Journal of Family and Community Medicine最新文献

筛选
英文 中文
A case report of Jarcho-Levin syndrome. Jarcho-Levin综合征1例报告。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2021-01-01 Epub Date: 2021-01-07 DOI: 10.4103/jfcm.JFCM_303_20
Bhamidipaty K Durgaprasad, Sonica Sharma, Payala Vijayalakshmi
{"title":"A case report of Jarcho-Levin syndrome.","authors":"Bhamidipaty K Durgaprasad,&nbsp;Sonica Sharma,&nbsp;Payala Vijayalakshmi","doi":"10.4103/jfcm.JFCM_303_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_303_20","url":null,"abstract":"<p><p>Jarcho-Levin syndrome (JLS) is a rare, congenital disorder, inherited in an autosomal recessive pattern, that represents a spectrum of clinical and radiographic abnormalities of the spine and chest. The present case report discusses two siblings, an 11 year old girl and a 6 year old boy, diagnosed as cases of JLS based on family history and clinical-radiological findings. The main features of the syndrome are shortness of stature with a spinal abnormality, multiple abnormal vertebral defects, and a small malformed \"fan-like\" or \"crab-like\" rib cage due to posterior fusion and anterior flaring of the ribs, leading to short-trunk dwarfism. The spinal and rib malformations result in a small thoracic cavity, not capable of accommodating the growing lungs, causing thoracic insufficiency resulting in severe cardiac and respiratory complications and frequent chest infections. The diagnosis is based on clinical and radiological findings, characteristic physical appearance, symptoms of thoracic insufficiency, family history, consanguineous parents, skeletal survey, or specialized genetic tests for mutations. Milder forms are compatible with life.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"28 1","pages":"55-58"},"PeriodicalIF":2.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/84/JFCM-28-55.PMC7927973.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25452209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Coronavirus disease (COVID-19) and healthcare delivery system. 冠状病毒病(COVID-19)和卫生保健服务系统。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2021-01-01 Epub Date: 2021-01-07 DOI: 10.4103/jfcm.JFCM_572_20
Fahad A Al-Muhanna, Ahmed A Alkuwaiti, Marwan J Alwazzeh
{"title":"Coronavirus disease (COVID-19) and healthcare delivery system.","authors":"Fahad A Al-Muhanna,&nbsp;Ahmed A Alkuwaiti,&nbsp;Marwan J Alwazzeh","doi":"10.4103/jfcm.JFCM_572_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_572_20","url":null,"abstract":"The leadership in family and community medicine should be at the forefront in formulating those changes. The real challenge is how to merge the various aspects of the modifications, including the site of the practice, the context of daily practice, and the organizational in order, to deliver these services to COVID‐19 patients, and how to develop a special program to prevent COVID‐19 transmission both at the individual level and in the community.[11,12]","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"28 1","pages":"63-64"},"PeriodicalIF":2.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/c2/JFCM-28-63.PMC7927965.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25452208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Associations between intimate partner violence and pregnancy complications: A cross-sectional study in India. 亲密伴侣暴力与妊娠并发症之间的关系:印度的一项横断面研究。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2021-01-01 Epub Date: 2021-01-07 DOI: 10.4103/jfcm.JFCM_256_20
Durga B Avanigadda, Ravisankar A Kulasekaran
{"title":"Associations between intimate partner violence and pregnancy complications: A cross-sectional study in India.","authors":"Durga B Avanigadda,&nbsp;Ravisankar A Kulasekaran","doi":"10.4103/jfcm.JFCM_256_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_256_20","url":null,"abstract":"<p><strong>Background: </strong>The high prevalence rates of violence of the intimate partner affects the maternal health of the woman that sometimes ends in maternal mortality as well as the possibility of an adverse effect on the newborn. The purpose of this study was to assess the prevalence and determinants of intimate physical and sexual intimate partner violence (IPV) on mothers and examine the association between IPV and pregnancy complications.</p><p><strong>Materials and methods: </strong>Data for the present study were retrieved from the National Family Health Survey-IV (2015-2016). In total, 79,729 women completed the domestic violence questions, but 24,882 were considered for this analysis. The study was restricted to currently married women aged 15-49 who had given birth to at least one child in the 5 years preceding the survey. The association between self-reporting pregnancy complications with the experience of IPV was examined using Chi-square test, followed by multivariate logistic regression.