Journal of Family and Community Medicine最新文献

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Prevalence of internalized stigma in patients with psychiatric illness in Abha, Southern Region, Saudi Arabia. 沙特阿拉伯南部地区阿布哈精神病患者内部污名的患病率。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2023-04-01 Epub Date: 2023-04-12 DOI: 10.4103/jfcm.jfcm_222_22
Abdulmajeed A Zarbah, Hayfa A Al Alfard, Hassan S Alamri, Nada Al Edrees, Nouf S Alshahrani, Ali F Alshehri
{"title":"Prevalence of internalized stigma in patients with psychiatric illness in Abha, Southern Region, Saudi Arabia.","authors":"Abdulmajeed A Zarbah,&nbsp;Hayfa A Al Alfard,&nbsp;Hassan S Alamri,&nbsp;Nada Al Edrees,&nbsp;Nouf S Alshahrani,&nbsp;Ali F Alshehri","doi":"10.4103/jfcm.jfcm_222_22","DOIUrl":"10.4103/jfcm.jfcm_222_22","url":null,"abstract":"<p><strong>Background: </strong>Mental stigma occurs when patients with various mental disorders are labeled by their disorders. Little is known about the burden of mental stigma on patients with mental disorders. The aim of this study was to evaluate the incidence of mental stigma on patients with psychiatric disorder in Saudi Arabia.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted among previously diagnosed patients with any psychiatric disorder attending King Khalid Hospital, Abha, Saudi Arabia. The patients were interviewed with a sociodemographic questionnaire and a validated Arabic version of the Internalized Stigma of Mental Illness (ISMI-29) scale. Chi-square test and t-test were used to assess the association between various demographic characteristics and presence of stigma.</p><p><strong>Results: </strong>The study included 489 patients with different psychiatric disorders. The mean age of the participants was 32.8 years and 54.6% were females. About 39% participants showed no to minimal internalized stigma, 37.4% of total sample had mild stigma, 20% had moderate stigma, and 3.7% had severe stigma. A signficantly higher proportion (71.4%) of widowed patients had stigma (<i>P</i> = 0.032).</p><p><strong>Conclusion: </strong>Self-stigma is prevalent among patients with psychiatric disorders in Abha, Saudi Arabia, but lower than the prevalence in developing countries. Marital status has a significant impact on the prevalence and severity of the self-stigma of patients. There is a need for awareness program to reduce self-stigma. Psychiatric institutions should also focus on promotion of patients' social life and increase patient's awareness of certain issues that could prevent stigma.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"30 2","pages":"103-108"},"PeriodicalIF":2.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/27/da/JFCM-30-103.PMC10252634.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9611230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergency versus elective cholecystectomy: Experience at a university hospital in the Eastern Province, Saudi Arabia. 急诊与选择性胆囊切除术:沙特阿拉伯东部省一所大学医院的经验。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2023-01-01 Epub Date: 2022-12-29 DOI: 10.4103/jfcm.jfcm_116_22
Nasser M Amer, Mosab A Alarfaj, Sharifah A Othman, Shadi Alshammary, Eiman M Alshammari
{"title":"Emergency versus elective cholecystectomy: Experience at a university hospital in the Eastern Province, Saudi Arabia.","authors":"Nasser M Amer,&nbsp;Mosab A Alarfaj,&nbsp;Sharifah A Othman,&nbsp;Shadi Alshammary,&nbsp;Eiman M Alshammari","doi":"10.4103/jfcm.jfcm_116_22","DOIUrl":"10.4103/jfcm.jfcm_116_22","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic cholecystectomy (LC), the procedure of choice for treating most gallbladder pathology, has become the most trusted elective procedure for treating gallstone disease because of its effectiveness and safety. While the timing is an important factor in those cases, our aim in this study was to compare emergency and elective LC, determine the differences in postoperative complications, and assess the conversion rate to open cholecystectomy.