{"title":"Clinical Advances in Neuromuscular Diseases: Neurometabolic Disorders","authors":"C. Angelini, D. Tavian","doi":"10.3390/muscles2030020","DOIUrl":"https://doi.org/10.3390/muscles2030020","url":null,"abstract":"Metabolic myopathies are characterized by the dysfunction of several metabolic pathways that results in a deficiency of fuels required to generate energy for muscle contractions [...]","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"189 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73689810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Lee, L. Appiah-Kubi, Simon J. Vogrin, J. Zanker, Joanna Mitropoulos
{"title":"Current Cut Points of Three Falls Risk Assessment Tools Are Inferior to Calculated Cut Points in Geriatric Evaluation and Management Units","authors":"V. Lee, L. Appiah-Kubi, Simon J. Vogrin, J. Zanker, Joanna Mitropoulos","doi":"10.3390/muscles2030019","DOIUrl":"https://doi.org/10.3390/muscles2030019","url":null,"abstract":"Background: Falls risk assessment tools are used in hospital inpatient settings to identify patients at increased risk of falls to guide and target interventions for fall prevention. In 2022, Western Health, Melbourne, Australia, introduced a new falls risk assessment tool, the Western Health St. Thomas’ Risk Assessment Tool (WH-STRATIFY), which adapted The Northern Hospital’s risk tool (TNH-STRATIFY) by adding non-English speaking background and falls-risk medication domains to reflect patient demographics. WH-STRATIFY replaced Peninsula Health Risk Screening Tool (PH-FRAT) previously in use at Western Health. This study compared the predictive accuracy of the three falls risk assessment tools in an older inpatient high-risk population. Aims: To determine the predictive accuracy of three falls risk assessment tools (PH-FRAT, TNH-STRATIFY, and WH-STRATIFY) on admission to Geriatric Evaluation Management (GEM) units (subacute inpatient wards where the most frail and older patients rehabilitate under a multi-disciplinary team). Method: A retrospective observational study was conducted on four GEM units. Data was collected on 54 consecutive patients who fell during admission and 62 randomly sampled patients who did not fall between December 2020 and June 2021. Participants were scored against three falls risk assessment tools. The event rate Youden (Youden IndexER) indices were calculated and compared using default and optimal cut points to determine which tool was most accurate for predicting falls. Results: Overall, all tools had low predictive accuracy for falls. Using default cut points to compare falls assessment tools, TNH-STRATIFY had the highest predictive accuracy (Youden IndexER = 0.20, 95% confidence interval CI = 0.07, 0.34). The PH-FRAT (Youden IndexER = 0.01 and 95% CI = −0.04, 0.05) and WH-STRATIFY (Youden IndexER = 0.00 and 95% CI = −0.04, 0.03) were statistically equivalent and not predictive of falls compared to TNH-STRATIFY. When calculated optimal cut points were applied, predictive accuracy improved for PH-FRAT (Cut point 17, Youden IndexER = 0.14 and 95% CI = 0.01, 0.29) and WH-STRATIFY (Cut point 7, Youden IndexER = 0.18 and 95% CI = 0.00, 0.35). Conclusions: TNH-STRATIFY had the highest predictive accuracy for falls. The predictive accuracy of WH-STRATIFY improved and was significant when the calculated optimal cut point was applied. The optimal cut points of falls risk assessment tools should be determined and validated in different clinical settings to optimise local predictive accuracy, enabling targeted fall risk mitigation strategies and resource allocation.","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85916268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiroto Honda, Hiromi Fukutomi, M. Igaki, Shinichiro Tanaka, T. Takaishi, T. Hayashi
