{"title":"Postoperative Complications Following Open Reduction and Internal Fixation of Mandibular Condylar Fractures Using the High Perimandibular Approach: A Multicenter Retrospective Study.","authors":"Noriko Sakata, Masako Fujioka-Kobayashi, Yuhei Matsuda, Reon Morioka, Erina Toda, Shinji Ishizuka, Michitaka Somoto, Rie Sonoyama-Osako, Hiroto Tatsumi, Takahiro Kanno","doi":"10.3390/cmtr18040047","DOIUrl":"10.3390/cmtr18040047","url":null,"abstract":"<p><strong>Background: </strong>The high perimandibular approach (HPA) is a feasible surgical technique for open reduction and internal fixation (OR-IF) of mandibular condylar fractures, offering reduced complication rates. In this study, we retrospectively evaluated the treatment outcomes and complications associated with HPA use.</p><p><strong>Patients and methods: </strong>Patients who underwent OR-IF for mandibular condylar fractures using the HPA at three hospitals in Shimane between June 2019 and March 2024 were included. Data collected included the mechanism of injury, AO classification of the fracture site, fracture type and mode, surgical duration, mouth-opening range at 6 months post-operatively, and peri- and post-operative complications.</p><p><strong>Results: </strong>A total of 42 patients (46 condylar fractures; 18 males and 24 females; mean age, 63.0 years) were included. The fracture pattern included dislocations in 18 cases (42.8%). The mean surgical duration was 75.0 min. Post-operative trismus occurred in 16 patients (38.1%) at 6 months. Longer surgical duration and dislocated fractures were significantly associated with post-operative trismus (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>The HPA is safe and effective for managing mandibular condylar fractures. However, post-operative trismus may be influenced by longer surgical duration and fracture types, warranting further investigation and potential post-surgical management.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 4","pages":"47"},"PeriodicalIF":0.4,"publicationDate":"2025-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12641782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145606941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ming Yan Cheung, Ankit Nayak, Xing-Na Yu, Kar Yan Li, Yu-Xiong Su, Jingya Jane Pu
{"title":"Development of an Automatic Computer Program to Determine the Optimal Dental Implant Size and Position for Fibula Free Flap Surgery.","authors":"Ming Yan Cheung, Ankit Nayak, Xing-Na Yu, Kar Yan Li, Yu-Xiong Su, Jingya Jane Pu","doi":"10.3390/cmtr18040046","DOIUrl":"10.3390/cmtr18040046","url":null,"abstract":"<p><p>Computer-assisted surgery (CAS) and virtual surgical planning (VSP) have transformed jaw reconstruction, allowing immediate insertion of dental implants during surgery for better rehabilitation of occlusal function. However, traditional planning for optimal location and angulation of dental implants and fibula relies on experience and can be time-consuming. This study aimed to propose a function-driven workflow and develop an automatic computer program for optimal positioning of simultaneous dental implants and fibula segments. A customized computer program was developed using MATLAB. Computed tomography (CT) of the lower limbs of ninety-one Southern Chinese individuals was retrieved and cross-sections of three-dimensional (3D) fibula models were comprehensively investigated for implant installation. Our research proves that the accuracy of the program in identifying the anatomical orientation of the fibula was 92%. The ideal location, angulation and length of implant could be automatically generated based on any selected implant diameter, with a surgical feasibility of 94%. To the best of our knowledge, this is the first study to develop and validate a customized automatic computer program for osseointegrated implant design in fibula flap surgery. This program can be incorporated into the current workflow of CAS to further the development of reliable and efficient surgical planning for function-driven jaw reconstruction.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 4","pages":"46"},"PeriodicalIF":0.4,"publicationDate":"2025-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12641722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145606916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimizing Maxillomandibular Position in Orthognathic Surgery: Introducing the T Concept in Treatment Planning.","authors":"Abdulmalik Alyahya, Saud Bin Jasser","doi":"10.3390/cmtr18040045","DOIUrl":"10.3390/cmtr18040045","url":null,"abstract":"<p><p><b>Background</b>: Orthognathic surgery aims to align the jaws with the facial skeleton and correct dental occlusion. This paper introduces the concept of planning the maxillomandibular complex (MMC) as a whole, utilizing a t-forming set of landmarks: the maxillary central incisor, the chin, and the occlusal plane. <b>Methods</b>: The background, hypothesis, and rationale of the new T concept are explained. A case of a 28-year-old male with skeletal class III malocclusion and an open bite was used to illustrate the application of the T concept in step-by-step surgical planning. The planning encompasses four phases: Phase One involves correcting frontal deformity and various asymmetries, Phase Two involves correcting chin anterior-posterior deformity, Phase Three involves correcting anterior-posterior and vertical MMC position, and Phase Four involves correcting MMC rotation. <b>Results</b>: The T concept provided a structured approach to plan MMC as a whole and integrate all structures into harmony. <b>Conclusions</b>: The T concept provides a logical approach to MMC positioning in orthognathic surgery, addressing functional and aesthetic concerns. It acts as a checkpoint to verify MMC position, helping surgeons achieve better results and avoid compensatory procedures.