</p><p><strong>Materials and methods: </strong>This study included a total of 627 patients who had undergone laparoscopic cholecystectomy during 2017-2019 at King Fahd Hospital of the University (KFHU). Records of both emergency and elective cases were reviewed from Quadra-med (software package). All demographic data of the patients, presenting complaint, laboratory and inflammatory marker, type of the operation, intraoperative complications, procedure time, conversion rate from laparoscopic to open cholecystectomy, postoperative period, length of hospital stay, and pathological diagnosis were entered into an Excel sheet. The data was analyzed using SPSS 23.0. Qualitative variables were described as frequencies and percentages, and continuous variables were summarized with mean and standard deviation (SD). Chi-square test, <i>t</i>-test, and the Mann-Whitney <i>U</i>-test were applied to test for statistical significance at <i>P</i> ≤ 0.05.</p><p><strong>Results: </strong>The mean age for patients undergoing elective LC was 39.94 years (SD=13.56) whereas, mean age of patients undergoing emergency LC was 40.64 years (SD=13.02). About 71% of cases in elective LC group were females compared to 55% in the emergency LC group. There was a significant difference in C-reactive protein (CRP) in relation to the type of surgery where <i>P</i> < 0.05. Twelve (1.9%) patients had subtotal cholecystectomy and two cases converted from LC to open. There was a significant association between postoperative complication and the type of surgery. The length of hospital stay (LOS) was also found to be significantly more in patients having emergency LC (6.0 vs. 4.5 d; <i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The relation between conversion to an open procedure and type of surgery (elective or emergency) in our study was nonsignificant. There was a significant association between preoperative CRP, postoperative complication, length of hospital stay, and type of surgery. Further multicenter studies are required for further investigation.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"30 1","pages":"37-41"},"PeriodicalIF":2.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/20/JFCM-30-37.PMC9954423.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10781258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arabic Abstracts 阿拉伯语摘要
Journal of Family and Community Medicine Pub Date : 2023-01-01 DOI: 10.4103/2230-8229.387733
{"title":"Arabic Abstracts","authors":"","doi":"10.4103/2230-8229.387733","DOIUrl":"https://doi.org/10.4103/2230-8229.387733","url":null,"abstract":"Log in or Register Get new issue alertsGet alerts Submit a Manuscript Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Register Login HomeCurrently selectedCurrent IssuePrevious IssuesFor Authors Information for AuthorsSubmit a Manuscript Published Ahead-of-PrintJournal Info About the JournalEditorial BoardAffiliated SocietyAdvertisingSubscriptionsReprintsRights and Permissions All Articles Images Videos Podcasts Blogs Advanced Search","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of body mass index compared to whole-body dual energy X-ray absorptiometry in diagnosing obesity in adults in the Eastern Province of Saudi Arabia: A cross-sectional study 体重指数与全身双能x线吸收仪在诊断沙特阿拉伯东部省成人肥胖中的准确性:一项横断面研究
Journal of Family and Community Medicine Pub Date : 2023-01-01 DOI: 10.4103/jfcm.jfcm_85_23
Amani M. Alqarni, Abdullah S. Aljabr, Moataza M. Abdelwahab, Ahmed H. Alhallafi, Mustafa T. Alessa, Abdullah H. Alreedy, Sara A. Elmaki, Naheel A. Alamer, Magdy A. Darwish
