Australasian Medical Journal最新文献_第10页

Acupuncture treatment for sleep disturbances patients: A case report with inflammatory cytokine levels evaluation 针刺治疗睡眠障碍患者:1例炎症细胞因子水平评估报告

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2017.3304

Y. Kim

引用次数: 0

Clinical insights on Tolosa Hunt syndrome: A multidisciplinary approach on neurological-related symptomatology in maxillofacial region Tolosa Hunt综合征的临床观察:颌面部神经相关症状学的多学科方法

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3351

Z. Khan, Ammar Ahmed Siddiqui, J. Syed, Hamoud Aziz Alanizy, A. Cicconetti, A. Orefici, G. Falisi, F. Inchingolo, P. Bollero

引用次数: 0

Splenectomy in non-traumatic diseases 脾切除术在非创伤性疾病中的应用

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/amj.2018.3386

C. Gomes, Cléber Soares Júnior, F. Coccolini, G. Montori, Alice Assumpção Soares, Celio Pereira Junior, Flavio Vieira Marques Filho, P. Mendonca, Felipe Couto Gomes

{"title":"Splenectomy in non-traumatic diseases","authors":"C. Gomes, Cléber Soares Júnior, F. Coccolini, G. Montori, Alice Assumpção Soares, Celio Pereira Junior, Flavio Vieira Marques Filho, P. Mendonca, Felipe Couto Gomes","doi":"10.21767/amj.2018.3386","DOIUrl":"https://doi.org/10.21767/amj.2018.3386","url":null,"abstract":"Splenectomy represents the first choice for treatment of spontaneous splenic rupture, abscesses, cysts, tumours, and an alternative for control of hereditary, autoimmune, and myeloproliferative disorders. However, its relative indications have been reviewed for better understanding of both the primary affections and of splenectomy per se, particularly with regard to the immune system. The emergence of minimally invasive surgery, the possibility of splenic preservation, and availability of biological therapy has shown that the procedure has often been referred to as salvage therapy upon failure of other therapeutic propositions. On the other hand, patients have their general health status compromised by the underlying disease, by the use corticosteroids or biologic therapy, immunosuppressed, coagulation disorders, which contribute to the incidence of postoperative complications, such as infections, bleeding and venous thrombosis. Therefore, this scenario favours higher morbidity and mortality rates than those of other intra-abdominal surgical procedures. Thus, this review has the primary and comprehensive objective of purpose the best moment for splenectomy, when surgeons can interfere in the natural course of the disease increasing patients’ quality of life and survival. In short, it is desired that the surgeon has complete knowledge of the profound physiological changes imposed on the host. In addition, to distinguish when it is curative and mandatory from when it must be put on hold due to other non-operative treatments with similar outcomes and, lastly, when it is not recommended for not aggregating survival.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"617 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68184645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Neuron- specific enolase level in patients with metabolic syndrome and its value forecasting acute stroke 代谢综合征患者神经元特异性烯醇化酶水平及其对急性卒中的预测价值

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2018.3353

O. Ospanov, K. Ospanova, I. Kadyrova

{"title":"Neuron- specific enolase level in patients with metabolic syndrome and its value forecasting acute stroke","authors":"O. Ospanov, K. Ospanova, I. Kadyrova","doi":"10.21767/AMJ.2018.3353","DOIUrl":"https://doi.org/10.21767/AMJ.2018.3353","url":null,"abstract":"Background Patients with metabolic syndrome are at a greater risk of experiencing a cerebrovascular event. Several studies show that patients with metabolic syndrome have asymptomatic ischemic brain injury. In this case, there is a need for rapid determination of asymptomatic brain lesions and prediction of acute stroke. Aims The aim of the study was to determine the neuron-specific enolase (NSE) serum level in patients with metabolic syndrome and the value of this level for forecasting acute stroke. Methods The study used the following information to determine metabolic syndrome: waist circumference, total cholesterol, triglycerides, high-density lipoprotein cholesterol, blood pressure, and blood glucose. Doppler sonography mapping of the brachiocephalic trunk was held to determine the percentage of the carotid artery stenosis. To determine asymptomatic ischemic brain injury, the NSE serum marker was measured. Statistical processing of the measurements was performed using the H test and the Mann–Whitney test. The possible link between MS and NSE were determined by logistic regression analysis. Mathematical modeling was performed using logistic regression. Results There are statistically significant differences in NSE concentrations in groups with metabolic syndrome and ischemic stroke patients. This assertion is confirmed by logistic regression analysis, which revealed the existence of a relationship between metabolic syndrome and increased concentration of NSE. Conclusion Patients with metabolic syndrome have an increased concentration of NSE. This indicates the presence of asymptomatic ischemic neuronal damage. A prognostic model for determining the probability that patients with metabolic syndrome will have an acute stroke was developed.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68184698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Bilateral complete ureteral duplication with fixed dumbbell stone formation in the ureterocele 双侧输尿管完全复制伴输尿管囊肿内固定哑铃状结石形成

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/amj.2018.3366

S. Vahidi, P. Shadpour, N. Narimani, S. Haghdani

引用次数: 0

Sinus histiocytosis with massive lymphadenopathy, (Rosai-Dorfman Disease) with cholastatic jaundice in an HIV positive patient 窦性组织细胞增多症伴大量淋巴结病变，(Rosai-Dorfman病)伴胆汁淤积性黄疸

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/amj.2018.3456

K. Mpho, Elnagar Ali Ahmed, Mashoshoe Kgataki Sam, T. Preetha, Ngwata Portia, Bida Mishack

引用次数: 0

Systems multiple molecule drug design with less side-effects via drug data mining and genome-wide data identification 通过药物数据挖掘和全基因组数据识别，系统设计副作用小的多分子药物

