Journal of Infusion Nursing最新文献_第2页

Article Replacement Statement: Implementing a 4% EDTA Central Catheter Locking Solution as a Quality Improvement Project in a Large Canadian Hospital. 文章替代声明：在加拿大一家大型医院实施4% EDTA中心导管锁定方案作为质量改进项目。

IF 1.2

Journal of Infusion Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1097/NAN.0000000000000636

引用次数: 0

Peripheral Vasopressor Administration in Adults With Sepsis: A Retrospective Study of Guideline Adherence and Complications. 成人脓毒症患者外周血管加压药的应用：指南依从性和并发症的回顾性研究。

IF 1.2

Journal of Infusion Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1097/NAN.0000000000000626

Spencer Mann, Susan H Weaver, Weddy Balmaceda, Mary Bobek, Melanie Cardona, Joan Harvey, Sharon Jones, Miriam McNicholas, Mani Paliwal, Deborah Prinzo, Marlene M Steinheiser

{"title":"Peripheral Vasopressor Administration in Adults With Sepsis: A Retrospective Study of Guideline Adherence and Complications.","authors":"Spencer Mann, Susan H Weaver, Weddy Balmaceda, Mary Bobek, Melanie Cardona, Joan Harvey, Sharon Jones, Miriam McNicholas, Mani Paliwal, Deborah Prinzo, Marlene M Steinheiser","doi":"10.1097/NAN.0000000000000626","DOIUrl":"10.1097/NAN.0000000000000626","url":null,"abstract":"Background: Peripheral intravenous catheter (PIVC) vasopressor administration is increasingly used to expedite the treatment of septic shock when central venous access is not immediately available. This shift in practice reflects growing support from national guidelines, which permit short-term peripheral administration of vasopressors in adults. On March 9, 2023, hospitals within 1 health care system implemented guidelines for PIVC vasopressor administration in adult critical care settings, specifically emergency departments and intensive care units.Objective: This study examined adherence to these guidelines for PIVC vasopressor use and to identify associated complications.Methods: This retrospective descriptive study included 106 adult patients (68 emergency department and 38 intensive care unit patients) diagnosed with sepsis and receiving peripheral vasopressors.Results: The majority of patients received norepinephrine through a short PIVC. Overall, 5 patients (4.7%) experienced complications, 4 with thrombophlebitis and 1 with an extravasation. All 5 patients received norepinephrine at the organization's policy-specified concentration via short PIVCs. However, only 1 of these patients met the system's guidelines for minimum PIVC size, quantity, and maximum infusion duration. Overall, only 58% of patients were managed in full compliance with the system's guidelines.Conclusion: These results support the use of standardized protocols to reduce complications associated with short-term peripheral vasopressor administration.","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 1","pages":"13-21"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Valproate and Enteral Administration. 丙戊酸钠和肠内给药。

IF 1.2

Journal of Infusion Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1097/NAN.0000000000000628

Tiffany Khieu

引用次数: 0

Moving the Science Forward, One Study at a Time. 推动科学进步，一次一项研究。

IF 1.2

Journal of Infusion Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1097/NAN.0000000000000631

Susan Lown

引用次数: 0

Comparative Study on Warm Compress vs Cold Compress for Management of Peripheral Intravenous Catheter (PIVC)-Induced Pain and Phlebitis. 热敷与冷敷治疗外周静脉导管（PIVC）引起的疼痛和静脉炎的比较研究。

IF 1.2

Journal of Infusion Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1097/NAN.0000000000000622

