ARYA Atherosclerosis最新文献_第9页

Evaluation of the prevalence and predictors of right ventricular diastolic dysfunction in patients undergoing coronary artery bypass surgery. 冠状动脉搭桥手术患者右心室舒张功能不全的患病率及预测因素的评估。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.41897.2907

Jamshid Abedi, Mohammad Ebrahim Ghafari, Jalal Kheirkhah, Hassan Moladoust, Mohammad Reza Aghajankhah

{"title":"Evaluation of the prevalence and predictors of right ventricular diastolic dysfunction in patients undergoing coronary artery bypass surgery.","authors":"Jamshid Abedi, Mohammad Ebrahim Ghafari, Jalal Kheirkhah, Hassan Moladoust, Mohammad Reza Aghajankhah","doi":"10.48305/arya.2024.41897.2907","DOIUrl":"10.48305/arya.2024.41897.2907","url":null,"abstract":"Background: With the increase in the number of coronary artery bypass grafting (CABG) surgeries, the concern about complications after it has also increased. RV diastolic dysfunction (RVDD) is one of the post-CABG complications, and in this study, we intend to investigate its frequency and predictors.Methods: In this cross-sectional study, eighty CABG candidate adult patients were included. A history of previous heart surgery or arrhythmia were the main exclusion criteria. After recording demographic and clinical information, echocardiography of the right ventricle (RV) was performed the day before the surgery and seven days later. The functional parameters were obtained according to the Guidelines for the Echocardiographic Assessment of the Right Heart in Adults.Results: Eighty patients with an average age of 60.25 ± 8.93 years participated in the study. Most patients were male (72.5%). Thirteen patients had RVDD before CABG (30.8% grade I and 69.2% grade II). All these 13 patients had RVDD grade II after surgery (P=0.046). Among 67 patients with normal RV function before CABG, RV function was normal in only 20 patients (29.9%) after CABG. The incidence of grade I and grade II post-CABG RVDD (post-coronary artery bypass grafting right ventricle diastolic dysfunction) was 11.9% and 58.2%, respectively (P<0.001). Univariate logistic regression analysis showed that there was no association between pre-CABG variables, neither demographic nor echocardiographic, and the occurrence of RVDD after CABG.Conclusion: CABG surgery is associated with a high incidence of RVDD, which cannot be predicted before surgery. The short-term and long-term consequences of this complication are still unknown.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 3","pages":"21-27"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coronary artery calcification score as the determinant of coronary artery disease in chronic kidney disease patients: A preliminary study. 冠状动脉钙化评分作为慢性肾病患者冠状动脉病变的决定因素：初步研究

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2023.39234.2832

Maryam Moradi, Ali Talebi, Sara Shavakhi, Mohammad Javad Tarrahi, Fouad Meraji Far

{"title":"Coronary artery calcification score as the determinant of coronary artery disease in chronic kidney disease patients: A preliminary study.","authors":"Maryam Moradi, Ali Talebi, Sara Shavakhi, Mohammad Javad Tarrahi, Fouad Meraji Far","doi":"10.48305/arya.2023.39234.2832","DOIUrl":"10.48305/arya.2023.39234.2832","url":null,"abstract":"Background: Coronary computed tomography angiography (CCTA) is a noninvasive cardiovascular imaging procedure that visualizes coronary artery calcifications (CAC), a marker of subclinical atherosclerosis. Due to different calcification patterns in patients with chronic kidney disease (CKD) compared to the general population, this study aims to present diagnostic cut-off values for CAC to detect early coronary artery disease (CAD) in CKD patients.Methods: This cross-sectional study included 807 patients: 407 with CKD and 400 controls with normal kidney function who underwent CCTA during 2019-2021. CAC score measurements were performed for all left main coronary arteries to investigate CAD. The Coronary Artery Disease Reporting and Data System (CAD-RADS) was used as the gold standard to determine the value of CAC, and diagnostic values were measured.Results: The number of female patients was 443 (54.9%), and 364 (45.1%) were male. The mean age in the case group was 63.95 ± 10.26 years, and in the control group, it was 53.80 ± 11.84 years. At the cut-off point of 85, the CAC score had a sensitivity and specificity of 84.7% and 83%, respectively, among patients with CKD to detect CAD (Area Under the Curve (AUC): 0.919, 95% CI: 0.89-0.94; P-value < 0.001). Considering a cut-point of 85 for CAC, the frequency of healthy subjects with CAD-RADS less than two was significantly higher than the cases (P-value = 0.012), while the two groups were similar regarding CAD-RADS 3-5 (P-value = 0.83).Conclusion: According to this study, the CAC score is a valuable means to detect CAD among CKD subjects. There is no significant difference in CAC between patients with substantial CAD-RADS in CKD and non-CKD patients. The cut-point of 85 for the CAC score was found valuable to diagnose CAD with over 80% sensitivity and specificity.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 3","pages":"12-20"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed coronary air embolism post re-do mitral valve replacement: A case report. 二尖瓣置换术后迟发性冠状动脉空气栓塞1例。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.41928.2910