{"title":"The Chronic Effect of Stair Climbing–Descending Exercises after Meals on Glycemic Control in Individuals with Type 2 Diabetes: A Randomized Controlled Trial","authors":"Hiroto Honda, Hiromi Fukutomi, M. Igaki, Shinichiro Tanaka, T. Takaishi, T. Hayashi","doi":"10.3390/muscles2020018","DOIUrl":"https://doi.org/10.3390/muscles2020018","url":null,"abstract":"This study aimed to examine the chronic effect of a stair climbing–descending exercise (ST-EX) program on glycemic control in individuals with type 2 diabetes (T2D). Sixteen T2D participants were randomly divided into two groups and followed up over 12 weeks: they either performed regular ST-EX after meals at home (n = 8) or maintained their daily routine (CON; no training) (n = 8). The participants in the ST-EX group were instructed to perform a minimum of 12 sessions/week of ST-EX for more than three days/week. One session of ST-EX consisted of two repetitions of 3 min bouts of climbing to the second floor, followed by walking down to the first floor. Fourteen participants completed the study (seven for each group). The decrease in glycoalbumin levels was significantly greater in the ST-EX group (mean value: −1.0%) than in the CON group (+0.4%). Moreover, the knee extension force increased greatly in the ST-EX group (+0.2 Nm/kg) compared with that in the CON group (−0.1 Nm/kg), with no significant change in the skeletal muscle mass. Performing regular ST-EX after meals may be an effective strategy to improve glycemic control and lower-extremity muscle strength in individuals with T2D.","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83836139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gaven A. Barker, Alyssa L. Parten, David A. Lara, Kensey E. Hannon, M. McAllister, Hunter S. Waldman
{"title":"Astaxanthin Supplementation Reduces Subjective Markers of Muscle Soreness following Eccentric Exercise in Resistance-Trained Men","authors":"Gaven A. Barker, Alyssa L. Parten, David A. Lara, Kensey E. Hannon, M. McAllister, Hunter S. Waldman","doi":"10.3390/muscles2020017","DOIUrl":"https://doi.org/10.3390/muscles2020017","url":null,"abstract":"Strenuous exercise involving eccentric muscle actions induces skeletal muscle damage resulting in delayed onset muscle soreness (DOMS). Antioxidant supplementation, such as astaxanthin (AX), may alleviate muscle injury following intense exercise. The purpose of this study was to investigate the effect of a four-week course of AX supplementation at 12 mg/day−1 on subjective markers of DOMS, recovery, and performance after a bout of muscle damaging eccentric exercise. Nineteen resistance-trained men (mean ± SD: age, 22.6 ± 2.2 y) completed a between-group design with a four-week supplementation period of 12 mg/day−1 of either AX or a placebo. Subjects completed four trials, with trials One and Three designed to induce muscle damage, consisting of a one repetition maximum test (1RM) for leg-press, followed by five sets of ten repetitions at 65% of 1RM. Trials Two and Four were performance trials, conducted 48 h later and consisting of repetitions to failure at 65%, 70%, and 75% of 1RM. Subjective markers of DOMS and recovery were collected at multiple timepoints post-trial for trials One and Three. Although performance was not affected (p > 0.05), AX supplementation significantly decreased subjective markers of DOMS (p = 0.01) compared to the placebo. The results demonstrated that AX may enhance recovery by reducing DOMS without detriment to performance in resistance-trained men.","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"10 10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82876359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Saeedzadeh, D.S. Khoshkrodi, khosro khademi-kalantari, A. Akbarzadeh Baghban, M. Khalkhali Zavieh
{"title":"Neck Muscles Sense of Force in Healthy Individuals and Subjects with Trigger Points of the Upper Trapezius Muscle","authors":"M. Saeedzadeh, D.S. Khoshkrodi, khosro khademi-kalantari, A. Akbarzadeh Baghban, M. Khalkhali Zavieh","doi":"10.32098/mltj.02.2023.15","DOIUrl":"https://doi.org/10.32098/mltj.02.2023.15","url":null,"abstract":"","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73316047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Saseedharan, R. R. Chada, S. Rambhad, A. Bhurke, E. Mathew, K. Paradkar