{"title":"Accuracy of body mass index compared to whole-body dual energy X-ray absorptiometry in diagnosing obesity in adults in the Eastern Province of Saudi Arabia: A cross-sectional study","authors":"Amani M. Alqarni, Abdullah S. Aljabr, Moataza M. Abdelwahab, Ahmed H. Alhallafi, Mustafa T. Alessa, Abdullah H. Alreedy, Sara A. Elmaki, Naheel A. Alamer, Magdy A. Darwish","doi":"10.4103/jfcm.jfcm_85_23","DOIUrl":"https://doi.org/10.4103/jfcm.jfcm_85_23","url":null,"abstract":"BACKGROUND: Obesity is a major health concern that requires accurate diagnosis and management. Body mass index (BMI) commonly used to diagnose obesity, has limitations in accurately assessing body fat. Body fat percentage (BF%) from whole-body dual energy X-ray absorptiometry (DEXA) scans is gaining popularity as a more accurate method in diagnosing obesity. MATERIALS AND METHODS: This cross-sectional study included 319 adult patients who underwent whole-body DEXA scans in the Eastern Province of Saudi Arabia from May 2016 to December 2021 were recruited from three medical centers, where data for whole-body DEXA were available. Body fat percent was obtained from the whole-body DEXA scan reports and were compared to BMI to evaluate prevalence of obesity. Data was extracted by reviewing patients’ records using a structured data collection tool. BMI was defined using WHO criteria, and diagnostic performance was assessed by estimating specificity, sensitivity, likelihood ratios, and predictive values, and by constructing receiver operating characteristic (ROC) curves for BMI to detect obesity by age group. RESULTS: The gender-specific BF% cutoff points revealed a higher prevalence of obesity than BMI cutoff points. BMI misclassified 40.6% of participants, and optimal cutoff points yielding highest area under the curve were 24 kg/m 2 and 24.3 kg/m 2 for males and females, respectively. CONCLUSION: The study underscores the importance of using accurate and comprehensive diagnostic tools such as whole-body DEXA scans to assess obesity.","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal cord compression secondary to intraspinal extramedullary hematopoiesis 脊髓压迫继发于椎管内髓外造血
Journal of Family and Community Medicine Pub Date : 2023-01-01 DOI: 10.4103/jfcm.jfcm_151_23
Foziah J. AlShamrani, Noor M. AlMohish, Fahad A. AlDawsari, Jaafer J. AlObaid, Ibrahim A. AlGhanimi, Abdullah A. AlNahdi
{"title":"Spinal cord compression secondary to intraspinal extramedullary hematopoiesis","authors":"Foziah J. AlShamrani, Noor M. AlMohish, Fahad A. AlDawsari, Jaafer J. AlObaid, Ibrahim A. AlGhanimi, Abdullah A. AlNahdi","doi":"10.4103/jfcm.jfcm_151_23","DOIUrl":"https://doi.org/10.4103/jfcm.jfcm_151_23","url":null,"abstract":"Extramedullary hematopoiesis (EMH) is a rare cause of spinal cord compression (SCC) occurring in various hematological illnesses such as myeloproliferative disorders, thalassemias, and various types of anemia. EMH represents the growth of blood cells outside the bone marrow. Common EMH locations include the spleen, liver, lymph nodes, and paravertebral regions. When this occurs in the spinal cord, the mass effect can compress the spinal cord and cause different neurological symptoms depending on the area of the spinal cord affected. This report describes a 27-year-old female with a known case of beta-thalassemia major, who presented with mid-thoracic back pain, weakness, and paresthesia at the T10 level. In addition, this report illustrates the importance of considering EMH in the differential diagnosis of SCC in patients with thalassemia.","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attention-deficit hyperactivity disorder in Egyptian medical students and how it relates to their academic performance 埃及医学生的注意力缺陷多动障碍及其与学习成绩的关系
Journal of Family and Community Medicine Pub Date : 2023-01-01 DOI: 10.4103/jfcm.jfcm_59_23
Eman M. Shebl, Noha M. Abu Bakr Elsaid, Hend A. Hassan, Doaa Kamal, Eman Araby
{"title":"Attention-deficit hyperactivity disorder in Egyptian medical students and how it relates to their academic performance","authors":"Eman M. Shebl, Noha M. Abu Bakr Elsaid, Hend A. Hassan, Doaa Kamal, Eman Araby","doi":"10.4103/jfcm.jfcm_59_23","DOIUrl":"https://doi.org/10.4103/jfcm.jfcm_59_23","url":null,"abstract":"BACKGROUND: The neurobehavioral disorder, known as attention-deficit hyperactivity disorder (ADHD), is characterized by impulsivity, hyperactivity, and a lack of focus. In addition, it is connected to poor academic performance. The purpose of this study was to determine the prevalence of ADHD and its effect on their academic performance among medical students. MATERIALS AND METHODS: This web-based cross-sectional study was conducted