</p><p><strong>Results: </strong>The study findings show that IPV, specifically physical and sexual violence, are associated with pregnancy complications. The results show that 31.6% of the women had experienced some form of IPV. The factors associated with IPV included husband's alcohol habit, women who had witnessed parental violence, and women whose husbands had shown high marital controlling behavior. The high level of pregnancy complications was reported by women who had experienced sexual violence, emotional violence, and women whose husbands display three or more specific behaviors.</p><p><strong>Conclusion: </strong>Confidential screening for IPV and prompt referral to support services could be crucial in improving women's reproductive health.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"28 1","pages":"17-27"},"PeriodicalIF":2.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/06/8f/JFCM-28-17.PMC7927968.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25452200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Patient satisfaction with virtual clinic during Coronavirus disease (COVID-19) pandemic in primary healthcare, Riyadh, Saudi Arabia. 沙特阿拉伯利雅得,初级卫生保健中冠状病毒病(COVID-19)大流行期间患者对虚拟诊所的满意度。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2021-01-01 Epub Date: 2021-01-07 DOI: 10.4103/jfcm.JFCM_353_20
Khalid G Alharbi, Mohammed N Aldosari, Abdularhman M Alhassan, Khalid A Alshallal, Abdullah M Altamimi, Bader A Altulaihi
{"title":"Patient satisfaction with virtual clinic during Coronavirus disease (COVID-19) pandemic in primary healthcare, Riyadh, Saudi Arabia.","authors":"Khalid G Alharbi,&nbsp;Mohammed N Aldosari,&nbsp;Abdularhman M Alhassan,&nbsp;Khalid A Alshallal,&nbsp;Abdullah M Altamimi,&nbsp;Bader A Altulaihi","doi":"10.4103/jfcm.JFCM_353_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_353_20","url":null,"abstract":"<p><strong>Background: </strong>The novel coronavirus, officially known as COVID-19, was first reported in Wuhan, China in December of 2019. Since that time, medical services in Saudi Arabia have adapted to the situation by delivering medical care via virtual clinics. Therefore, the present study aimed to assess patients' level of satisfaction with virtual clinics during the COVID-19 pandemic in Saudi Arabia.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted among patients who had experienced virtual clinics in primary healthcare centers in Riyadh, Saudi Arabia. An online validated questionnaire was sent to all participants who had at least one virtual visit between March 2020 to July 2020. The data sought included demographics, level of satisfaction and questions related to their experience with virtual clinics. Computed frequencies and percentages for categorical variables, and median, mean, and standard deviation for continuous variables. Satisfaction scores were compared between groups using Mann-Whitney U test and Kruskal Wallis test.</p><p><strong>Results: </strong>A total of 439 patients completed the questionnaire (response rate 97.5%); 54% were male. The participants were divided into three age groups: 18-39, 40-59, and ≥60 years. Overall level of patients' satisfaction with virtual clinic was 68.1%. Factors statistically significantly associated with satisfaction included gender, age group and level of education (post-graduate and middle school) and being well-informed on the use of telemedicine. Specific age groups that were significant were 18-39 and 40-59 years; 50.2% of the males found telemedicine very convenient, compared to only 36.1% females. Family medicine clinics were the most commonly visited virtual clinics, whereas obstetrics and gynecology clinics were the least attended virtual clinics. The inability to meet the health-care professional face-to-face was reported by 53.8% as the most important disadvantage.</p><p><strong>Conclusion: </strong>This study shows a high level of satisfaction with virtual clinics in Saudi Arabia during the COVID-19 pandemic despite the service being relatively new in healthcare service in the country. Our study demonstrated that satisfaction was linked to age, gender, education and the type of clinic used.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"28 1","pages":"48-54"},"PeriodicalIF":2.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/14/JFCM-28-48.PMC7927967.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25452204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Erratum: "Comparative study of the efficacy and safety of intranasal azelastine hydrochloride and fluticasone furoate in the treatment of allergic rhinitis". 勘误:“鼻内用盐酸氮唑elastine和糠酸氟替卡松治疗变应性鼻炎的疗效和安全性的比较研究”。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2021-01-01 Epub Date: 2021-01-07 DOI: 10.4103/2230-8229.306433