Pouya Nezafati, Sumit Yadav

引用次数: 0

Effects of high intensity interval vs. low intensity continuous training on LXRβ, ABCG5 and ABCG8 genes expression in male wistar rats. 高强度间歇与低强度连续训练对雄性wistar大鼠LXRβ、ABCG5和ABCG8基因表达的影响

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42635.2961

Sediqeh Jalali

{"title":"Effects of high intensity interval vs. low intensity continuous training on LXRβ, ABCG5 and ABCG8 genes expression in male wistar rats.","authors":"Sediqeh Jalali","doi":"10.48305/arya.2024.42635.2961","DOIUrl":"10.48305/arya.2024.42635.2961","url":null,"abstract":"Background: Liver X receptors (LXR) play an essential role in the regulation of cholesterol metabolism, and their activation increases ABCG5 and ABCG8 gene expression for the improvement of cholesterol excretion from the body during reverse cholesterol transport (RCT). The aim of this study was to investigate the effects of high-intensity interval (HIT) and low-intensity continuous (LIT) trainings on gene expression of these substances after a high-fat diet in Wistar rats.Methods: Fifteen male Wistar rats were divided into 3 groups: control group (n = 5), HIT exercise group (n = 5), and LIT exercise group (n = 5). All groups were fed a high-fat diet for 13 weeks, and the HIT and LIT groups performed the specific training program. The expression of LXRβ, ABCG5, and ABCG8 genes was measured after the training period.Results: Data analysis showed significantly higher levels of LXRβ, ABCG5, and ABCG8 gene expression in the HIT and LIT groups compared to the control group (P ≤ 0.05).Conclusion: HIT and LIT trainings after a high-fat diet have beneficial effects on RCT, preventing heart attacks. Additionally, HIT training may have a greater effect on cholesterol excretion during the reverse cholesterol transport mechanism than LIT.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 6","pages":"27-33"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-hospital mortality of acute ST-elevation myocardial infarction (STEMI) and its predictors-using Yazd Cardiovascular Diseases Registry, YCDR. 急性st段抬高型心肌梗死（STEMI）的住院死亡率及其预测因子——基于Yazd心血管疾病登记处（YCDR）

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42893.2985

Mohsen Mohammadi, Seyedeh Mahdieh Namayandeh, Masoud Mirzaei, Mohsen Askari Shahi, Seyed Mahmoud Sadr Bafighi, Hamidreza Dehghan