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 4","pages":"45"},"PeriodicalIF":0.4,"publicationDate":"2025-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12641982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145606889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laurence Verstraete, Paulien Schillemans, Jan Meeus, Philippe Vuylsteke, Robin Willaert
{"title":"Minimally Invasive Endoscopic Transorbital Approach for Frontal Sinus Fractures: A Comparative Study.","authors":"Laurence Verstraete, Paulien Schillemans, Jan Meeus, Philippe Vuylsteke, Robin Willaert","doi":"10.3390/cmtr18030041","DOIUrl":"10.3390/cmtr18030041","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the use of the endoscopic transorbital approach for reducing frontal sinus fractures and compare its outcomes with the traditional bicoronal approach.</p><p><strong>Methods: </strong>A retrospective comparative analysis of case studies including all patients with frontal sinus fractures treated at our institution between January 2013 and December 2023 was conducted. Patients were categorized based on treatment approach (through traumatic laceration, bicoronal, or endoscopic transorbital). For the comparative analysis, cases with associated maxillofacial fractures or cerebrospinal fluid (CSF) leakage were excluded.</p><p><strong>Results: </strong>Out of 133 patients, 35 underwent surgery, with 6 patients treated using the endoscopic transorbital approach. This group of patients treated with the transorbital endoscopic approach demonstrated significantly shorter operative times compared to the bicoronal approach (mean 102 vs. 168 min, <i>p</i> = 0.021). They also had only minor complications, including temporary hypoesthesia and one transient ptosis. One patient had a minimal residual defect. The technique has been concluded to require endoscopic expertise.</p><p><strong>Conclusions: </strong>The endoscopic transorbital approach is a safe, minimally invasive alternative to the bicoronal approach for selected anterior wall frontal sinus fractures. Proper patient selection and surgical experience are essential to achieving favorable outcomes. Studies with longer follow-up are required to assess potential late complications, such as the development of mucoceles.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 3","pages":"41"},"PeriodicalIF":0.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12468538/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bruno Nifossi Prado, Lucas Cavalieri Pereira, Bianca Pulino, Raphael Capelli Guerra
{"title":"Integrative Innovation in Genioplasty: Advanced 3D Plate Design: Promoting Stability, Aesthetics, and Harmony Excellence.","authors":"Bruno Nifossi Prado, Lucas Cavalieri Pereira, Bianca Pulino, Raphael Capelli Guerra","doi":"10.3390/cmtr18030042","DOIUrl":"10.3390/cmtr18030042","url":null,"abstract":"<p><strong>Background: </strong>Genioplasty is a well-established surgical technique for reshaping the chin and enhancing facial harmony. However, conventional fixation methods may present biomechanical and aesthetic limitations.</p><p><strong>Objective: </strong>This study introduces and evaluates a novel Anatomical Chin Plate (ACP), designed to enhance mechanical performance and facial aesthetics compared to the conventional chin plate (CP).</p><p><strong>Methods: </strong>A three-dimensional finite element analysis (FEA) was conducted to compare stress distribution in ACP and CP models under a standardized oblique load of 60 N, simulating muscle forces from the mentalis and digastric muscles. Plates were modeled using Blender and analyzed using ANSYS software 2025 r2. Mechanical behavior was assessed based on von Mises stress, concentration sites, and potential for plastic deformation or fatigue failure.</p><p><strong>Results: </strong>The ACP demonstrated a significantly lower maximum von Mises stress (77.19 MPa) compared to the CP (398.48 MPa). Stress distribution in the ACP was homogeneous, particularly around the lateral fixation holes, while the CP exhibited concentrated stress between central screw holes. These findings indicate that the anatomical geometry of the ACP enhances load dispersion, reduces critical stress concentrations, and minimizes fatigue risk.</p><p><strong>Conclusions: </strong>The ACP design offers superior biomechanical behavior and improved aesthetic potential for genioplasty procedures. Its optimized shape allows for better integration with facial anatomy while providing stable fixation. Further studies are recommended to validate in vitro performance and explore clinical applicability in advanced genioplasty and complex osteotomies.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 3","pages":"42"},"PeriodicalIF":0.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12469031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reinier S A Ten Brink, Bram J Merema, Marith E den Otter, Willemina A van Veldhuizen, Max J H Witjes, Joep Kraeima
