activities, while knee braces were suggested for 4-6 h per day. Experts recommended orthosis follow-up for an average of 4-6 months. Reduced compliance with orthoses was highlighted by experts as the most significant long-term side effect. The fitting of orthoses is typically evaluated through gait analyses, assessment of symptoms and comfort, and observation of the corrective effects on impaired biomechanics in the clinical setting. Besides, experts commonly recommend a gradual weaning process from orthoses.</p><p><strong>Conclusions: </strong>This study addresses the existing lack of consensus on orthosis management in KOA and provides essential clinical practice recommendations from multidisciplinary experts.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70018"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Canzone, Federico Roggio, Antonino Patti, Valerio Giustino, Carmen Mannucci, Debora Di Mauro, Giuseppe Musumeci, Antonino Bianco, Fabio Trimarchi
{"title":"Classification of Physical Activity Programs Based on the Kellgren & Lawrence Scale for Knee Osteoarthritis: A Systematic Review.","authors":"Alberto Canzone, Federico Roggio, Antonino Patti, Valerio Giustino, Carmen Mannucci, Debora Di Mauro, Giuseppe Musumeci, Antonino Bianco, Fabio Trimarchi","doi":"10.1002/msc.70019","DOIUrl":"10.1002/msc.70019","url":null,"abstract":"<p><strong>Introduction: </strong>Knee osteoarthritis is a common orthopaedic disease, is the leading cause of disability in the elderly, and can lead to pain, loss of function, and reduced quality of life. This research aims to determine how PA programs can be effectively classified and customised to align with the stages of knee OA according to the KL classification.</p><p><strong>Objective: </strong>The research aims to fill the gap in understanding the relationship between the type and intensity of PA and the stages of OA as defined by the KL classification.</p><p><strong>Materials and methods: </strong>A systematic search was performed using PubMed, Web of Science, and Scopus databases. This review included different types of studies published after January 1, 2013.</p><p><strong>Results: </strong>Two thousand one hundred and thirty-six were picked up and only nine articles met the inclusion criteria. The beneficial effects of exercise were found in the function of the joints, pain, and quality of life. Aerobic, isometric, and resistance training showed positive effects and presented improvements in physical function, quality of life, and pain.</p><p><strong>Conclusion: </strong>The exercise programs appear to be both safe and effective in subjects with knee osteoarthritis with regard to quality of life, pain, and knee function.</p><p><strong>Trial registration: </strong>PROSPERO registration number: CRD42024550463.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70019"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11598803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stine Clausen, Jan Hartvigsen, Melker S Johansson, Lise Grethe Kjønø, Søren Grøn, Christian V Skovsgaard, Kjersti Storheim, Karin Magnusson, Margreth Grotle, Casper Nim
{"title":"Healthcare Utilisation in Danish Primary Care Among Patients With Low Back or Neck/Thoracic Spine Pain Before and After Assessment in Secondary Care.","authors":"Stine Clausen, Jan Hartvigsen, Melker S Johansson, Lise Grethe Kjønø, Søren Grøn, Christian V Skovsgaard, Kjersti Storheim, Karin Magnusson, Margreth Grotle, Casper Nim","doi":"10.1002/msc.70017","DOIUrl":"https://doi.org/10.1002/msc.70017","url":null,"abstract":"<p><strong>Objectives: </strong>To describe characteristics and primary healthcare utilisation in Danish patients with low back pain (LBP) or neck/thoracic spine pain (NTP) 8 years before and 2 years after assessment in secondary care.</p><p><strong>Methods: </strong>In this cohort study, we included patients aged ≥ 18 who were assessed at an outpatient spine clinic from 2013 to 2021 and linked self-reported information with national registry data. We calculated the prevalence of all-cause healthcare utilisation in primary care. Then, we determined changes in the number of consultations from before to after assessment in secondary care using generalised estimating equations.</p><p><strong>Results: </strong>We included 56,949 LBP patients and 18,926 NTP patients. The baseline characteristics were similar overall. For both LBP and NTP, all-cause healthcare utilisation increased slightly over time, with a substantial increase in the quarter before the secondary care assessment and a decrease after. Before the assessment, almost all patients consulted general practitioners (95%), while some consulted physiotherapists or chiropractors (60%). Overall, consultations decreased by 19% and 17% for patients with LBP and NTP from 12 to 1 month before to 1-12 months after the assessment. In contrast, 13-24 months after assessment, we found a slight increase in consultations in both groups compared to the same period before.</p><p><strong>Conclusions: </strong>Patients with LBP and NTP were similar and used similar primary healthcare, which slightly increased over the 10 years. As physiotherapists and chiropractors are first-line providers of guideline-recommended spine pain treatment, the finding that 40% did not consult these professions the year before the secondary care assessment indicates that not all patients receive recommended care before referral.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70017"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Proton Rahman, Marco Garrido-Cumbrera, Sherry Rohekar, Michael G Mallinson, Elie Karam, Algis V Jovaisas, Nigil Haroon, Jeff Beach, Artur J de Brum-Fernandes, Martin Cohen, Jonathan Chan, Jose Correa-Fernández, Patrick Leclerc, Robert D Inman
{"title":"Canadian Patients With Axial Spondyloarthritis Require Almost a Decade To Be Diagnosed Leading to Severe Functional Limitation. Results From the International Map of Axial Spondyloarthritis (IMAS).","authors":"Proton Rahman, Marco Garrido-Cumbrera, Sherry Rohekar, Michael G Mallinson, Elie Karam, Algis V Jovaisas, Nigil Haroon, Jeff Beach, Artur J de Brum-Fernandes, Martin Cohen, Jonathan Chan, Jose Correa-Fernández, Patrick Leclerc, Robert D Inman","doi":"10.1002/msc.70010","DOIUrl":"10.1002/msc.70010","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the sociodemographic characteristics and disease-related factors associated with diagnostic delay in Canadian patients with axial spondyloarthritis (axSpA).</p><p><strong>Methods: </strong>Data from 542 Canadian patients who participated in the International Map of Axial Spondyloarthritis online survey were analysed. Diagnostic delay was calculated as the difference between age at diagnosis and age at onset of the first symptoms reported by participants. Univariate and multivariate analyses were used to evaluate possible factors associated with diagnostic delay.</p><p><strong>Results: </strong>The mean age (± SD) of the surveyed participants was 44.3 ± 13.9 years and 63.1% were female. The average diagnostic delay was 9.0 ± 10.5 years (median, 5.0 years; interquartile range, 1.0-13.8). In the multivariate regression analysis, the three variables most strongly associated with longer diagnostic delay were use of nonsteroidal anti-inflammatory drugs (NSAIDs) (B = 2.991; 95% CI = 1.075-4.909), medium or high functional limitation (B = 1.541; 95%CI = 0.186-2.896), and number of HCPs seen before diagnosis (B = 1.524, 95%CI = 1.072-1.977).</p><p><strong>Conclusion: </strong>Diagnostic delay continues to be a barrier to optimal care for Canadian axSpA patients. Significant diagnostic delay, associated with a high number of HCP visits prior to diagnosis, high use of NSAIDs, and marked functional limitation in daily life, illustrate the convoluted axSpA patient journey.</p>","PeriodicalId":46945,"journal":{"name":"Musculoskeletal Care","volume":"22 4","pages":"e70010"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}