{"title":"In-hospital mortality of acute ST-elevation myocardial infarction (STEMI) and its predictors-using Yazd Cardiovascular Diseases Registry, YCDR.","authors":"Mohsen Mohammadi, Seyedeh Mahdieh Namayandeh, Masoud Mirzaei, Mohsen Askari Shahi, Seyed Mahmoud Sadr Bafighi, Hamidreza Dehghan","doi":"10.48305/arya.2024.42893.2985","DOIUrl":"10.48305/arya.2024.42893.2985","url":null,"abstract":"Background: The purpose of this study was estimate and identify in hospital mortality predictors factors for patients with acute ST elevation myocardial infarction (STEMI).Methods: This study is a retrospective cohort study based on data from the Yazd Cardiovascular Diseases Registry (YCDR) from 2015-2018 in Yazd Province, Iran, focusing on hospitalized patients with ST-elevation myocardial infarction (STEMI). The primary outcome was in-hospital mortality in STEMI patients. A total of 1861 patients with STEMI were analyzed. Multivariable logistic regression was used to determine death predictive factors for in-hospital mortality in STEMI patients. The significance level of the model was considered to be 5% and the software was used for analysis.Results: The study included 1,861 patients with STEMI. Among them, 103 (5.5%) individuals died during admission the hospital. After multivariable logistic regression, the following variables were identified as death predictive factors for in-hospital mortality of STEMI: having a history of CVA (OR: 5.6, 95% CI: 2.2-20.3), killip class IV (OR: 6.4, 95%CI: 1.5-11.2), lower ejection fraction (OR: 3.6, 95% CI: 1.2-9.8), lower HDL cholesterol (OR: 1.2, 95% CI: 1.01-2.3), and lower hemoglobin (OR: 1.4, 95% CI: 1.3-2.9).Conclusion: This study found that lower ejection fraction, lower hemoglobin levels, Killip class IV, having a history of CVA, and low HDL cholesterol levels are important death predictive factors for hospital mortality in patients with STEMI. Health policy in STEMI management must consider these factors to improve hospital prognosis.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 6","pages":"6-16"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A cross-sectional analysis on hypertension: Exploring the impact of lifestyle modifications and antihypertensive drug adherence in Sudan. 高血压横断面分析：探讨苏丹生活方式改变和抗高血压药物依从性的影响。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42582.2952

Amani Ahmed, Hind A Rikabi, Samreen Soomro, Abd El-Karim Em, S H Estabrag, Ali Elham A

{"title":"A cross-sectional analysis on hypertension: Exploring the impact of lifestyle modifications and antihypertensive drug adherence in Sudan.","authors":"Amani Ahmed, Hind A Rikabi, Samreen Soomro, Abd El-Karim Em, S H Estabrag, Ali Elham A","doi":"10.48305/arya.2024.42582.2952","DOIUrl":"10.48305/arya.2024.42582.2952","url":null,"abstract":"Background: Sudan has a high prevalence of hypertension or high blood pressure, a key risk factor for cardiovascular illnesses. Therefore, this study aimed to investigate the socio-demographic characteristics, antihypertensive medication adherence, lifestyle changes, and the relationships between these factors and blood pressure control.Methods: A cross-sectional study was conducted from March to August 2023 in tertiary care hospitals in Sudan. A structured questionnaire was used to gather information from 385 hypertensive individuals who participated in the study.Results: The results estimated a positive correlation between the independent variables measuring medication adherence. Diet, stress management, and exercise also moderately correlated with each other and the independent variables. Systolic and diastolic blood pressure levels had a high correlation at 0.93, and most variables correlated moderately with the dependent variable of blood pressure control. The regression model (R = 0.698) using the dependent variable (blood pressure control) as the outcome strongly correlated with the independent variables, explaining almost 49% of the variance in hypertension control. It was observed that blood pressure control was significantly predicted by adherence to antihypertensive medication, proper diet, exercise, and stress reduction among the participants.Conclusion: The study emphasizes the significance of lifestyle changes for effective hypertension control, specifically adherence to antihypertensive medication, diet, exercise, and stress management. Hypertensive patients in Sudan experienced much better blood pressure control and a decreased risk of cardiovascular problems after changing their lifestyle.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 5","pages":"38-45"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between simple electrocardiographic parameter and paroxysmal atrial fibrillation. 单纯心电图参数与阵发性心房颤动的关系。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.41690.2900

Mohammad Assadian Rad, Hanie Shadrou, Sajad Kazemalilou, Habib Eslami Kenarsari, Mahboobeh Gholipour