Babli Shama, Shailja Sharma, Rajendra Kumar Jinjwaria

{"title":"Comparative Study on Warm Compress vs Cold Compress for Management of Peripheral Intravenous Catheter (PIVC)-Induced Pain and Phlebitis.","authors":"Babli Shama, Shailja Sharma, Rajendra Kumar Jinjwaria","doi":"10.1097/NAN.0000000000000622","DOIUrl":"10.1097/NAN.0000000000000622","url":null,"abstract":"This study aimed to evaluate the effectiveness of warm compress and cold compress in managing peripheral intravenous catheter (PIVC)-induced pain and phlebitis. A quantitative, pre-experimental 2-group pre-test post-test design was adopted, involving 60 purposively selected patients. Participants were divided into 2 groups on the basis of 2 different interventions: Group A (warm compress) and Group B (cold compress). Data were collected using a sociodemographic and clinical variables interview, Numerical Pain Rating Scale, and Visual Infusion Phlebitis (VIP) Scale. In Group A, the mean pain score decreased from 4.37 ± 1.00 to 1.97 ± 1.73, and the mean phlebitis score decreased from 3.20 ± 0.76 to 1.03 ± 0.89. In Group B, the mean pain score reduced from 4.33 ± 0.92 to 1.03, and the mean phlebitis score dropped from 3.24 ± 0.74 to 1.00 ± 0.53. The cold compress demonstrated slightly more effectiveness in relieving pain, whereas the warm compress showed marginally better outcomes in reducing phlebitis severity. No clinical variables were associated with post-test pain levels. However, a significant association was observed between the phlebitis score and type of drug administered (P = .04), suggesting that certain medications, such as antibiotics or inotropes, may influence the development or severity of phlebitis.","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 1","pages":"29-39"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 1.2

Journal of Infusion Nursing Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1097/NAN.0000000000000624

Chunlei Li, Zhongfang Yang, Xiaofeng He, Zhe Wang, Mayi Yang, Tianjun Zhou, Wenyan Pan, Ying Gu, Wenchao Wang, Yuxia Zhang, Yan Hu

{"title":"Catheter-Related Bloodstream Infections Among Critically Ill Patients With Central Vascular Access Devices: A Cross-Sectional Study in China.","authors":"Chunlei Li, Zhongfang Yang, Xiaofeng He, Zhe Wang, Mayi Yang, Tianjun Zhou, Wenyan Pan, Ying Gu, Wenchao Wang, Yuxia Zhang, Yan Hu","doi":"10.1097/NAN.0000000000000624","DOIUrl":"10.1097/NAN.0000000000000624","url":null,"abstract":"Objective: The aim of this study is to assess catheter-related bloodstream infections (CRBSIs) in Chinese intensive care units (ICUs), covering prevalence, risk factors, pathogen distribution, and impacts of outcome.Methods: A cross-sectional study was conducted in ICUs across 22 tertiary hospitals (2023-2024), with CRBSI diagnoses following Chinese national guidelines. Data were analyzed using R software (version 4.4.2), employing chi-square tests, robust Poisson regression, and Bayesian logistic regression (P < .05).Results: The prevalence of CRBSI was 1.19% (1.53/1000 catheter days, 32 patients, and 36 episodes). Risk factors included no formal education/illiteracy (OR: 1.995-9.604), circulatory diseases (OR: 1.142-5.787), complex/rare diseases (OR: 2.417-13.048), and multiple catheterizations (OR: 4.502-15.093). The subclavian vein was safest (femoral/axillary OR: 4.01-6.86). Gram-negatives predominated (47.22%). Each additional day of catheter dwell days increased CRBSI risk by 4.33% (95% CI: 3.04%-5.20%), and each additional ICU stay raised risk by 4.2% (95% CI: 2.9%-5.1%). CRBSI increased mortality (OR: 8.65), prolonged ICU stay (mean increase of 9.09 days), and additional costs (¥122 539.56 per case, approximately $17 505.65).Conclusion: CRBSI significantly worsens outcomes and costs in Chinese ICUs. Prioritizing subclavian catheterization, infection prevention bundles, and gram-negative antimicrobial stewardship is essential. Further research is needed to validate these interventions across diverse settings.","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"49 1","pages":"52-68"},"PeriodicalIF":1.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Piloting 4% Tetrasodium Ethylenediaminetetraacetic Acid (T-EDTA) Catheter Lock Solution in Renal Hemodialysis: A Quality Improvement Evaluation. 4%四钠乙二胺四乙酸（T-EDTA）置管锁液在肾血液透析中的应用：质量改进评价。

IF 1.2

Journal of Infusion Nursing Pub Date : 2025-11-01 Epub Date: 2025-10-24 DOI: 10.1097/NAN.0000000000000620