among medical students of four medical colleges during December 2021 and April 2022. Data was collected using a self-administered questionnaire comprising Wender Utah Rating Scale and adult ADHD Self-Report Scale [ASRS]. The link to Google Form survey was distributed to students through academic emails and WhatsApp. Data analyzed using SPSS; Chisquare test or Fisher’s exact test as appropriate, were used to determine statistical significance. RESULTS: A total of 990 students filled online questionnaire; 54.7% were females.. The estimated prevalence of ADHD in Egyptian medical students was 11%. Students who had childhood ADHD were significantly linked with the present ADHD ( r = 0.54, P < 0.001). There was a negative correlation between the ASRS score for ADHD and students’ GPA ( r = 0.2, P < 0.001). No statistically significant association was observed between ADHD and sex, type of university, and academic level. of the students. CONCLUSION: ADHD is prevalent among medical students. Since most of our students with adult ADHD also had preexisting childhood ADHD, it is crucial that the primary care services, especially school health services, have appropriate standards for the early identification and management of ADHD. Health authorities should conduct a comprehensive health education campaign to raise public awareness of ADHD and its risk factors, the clinical picture, and the burden.","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136307002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjustment disorder among first year medical students at King Saud University, Riyadh, Saudi Arabia, in 2020. 2020年,沙特阿拉伯利雅得沙特国王大学医学一年级学生的适应障碍。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2023-01-01 Epub Date: 2022-12-29 DOI: 10.4103/jfcm.jfcm_227_22
Fahad A Alhussain, Abdulhakim I Bin Onayq, Dawood H Ismail, Mohammed A Alduayj, Turki A Alawbathani, Mohammed A Aljaffer
{"title":"Adjustment disorder among first year medical students at King Saud University, Riyadh, Saudi Arabia, in 2020.","authors":"Fahad A Alhussain,&nbsp;Abdulhakim I Bin Onayq,&nbsp;Dawood H Ismail,&nbsp;Mohammed A Alduayj,&nbsp;Turki A Alawbathani,&nbsp;Mohammed A Aljaffer","doi":"10.4103/jfcm.jfcm_227_22","DOIUrl":"10.4103/jfcm.jfcm_227_22","url":null,"abstract":"<p><strong>Background: </strong>The general health and well-being of medical students has become a matter of concern, as medical students have higher levels of stress than their nonmedical peers. Long-standing stress may lead to serious outcomes, such as depression, anxiety, poor quality of life, or adjustment disorders. This study aimed to estimate the proportion of first year medical students who have adjustment disorder and explore possible risk factors.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted among all first-year medical students at King Saud University, College of Medicine, Saudi Arabia. The adjustment disorder-new model 20 (ADNM-20) was used to assess adjustment disorder with the stressor and item lists. The item list scores were summed and a cutoff point >47.5 was designated as a high risk of developing the disorder. Descriptive analysis included computing mean and standard deviation for continuous variable while frequency and percentages for categorical variables. Chi-square test and logistic regression analysis determined risk factors for having an adjustment disorder and the stress of attending a medical school.</p><p><strong>Results: </strong>The study enrolled 267 students but only 128 completed the ADNM-20 survey. Out of 267 students, the most commonly reported recent stressor was too much/too little work, and 52.8% reported having difficulty in meeting deadlines. The most common core symptom expressed by the medical students was avoidance behavior with a mean score of 10.91 ± 3.12, followed by preoccupation with stressors with a mean score of 10.66 ± 3.10. The factors significantly associated with having adjustment disorder were being female, younger age, recent illness of a loved one, having family conflicts, and having too much or too little work.