{"title":"Erratum: \"Comparative study of the efficacy and safety of intranasal azelastine hydrochloride and fluticasone furoate in the treatment of allergic rhinitis\".","authors":"","doi":"10.4103/2230-8229.306433","DOIUrl":"https://doi.org/10.4103/2230-8229.306433","url":null,"abstract":"<p><p>[This corrects the article on p. 186 in vol. 27, PMID: 33354149.].</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"28 1","pages":"65"},"PeriodicalIF":2.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/76/c2/JFCM-28-65.PMC7927963.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25453094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender divides in the clinical profiles of patients with acute myocardial infarction at a tertiary care center in South India. 在印度南部三级保健中心急性心肌梗死患者的临床概况中存在性别差异。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2021-01-01 Epub Date: 2021-01-07 DOI: 10.4103/jfcm.JFCM_443_20
Neethu M George, Lakshmi Ramamoorthy, Santhosh Satheesh, Kumari M Jayapragasam
{"title":"Gender divides in the clinical profiles of patients with acute myocardial infarction at a tertiary care center in South India.","authors":"Neethu M George,&nbsp;Lakshmi Ramamoorthy,&nbsp;Santhosh Satheesh,&nbsp;Kumari M Jayapragasam","doi":"10.4103/jfcm.JFCM_443_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_443_20","url":null,"abstract":"<p><strong>Background: </strong>Early identification of myocardial infarction (MI) is a determinant in the provision of appropriate treatment modalities. The focus of the present study is on the identification of gender-based differences in risk factors, clinical manifestations, and coronary angiography findings in patients presenting with MI.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted among patients admitted with MI at a tertiary care center in South India during March 2016 to June 2017. Selected 120 male and 120 female consecutive patients admitted with acute MI, who had survived and been stabilized. Data was collected using a pre-tested structure data sheet. Appropriate parametric and nonparametric tests were used to analyze the data.</p><p><strong>Results: </strong>Participants were homogenous as regards age (<i>P</i> < 0.107); majority of men and women were from the rural areas. About 32.5% of the men interpreted the pain as due to a cardiac problem or indigestion, whereas 60.8% of the women thought it was fatigue/muscle pain. The self-interpretation or perception of pain in both genders was statistically significant (<i>P</i> < 0.001). Compared to the men, the females increasingly presented with atypical symptoms (<i>P</i> = 0.005). Regarding ST-elevated MI, male preponderance was noted (<i>P</i> = 0.004)). Considering the anatomical location of MI, the presentation of Inferior Wall Myocardial Infarction (IWMI) was predominant in females compared to men (<i>P</i> = 0.003). The majority of men had increased presentation of single-vessel disease compared to women (<i>P</i> = 0.02), whereas normal coronaries and double-vessel disease were found statistically significantly higher in females (<i>P</i> = 0.03 and <i>P</i> = 0.008, respectively).</p><p><strong>Conclusion: </strong>Public education is needed on the atypical presentations which are common with women than in men. The public should, therefore, be informed of those symptoms and how to recognize them so that they may seek medical care promptly.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"28 1","pages":"42-47"},"PeriodicalIF":2.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8a/90/JFCM-28-42.PMC7927970.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25452202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Screening for depression, anxiety, and obsessive-compulsive disorders among secondary school students in Al-Hasa Region, Saudi Arabia. 沙特阿拉伯Al-Hasa地区中学生抑郁、焦虑和强迫症筛查
IF 2.7
Journal of Family and Community Medicine Pub Date : 2021-01-01 Epub Date: 2021-01-07 DOI: 10.4103/jfcm.JFCM_386_20
Abdul S Khan, Ahmed H Alalawi, Mohammed H Alalawi, Hassan A Alsahaf, Mahdi S Albahrani, Fatimah A Alhasawi