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/amj.2018.3439

Bor-Sen Chen

{"title":"Systems multiple molecule drug design with less side-effects via drug data mining and genome-wide data identification","authors":"Bor-Sen Chen","doi":"10.21767/amj.2018.3439","DOIUrl":"https://doi.org/10.21767/amj.2018.3439","url":null,"abstract":"Background Drugs fail in the clinic for two main reasons; one is that they do not work and another is that they are not safe. As such, two of the most important steps in developing new drugs should be drug targets identification and side-effect validation. Aims The identification of drug targets and their restoration of cellular dysfunctions to normal cellular functions with less side-effects are considered as drug design specifications of systems medicine discovery. Since the effect on the normal expression of house-keeping genes and proteins is also considered as a restriction on drug design, the proposed multi-molecules drug strategy might be helpful for systems drug design with less-side effects. Methods By systems biology method, genetic and epigenetic networks (GENs) are constructed to identify network biomarker for drug targets of diseases by genome-wide high throughput data. An integration of computational networkbased approach for multiple drug targets with drug data mining is also proposed for systems drug discovery with more precise medicine and less side-effects. Finally, some systematic drug design specifications for drug design are proposed to restore to the normal functions of multiple drug targets with less side-effects. Results A systematic method is introduced to find multiple drug targets based on pathogenic mechanism investigated by network identification through genome-wide highthroughput data. Then a multi-molecule drug design strategy is also proposed to select a set of multi-molecule drugs with less side-effects via drug data mining method. Conclusion Systematic engineering design methods seem applicable to systems drug discovery and design.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68185437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Barriers to support nurses as second victim of medical errors: A qualitative study 支持护士作为医疗事故第二受害者的障碍:一项定性研究

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/amj.2018.3515

Z. Mokhtari, M. Hosseini, H. Khankeh, M. Fallahi-khoshknab, A. N. Nasrabadi

{"title":"Barriers to support nurses as second victim of medical errors: A qualitative study","authors":"Z. Mokhtari, M. Hosseini, H. Khankeh, M. Fallahi-khoshknab, A. N. Nasrabadi","doi":"10.21767/amj.2018.3515","DOIUrl":"https://doi.org/10.21767/amj.2018.3515","url":null,"abstract":"Background Given the inevitability of medical errors and their impact on health workers, providing support to those who suffer is vital for their physical and mental recovery. Identifying the barriers to obtaining support is imperative in this regard. Aims The current study was conducted to identify the barriers regarding supporting nurses as second victims of nursing errors in clinical settings in Iran. Methods This qualitative study was conducted with a sample, which was included 18 nurses. The subjects were selected through the purposive sampling method, and data were collected using in-depth and semi-structured interviews. The data were analysed using methods as described by Graneheim and Lundman (citation needed). The research context included the general and specialized departments of hospitals in Tehran, Iran, during 2017. Results According to the results, mismanagement, Cultural barriers, inadequate information, and Legal barriers were the main barriers to supporting nurses. Conclusion Training nurses about the second victim phenomenon is recommended as well as the methods to manage the effects of this phenomenon, the supportive resources, and legal issues.","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68186868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Updated meta-analysis of the relation between heart disease and androgenic alopecia or alopecia areata 心脏病与雄激素性脱发或斑秃关系的最新meta分析

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/amj.2017.3270

M. Amamoto, Tomohide Yamada, K. Hara

{"title":"Updated meta-analysis of the relation between heart disease and androgenic alopecia or alopecia areata","authors":"M. Amamoto, Tomohide Yamada, K. Hara","doi":"10.21767/amj.2017.3270","DOIUrl":"https://doi.org/10.21767/amj.2017.3270","url":null,"abstract":"Background The relationship between baldness and heart disease is still controversial. We performed an updated meta-analysis of observational studies to evaluate the relation between heart disease and androgenic alopecia or alopecia areata. Aims To evaluate the relation between heart disease and androgenic alopecia or alopecia areata. Methods Studies were identified by searching Medline and Embase up to October 20, 2017 without language restriction. Metaanalysis was performed by using a random-effects model. Results Nine studies were included in the meta-analysis (eight on androgenic alopecia and one on alopecia areata: 44,806 participants). Compared to men without baldness, men with androgenic alopecia had an increased risk of heart disease (relative risk (RR): 1.32, 95 per cent CI: 1.08 to 1.63, p=0.01, I 2 =25 per cent), and younger men (<55 or ≤60 years) showed a stronger association (RR: 1.44, 95 per cent CI: 1.11 to 1.86, p=0.01, I 2 =0 per cent). The positive relation depended on the severity of baldness and decreased in order of severe vertex (RR: 1.60, 95 per cent CI: 1.19 to 2.16, p=0.002), moderate vertex (RR: 1.41, 95 per cent CI: 1.22 to 1.64, p<0.001), mild vertex (RR: 1.18, 95 per cent CI: 1.05 to 1.33, p=0.007), and frontal baldness (RR: 1.10, 95 per cent CI: 0.92 to 1.32, p=0.28)). In contrast, there was no significant relation between alopecia areata and heart disease (RR: 0.91, 95 per cent CI: 0.60 to 1.39, p=0.66).","PeriodicalId":46823,"journal":{"name":"Australasian Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68182960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The effects of aerobic exercise on cognitive performance and sleep quality haemodialysis patients 有氧运动对血液透析患者认知表现和睡眠质量的影响

Australasian Medical Journal Pub Date : 2018-01-01 DOI: 10.21767/AMJ.2017.3279

Leila Poorsaadet, P. Soltani, K. Ghassami, B. Kohansal, M. Ahmadlou

引用次数: 3