</p><p><strong>Conclusion: </strong>First year medical students are at increased risk of adjustment disorder. Screening and awareness programs may be considered for preventing adjustment disorder. Increased student-staff interactions may provide support to adapt to their new environment and help reduce social adjustment difficulties.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"30 1","pages":"59-64"},"PeriodicalIF":2.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/2f/JFCM-30-59.PMC9954430.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10780820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A rare invasive male breast cancer of nonspecific type presenting at a primary care clinic: Importance of early diagnosis and management. 一种罕见的侵袭性男性癌症非特异性类型在初级保健诊所的表现:早期诊断和管理的重要性。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2023-01-01 Epub Date: 2022-12-29 DOI: 10.4103/jfcm.jfcm_210_22
Nurulhana S Mansoor, Farnaza Arifin, Noor K M Kornain, Mazuin M Razalli
{"title":"A rare invasive male breast cancer of nonspecific type presenting at a primary care clinic: Importance of early diagnosis and management.","authors":"Nurulhana S Mansoor,&nbsp;Farnaza Arifin,&nbsp;Noor K M Kornain,&nbsp;Mazuin M Razalli","doi":"10.4103/jfcm.jfcm_210_22","DOIUrl":"10.4103/jfcm.jfcm_210_22","url":null,"abstract":"<p><p>Male breast cancer is a rare disease with an incidence rate of <1% of all breast cancer cases, and only 1% of all male malignancies. Men tend to present at an older age and with more advanced stages compared to women. We report a case of a 74-year-old man who presented at a primary care clinic with a right subareolar painless breast mass. A mammogram and core biopsy were performed. A diagnosis of right invasive breast carcinoma was rendered. The patient underwent a right total mastectomy with ipsilateral axillary lymph node dissection, which revealed an invasive ductal carcinoma of no special type (NST). Chemotherapy, radiotherapy, and hormonal therapy were included in the adjuvant treatment plan. In this report, we discuss the important role of the primary care physician (PCP) in early diagnosis and referral for definitive management. The PCP also plays an essential role in the holistic care of male breast cancer patients, including the management of physical, psychological, social, and underlying chronic diseases.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"30 1","pages":"65-67"},"PeriodicalIF":2.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/70/JFCM-30-65.PMC9954424.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10792651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of sodium-glucose cotransporter-2 inhibitors on kidney outcomes in type 2 diabetes: A tertiary center experience 钠-葡萄糖共转运蛋白-2抑制剂对2型糖尿病肾脏结局的影响:三级中心经验
Journal of Family and Community Medicine Pub Date : 2023-01-01 DOI: 10.4103/jfcm.jfcm_111_23
Mohammed H. Tawhari, Raed A. Aldahash, Faisal M. Almutairi, Mahdi S. Albogami, Ahmad E. Rokon, Faisal A. Alsomali, Khaled H. Alanazi, Abdulrahman A. Alshehri, Talal H. Almutairi, Abdulrahman D. Alharbi, Rayan M. Alghamdi, Ibrahim H. Tawhari, Salih A. Bin Salih
{"title":"Impact of sodium-glucose cotransporter-2 inhibitors on kidney outcomes in type 2 diabetes: A tertiary center experience","authors":"Mohammed H. Tawhari, Raed A. Aldahash, Faisal M. Almutairi, Mahdi S. Albogami, Ahmad E. Rokon, Faisal A. Alsomali, Khaled H. Alanazi, Abdulrahman A. Alshehri, Talal H. Almutairi, Abdulrahman D. Alharbi, Rayan M. Alghamdi, Ibrahim H. Tawhari, Salih A. Bin Salih","doi":"10.4103/jfcm.jfcm_111_23","DOIUrl":"https://doi.org/10.4103/jfcm.jfcm_111_23","url":null,"abstract":"BACKGROUND: Diabetic nephropathy (DN) is a complication of chronic hyperglycemia associated with diabetes mellitus (DM). Several studies have demonstrated the positive impact of sodium-glucose cotransporter-2 (SGLT2) inhibitors on kidney outcomes. The objective of the study was to evaluate the effects of dapagliflozin, an SGLT2 inhibitor, on kidney outcomes in Saudi patients with type 2 DM. MATERIALS AND METHODS: Study included all Saudi patients