{"title":"Relationship between simple electrocardiographic parameter and paroxysmal atrial fibrillation.","authors":"Mohammad Assadian Rad, Hanie Shadrou, Sajad Kazemalilou, Habib Eslami Kenarsari, Mahboobeh Gholipour","doi":"10.48305/arya.2024.41690.2900","DOIUrl":"10.48305/arya.2024.41690.2900","url":null,"abstract":"Background: Atrial fibrillation (AF) is a prevalent arrhythmia, and predicting its occurrence plays a crucial role in reducing its complications. This study aimed to investigate the relation between simple P wave parameters and paroxysmal AF (pAF).Methods: In this case-control study, demographic and laboratory data were gathered by a checklist. P wave parameters were measured in electrocardiography (ECG). The relationship between these parameters and AF in groups was analyzed.Results: Eighty individuals were included (40 patients with pAF (57.5% female, mean age = 64.9 ± 2.04) and 40 individuals without AF (57.5% female, mean age = 60.3 ± 2.01)). The P wave peak time (PWPT) in leads D2 (p = 0.003) and V1 (p = 0.001) were longer in the case group. In addition, the prolongation of the PR interval (PR) in lead D2, P wave duration (PWD) in lead D2, and P terminal force (PTF) in V1 were associated with an increase in the occurrence of pAF. Adjusted regression analysis showed that two variables, PWPT in V1 (OR, 95% CI: 1.04 (1.01-1.07), p = 0.005) and PWD in D2 (OR, 95% CI: 1.03 (1.00-1.05), p = 0.018), were predictors for AF.Conclusion: Our results underscore the potential utility of simple ECG parameters, especially PWD in lead D2 and PWPT in V1, in predicting and assessing the risk of pAF. These findings provide valuable insights for clinical practice and risk stratification in patients without structural cardiac disease. Additionally, these findings may potentially contribute to the prevention of complications and injuries associated with pAF.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 5","pages":"6-14"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Importance of ECG findings in COVID-19 patients: Predictor of in-hospital prognosis. COVID-19 患者心电图结果的重要性：院内预后的预测因素。

IF 0.8

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2023.41600.2887

Mahsa Behnemoon, Mojhdeh Mehrno, Vahid Alinejad

{"title":"Importance of ECG findings in COVID-19 patients: Predictor of in-hospital prognosis.","authors":"Mahsa Behnemoon, Mojhdeh Mehrno, Vahid Alinejad","doi":"10.48305/arya.2023.41600.2887","DOIUrl":"10.48305/arya.2023.41600.2887","url":null,"abstract":"Background: Cardiac injury in COVID-19 patients confers a worse prognosis. The interpretation of electrocardiography can be beneficial in the early diagnosis of probable cardiac involvement. After adjusting for other variables, we sought to determine if the initial ECG on admission could add additional prognostic value.Methods: In this single-center cross-sectional study, 1165 patients with a positive COVID-19 PCR between Feb 2020 and Nov 2021 were enrolled in our study. Patients were grouped according to their admitted units, and survivors to hospital discharge or non-survivors. Predictors of ICU admission and in-hospital mortality were determined using univariate analysis and a logistic regression model.Results: The mean age was 55.6 ± 16.2 years and 52% were male. Out of 1165 patients, 149 deaths (12.8%) were recorded during hospitalization. Sinus tachycardia was the most common dysrhythmia, followed by premature atrial and ventricular beats, sinus bradycardia, and atrial fibrillation (28.6%, 5.6%, 3.9%, and 2.1%, respectively). Age (p<0.001), sex (p=0.006), history of diabetes mellitus (p=0.002), hypertension (p=0.018), ischemic heart disease (p=0.004), and cancer (p<0.001) were more frequent among non-survivors. Among ECG findings, tachycardia, low voltage QRS, ST-T changes, and dysrhythmia were related to an increased mortality risk. However, in regression analysis, only sex (OR 1.89, 95% CI 1.2 to 2.9, p=0.004), age (OR 1.03, 95% CI 1.02 to 1.05, p<0.001), and initial tachycardia (OR 1.02, 95% CI 1.01 to 1.03, p<0.001) were independent predictors of in-hospital mortality.Conclusion: Our data suggest that initial electrocardiographic findings could be helpful in distinguishing patients with an increased risk for ICU admission or in-hospital death.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 1","pages":"41-50"},"PeriodicalIF":0.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11331551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142009663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and efficacy of mobile application to improve medication adherence for persons with cardiac disease. 提高心脏病患者服药依从性的移动应用程序的开发和疗效。