Kate McKey, Sarah Berger, Elizabeth Culverwell, Wendy Cuthill, Penny Hill

{"title":"Piloting 4% Tetrasodium Ethylenediaminetetraacetic Acid (T-EDTA) Catheter Lock Solution in Renal Hemodialysis: A Quality Improvement Evaluation.","authors":"Kate McKey, Sarah Berger, Elizabeth Culverwell, Wendy Cuthill, Penny Hill","doi":"10.1097/NAN.0000000000000620","DOIUrl":"https://doi.org/10.1097/NAN.0000000000000620","url":null,"abstract":"Central vascular access devices in renal hemodialysis patients have critical utility; nevertheless, they are associated with increased relative mortality risk compared to arteriovenous fistulas and grafts. Appropriate flushing and catheter locking are key to minimizing complication and dysfunction risk. Observational pre-post quality improvement evaluation was undertaken to evaluate 4% tetrasodium ethylenediaminetetraacetic acid (T-EDTA) catheter lock solution in renal hemodialysis. Four percent T-EDTA was piloted as the standard catheter lock solution (replacing 4 mg gentamicin/5000 IU per mL heparin lock). There was a 6-month evaluation period following product change, with retrospective comparison to 6 months prior. Outcome measures included bleeding complications post-insertion, catheter dysfunction, and catheter-related bloodstream infections (CR-BSI). SQUIRE 2.0 checklist for quality improvement reporting was used. Sixty-four catheters (4908 catheter days) (post) and 43 catheters (4603 catheter days) (pre) were evaluated. Bleeding complications post-catheter insertion (6% post; 38% pre), catheter dysfunction (minimal pre and post), CR-BSI (0.6 per 1000 catheter days post; 0.4 per 1000 catheter days pre) were observed. For the vulnerable population dependent on renal replacement therapy via renal hemodialysis catheters, 4% T-EDTA shows promise as a catheter lock solution, given no notable increase in CR-BSI or dysfunction, and a major reduction in post-catheter insertion bleeding was observed.","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"48 6","pages":"412-421"},"PeriodicalIF":1.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Vitro Venous Catheter Material Comparison: Microbial Adhesion in a Thrombotic Blood Flow Model. 体外静脉导管材料比较：血栓性血流模型中的微生物粘附。

IF 1.2

Journal of Infusion Nursing Pub Date : 2025-11-01 Epub Date: 2025-10-24 DOI: 10.1097/NAN.0000000000000615

Kristen LeRoy, Daniel Donahue

{"title":"In Vitro Venous Catheter Material Comparison: Microbial Adhesion in a Thrombotic Blood Flow Model.","authors":"Kristen LeRoy, Daniel Donahue","doi":"10.1097/NAN.0000000000000615","DOIUrl":"10.1097/NAN.0000000000000615","url":null,"abstract":"Objective: There is an ongoing need for intravenous catheters designed to reduce the risk of thrombosis and catheter-related bloodstream infections. The aim of this study was to compare thrombus formation and microbial adhesion on catheters made from hydrophilic biomaterial (HBM), thermoplastic polyurethane (TPU), and fluorinated TPU.Methods: Using the industry-recognized in vitro blood loop and static model, thrombus and microbial adhesion were quantified in the presence of 7 clinically relevant microbes.Results: Thrombotic and microbial adhesion to HBM catheters was significantly reduced in the presence of clinically relevant microbes. Thrombotic adhesion to HBM catheters showed a significant average reduction greater than 96.3% (2-tailed, paired; P ≤ . 03) for all microbes tested compared to TPU catheters. Compared to microbial adhesion to TPU catheters, HBM catheters averaged more than a 4-log reduction (>99.99% reduction) of microbial difference for all 7 microbes tested (2-tailed, paired; P ≤ .003 for all microbes). Reductions in thrombotic and microbial adhesions were independent of clotting factors.Conclusions: Although large clinical trials are needed, these in vitro results build on the growing evidence to support the use of HBM catheters to prevent common complications associated with vascular access devices.","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"48 6","pages":"386-394"},"PeriodicalIF":1.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12551418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of 70% Isopropyl Alcohol-Impregnated Disinfecting Caps on Needleless Connector Colonization in Ambulatory Pediatric Hematology-Oncology Patients. 70%异丙醇浸渍消毒帽对流动儿科血液肿瘤患者无针接头定植的影响

IF 1.2

Journal of Infusion Nursing Pub Date : 2025-11-01 Epub Date: 2025-10-24 DOI: 10.1097/NAN.0000000000000612

İlker Devrim, Hincal Ozbakir, Miray Yilmaz Celebi, Rukiye Bulut, Şerife Şebnem Önen Göktepe, Sevgi Seda Çığırgan, Begümhan Demir Gündoğan, Feray Fatma Aslan, İlker Yavuz, Canan Dinc, Yeliz Oruc, Arzu Bayram, Fahri Yüce Ayhan, Tuba Hilkay Karapınar, Nuri Bayram