{"title":"Muscle Mass Loss in Mechanically Ventilated Critically Ill Patients in Intensive Care Unit","authors":"S. Saseedharan, R. R. Chada, S. Rambhad, A. Bhurke, E. Mathew, K. Paradkar","doi":"10.32098/mltj.02.2023.13","DOIUrl":"https://doi.org/10.32098/mltj.02.2023.13","url":null,"abstract":"","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77754688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Almuhaish, I. AlFawaz, T. Hegazi, S. A. Al-Mousa, S. Alsubaie, A. Alkhaldi, M. Almutairi, T. H. Alshammari, H. F. Alhowaish, M. Alzahrani
{"title":"Anatomical Variation of the Sciatic Nerve in Relation to the Piriformis Muscle: An MRI Study","authors":"M. Almuhaish, I. AlFawaz, T. Hegazi, S. A. Al-Mousa, S. Alsubaie, A. Alkhaldi, M. Almutairi, T. H. Alshammari, H. F. Alhowaish, M. Alzahrani","doi":"10.32098/mltj.02.2023.05","DOIUrl":"https://doi.org/10.32098/mltj.02.2023.05","url":null,"abstract":"","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82271531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calcium is Involved in Necroptosis Through the Expression of Phospho-MLKL in Skeletal Muscle Cell in Mice","authors":"R. Yashiro, Y. Matsuzaka","doi":"10.32098/mltj.02.2023.03","DOIUrl":"https://doi.org/10.32098/mltj.02.2023.03","url":null,"abstract":"","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80673747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Hegde, Shashwat Agrawal, B. S. Rao, P. Mane, Chethan B. Shetty, Vikrant Khanna, Samarth Thakkar, P. Divakar, Ankita Nigam
{"title":"Peroneus Longus Tendon Autograft for Primary Arthroscopic Reconstruction of the Anterior Cruciate Ligament","authors":"A. Hegde, Shashwat Agrawal, B. S. Rao, P. Mane, Chethan B. Shetty, Vikrant Khanna, Samarth Thakkar, P. Divakar, Ankita Nigam","doi":"10.32098/mltj.02.2023.08","DOIUrl":"https://doi.org/10.32098/mltj.02.2023.08","url":null,"abstract":"Purpose. Peroneus longus tendon graft is not a popular first choice for ACL reconstruction. However, newer literature has shown good outcomes with its use. This study compares functional outcome and donor site morbidity of peroneus longus with hamstring tendon autograft to assess if it can be considered as one of the first choices for ACLR. Methods. This prospective cohort study involves 54 patients who underwent arthroscopic single-bundle ACLR. 27 patients each were operated on with hamstring and peroneus longus autografts. At 2 years follow-up, functional outcome was compared between groups using International Knee Documentation Committee (IKDC), Modified Cincinnati, and Tegner-Lysholm scores. Donor site morbidity in the peroneus longus group was assessed using Foot and Ankle Disability Index (FADI) and The American Orthopaedic Foot and Ankle Society (AOFAS) scores. Results. At 2 years follow-up, there was no statistically significant difference in the mean IKDC (77.26 vs 80.78), Modified Cincinnati (84.41 vs 89.07), and Tegner-Ly-sholm scores (85.19 vs 88.78) between the hamstring and peroneus groups respectively. Mean FADI and AOFAS scores at 2 years follow up were 96.11 and 91.67 respectively in the peroneus group suggesting no significant donor site morbidity as compared to preoperative scores. Conclusions. Peroneus longus performs similar to hamstring grafts and can be considered as one of the first choices for arthroscopic ACL reconstruction.","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85635125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Saremi, B. Heidari, A. Sharifi, E. Khanlarzadeh
{"title":"Arthroscopic Biceps Tenodesis: Midterm Clinical Results of a New Anchor Suture Technique in Patients with Single-Row Rotator Cuff Repair","authors":"H. Saremi, B. Heidari, A. Sharifi, E. Khanlarzadeh","doi":"10.32098/mltj.02.2023.09","DOIUrl":"https://doi.org/10.32098/mltj.02.2023.09","url":null,"abstract":"","PeriodicalId":46318,"journal":{"name":"MLTJ-Muscles Ligaments and Tendons Journal","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85725963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}