{"title":"Screening for depression, anxiety, and obsessive-compulsive disorders among secondary school students in Al-Hasa Region, Saudi Arabia.","authors":"Abdul S Khan,&nbsp;Ahmed H Alalawi,&nbsp;Mohammed H Alalawi,&nbsp;Hassan A Alsahaf,&nbsp;Mahdi S Albahrani,&nbsp;Fatimah A Alhasawi","doi":"10.4103/jfcm.JFCM_386_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_386_20","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to determine the prevalence of anxiety, depression, and obsessive-compulsive disorder (OCD) and assess their severity in both male and female secondary school students.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted among secondary school students in Al Hasa region. A sample of student was selected using multi-stage sampling technique. Data were collected using valid self administered questionnaires (Patient Health Questionnaire 9, Anxiety Disorder 7, and Yale-Brown Obsessive-Compulsive scale). Study was approved by institutional ethical review committee, and informed consent was obtained from each participant. SPSS used for data entry and analysis. Chi-square test was used to test for statistical significance.</p><p><strong>Results: </strong>A total of 1783 of students, 930 males and 853 females, were enrolled in the study. The prevalence of depression, anxiety, and OCD was 76.2%, 49.9%, and 61.6%, respectively. Most of the diagnosed students had mild forms of the diseases, fewer had moderate form, and very few had severe forms. The most significant risk factor was gender, but other risk factors were significant for some of the diseases.</p><p><strong>Conclusion: </strong>The prevalence of the three diseases is high and significantly associated with gender. Further work is needed to evaluate this high prevalence and assess the severity of the diseases and other risk factors.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"28 1","pages":"28-34"},"PeriodicalIF":2.7,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/0d/JFCM-28-28.PMC7927964.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25452201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Prevalence of potentially inappropriate medication and its correlates in elderly hospitalized patients: A cross-sectional study based on Beers criteria. 老年住院患者潜在不适当药物的患病率及其相关性:基于Beers标准的横断面研究。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2020-09-01 Epub Date: 2020-09-25 DOI: 10.4103/jfcm.JFCM_175_20
Rishabh Sharma, Parveen Bansal, Ravinder Garg, Ravi Ranjan, Rakesh Kumar, Malika Arora
{"title":"Prevalence of potentially inappropriate medication and its correlates in elderly hospitalized patients: A cross-sectional study based on Beers criteria.","authors":"Rishabh Sharma,&nbsp;Parveen Bansal,&nbsp;Ravinder Garg,&nbsp;Ravi Ranjan,&nbsp;Rakesh Kumar,&nbsp;Malika Arora","doi":"10.4103/jfcm.JFCM_175_20","DOIUrl":"10.4103/jfcm.JFCM_175_20","url":null,"abstract":"<p><strong>Background: </strong>The increase in the prescription of potentially inappropriate medication (PIM) in older adults with significant health consequences is a global concern. This study aimed to determine the prevalence of PIM prescription in older adults as identified by Beers criteria 2015 and 2019.</p><p><strong>Materials and methods: </strong>A cross-sectional study was carried out in older adults aged >65 years at a tertiary care postgraduate teaching hospital. All patients aged ≥65 years irrespective of their gender, admitted in the medical ward of the hospital with single/multiple comorbidities, and prescribed at least one daily medication, were included in the study. Data of patient history, patient case sheet, medication charts, laboratory reports, as well as radiological examinations test reports were retrieved from their files and were captured in a prevalidated data collection form. SPSS used for data analysis; multivariate logistic regression was used to determine the predictors of PIM prescribing and odds ratios (ORs) and 95% confidence intervals for ORs were computed.</p><p><strong>Results: </strong>Study included 323 patients; 61.3% were male, 74% patients were 65-70 years of age, and 78% patients were illiterate. The overall prevalence of PIM uses according to the Beers criteria 2015 and 2019 was 60.1% and 61.9%, respectively. No association found between PIMs prescribes and diagnosis category. Male gender, age 76-80 years, and education 10-12th class were found to be significantly related to PIM prescription.</p><p><strong>Conclusion: </strong>This study reflects a critical view of noncompliance of Beers criteria for geriatric healthcare even in tertiary care hospitals in India. Creatinine clearance rate should be kept in view when prescribing medicines for elderly inpatients.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"27 3","pages":"200-207"},"PeriodicalIF":2.7,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a4/96/JFCM-27-200.PMC7745783.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38743520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
A rare case of intraductal papilloma with atypical ductal hyperplasia in a male breast: A pathological diagnosis. 一例罕见的男性乳腺导管内乳头状瘤伴不典型导管增生:病理诊断。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2020-09-01 Epub Date: 2020-09-25 DOI: 10.4103/jfcm.JFCM_230_20
Sushma Bharti, Jyotsna Naresh Bharti, Jeewan Ram Vishnoi, Arsha B Soudamini