{"title":"Towards MRI-Only Mandibular Resection Planning: CT-like Bone Segmentation from Routine T1 MRI Images Using Deep Learning.","authors":"Reinier S A Ten Brink, Bram J Merema, Marith E den Otter, Willemina A van Veldhuizen, Max J H Witjes, Joep Kraeima","doi":"10.3390/cmtr18030040","DOIUrl":"10.3390/cmtr18030040","url":null,"abstract":"<p><p>We present a deep learning-based approach for accurate bone segmentation directly from routine T1-weighted MRI scans, with the goal of enabling MRI-only virtual surgical planning in head and neck oncology. Current workflows rely on CT for bone modeling and MRI for tumor delineation, introducing challenges related to image registration, radiation exposure, and resource use. To address this, we trained a deep neural network using CT-based segmentations of the mandible, cranium, and inferior alveolar nerve as ground truth. A dataset of 100 patients with paired CT and MRI scans was collected. MRI scans were resampled to the voxel size of CT, and corresponding CT segmentations were rigidly aligned to MRI. The model was trained on 80 cases and evaluated on 20 cases using Dice similarity coefficient, Intersection over Union (IoU), precision, and recall. The network achieved a mean Dice of 0.86 (SD ± 0.03), IoU of 0.76 (SD ± 0.05), and both precision and recall of 0.86 (SD ± 0.05). Surface deviation analysis between CT- and MRI-derived bone models showed a median deviation of 0.21 mm (IQR 0.05) for the mandible and 0.30 mm (IQR 0.05) for the cranium. These results demonstrate that accurate CT-like bone models can be derived from standard MRI, supporting the feasibility of MRI-only surgical planning.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 3","pages":"40"},"PeriodicalIF":0.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flávio Fidêncio de Lima, Tayná Mendes Inácio De Carvalho, Bianca Pulino, Camila Cerantula, Mônica Grazieli Correa, Raphael Capelli Guerra
{"title":"Evaluation of the Upper Airway in Class II Patients Undergoing Maxillary Setback and Counterclockwise Rotation in Orthognatic Surgery.","authors":"Flávio Fidêncio de Lima, Tayná Mendes Inácio De Carvalho, Bianca Pulino, Camila Cerantula, Mônica Grazieli Correa, Raphael Capelli Guerra","doi":"10.3390/cmtr18030039","DOIUrl":"10.3390/cmtr18030039","url":null,"abstract":"<p><strong>Introduction: </strong>Maxillary setback in orthognathic surgery has been extensively discussed regarding its effects on bone healing and facial soft tissue profile; however, its impact on upper airway volume remains unclear.</p><p><strong>Objective: </strong>We evaluate the influence of maxillary setback combined with counterclockwise (CCW) rotation of the occlusal plane on upper airway dimensions.</p><p><strong>Methods: </strong>A retrospective observational case series was conducted with eight patients diagnosed with Class II malocclusion who underwent orthognathic surgery involving maxillary setback and CCW mandibular rotation. All procedures were performed by the same surgeon. Preoperative (T1) and 6-month postoperative (T2) facial CT scans were analyzed using Dolphin Imaging software11.7 to measure airway volume (VOL), surface area (SA), and linear distances D1, D2 and D3. Statistical analysis was performed using the Wilcoxon test with a 5% significance level.</p><p><strong>Results: </strong>Significant skeletal changes were observed, including 10.2 mm of mandibular advancement, 5.2 mm of hyoid advancement, and 4.1° of CCW rotation. Although increases in airway volume and surface area were noted, they did not reach statistical significance (<i>p</i> = 0.327 and <i>p</i> = 0.050, respectively), but suggesting a favorable trend toward airway adaptation.</p><p><strong>Conclusions: </strong>Maxillary setback combined with CCW rotation appears to safely correct Class II skeletal deformities without compromising upper airway space. These preliminary findings highlight the technique's potential for both functional and aesthetic outcomes, warranting further long-term studies.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 3","pages":"39"},"PeriodicalIF":1.