{"title":"The Impact of 70% Isopropyl Alcohol-Impregnated Disinfecting Caps on Needleless Connector Colonization in Ambulatory Pediatric Hematology-Oncology Patients.","authors":"İlker Devrim, Hincal Ozbakir, Miray Yilmaz Celebi, Rukiye Bulut, Şerife Şebnem Önen Göktepe, Sevgi Seda Çığırgan, Begümhan Demir Gündoğan, Feray Fatma Aslan, İlker Yavuz, Canan Dinc, Yeliz Oruc, Arzu Bayram, Fahri Yüce Ayhan, Tuba Hilkay Karapınar, Nuri Bayram","doi":"10.1097/NAN.0000000000000612","DOIUrl":"https://doi.org/10.1097/NAN.0000000000000612","url":null,"abstract":"Objective: Totally implantable venous access devices (TIVADs) are essential in pediatric oncology but pose a risk of catheter-related infections. This study assesses the impact of 70% isopropyl alcohol-impregnated disinfecting caps on microbial colonization of needleless connectors (NCs) and extension set lumens.Design: This is a single-center, open-label, prospective study.Participants: The study included 23 pediatric patients (50 treatment episodes) with acute lymphoblastic leukemia using TIVADs.Methods: From April to July 2024, patients with double-lumen extension sets and needleless connectors (NCs) were included. One NC remained uncovered, while the other was capped with a 70% alcohol-impregnated disinfecting cap. Surface cultures were obtained from the uncovered NC on days 2, 3, and 4, and from the capped NC on day 4.Results: Microbial colonization was significantly higher in uncovered NCs (63.3%) than in capped NCs (2%) (P < .001). Coagulase-negative staphylococci were the predominant isolates (88.4%). Intraluminal colonization was also higher in uncovered NCs (76% vs. 6%; P < .001).Conclusion: Alcohol-impregnated disinfecting caps significantly reduce microbial colonization of NCs and extension set lumens in pediatric oncology patients, suggesting their effectiveness in infection prevention.","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"48 6","pages":"406-411"},"PeriodicalIF":1.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Tunneled vs Traditional PICCs in Cancer Patients: A Propensity Score-Matched Study. 肿瘤患者隧道与传统PICCs的比较：一项倾向评分匹配研究。

IF 1.2

Journal of Infusion Nursing Pub Date : 2025-11-01 Epub Date: 2025-10-24 DOI: 10.1097/NAN.0000000000000616

Ting Lu, Yi Xu, Jiejing Wei, Yanping Ying

{"title":"Comparison of Tunneled vs Traditional PICCs in Cancer Patients: A Propensity Score-Matched Study.","authors":"Ting Lu, Yi Xu, Jiejing Wei, Yanping Ying","doi":"10.1097/NAN.0000000000000616","DOIUrl":"https://doi.org/10.1097/NAN.0000000000000616","url":null,"abstract":"Objective: The aim of the study was to compare complication rates and laboratory outcomes between tunneled and conventional peripherally inserted central catheters (PICCs) in cancer patients using propensity score matching (PSM).Methods: This single-center retrospective cohort study, which took place from 2021 to 2023, included 418 patients. After 1:1 PSM, 113 matched patients were analyzed in each group. Complication rates and laboratory indicators were compared. Logistic regression was used to identify risk factors for infection and catheter displacement.Results: Compared to traditional PICCs, tunneled PICCs were associated with lower infection (6.19% vs 17.70%; P = .014), phlebitis (0% vs 27.43%; P < .001), and catheter displacement rates (33.63% vs 60.18%; P < .001). Regression analysis confirmed reduced risks of infection (OR = 3.257, 95% CI: 1.32-8.02; P = .011) and displacement (OR = 2.982, 95% CI: 1.81-4.91; P < .001). Laboratory analysis showed significantly higher white blood cell (WBC) levels, neutrophil percentages, absolute neutrophil counts, and prothrombin time in the tunneled group (P < .05). In contrast, lymphocyte percentage and monocyte percentage were lower in the tunneled group (P < .05).Conclusions: Tunneled PICCs may provide a safer and more stable vascular access option than conventional PICCs in oncology patients. Further prospective studies are warranted.","PeriodicalId":46291,"journal":{"name":"Journal of Infusion Nursing","volume":"48 6","pages":"422-432"},"PeriodicalIF":1.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145453778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0