with type 2 DM who visited our center from August 1, 2021, to July 31, 2022, and had been on dapagliflozin for at least 3 months. Data was abstracted through chart review for all patients included in the study. Paired t-test or Wilcoxon signed-rank test were used to compare the results before and after treatment for continuous variables and the McNemar test was used to compare the results for categorical data. RESULTS: Study included 184 Saudi patients with type 2 diabetes with a mean age of 61.32 years (SD=9.37). Dapagliflozin 10 mg/day significantly reduced hemoglobin A1C (HbA1C) from a mean (SD) of 9.00 to 8.40 ( P < 0.001). Among a subgroup of patients with significant proteinuria ( n = 83), dapagliflozin significantly reduced ACR from a median of 93.1 to 64.9 mg/g ( P = 0.001). Following treatment, the estimated glomerular filtration rate improved from a mean of 69.83 to 71.68 mL/min and the mean arterial pressure (MAP) fell from 90.03 to 89.06 mmHg, both were not statistically significant. Despite a statistically insignificant increase in the episodes of urinary tract infections (UTIs), the hospitalization rate declined. No episodes of amputations or ketoacidosis occurred during the study period. CONCLUSION: SGLT2 inhibitors had beneficial effects among Saudi patients with type 2 diabetes by improving diabetic control and lowering proteinuria. Dapagliflozin did not result in significant harm, including UTIs, amputations, and ketoacidosis.","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136306798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health-related quality of life and its association with the symptom score and the thyroid function status of patients with primary hypothyroidism on replacement therapy 原发性甲状腺功能减退患者接受替代治疗后的健康相关生活质量及其与症状评分和甲状腺功能状态的关系
Journal of Family and Community Medicine Pub Date : 2023-01-01 DOI: 10.4103/jfcm.jfcm_103_23
Merina Martin, Rani Subramaniyan, Dhukhabandu Naik, Lakshmi Ramamoorthy, Hmar T. Lalthanthuami
{"title":"Health-related quality of life and its association with the symptom score and the thyroid function status of patients with primary hypothyroidism on replacement therapy","authors":"Merina Martin, Rani Subramaniyan, Dhukhabandu Naik, Lakshmi Ramamoorthy, Hmar T. Lalthanthuami","doi":"10.4103/jfcm.jfcm_103_23","DOIUrl":"https://doi.org/10.4103/jfcm.jfcm_103_23","url":null,"abstract":"BACKGROUND: A number of patients with primary hypothyroidism have reduced health-related quality of life (HR-QoL), even with optimum thyroid hormone replacement therapy. This study aimed to assess the HR-QoL of patients with hypothyroidism under replacement therapy and identify its relationship with the symptom score and thyroid function status. MATERIALS AND METHODS: Using a cross-sectional study design, 175 hypothyroid patients under replacement therapy who visited the Endocrinology Outpatient Department of a tertiary care center were selected by convenient sampling technique. Data was collected using a structured data collection tool comprising, HR-QoL Short Form-36 questionnaire, and Zulewski’s clinical score. Inferential statistical analyses were performed using Mann–Whitney U , Kruskal–Wallis, and Karl–Pearson Correlation tests. RESULTS: The overall mean quality of life score was 44.22 ± 12.14, with a substantial decline in role functioning because of physical health. A significant negative correlation ( P < 0.05) was found between HR-QoL and hypothyroidism symptom score. A significant association was observed between participants’ HR-QoL and their dosage of thyroxine supplement ( P < 0.05,) but no association was found with thyroid function status. CONCLUSION: There was a substantial reduction in the quality of life of the patients despite being on thyroid replacement therapy and achieving euthyroid status. This underlines the importance of symptom reduction and hormone optimization to enhance the quality of life.","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136307000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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