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42169.2924

Raziyeh Ghafouri, Roxana Karbaschi, AliReza Mashhadi Hosein, Shakila Sharifian

{"title":"Development and efficacy of mobile application to improve medication adherence for persons with cardiac disease.","authors":"Raziyeh Ghafouri, Roxana Karbaschi, AliReza Mashhadi Hosein, Shakila Sharifian","doi":"10.48305/arya.2024.42169.2924","DOIUrl":"10.48305/arya.2024.42169.2924","url":null,"abstract":"Background: Patients with cardiovascular disease need to adhere to their treatment and care recommendations to prevent the progression of their condition and improve their quality of life. In this regard, this study was conducted to develop a mobile application and test its effectiveness in improving medication adherence among persons with cardiac disease.Methods: The study was conducted in two stages. The first stage involved the preparation of the \"Mobile Application for Persons with Cardiac Disease\" using the cascade model. In the second stage, 121 patients who were hospitalized in the cardiac intensive care unit of Ayatollah Taleghani Medical Education Center of Tehran from March to August 2023 were enrolled. The participants were randomly assigned to either the control group (63 people) or the intervention group (58 people). The study collected data using a medication adherence questionnaire on the 7th, 14th, and 21st day after discharge and compared the results with the control group. The data were analyzed using SPSS 20.Results: The average age of the control group was 56.75 ± 11.38 years, and the average age of the intervention group was 57.03 ± 11.55 years. The comparison of the average medication adherence with independent t-tests showed a significant difference between the intervention and control groups on the 7th, 14th, and 21st day after discharge (P<0.01). The results of the repeated measures test in each group also showed that the difference between the groups increased over time (P<0.001).Conclusion: The results of the study showed that the mobile application is effective in improving medication adherence among heart patients.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 3","pages":"28-36"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical performance and safety of the Vector® percutaneous transluminal coronary angioplasty balloon catheter: A single-arm, multicenter, retrospective post-marketing clinical study. Vector®经皮冠状动脉腔内成形术球囊导管的临床性能和安全性：单臂、多中心、回顾性上市后临床研究

IF 0.5

ARYA Atherosclerosis Pub Date : 2024-01-01 DOI: 10.48305/arya.2024.42702.2971

Preeti Vani, Arvind Patel, Kumar Abhishek, Kailash Goyal

{"title":"Clinical performance and safety of the Vector® percutaneous transluminal coronary angioplasty balloon catheter: A single-arm, multicenter, retrospective post-marketing clinical study.","authors":"Preeti Vani, Arvind Patel, Kumar Abhishek, Kailash Goyal","doi":"10.48305/arya.2024.42702.2971","DOIUrl":"10.48305/arya.2024.42702.2971","url":null,"abstract":"Background: The present post-marketing clinical study was conducted over a 12-month follow-up period to monitor the clinical outcomes of patients treated with the Vector® Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter for the dilatation of coronary lesions. The semi-compliant balloon improves balloon-to-vessel wall apposition and minimizes balloon slippage during PTCA, which could reduce complications and improve clinical outcomes. This investigation aimed to assess the safety and effectiveness of the Vector® PTCA Balloon Catheter in real-world settings.Methods: A retrospective study was conducted to investigate the safety and efficacy of the Vector® PTCA Balloon Catheter in 125 patients who underwent pre-dilatation and post-dilatation. The primary outcome of the study was major adverse cardiac events (MACE), a composite endpoint encompassing target-lesion revascularization (TLR), cardiac death, and myocardial infarction (MI).Results: The Vector® PTCA Balloon Catheter has shown promising results in a small group of patients undergoing dilatation of normal and intricate coronary artery lesions, reflecting a 100% procedural success rate. The successful delivery to the target lesion, deployment, and subsequent retrieval of the device during the index procedure led to a 100% device success rate without any technical issues. A total of 3.2% (4) patients experienced MACE during the 12-month follow-up, with 1.6% (2) MI, 1.6% (2) TLR, and no cardiovascular deaths..Conclusion: This study demonstrated the favorable safety and reliability of the Vector® PTCA Balloon Catheter in patients with angina, MI, and a history of coronary artery disease in a real-world setting.","PeriodicalId":46477,"journal":{"name":"ARYA Atherosclerosis","volume":"20 6","pages":"17-26"},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0