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Jaw in a Day: How to Perform Your First Case-Our Workflow.","authors":"Camilo Mosquera, Hisham Marwan","doi":"10.3390/cmtr18030038","DOIUrl":"10.3390/cmtr18030038","url":null,"abstract":"<p><p>Jaw in a Day (JIAD) reconstruction provides immediate restoration of mandibular form and function through a single-stage procedure that integrates fibula free flap reconstruction, virtual surgical planning (VSP), immediate dental implant placement, and delivery of a prefabricated prosthesis. Although the technique provides significant benefits in reducing rehabilitation time and improving patient outcomes, its adoption has been limited due to perceived technical complexity and unfamiliarity with dental workflow. This manuscript provides a detailed, step-by-step protocol to guide surgeons through their first JIAD case, from patient selection and data acquisition to VSP execution, intraoperative coordination, and implant positioning. Emphasis is placed on accurate osteotomy design, implant placement using guided protocols, fabrication of patient-specific hardware, and precise prosthesis pickup techniques. This guide also addresses essential OR team preparation and sterile handling of non-sterile components. By breaking down the process into actionable stages and highlighting common pitfalls and technical tips, this resource aims to lower the barrier for early adopters and enhance the success of initial JIAD cases.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 3","pages":"38"},"PeriodicalIF":0.4,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Therapeutic Alcohol Administration on Perioperative Quality of Life (QoL) and Fracture Healing in Patients with Alcohol Use Disorder Undergoing Surgery for Maxillofacial Trauma-A Randomized Pilot Trial.","authors":"Elavenil Panneerselvam, Rajkumar Krishnan, Jaikumar Velayudham","doi":"10.3390/cmtr18030037","DOIUrl":"10.3390/cmtr18030037","url":null,"abstract":"<p><p>Alcohol Use Disorder (AUD) is common among patients with maxillofacial trauma. Conventional perioperative care recommends complete abstinence. However, abrupt cessation can lead to Alcohol Withdrawal Syndrome (AWS), negatively impacting psychological well-being and compliance. This randomized controlled pilot study evaluated the effectiveness of Monitored Therapeutic Alcohol Administration (MTAA) in reducing perioperative stress and enhancing quality of life without impairing fracture healing. Twenty-four adult male patients with AUD and isolated facial fractures requiring surgery were enrolled. They were assigned to either an intervention group (n = 12) receiving MTAA-oral alcohol at 0.5 g/kg/day for two weeks-or a control group (n = 12) undergoing complete abstinence. Outcomes were assessed over six weeks, including stress (Zung Self-Rating Depression Scale), quality of life (Oral Health Impact Profile-14), soft tissue healing (Landry's Index), and hard tissue healing (Moed's Scale, serum osteocalcin). The MTAA group showed significantly reduced stress and improved quality of life (<i>p</i> < 0.001). Healing outcomes were comparable between groups, with no significant differences in soft tissue indices, osteocalcin levels, or radiographic scores. MTAA appears to be a safe and effective strategy to manage AWS-related distress and improve postoperative recovery, offering a practical alternative to strict abstinence in the surgical management of patients with AUD.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 3","pages":"37"},"PeriodicalIF":1.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose Carlos Román Padilla, Luis Ortiz Peces, Pol Alavedra Martínez, Jose Luis Cebrián Carretero
{"title":"Is Simple Reimplantation a Viable Option in Pediculated Auricular Avulsions? A Systematic Review of the Literature.","authors":"Jose Carlos Román Padilla, Luis Ortiz Peces, Pol Alavedra Martínez, Jose Luis Cebrián Carretero","doi":"10.3390/cmtr18030036","DOIUrl":"10.3390/cmtr18030036","url":null,"abstract":"<p><p>Auricular avulsion injuries are rare, and microvascular reimplantation is considered the preferred treatment according to current literature. However, when a small skin pedicle is preserved, non-microvascular reattachment techniques may offer comparable outcomes. This systematic review aims to assess whether these techniques could represent a viable alternative. We analyzed 32 cases of pedicled auricular avulsion reported in 16 articles, focusing on patient demographics, injury mechanisms, pedicle characteristics, venous congestion, and postoperative management. Venous congestion occurred in 11 patients, with a significantly higher risk in narrower pedicles (mean width 9.82 mm; 95% CI: 4.75-14.89; <i>p</i> = 0.025). Prophylactic heparin significantly reduced this risk (<i>p</i> = 0.007). Other interventions-leech therapy and hyperbaric oxygen-lacked sufficient data for firm conclusions. Most cases achieved graft survival; necrosis occurred in some, and only two patients required additional surgery. Non-microvascular techniques appear to be a viable alternative to microvascular reimplantation, with similar results and potentially fewer complications. Venous congestion remains the main challenge, requiring active management and hospitalization for monitoring. Limited case series and publication bias still hinder the development of standardized guidelines.</p>","PeriodicalId":46447,"journal":{"name":"Craniomaxillofacial Trauma & Reconstruction","volume":"18 3","pages":"36"},"PeriodicalIF":0.4,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12452382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}