{"title":"A rare case of intraductal papilloma with atypical ductal hyperplasia in a male breast: A pathological diagnosis.","authors":"Sushma Bharti,&nbsp;Jyotsna Naresh Bharti,&nbsp;Jeewan Ram Vishnoi,&nbsp;Arsha B Soudamini","doi":"10.4103/jfcm.JFCM_230_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_230_20","url":null,"abstract":"<p><p>Male breast cancer is itself a very rare condition and represents 0.5%-1% of all breast cancers diagnosed. Atypical ductal hyperplasia (ADH), intraductal papilloma (IP), and ductal carcinoma <i>in situ</i> are also very rare in a male breast. Only a few cases of ADH with gynecomastia have been reported in English literature until now. Here, we report a rare case of an IP with ADH associated with gynecomastia in an elderly male, who complained of right nipple pain, discharge, and tiny retroareolar mass. Mammography showed a subareolar nodule graded as the Breast Imaging-Reporting and Data System 4B. It is difficult to differentiate, both clinically and radiologically, between benign and malignant papillary lesions and invasive carcinoma, because of the similarity of findings. Hence, any male with palpable unilateral hard fixed lesions in the retroareolar region with complaints of nipple discharge, skin changes, or axillary lymphadenopathy should have a histopathological evaluation.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"27 3","pages":"216-218"},"PeriodicalIF":2.7,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8e/d0/JFCM-27-216.PMC7745788.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39079606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparative study of the efficacy and safety of intranasal azelastine hydrochloride and fluticasone furoate in the treatment of allergic rhinitis. 盐酸氮卓斯汀和糠酸氟替卡松治疗过敏性鼻炎的疗效和安全性比较研究。
IF 2.7
Journal of Family and Community Medicine Pub Date : 2020-09-01 Epub Date: 2020-09-25 DOI: 10.4103/jfcm.JFCM_103_20
Nandish Chennakeshavaraju, Sarala Narayana, Azeem S M Mohiyuddin
{"title":"Comparative study of the efficacy and safety of intranasal azelastine hydrochloride and fluticasone furoate in the treatment of allergic rhinitis.","authors":"Nandish Chennakeshavaraju,&nbsp;Sarala Narayana,&nbsp;Azeem S M Mohiyuddin","doi":"10.4103/jfcm.JFCM_103_20","DOIUrl":"https://doi.org/10.4103/jfcm.JFCM_103_20","url":null,"abstract":"<p><strong>Background: </strong>Allergic rhinitis (AR) is characterized by nasal itch, sneezing, watery or mucous rhinorrhea, nasal obstruction, and nasal or pharyngeal irritation. If untreated, AR can impair patients' quality of life (QOL). Azelastine hydrochloride (AH), histamine receptor antagonists, has anti-inflammatory and mast cell stabilizing properties. Fluticasone furoate (FF) is an anti-inflammatory agent with action on mast cells, eosinophils, neutrophils, macrophages, and lymphocytes. This study compares the efficacy and safety of these medications in AR.</p><p><strong>Materials and methods: </strong>Patients in the study had been clinically diagnosed with AR. In each group, there were 75 randomized patients who were to receive either FF (27.5 μg/spray) or AH (0.10%) intranasally twice daily. Assessment in terms of symptoms (total nasal symptom score), signs (endoscopic staging), QOL, eosinophil count, and sensory attributes was done at baseline, day 7, and day 15. Adverse effects were recorded, and the cost incurred was analyzed. Paired and umpaired <i>t</i>-test were used to compare symptom scores, QOL scores, and absolute eosinophil count within and between the groups, respectively.</p><p><strong>Results: </strong>The total number of patients was 150 (76 males and 74 females); the mean age for FF group was 26.23 ± 5.2 years, and 26.96 ± 4.8 years for AH group. By day 7, there was a reduction of all scores in both medications, but the reduction in reduction was highly significant with FF (<i>P</i> = 0.001). There was a significant reduction (<i>P</i> = 0.001) in absolute eosinophil count both in blood and nasal smears by day 15 in both the groups; the reduction was significant (<i>P</i> = 0.001) with fluticasone. Adverse reactions were reported by 33.3% of patients receiving FF and 28% patients receiving AH.</p><p><strong>Conclusion: </strong>Fluticasone furoate produced sustained relief of symptoms, signs, and sensory attributes with a greater reduction in eosinophil count in comparison with AH in patients with allergic rhinitis.</p>","PeriodicalId":46862,"journal":{"name":"Journal of Family and Community Medicine","volume":"27 3","pages":"186-191"},"PeriodicalIF":2.7,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/37/JFCM-27-186.PMC7745787.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38743518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信